• JSTS:Journal of Semiconductor Technology and Science
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• 제15권2호
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• pp.276-279
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• 2015

This paper presents two 3-stage D-band stacked amplifiers developed in a $0.13-{\mu}m$ SiGe BiCMOS technology, employed to compare the conventional cascode topology and the common-base (CB)/CB stacked topology. AMP1 employs two cascode stages followed by a CB/CB stacked stage, while AMP2 is composed of three CB/CB stacked stages. AMP1 showed a 17.1 dB peak gain at 143.8 GHz and a saturation output power of -4.2 dBm, while AMP2 showed a 20.4 dB peak gain at 150.6 GHz and a saturation output power of -1.3 dBm. The respective power dissipation was 42.9 mW and 59.4 mW for the two amplifiers. The results show that CB/CB stacked topology is favored over cascode topology in terms of gain near 140 GHz.

• 한국식물병리학회지
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• 제10권4호
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• pp.254-260
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• 1994

Magnaporthe grisea, a causal agent of blast, forms a specialized infection structure, an appressorium, to infect host. Hydrophobicity of contact surface and cAMP have been suggested as a primary environmental signal and a second messenger to trigger and mediate appressorium formation in this fungus, respectively. To generalize these factors in field isolates of M. girsea, twenty isolates originated from rice and other gramineous hosts were tested. Seventeen including rice and non-rice isolates formed appressoria on hydrophobic surface, but none of isolates formed appressoria on hydrophilic surface. Eighteen isolates formed appressoria on hydrophilic surface in the presence of IBMX, an inhibitor of phosphodiesterase, except two rice isolates. These results strongly support the hypothesis that appressorium formation by M. grisea is induced by hydrophobic hard surface and regulated by the endogenous level of cAMP in the cells. Understanding fungal development is not only of biological interest but provides new targets for novel disease control strategies.

• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2002년도 추계학술발표논문집 (중)
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• pp.1587-1590
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• 2002

Active Measurement Program(AMP)는 능동 모니터들이 서로 대칭적으로 모든 모니터들에 대해서 능동 성능 측정을 하는 분산 네트워크 시스템이다. 본 연구에서는 KREONET 의 성능 측정을 위하여, AMP 서버 및 모니터 구축, 모니터링 지역 선정 기준 정의, AMP MIB 정의를 통한 효과적인 AMP KREONET 구축 방안을 설명한다.

• 동아시아식생활학회지
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• 제6권1호
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• pp.51-58
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• 1996

무우에 함유된 allylisothiocyanate의 첨가가 Aspergillus parasiticus R-716의 배양시 sterigmatocystin, 지질, 단백질, RNA, citrate 및 AMP 등의 각종 대사산물의 생합성에 미치는 영향을 조사하였다. 그 결과 aflatoxin의 전구체인 sterigmatocystin의 함량은 배양 48시간 후에는 50ppm allyli-sothiocyanate 첨가구가 대조구보다 낮게 나타난 반면, 144시간째부터는 첨가구가 대조구보다 오히려 높게 나타났다. Allylisothiocyanate의 첨가로 Aspergillus parasiticus R-716의 배양액에서 citrate는 높은 함량을 나타내었으며, 또한 균체내 지질, 단백질, RNA의 함량은 높게 나타났으나 AMP 함량은 낮았다.

• Archives of Pharmacal Research
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• 제19권6호
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• pp.520-528
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• 1996

The involvement of the cyclic AMP (cAMP) effector system in the release of endogenous dopamine and acetylcholine from the rat neostriatum was assessed. Forskolin, an activator of adenylate cyclase, was used to enhance cAMP production, and the consequence of this enhancement on the spontaneous and potassium stimulated release of dopamine and acetylcholine was evaluated. Neostriatal slices were prepared from Fischer 344 rats and after a preincubation period the release of each endogenous neurotransmitter was measured from the same slice preparation. To measure acetylcholine release the slice acetylcholinesterase (AChE) activity was inhibited with physostigmine, but the release from slices with intact AChE activity was also determined (choline, instead of acetylcholine was detected in the medium). Under both conditions forskolin induced a significant dose-dependent increase in the potassium-evoked release of dopamine. In the same tissue preparations the release of neither acetylcholine (AChE inhibited) nor choline (AChE intact) was affected by forskolin. The results indicate that the CAMP second messenger system might be involved in neuronal mechanisms that enhance neostriatal dopamine release, but stimulation of this second messenger by forskolin does not further enhance neostriatal acetylcholine release.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1993년도 하계학술대회 논문집 A
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• pp.479-482
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• 1993

A fully balanced differential amplifier can achieve high-gain wide-bandwidth characteristics. And also, Offset PSRR, CMRR and Noise performance of that are excellent, but these merits can be achieved only when the architecture holds fully balanced. Commonly, the fully balanced differential amplifier has a common mode feedback(CMFB) circuit in order to maintain the balance. This paper presents improved characteristics of the CMFB circuit and designs the wide-bandwidth CMOS Op-amp. The unity gain bandwidth of this Op-amp is 50MHz with the load capacitor 2pF, and the value of phase margin is $85^{\circ}$.

