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Clinical and Epidemiological Characteristics of Common Human Coronaviruses in Children: A Single Center Study, 2015-2019

  • Choi, Youn Young;Kim, Ye Kyung;Choi, Eun Hwa
    • Pediatric Infection and Vaccine
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    • v.28 no.2
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    • pp.101-109
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    • 2021
  • Purpose: Common human coronaviruses (HCoVs) are relatively understudied due to the mild nature of HCoV infection. Given the lack of local epidemiology data on common HCoVs, we aimed to describe clinical and epidemiological characteristics of common HCoVs in children. Methods: Respiratory viral test results from 9,589 respiratory samples from Seoul National University Children's Hospital were analyzed from January 2015 to December 2019. Viral detection was done by the multiplex reverse transcription polymerase chain reaction. Demographics and clinical diagnosis were collected for previously healthy children tested positive for HCoVs. Results: Of the 9,589 samples tested, 1 or more respiratory viruses were detected from 5,017 (52.3%) samples and 463 (4.8%) samples were positive for HCoVs (OC43 2.8%, NL63 1.4%, 229E 0.7%). All 3 types co-circulated during winter months (November to February) with some variation by type. HCoV-OC43 was the most prevalent every winter season. HCoV-NL63 showed alternate peaks in late winter (January to March) and early winter (November to February). HCoV-229E had smaller peaks every other winter. Forty-one percent of HCoV-positive samples were co-detected with additional viruses; human rhinovirus 13.2%, respiratory syncytial virus 13.0%, influenza virus 4.3%. Common clinical diagnosis was upper respiratory tract infection (60.0%) followed by pneumonia (14.8%), croup (8.1%), and bronchiolitis (6.7%). Croup accounted for 17.0% of HCoV-NL63-positive children. Conclusions: This study described clinical and epidemiological characteristics of common HCoVs (OC43, NL63, 229E) in children. Continuing surveillance, perhaps by adding HKU1 in the diagnostic panel can further elucidate the spectrum of common HCoV infections in children.

Identification of Bird Community Characteristics by Habitat Environment of Jeongmaek Using Self-organizing Map - Case Stuty Area Geumnamhonam and Honam, Hannamgeumbuk and Geumbuk, Naknam Jeongmaek, South Korea - (자기조직화지도를 활용한 정맥의 서식지 환경에 따른 조류 군집 특성 파악 - 금남호남 및 호남정맥, 한남금북 및 금북정맥, 낙남정맥을 대상으로 -)

  • Hwang, Jong-Kyeong;Kang, Te-han;Han, Seung-Woo;Cho, Hae-Jin;Nam, Hyung-Kyu;Kim, Su-Jin;Lee, Joon-Woo
    • Korean Journal of Environment and Ecology
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    • v.35 no.4
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    • pp.377-386
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    • 2021
  • This study was conducted to provide basic data for habitat management and preservation of Jeongmaek. A total of 18 priority research areas were selected with consideration to terrain and habitat environment, and 54 fixed plots were selected for three types of habits: development, valley, and forest road and ridge. The survey was conducted in each season (May, August, and October), excluding the winter season, from 2016 to 2018. The distribution analysis of birds observed in each habitat type using a self-organizing map (SOM) classified them into a total of four groups (MRPP, A=0.12, and p <0.005). The comparative analysis of the number of species, the number of individuals, and the species diversity index for each SOM group showed that they were all the highest in group III (Kruskal-Wallis, the number species: x2 = 13.436, P <0.005; the number of individuals: x2 = 8.229, P <0.05; the species diversity index: x2 = 17.115, P <0.005). Moreover, the analysis by applying the land cover map to the random forest model to examine the index species of each group and identify the characteristics of the habitat environment showed a difference in the ratio of the habitat environment and the indicator species among the four groups. The index species analysis identified a total of 18 bird species as the indicator species in three groups except for group II. When applying the random forest model and indicator species analysis to the results of classification into four groups using the SOM, the composition of the indicator species by the group showed a correlation with the habitat characteristics of each group. Moreover, the distribution patterns and densities of observed species were clearly distinguished according to the dominant habitat for each group. The results of the analysis that applied the SOM, indicator species, and random forest model together can derive useful results for the characterization of bird habitats according to the habitat environment.

