• Journal of the Korea Society for Simulation
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• v.4 no.1
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• pp.87-97
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• 1995

Simulation techniques are used to improve the productivity of a textile factory. A simulation model is developed for the analysis of investment for dyeing process equipment, such as dryers and bleachers. For modeling and analysis, AIM (Analyzer for Improving Manufacturing) is used. AIM is a manufacturing oriented simulation software developed by Pritsker Corp. AIM provides interactive model building and simulation, automatic animation, and powerful graphic outputs. thereby, drastically reducing modeling efforts and also enhancing communication capabilities.

• Journal of Environmental Impact Assessment
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• v.24 no.5
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• pp.487-498
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• 2015

The energy problem has occurred because of the effects of rising temperature and growing population and GDP. Prediction for the energy demand is required to respond these problems. Therefore, this study will predict heating and cooling energy consumption in residential sector to be helpful in energy demand management, particularly heating and cooling energy demand management. The AIM/end-use model was used to estimate energy consumption, and service demand was needed in the AIM/end-use model. Service demand was estimated on the basis of formula, and energy consumption was estimated using the AIM/end-use model. As a result, heating and cooling service demand tended to increase in 2050. But in energy consumption, heating decreased and cooling increased.

• Journal of Ginseng Research
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• v.44 no.6
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• pp.808-814
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• 2020

Background: Korean Red Ginseng extract (RGE) has been reported to act as an inflammasome modulator. Ginsenosides, saponin molecules of RGE, selectively inhibit activation of NLRP3 and AIM2 inflammasomes, while non-saponin molecules of RGE upregulate inflammasome components associated with the initiation of NLRP3 inflammasome activation. In this study, we investigated the effect of non-saponin components of RGE on AIM2 inflammasome activation. Methods: The role of non-saponins of RGE on AIM2 inflammasomes was tested in mouse bone marrow-derived macrophages, a human monocyte-like cell line, and a mouse animal model. Cells or mice were transfected with dsDNA or inoculated with Listeria monocytogenes to activate AIM2 inflammasomes. Several indices of inflammasome activation were examined via immunoblot or ELISA analysis. Results: The non-saponin fraction and saponin-eliminating fraction (SEF) of RGE selectively attenuated the activation of AIM2 inflammasomes, but not that of NLRP3 or NLRC4 inflammasomes. Fructose-arginine, an amino-sugar, was shown to be effective against AIM2 inflammasome activation. Conclusion: Non-saponins of RGE, such as fructose-arginine, might be effective in regulating infectious and autoimmune diseases resulting from AIM2 inflammasome activation.

• IE interfaces
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• v.9 no.2
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• pp.191-202
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• 1996

A variety of approaches on performance evaluation modeling have appeared in the technical literature for flexible manufacturing systems(FMS) which can be evaluated only through computer simulation. This study represents a comparative approach for FMS performance evaluation modeling based on reliability, availability and maintainability, and life cycle cost. The methodology proposed in this research includes the following three-step generative approaches. First, a static model to find the initial system configuration is considered under the assumption that the system availability is given as one (failure and maintenance are not considered), and in second step, a stochastic simulation is proposed to serve as a performance evaluation model for FMS with stochastic failure and repair time. In the last step, we developed a simulation modeling using a simulator, FACTOR/AIM to consider a variety of performance factors and dynamic behavior of FMS. Also the applicability and validity of the proposed approaches has been tested and compared through the results of a sample problem using computer programs and procedures developed in each step.

• Steel and Composite Structures
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• v.18 no.2
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• pp.325-344
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• 2015

Experimental tests on cellular beams with sinusoidal openings showed two main failure modes around the openings. They concern the formation of four plastic hinges and the local instability of the sinusoidal part of the opening. In parallel, numerical analysis of the sinusoidal part of the opening revealed the existence of an elastic rotational restraint between the intermediate web-post and the adjacent opening panel. The aim of the present study is to present an approach to quantify this rotational restraint. Through the response surface method, a mathematical model is proposed. It shows a great ability to predict the rotational restraint value as a function of the geometrical parameters of the opening. This model can be used to perform an extensive study with various geometrical configurations of beams with the aim to develop a reliable and realistic analytical model predicting the resistance of the sinusoidal openings.

