• Journal of the Korea Society of Computer and Information
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• v.7 no.3
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• pp.80-91
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• 2002

A general goal of the AT%(Asynchronous Transfer Mode) network is to support connect across various network. On ATM networks, ABR services are provided using the remained ban after allocation CBR and VBR traffic. Realtime services such as transmitting audio or video data may be provided using CBR ado VBR which have a constrained transmission delay, but in these cases, the communications bandwidth may be wasted. In this paper a simulation has been performed to compare and evaluate the performance between the ERICA(Explicit Rate Indicate Avoidance) and EPRCA(Enhanced Proportional Rate Control Algorithm) switches which use Explicit Rate switch algorithm for ABR switch. The variation of the ACR at the source end system, the queue length, the utilization rate of the link bandwidth and the share fairness at the transient and steady states are used as the evaluation criteria for the simulation. As a result of simulation, ERICA algorithm switch was ten times long compared to ERPCA switch to achieve assigned fair share. so EPRCA switch is superior to ERICA about load response. For Fair share and stability, ERICA switch is excellent to EPRCA switch.

• The Journal of Internal Korean Medicine
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• v.42 no.2
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• pp.215-223
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• 2021

Objectives: The purpose of this study is to report the effects of Korean medicine treatment, including Onkyung-tang, on fibromyalgia. Methods: The patient was treated with herbal medicine, acupuncture, pharmacopuncture, and chuna manual therapy for 13 days. To evaluate the improvements, we used a numeric rating scale (NRS), the American College of Rheumatology Preliminary Diagnostic Criteria (ACR), the neck disability index (NDI), and the Oswestry disability index (ODI). Results: After treatment, the scores for the NRS, ACR, NDI, and ODI all decreased compared with baseline. Conclusion: This study suggests that Korean medicine treatment that includes Onkyung-tang can be effective in reducing pain and increasing ability to function in patients with fibromyalgia.

• Korean Journal of Radiology
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• v.25 no.2
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• pp.134-145
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• 2024

Abnormalities on breast ultrasound (US) images which do not meet the criteria for masses are referred to as nonmass lesions. These features and outcomes have been investigated in several studies conducted by Asian researchers. However, the term "nonmass" is not included in the American College of Radiology (ACR) Breast Imaging Reporting and Data System (BI-RADS) 5th edition for US. According to the Japan Association of Breast and Thyroid Sonology guidelines, breast lesions are divided into mass and nonmass. US findings of nonmass abnormalities are classified into five subtypes: abnormalities of the ducts, hypoechoic areas in the mammary glands, architectural distortion, multiple small cysts, and echogenic foci without a hypoechoic area. These findings can be benign or malignant; however, focal or segmental distributions and presence of calcifications suggest malignancy. Intraductal, invasive ductal, and lobular carcinomas can present as nonmass abnormalities. For the nonmass concept to be included in the next BI-RADS and be widely accepted in clinical practice, standardized terminologies, an interpretation algorithm, and outcome-based evidence are required for both screening and diagnostic US.

• The Korean journal of internal medicine
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• v.33 no.6
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• pp.1224-1233
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• 2018

Background/Aims: The objective of this study was to determine the efficacy and safety of add-on therapy with certolizumab pegol (CZP) in active rheumatoid arthritis (RA) patients of a single ethnicity. Methods: In this 24-week, phase 3, randomized, double-blind, placebo-controlled trial, eligible patients (n = 127) were randomized 2:1 to subcutaneous CZP + methotrexate (MTX; 400 mg at week 0, 2, and 4 followed by 200 mg every 2 weeks) or placebo + MTX. Results: At week 24, the American College of Rheumatology criteria for 20% (ACR20) response rate was significantly greater with CZP + MTX than with placebo (66.7% vs. 27.5%, p < 0.001). Differences in ACR20 response rates for CZP vs. placebo were significant from week 1 (p < 0.05) and remained significant through week 24. The CZP group reported significant improvement in physical function and disability compared to the placebo group (p < 0.001) at week 24, as assessed by Korean Health Assessment Questionnaire-Disability Index (KHAQ-DI). Post hoc analysis indicated that the proportion of patients who had ACR70 responses, Disease Activity Score 28 (DAS28) low disease activity, and DAS28 remission at week 24 was greater in CZP + MTX-treated patients who achieved a decrease in DAS28 ${\geq}1.2$ (43.8%) at week 4 than in nonresponders. Among 18 (22.2%) and 14 patients (35.0%) in CZP and placebo groups who had latent tuberculosis (TB), none developed active TB. Most adverse events were mild or moderate. Conclusions: CZP treatment combined with MTX in active RA patients with moderate to severe disease activity and an inadequate response to MTX resulted in rapid onset of efficacy, which is associated with better clinical outcome at week 24 and has an acceptable safety profile, especially in an intermediate TB-burden population.