Trends in QA/QC of Phytoplankton Data for Marine Ecosystem Monitoring (해양생태계 모니터링을 위한 식물플랑크톤 자료의 정도 관리 동향)

  • YIH, WONHO;PARK, JONG WOO;SEONG, KYEONG AH;PARK, JONG-GYU;YOO, YEONG DU;KIM, HYUNG SEOP
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.26 no.3
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    • pp.220-237
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    • 2021
  • Since the functional importance of marine phytoplankton was firstly advocated from early 1880s massive data on the species composition and abundance were produced by classical microscopic observation and the advanced auto-imaging technologies. Recently, pigment composition resulted from direct chemical analysis of phytoplankton samples or indirect remote sensing could be used for the group-specific quantification, which leads us to more diversified data production methods and for more improved spatiotemporal accessibilities to the target data-gathering points. In quite a few cases of many long-term marine ecosystem monitoring programs the phytoplankton species composition and abundance was included as a basic monitoring item. The phytoplankton data could be utilized as a crucial evidence for the long-term change in phytoplankton community structure and ecological functioning at the monitoring stations. Usability of the phytoplankton data sometimes is restricted by the differences in data producers throughout the whole monitoring period. Methods for sample treatments, analyses, and species identification of the phytoplankton species could be inconsistent among the different data producers and the monitoring years. In-depth study to determine the precise quantitative values of the phytoplankton species composition and abundance might be begun by Victor Hensen in late 1880s. International discussion on the quality assurance of the marine phytoplankton data began in 1969 by the SCOR Working Group 33 of ICSU. Final report of the Working group in 1974 (UNESCO Technical Papers in Marine Science 18) was later revised and published as the UNESCO Monographs on oceanographic methodology 6. The BEQUALM project, the former body of IPI (International Phytoplankton Intercomparison) for marine phytoplankton data QA/QC under ISO standard, was initiated in late 1990. The IPI is promoting international collaboration for all the participating countries to apply the QA/QC standard established from the 20 years long experience and practices. In Korea, however, such a QA/QC standard for marine phytoplankton species composition and abundance data is not well established by law, whereas that for marine chemical data from measurements and analysis has been already set up and managed. The first priority might be to establish a QA/QC standard system for species composition and abundance data of marine phytoplankton, then to be extended to other functional groups at the higher consumer level of marine food webs.

Health and nutrition intake status of the Korean elderly according to their food security level: data from the 7th Korea National Health and Nutrition Examination Survey (KNHANES VII), 2016-2018 (식품안정성 수준에 따른 한국노인의 건강상태와 영양섭취현황: 제7기 (2016-2018) 국민건강영양조사 자료 활용)

  • Maeng, Ahreum;Lee, Jeehyun;Yoon, Eunju
    • Journal of Nutrition and Health
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    • v.54 no.2
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    • pp.179-198
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    • 2021
  • Purpose: This study examined general characteristics, health status, accessibility to medical services, health-related quality of life, dietary behavior, and energy and nutrient intakes of the elderly at different levels of food security utilizing data from the 7th Korea National Health and Nutrition Examination Survey (2016-2018). Methods: The elderly subjects (1,721 males and 2,271 females) were divided into 3 groups (secure, mildly insecure, moderately/severely insecure) according to their food security levels. Health and nutrient status was determined using energy intake, nutrient density, the prevalence of insufficient nutrient intake, dietary behavior, and health status. Results: The elderly with food insecurities had a lower self-evaluated health status and a higher prevalence of physician-diagnosed chronic diseases such as arthritis, osteoarthritis, rheumatoid arthritis, osteoporosis for males, and hypertension, stroke, arthritis, and osteoarthritis for females. The associated financial burden was the major reason for not accessing medical services in the food insecure group. Furthermore, the food insecure group had a higher risk of impaired health-related quality of life compared to the secure group. The proportion of subjects with an energy intake below the estimated energy requirement was higher in the food insecure group and a significantly higher prevalence of insufficient intake was observed for all the nutrients (proteins, vitamin A, vitamin B1, vitamin B2, niacin, vitamin C, calcium, and iron) assessed in this study compared to the food secure group. Conclusion: This study suggests that food insecurity poses a challenge to the health and nutritional status of the elderly population in Korea and needs proper management. It would be helpful to develop food and nutrition assistance programs to ensure the food stability of the elderly population and assure quality to address gaps in their nutrient intake.

