[KSCI] Korea Science Citation Index Service

Study of Effects of Harpagophyti Radix on Edema and Blood of Rats with Arthritis

Lee Joung Hun (Department of Anatomy-Meridian, College of Oriental Medicine, Kyungwon University)
Kim Youn-Sub (Department of Anatomy-Meridian, College of Oriental Medicine, Kyungwon University)

Publication Information

Journal of Physiology & Pathology in Korean Medicine / v.18, no.2, 2004 , pp. 446-450 More about this Journal

Abstract

Objectives: In order to study the effects of Harpagophyti Radix in rats with arthritis induced by Freund's complete adjuvant. Methods : In this study, rats with arthritis induced by Freund's complete adjuvant were divided into four groups; Normal, Control, Sample A(Harpagophyti Radix 6mg/200g) and Sample B(Harpagophyti Radix 12mg/200g). After 1 week, separated searches were made on the change of edema rate, the count of WBC, the quantity of total protein, total bilirubin, GOT and GPT in the serum. Results: In the right plantar edema, both of Sample groups showed a decrease in comparison with Control group. In the count of WBC, the quantity of serum total protein and SGOT, Sample B showed a decrease with statistical significance in comparison with Control group. In the quantity of serum total bilirubin and SGPT, both of Sample groups did not show any harmful change in in comparison with Control group. Conclusion : Reviewing these experimental results, it appeared that Harpagophyti Radix showed the therapeutic effect of anti-inflammatation on adjuvant arthritis.

Keywords

Harpagophyti Radix; arthritis; edema rate; count of WBC;

Citations & Related Records

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KSCI

Study of Effects of Harpagophyti Radix on Edema and Blood of Rats with Arthritis 관절염 백선의 부종과 혈액에 미치는 천수근의 효능연구

Study of Effects of Harpagophyti Radix on Edema and Blood of Rats with Arthritis