• Journal of Korean Academy of Nursing
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• v.35 no.1
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• pp.87-94
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• 2005

Purpose: The purpose of this research was to provide basic data in the control of depression found in patients with fibromyalgia by analysing the main factors that affect them. Method: The subjects were 207 out-patients in three university medical centers diagnosed with fibromyalgia according to the conditions by American College of Rheumatology (1990). Depression was measured by the CES-D Scale. Dependant variables, such as stress and anxiety were measured by the VAS Scale and physical activity was measured using 10(4-point-scale) questions developed by the researcher. The number of tender points was converted to scores based on the criteria of the ACR(1990) and of Yunus. Self-efficacy was measured by the Self-Efficacy Scale developed by Lorig et al. (1989) for arthritis patients. Result: The main factors that affect depression of patients with fibromyalgia were self-efficacy, anxiety, physical activity, tender points fatigue, and family support, which explained 49% of the depression. Conclusion: It has been confirmed that the regression equation model of this research may serve as a predictor of depression in patients with fibromyalgia.

• Journal of Sasang Constitutional Medicine
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• v.32 no.4
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• pp.129-140
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• 2020

Objectives This study aimed to report significant improvement of fibromyalgia patient who was diagnosed with 'Taeeumin esophagus-cold lung-dry symptomatology' based on Sasang Constitutional Medicine. Methods The patient was treated with herbal medicine. To evaluate the results of this treatment, the patient assessed pain of Fibromyalgia by using the Numeral Rating Scale (NRS) and American College of Rheumatology Preliminary Diagnostic Criteria (ACR, 2010). Results After 64 days of treatment, the NRS of pain reduced from 6 to 2. There was no difference before and after treatment with Widespread Pain Index 7, but Symptom Severity scale score decreased from 8 to 4. Headache, dizziness, and chilling symptoms were also improved. Conclusions The patient showed a significant improvement of Fibromyalgia and accessory symptoms without any side effects, who was treated with herbal medicine.

• Journal of Acupuncture Research
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• v.21 no.3
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• pp.265-282
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• 2004

Objective : The aim of this study was to review systemically clinical trials on the effectiveness and safety of herbal medicines in the treatment of osteoarthritis. Methods : Computerized literature searches were carried out on seven electronic databases, and hand-searching on some chinese medical journals in library of Kyung Hee Medical Center. Trial data were extracted in a standardized, predefined manner and assessed independently. Results : 1. Thirty reports of clinical trials and two reports of meta-analyses concerning herbal medicine were collected and reviewed. Among these reports three medical herbs were applied as topical medicine and others as internal medicine. 2. The western studies established NSAIDs or placebo as their control group. Five chinese reports established formulated herb pill(Ruanshnagshenjin pill) as their control group and Six did not establish a control group at all. 3. ACR was the most highly used diagnostic criteria in the western studies while the Chinese used their official criteria established by their government or the criteria of their text books. 4. 20 reports chose the Lequesne functional index, SHAQ, WOMAC OA index, AIMS, and their own unique scoring system as the criteria of analysing the effect. Others chose clinical symptoms, articular functions, and lab finding as their criteria. 5. 7 single herbs and 19 formulated herbs were studied. Among the formulated herbs, Achyranthes japonica was studied in 10 of the studies and Angelica gigantis Radix in 8, making them the most often studied herbs among the studies.