• 전력전자학회:학술대회논문집
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• 전력전자학회 2015년도 전력전자학술대회 논문집
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• pp.149-150
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• 2015

압전 마이크로머신 초음파 트랜스듀서(Piezoelectric micro-machined ultrasonic transducers)는 DC 바이어스 전압을 인가해야 구동되는 특성을 가지고 있다. 따라서 초음파 트랜스 듀서를 구동하기 위한 전력증폭기는 DC 바이어스 전압이 요구되므로 기존의 전력증폭기에 비해 효율이 매우 낮아지게 된다. 이를 해결하기 위해 본 논문에서는 압전 마이크로머신 초음파 트랜스듀서를 구동하기 위한 고효율 전력증폭기를 제안한다. 전력증폭기는 AMP부와 전원부로 나뉘며, AMP부는 Class B Amp를 사용하여 높은 증폭 선형성을 갖는다. 전원부는 Amp를 구동하기위한 DC-DC converter가 에너지 회수 동작을 하므로 전력증폭기의 효율을 높일 수 있다. 본 연구에서는 압전 마이크로머신 초음파 트랜스듀서를 구동하기 위한 전력증폭기 회로를 제시하고 시뮬레이션과 실험을 통해 동작 특성을 검증한다.

• 대한치과교정학회지
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• 제54권1호
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• pp.69-73
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• 2024

Since its inception in Europe in the 1950s, alveolar molding treatment for neonates with complete cleft lip and palate has undergone significant evolution in both design and application methodology, demonstrating effectiveness in normalizing the alveolar cleft and nasal shape. However, excessively wide alveolar clefts accompanied by disproportionately wide total maxillary arch pose significant challenges when utilizing conventional alveolar molding methods involving cyclical adding and grinding of acrylic on molding plates. The current report introduces a novel alveolar molding method named Biocreative Alveolar Molding Plate Treatment (BioAMP), which can normalize the maxillary alveolar cleft and arch shape without laborious conventional acrylic procedures. BioAMP sets the target arch form and provides unrestricted space for natural growth of the maxillary alveolar bones while systematically reducing the total maxillary arch width in precise increments. Two exemplary cases are presented as proof-of-concept, showcasing the clinical innovation of BioAMP.

• 한국미생물·생명공학회지
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• 제51권3호
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• pp.309-313
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• 2023

Here we report essential features of the draft genome of an AmpC-β-lactamase-producing bacterial isolate obtained from farm tomatoes in South Africa. The isolate designated strain Tom1 featured a genome of 4950426 bp with a G+C% of 59.83. It was identified as Serratia marcescens by ribosomal multilocus sequence typing (rMLST), digital DNA-DNA hybridization (dDDH), average nucleotide identity (ANI), and phylogenetic analysis using reference genomes. Its genome encoded an AmpC-β-lactamase (bla_SST-1), an efflux pump providing tetracycline resistance (tet(41)), and an aminoglycoside acetyltransferase (aac(6')-Ic). Additionally, genes encoding proteins involved in prodigiosin biosynthesis and associated with adherence, biofilm formation, virulence, and pathogenicity were detected.

• The Korean Journal of Physiology and Pharmacology
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• 제19권2호
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• pp.89-97
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• 2015

The aim of this study was to investigate the involvement of dopaminergic receptors (DR) in behavioral sensitization, as measured by locomotor activity, and the over-expression of cocaine- and amphetamine-regulated transcript (CART) peptides after repeated administration of cocaine in mice. Repeated administrations of cocaine induced behavioral sensitization and CART over-expression in mice. The levels of striatal CART mRNA were significantly increased on the $3^{rd}$ day. CART peptides were over-expressed on the $5^{th}$ day in the striata of behaviorally sensitized mice. A higher proportion of $CART^+$ cells in the cocaine-treated mice were present in the nucleus accumbens (NAc) shell than in the dorsolateral (DL) part of caudate putamen (CP). The concomitant administration of both $D_1R$ and $D_2R$ antagonists, SCH 23390 ($D_1R$ selective) and raclopride ($D_2R$ selective), blocked cocaine induced-behavioral sensitization, CART over-expression, and cyclic adenosine 5'-monophosphate (cAMP)/ protein kinase A (PKA)/phospho-cAMP response element-binding protein (pCREB) signal pathways. SCH 23390 more predominantly inhibited the locomotor activity, CART over-expression, pCREB and PKA activity than raclopride. Cocaine induced-behavioral sensitization was also attenuated in the both $D_1R$ and $D_2R$ knockout (KO) mice, respectively. CART over-expression and activated cAMP/PKA/pCREB signal pathways were inhibited in the $D_1R$-KO mice, but not in the $D_2R$-KO mice. It is suggested that behavioral sensitization, CART over-expression and activated cAMP/PKA/pCREB signal pathways induced by repeated administration of cocaine could be more predominantly mediated by $D_1R$.