• Journal of Korean Philosophical Society
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• v.142
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• pp.27-50
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• 2017

When we lose our memories or when our self-identity becomes blurred, we may feel as if our mind has split into multiple minds. If someone makes another 'me' by copying my body and mind, how should two conscious 'I's change their credences? In this article, we present a new thought experiment that can be called the 'Two Adams Problem'. This thought experiment represents a piece of philosophical inquiry that speculates on the nature of self-consciousness information that 'I am awake now'. On Sunday evening, as soon as Adam falls asleep, the philosopher Roro makes another Adam by copying Adam's original body and mind. They sleep separately in another room. Within a minute, Roro throws a fair coin. If the coin lands heads up Roro wakes just one of the Adams up on Monday. If the coin lands tails up Roro wakes both Adams up. On Monday, at least one of the Adams will wake up. To what degree ought they believe that the outcome of the coin toss is heads? We will argue that the correct answer to this question is 1/2.

• Korean Journal of Logic
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• v.22 no.1
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• pp.1-23
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• 2019

Gott, Carter, Leslie, Bostrom and so on, as Descartes did, have made the evidence that is "I am here as an observer" to support many other beliefs. Bostrom and others who studied observation selection effects are missing two points. First, the self-consciousness information of the ones who just came up is distinct from that of the ones who have awoken. The awoken 'I' can trace back by memory to the past, but the 'I' who just came up can not. Second, when calculating credence, we must distinguish the ones in the possible worlds from the ones in the actual worlds. An estimate of credence where only one possible world is actualized among all possible worlds, differs fundamentally from that where all possible worlds are actualized. Keeping these two points in mind, we have explored what is the nature of the self-consciousness information of the one who just came up. We examine in depth the two human embryos thought experiment.

• BMB Reports
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• v.54 no.10
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• pp.516-521
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• 2021

Although arginase primarily participates in the last reaction of the urea cycle, we have previously demonstrated that arginase II is an important cytosolic calcium regulator through spermine production in a p32-dependent manner. Here, we demonstrated that rhaponticin (RPT) is a novel medicinal-plant arginase inhibitor and investigated its mechanism of action on Ca²⁺-dependent endothelial nitric oxide synthase (eNOS) activation. RPT was uncompetitively inhibited for both arginases I and II prepared from mouse liver and kidney. It also inhibited arginase activity in both aorta and human umbilical vein endothelial cells (HUVECs). Using both microscope and FACS analyses, RPT treatments induced increases in cytosolic Ca²⁺ levels using Fluo-4 AM as a calcium indicator. Increased cytosolic Ca²⁺ elicited the phosphorylations of both CaMKII and eNOS Ser1177 in a time-dependent manner. RPT incubations also increased intracellular L-arginine (L-Arg) levels and activated the CaMKII/AMPK/Akt/eNOS signaling cascade in HUVECs. Treatment of L-Arg and ABH, arginase inhibitor, increased intracellular Ca²⁺ concentrations and activated CaMKII-dependent eNOS activation in ECs of WT mice, but, the effects were not observed in ECs of inositol triphosphate receptor type 1 knockout (IP3R1^-/-) mice. In the aortic endothelium of WT mice, RPT also augmented nitric oxide (NO) production and attenuated reactive oxygen species (ROS) generation. In a vascular tension assay using RPT-treated aortic tissue, cumulative vasorelaxant responses to acetylcholine (Ach) were enhanced, and phenylephrine (PE)-dependent vasoconstrictive responses were retarded, although sodium nitroprusside and KCl responses were not different. In this study, we present a novel mechanism for RPT, as an arginase inhibitor, to increase cytosolic Ca²⁺ concentration in a L-Arg-dependent manner and enhance endothelial function through eNOS activation.

• Korean Journal of Acupuncture
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• v.38 no.3
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• pp.162-174
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• 2021

Objectives : We aimed to identify the antidepressant effect of liver tonification acupuncture treatment (ACU (LT); KI10, LR8, LU8, LR4) and four gate acupuncture treatment (ACU (FG); LI4, LR3) and its brain neural activity in the normal and chronic restraint stress (CRS)-induced mouse model. Methods : Firstly, normal mice were given ACU (LT) or ACU (FG) and the c-Fos expressions in each brain region were analyzed to examine brain neural activity. Secondly, CRS was administered to mice for 4 weeks, then ACU (LT) or ACU (FG) was performed for 2 weeks. The depression-like behavior was evaluated using open field test (OFT) before and after acupuncture treatment. Then, the c-Fos expressions in each brain region were analyzed to examine brain neural activity. Results : In normal mice, ACU (FG) regulated brain neural activities in the hypothalamus, hippocampus, and periaqueductal gray. ACU (LT) changed more brain regions in the prefrontal cortex, insular cortex, striatum, and hippocampus, including those altered by ACU (FG). In CRS-induced model, ACU (LT) alleviated depression-like behavior more than ACU (FG). Also, brain neural activities in the motor cortex area 2 (M2), agranular ventral part and piriform of insular cortex (AIV and Pir), and cornu ammonis (CA) 1 and CA3 of hippocampus were changed by ACU (LT), and those of AIV and CA3 were also changed by ACU (FG). As in normal mice, ACU (LT) resulted in changes in more brain regions, including those altered by ACU (FG) in CRS model. M2, Pir, and CA1 were only changed by ACU (LT) in depression model, suggesting that these brain regions reflect the specific effect of ACU (LT). Conclusions : ACU (LT) relieved depression-like behavior more than ACU (FG), and this acupuncture effect was associated with modulation of brain neural activities in the motor cortex, insular cortex, and hippocampus.