• Journal of Acupuncture Research
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• v.26 no.6
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• pp.77-83
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• 2009

Objectives : The aim of this study was to evaluate the usefulness of ultrasonography of knee osteoarthritis. Methods : 124 osteoarthritis patients classified by the American College of Rheumatology (ACR) clinical criteria were included in the study. Simple X-ray and ultrasonography examination (effusion, osteophyte, articular cartilage, Backer's cyst) of knee in pain were performed. Also VAS, KWOMAC score were checked. Results : X-ray showed abnormal findings in 112 patients, but ultrasonography showed abnormal findings in all 124 patients. 12 Patients with unremarkable knee X-ray showed effusion and osteophyte in the ultrasonography. Effusion was discovered only in 18 cases of X-ray and 62 cases of ultrasonography. Group with effusion showed higher VAS mean figure but couldn't retrieve significant difference. KWOMAC showed no significant difference. Conclusions : Osteoarthritis patients with no abnormality in X-ray diagnosed abnormal findings through sonograph, which manifest that sonograph can be utilized for differential diagnosis especially sensitive on the problem of effusion.

• The Korean Journal of Physiology and Pharmacology
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• v.13 no.1
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• pp.33-37
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• 2009

Anti-inflammatory factor(AIF) is a water soluble extract of three herbs, Panax notoginseng(Burk.) F. H. Chen, Rehmannia glutinosa Libosch and Eleutherococcus senticosus. The present study aimed to investigate the safety and efficacy of herb extracts, AIF, on Korean knee osteoarthritis patients for six weeks. Fifty seven patients with knee osteoarthritis, ranging from 43 to 73 years of age, who fulfilled the "American College of Rheumatology"(ACR) classification of idiopathic osteoarthritis of knee and radiographic criteria were randomly selected and enrolled for the study. After initial screening and resting period, two capsules each of AIF(Each capsule contains; 400 mg) and similar identical placebo were administered twice a day to both groups. Pain intensity at second, fourth, and sixth weeks of study as well as one week after discontinuation of drugs was assessed by using 100 mm visual analogue scale(VAS). Changes in the Korean version of the Western Ontario and McMaster Universities(K-WOMAC) index score were compared at the initiation and completion of the study. VAS assessed by patients were significantly reduced(at visit 2; $54.64{\pm}14.72$, at visit 4, $37.32{\pm}16.58$, p<0.001) after AIF administration. Results showed an improvement in the physical function of K-WOMAC scale which was significantly higher(p=0.013) in AIF than placebo group, and decreases of total K-WOMAC score were also significantly higher(p=0.030) in AIF groups than placebo group. No serious adverse effect was observed, and there was no difference in incidence of adverse effect between AIF and placebo groups. In this population of Korean patients with knee osteoarthritis, AIF was found to be safe, tolerable and effective for symptomatic improvement of pain and physical function.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.8
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• pp.3229-3232
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• 2015

Background: Triple-negative breast cancer (TNBC) is known to be associated with aggressive biologic features and a poor clinical outcome. Therefore, early detection of TNBC without missed diagnosis is a requirement to improve prognosis. Preoperative ultrasound features of TNBC may potentially assist in early diagnosis as characteristics of disease. Purpose: To retrospectively evaluate the sonographic features of TNBC compared to ER (+) cancers which include HER(-) and HER2 (+), and HER2 (+) cancers which are ER (-). Materials and Methods: From June 2012 through June 2014, sonographic features of 321 surgically confirmed ER (+) cancers (n=214), HER2 (+) cancers (n=66), and TNBC (n=41) were retrospectively reviewed by two ultrasound specialists in consensus. The preoperative ultrasound and clinicopathological features were compared between the three subtypes. In addition, all cases were analyzed using morphologic criteria of the ACR BI-RADS lexicon. Results: Ultrasonographically, TNBC presented as microlobulated nodules without microcalcification (p=0.034). A lower incidence of ductal carcinoma in situ (p<0.001), invasive tumor size that is>2 cm (p=0.011) and BI-RADS category 4 (p<0.001) were significantly associated with TNBC. With regard to morphologic features of 41 TNBC cases, ultrasonographically were most likely to be masses with irregular (70.7%) microlobulated shape (48.8%), be circumscribed (17.1%) or have indistinct margins (17.1%) and parallel orientation (68.9%). Especially TNBC microlobulated mass margins were more more frequent than with ER (+) (2.0%) and HER2 (+) (4.8%) cancers. Conclusions: TNBC have specific characteristic in sonograms. Ultrasonography may be useful to avoid missed diagnosis and false-negative cases of TNBC.