• International journal of advanced smart convergence
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• v.13 no.1
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• pp.57-68
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• 2024

In this paper, we are interested in how creator economy startups allowing creators to make money from doing that they love. So, we look at European creator economy startups among Web3.0 business model landscape surveyed in 2022, because the US is home of Web2.0 giant platforms like YouTube. Totally seventeen European startups are investigated, and the theoretical logic is the disruptive innovation. We firstly review the survey published in 2022 and utilize the theory of the disruptive innovation to design the research framework including questions with each type of the disruptive innovation. In this paper, we firstly show, Kalao and Gem as NFT ecosystem platforms aim at service convenience. Secondly, Talkbase, Passionfroot, Bildr, Customuse, and Earnr aim at providing creator tools for under-skilled customers. Lastly, when it comes direct monetization with a decentralized business model, CrowdPad, Admix, GOALS, Realm, Dropstar, Pianity, Sonomo, Stage11, Miiji, and ReadyPlayerMe are representative. Despite the relatively small data size, the results are meaningful as they contribute to a more profound comprehension of the Web3.0 business models and offer guidance for future research directions.

• Journal of Korean Neurosurgical Society
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• v.66 no.2
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• pp.121-132
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• 2023

Objective : The parafascicular nucleus (PF) plays important roles in controlling the basal ganglia. It is not well known whether the PF affects the development of abnormal involuntary movements (AIMs). This study was aimed to find a role of the PF in development of AIMs using optogenetic methods in an animal model. Methods : Fourteen rats were underwent stereotactic operation, in which they were injected with an adeno-associated virus with channelrhodopsin (AAV2-hSyn-ChR2-mCherry) to the lateral one third of the PF. Behavior test was performed with and without optical stimulation 14 days after the injection of the virus. AIM of rat was examined using AIM score. After the behavior test, rat's brain was carefully extracted and the section was examined using a fluorescence microscope to confirm transfection of the PF. Results : Of the 14 rats, seven rats displayed evident involuntary abnormal movements. AIM scores were increased significantly after the stimulation compared to those at baseline. In rats with AIMs, mCherry expression was prominent in the PF, while the rats without AIM lacked with the mCherry expression. Conclusion : AIMs could be reversibly induced by stimulating the PF through an optogenetic method.

• The Korean Nurse
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• v.21 no.3 s.116
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• pp.49-58
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• 1982

The aim of this study, is twofold to investigate essential concept of Sister C. Roy''s Adaptation Model, and to make a case-study of nursing care about an Acute Myelaemia patient through the frame of this model. Seeing a human being as a bio-psycho-sociai

• Journal of Korean Institute of Industrial Engineers
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• v.27 no.1
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• pp.95-102
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• 2001

The design of automobile body assembly line is one of essential parts for improving the process performance. The major objective of this research is to develop a performance evaluation model for automobile assembly line using a closed queueing network(CQN) and simulation method. In this study we used a two-step approach to compute the performance of the assembly line : first, we used CQN model considering assembly line equipments and the line operating time under the assumption of no failure, and second we used a well-known simulator FACTOR/AIM. Finally we implemented this model on a K automobile company and we have shown the sample results of automobile body assembly line.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.28 no.3
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• pp.154-159
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• 2015

In this paper, we propose a numerical method to model temperature dependent threshold voltage shift observed in metal oxide thin-film transistors (TFTs). The proposed model is then implemented in AIM-SPICE circuit simulation tool. The proposed method consists of modeling the well-known stretched-exponential time dependent threshold voltage shift and their temperature dependent coefficients. The outputs from AIM-SPICE tool and the stretched-exponential model at different temperatures in the literature are compared and they show a good agreement. Since metal oxide TFTs are the promising candidate for flat panel displays, the proposed method will be a good stepping stone to help enhance reliability of fast-evolving display circuits.