• Journal of the Korean Society of Radiology
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• v.13 no.4
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• pp.667-674
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• 2019

Because examination with technegas produces images through simple diffusion accumulation, the examination room can become contaminated after scan. Therefore, radiation workers and patients awaiting examination will be affected by internal exposure from technegas inhalation. Before and after gravity ventilation, I am trying to find a way to reduce the exposure dose of waiting patients according to a comparative analysis of horizontal spatial dose rates over time. Spatial dose ratio were measured for 10 minutes from various distances and angles around ventilator's location before and after gravity ventilation. Then, mean values, standard deviation and reduction ratio were calculated. The highest reduction rate of gravity ventilation was 95.31% and the highest reduction ratio was 1 to 3 minutes. Therefore, the gravity ventilation could reduce the exposure dose of radiologic technologists, waiting patients, patient guardians and nurses. In conclusion, the reduction of the exposure dose during the technegas ventilation study through gravity ventilation will play a role in optimiging the protection and it is in accordance with the recommended reduction of the medical exposure by ICRP 103.

• 한국체육학회지인문사회과학편
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• v.58 no.1
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• pp.271-284
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• 2019

The purpose of this study was to analyze effects of 12 weeks dance sports on body composition, irisin, adiponectin and blood lipids in obesity elderly women. The subjects were 26 obesity elderly women who do not have medically problems. The subjects randomly assigned to two groups; dance sports exercise(n=13), control(n=13). The subjects in dance sports group were participated for 60 minutes/day with two times/wk for 12 weeks, whereas subjects in control group were asked to maintain normal lifestyle during the same intervention period. The results of the present study showed that the blood irisin was significantly increased in the exercise group. The blood adiponectin level tended to increase in the exercise gorup. The blood lipids, TG and LCL-C were significantly decreased in the exercise group. The TC was slightly decreased, and the HDL-C was slightly increased. In conclusion, low irisin and adiponectin level in obese people have a positive effect on obese elderly women after dance sports. Therefore, exercise is thought to be good for the care of elderly obesity.

• The Journal of the Convergence on Culture Technology
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• v.7 no.1
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• pp.234-239
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• 2021

The purpose of this paper is to find out the nature of language variation by exploring the ways of the progress of the language variation that produces all English-lects, i.e., the World Englishes. The study of language variation in linguistics is a hybrid enterprise, so the study of World Englishes has led to the recognition of a highly diverse set of all English-lects, encompassing regional dialects, sociolects, ethnolects and (post-)colonial dialects of World Englishes. In this paper, we propose a hybrid language variation model with three interacting factors of social distancing, on/off-contact, and linguistic diversity to examine the characteristics of language variation. In the context of World Englishes, the social distance is typically low in terms of their local location (country/speech) for local purposes. The social distance also varies based on online/offline communication modes and other social factors like gender, age and ethnic groups, resulting in all English-lects. To clarify the nature of World Englishes, the core Englishes, BrE, AmE and CanE are discussed here.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.1
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• pp.402-408
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• 2021

Vehicle engineering analysis in the event of an accident caused by a car built on mechanical design has not been investigated in-depth but relies on the subjective experience knowledge of the investigator. This study analyzed the correlation between the speed, progress, steering, and braking before impact, which is consistent with the final stop position, by drawing a site situation chart using the CAD (CAD) program and repeating 250 crashes using the PC-Crash program. The following situations were investigated: lower impact velocity; greater impact speed of the vehicle, which is not affected significantly by the departure angle; higher vehicle speed, such as the effective impact velocity, after the impact; higher vehicle speed; and lower vehicle speed. (Ed note: I am unsure what you are saying here. It appears contradictory and not a complete sentence. Please check the changes.)The simulation results of this study identified the process of returning to the magnetic progression lane after recognizing the opposite porter while Mighty was carried out on the uphill left-curve section in a position that crossed the center line, and the collision of the porter's front left side, pushing the porter in the right diagonal direction and making the front stop towards approximately 11 o'clock.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.25 no.3
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• pp.339-345
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• 2021

With the development of online education due to COVID-19, the EduTech market, which combines new technologies such as AI and AR/VR in education is rapidly growing. In addition, the children's industry is steadily growing despite the decreasing birth rate every year as more and more families with one child per household are investing in their children. However, supply of contents to EduTech market is slow compared to demands that are increasing. Therefore, the purpose of this paper is to help solve these problems by developing and supporting AR kids contents with convenience, practicality, and efficiency using AR technology. AR content for supporting vocabulary learning for infants is not just an end to watching and listening, but an observation-driven model that can manipulate content directly, which attracts children's interest and helps children learn words. This paper is intended for infants from 15 months to 36 months old when full-fledged language development occurs.

• Current Optics and Photonics
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• v.6 no.2
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• pp.183-190
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• 2022

Based on the linear electro-optic (EO) effect of lithium niobite (LiNbO₃, LN) crystal, an intense two-dimensional (2D) electric field sensor was analyzed, fabricated and experimentally demonstrated. The linear polarized light beam transmits along the optical axis (z-axis) of the LN crystal, and the polarization direction of the polarized light is 45° to the y-axis. The sensor can detect the intensity of a 2D electric field that is perpendicular to the z-axis. Experimental results demonstrated that the minimum detectable electric field of the sensor is 10.5 kV/m. The maximum detected electric field of the sensor is larger than 178.9 kV/m. The sensitivity of the sensor is 0.444 mV/(kV·m^-1). The variation of the sensitivity is within ±0.16 dB when the sensor is rotated around a z-axis from 0° to 360°. The variation of the sensor output optical power is within ±1.4 dB during temperature change from 19 ℃ to 26 ℃ in a day (from 7:00 AM to 23:00 PM) and temperature change from 0 ℃ to 40 ℃ in a controllable temperature chamber. All theoretical and experimental results revealed that the fabricated sensor provides technology for the direct detection of intense 2D electric fields.