Estimation of the Lodging Area in Rice Using Deep Learning (딥러닝을 이용한 벼 도복 면적 추정)

  • Ban, Ho-Young;Baek, Jae-Kyeong;Sang, Wan-Gyu;Kim, Jun-Hwan;Seo, Myung-Chul
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.66 no.2
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    • pp.105-111
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    • 2021
  • Rice lodging is an annual occurrence caused by typhoons accompanied by strong winds and strong rainfall, resulting in damage relating to pre-harvest sprouting during the ripening period. Thus, rapid estimations of the area of lodged rice are necessary to enable timely responses to damage. To this end, we obtained images related to rice lodging using a drone in Gimje, Buan, and Gunsan, which were converted to 128 × 128 pixels images. A convolutional neural network (CNN) model, a deep learning model based on these images, was used to predict rice lodging, which was classified into two types (lodging and non-lodging), and the images were divided in a 8:2 ratio into a training set and a validation set. The CNN model was layered and trained using three optimizers (Adam, Rmsprop, and SGD). The area of rice lodging was evaluated for the three fields using the obtained data, with the exception of the training set and validation set. The images were combined to give composites images of the entire fields using Metashape, and these images were divided into 128 × 128 pixels. Lodging in the divided images was predicted using the trained CNN model, and the extent of lodging was calculated by multiplying the ratio of the total number of field images by the number of lodging images by the area of the entire field. The results for the training and validation sets showed that accuracy increased with a progression in learning and eventually reached a level greater than 0.919. The results obtained for each of the three fields showed high accuracy with respect to all optimizers, among which, Adam showed the highest accuracy (normalized root mean square error: 2.73%). On the basis of the findings of this study, it is anticipated that the area of lodged rice can be rapidly predicted using deep learning.

A Numerical Analysis to Estimate Disposal Spacing and Rock Mass Condition for High Efficiency Repository Based on Temperature Criteria of Bentonite Buffer (벤토나이트 완충재 설계 기준 온도에 따른 고효율 처분시스템 처분 간격 및 암반 조건 산정을 위한 수치해석적 연구)

  • Kim, Kwang-Il;Lee, Changsoo;Kim, Jin-Seop;Cho, Dongkeun
    • Tunnel and Underground Space
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    • v.31 no.4
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    • pp.289-308
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    • 2021
  • This study conducts coupled thermo-hydro-mechanical numerical modeling to investigate the maximum temperature and conditions for securing mechanical stability of the high-level radioactive waste repository when temperature criteria of bentonite buffer are 100℃ and 125℃, respectively. In case of temperature criterion of buffer as 100℃, the maximum temperatures at the interface between canister and buffer are calculated to be 99.4℃ and 99.8℃, respectively for a case with disposal tunnel spacing of 40 m and deposition hole spacing of 5.5 m and for the other case with disposal tunnel spacing of 30 m and deposition hole spacing of 6.5 m. In case of temperature criterion of buffer as 125℃, spacings of disposal tunnel and deposition hole could be decreased to 30 m and 4.5 m, respectively, which reduces the disposal area up to 55% compared to the disposal area of KRS+. According to analysis of mechanical stability for various disposal spacings, RMR of rock mass for KRS+ should be larger than 72.4 which belongs to good rock in RMR classification to prevent failure of rock mass. As disposal spacing is decreased, required RMR of rock mass is increased. In order to prevent failure of rock mass for a case with disposal tunnel spacing of 30 m and deposition hole spacing of 4.5 m, RMR larger than 87.3 is needed. However, mechanical stability of the repository is secured for all cases with RMR over 75 considering the enhancement of rock strength due to confining stress induced by swelling of the bentonite buffer and backfill.

Production and Fuel Properties of Wood Chips from Logging Residues by Timber Harvesting Methods (목재수확 방법에 따른 벌채부산물 목재칩의 생산 및 연료 특성)

  • Choi, Yun-Sung;Jeong, In-Seon;Cho, Min-Jae;Mun, Ho-Seong;Oh, Jae-Heun
    • Journal of Korean Society of Forest Science
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    • v.110 no.2
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    • pp.217-232
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    • 2021
  • This study calculated the productivity and cost of extraction and processing of logging residues by cut-to-length (CTL) and whole-tree (WT) harvesting methods. In addition, the comparative analysis of the characteristics of wood chip fuel to examine whether it was suitable for the fuel conditions of the energy facility. In the harvesting and processing system to produce the wood chips of logging residues the system productivity and cost of the CTL harvesting system were 1.6 Gwt/SMH and 89,865 won/Gwt, respectively. The productivity and cost of the WT harvesting system were 2.9 Gwt/SMH and 72,974 won/Gwt, respectively. The WT harvesting productivity increased 1.3times while harvesting cost decreased by 18.7% compared to the CTL harvesting system. The logging residues of wood chips were not suitable for CTL wood chips based on International Organization for Standardization (ISO 17225-4:2021) and South Korea standard (NIFoS, 2020), but the quality (A2, Second class) was improved through screening operation. The WT-unscreened wood chips conformed to NIFoS standard (second class) and did not conform to ISO but were improved through screening operation (Second class). In addition to the energy facility in plant A, all wood chips except CTL-unscreened wood chips were available through drying processing. The WT-unscreened wood chips were the lowest at 99,408 won/Gwt. Plants B, C, and D had higher moisture content than plant A, so WT-unscreened wood chips without drying processing were the lowest at 57,204 won/Gwt. Therefore, the production of logging residues should improve with operation methods that improve the quality of wood chips required for applying the variable biomass and energy facility.

Antioxidant Activity of Asteraceae Plant Seed Extracts (14종 국화과(Asteraceae) 식물 종자 추출물의 항산화 활성)

  • Kim, JunHyeok;Lee, Da Hyun;Lee, Mi Hyun;Jung, Young Ho;Park, Cho Hee;Lee, Hee Ho;Na, Chae Sun
    • Journal of Life Science
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    • v.31 no.6
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    • pp.543-549
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    • 2021
  • Approximately 10% of all angiosperms belong to the Asteraceae family. Plant species belonging to this family have traditionally been used as medicinal plants in the Korean Peninsula. We investigated the antioxidant activity of seed extracts from 14 species belonging to the Asteraceae family. Seeds with ≥ 90% percentage of filled seed and ≥ 50% final germination were used. The total phenolic content was the highest in Dendranthema zawadskii var. tenuisectum (13.5 mg of gallic acid equivalents (GAEs)/g seeds), followed by Dendranthema zawadskii var. latilobum (11.8 mg of GAEs/g seeds), and Callistephus chinensis (11.0 mg of GAEs/g seeds). The total flavonoid content was highest in C. chinensis (9.8 mg of quercetin equivalents (QEs)/g seeds), followed by D. zawadskii var. tenuisectum (7.2 mg of QEs/g seeds) and Taraxacum officinale (6.3 mg of QEs/g seeds). Our results showed that 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) scavenging activity was highest in D. zawadskii var. tenuisectum (57.4 ㎍/ml), followed by T. officinale (59.1 ㎍/ml) and D. zawadskii var. latilobum (65.0 ㎍/ml), with a half maximal inhibitory concentration (IC50) of DPPH scavenging activity. Furthermore, 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical scavenging activity was highest in C. chinensis (26.2 ㎍/ml), followed by D. zawadskii var. tenuisectum (38.4 ㎍/ml), T. officinale (40.2 ㎍/ml), with a half maximal inhibitory concentration (IC50) of ABTS scavenging activity. Based on a cluster analysis according to the antioxidant activity, the 14 species were classified into five groups, with group 4 having the highest antioxidant activity and group 0 having the lowest antioxidant activity. D. zawadskii var. latilobum, D. zawadskii var. tenuisectum, T. officinale, and C. chinensis belonging to groups 3 and 4, exhibited high phenolic content and antioxidant activity and can be considered potent plant-derived natural antioxidants.

Effects of Elevated Temperature after the Booting Stage on Physiological Characteristics and Grain Development in Wheat (밀에서 출수 후 잎의 생리적 특성 및 종실 생장에 대한 수잉기 이후 고온의 효과)

  • Song, Ki Eun;Choi, Jae Eun;Jung, Jae Gyeong;Ko, Jong Han;Lee, Kyung Do;Shim, Sang-In
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.66 no.4
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    • pp.307-317
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    • 2021
  • In recent years, global warming has led to frequent climate change-related problems, and elevated temperatures, among adverse climatic factors, represent a critical problem negatively affecting crop growth and yield. In this context, the present study examined the physiological traits of wheat plants grown under high temperatures. Specifically, the effects of elevated temperatures on seed development after heading were evaluated, and the vegetation indices of different organs were assessed using hyperspectral analysis. Among physiological traits, leaf greenness and OJIP parameters were higher in the high-temperature treatment than in the control treatment. Similarly, the leaf photosynthetic rate during seed development was higher in the high-temperature treatment than in the control treatment. Moreover, temperature by organ was higher in the high-temperature treatment than in the control treatment; consequently, the leaf transpiration rate and stomatal conductance were higher in the control treatment than in the high-temperature treatment. On all measuring dates, the weight of spikes and seeds corresponding to the sink organs was greater in the high-temperature treatment than in the control treatment. Additionally, the seed growth rate was higher in the high-temperature treatment than in the control treatment 14 days after heading, which may be attributed to the higher redistribution of photosynthates at the early stage of seed development in the former. In hyperspectral analysis, the vegetation indices related to leaf chlorophyll content and nitrogen state were higher in the high-temperature treatment than in the control treatment after heading. Our results suggest that elevated temperatures after the booting stage positively affect wheat growth and yield.

Effects of Transplanting and Direct Seeding on the Growth and Yield of Rapeseed (Brassica napus L.) during Spring Cultivation (유채 봄 재배 시 기계이식과 직파 재배시기에 따른 생육 및 수량 비교)

  • Lee, Ji-Eun;Kim, Kwang-Soo;An, Da-hee;Cha, Young-Lok
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.66 no.4
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    • pp.419-427
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    • 2021
  • In South Korea, direct seeding of rapeseed (Brassica napus L.) is difficult during spring cultivation in early March because of the low yield production associated with late flowering and poor seed quality. To compare the period of direct sowing, the present study investigated the growth characteristics of rapeseed according to planting dates. Specifically, 35 day-old seedlings were transplanted or directly sown on four different dates (late February, early March, late March, and early April) in 2020 and 2021. As the planting date was delayed, the days to flowering of rapeseed decreased. Similarly, the plant height, seed set percentage, and seed yield of rapeseed were reduced upon delay in planting. The seed yield of rapeseed through direct seeding in late February was the highest, 2.76 ton·ha-1. On all seeding dates, except for late February, the transplanted rapeseed produced a higher yields than the directly seeded rapeseed. The crude oil and oleic acid content, which is related to the quality of rapeseed, decreased with the delay in planting dates, and this decrease was greater, with the direct seeding of rapeseed depending on the sowing time. In the correlation analysis, the planting date was significantly and negatively correlated with the yield, crude oil content, and oleic acid content of the transplanted rapeseed, while the sowing date was negatively correlated with the plant height, silique size, yield, and seed quality of the directly seeded rapeseed. Finally, the effect of planting date on rapeseed growth was stronger in direct seeding than in transplanting. Therefore, during spring cultivation after late February to early March, transplanting, rather than direct seeding, in more advantageous in terms of seed quality and yield.