• 한국의류학회지
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• 제47권4호
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• pp.760-777
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• 2023

Fashion brands seek guidelines for effective green advertising messages, considering benefit appeals, brand types, and construal level. However, few studies have explored their simultaneous interplay. Thus, the present study conducted an experiment with a 2X2X2 between-subjects design to investigate how brand type and construal level moderate the mediating role of ad-brand congruency between benefit appeals and purchase intention. A total of 245 Millennials and Generation Z participants completed an online survey, and the data were analyzed using SPSS. A significant three-way interaction was revealed. Low-construal-level messages with concrete content showed disparities between aspirational and accessible brands concerning other-benefit appeals: Accessible brands utilizing other-benefit appeals demonstrated higher ad-brand congruency, while aspirational brands had lower ad-brand congruency. Furthermore, within aspirational brands, self-benefit appeals resulted in higher ad-brand congruency than other-benefit appeals. Finally, a moderated mediating effect was discovered, indicating that brand types and construal level moderated the mediating effect of ad-brand congruency between benefit appeals and purchase intention. The mediating effect was prominent in the context of self-benefit appeals, aspirational brands, and low-construal-level messages. This study highlights the intricate dynamics of the three factors in green advertising, providing valuable insights for crafting more targeted green advertisements.

• 천문학회보
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• 제42권2호
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• pp.55.5-56
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• 2017

Galaxy dynamics probes weak gravity at accelerations below the de Sitter scale of acceleration adS = cH, where c is the velocity of light and H is the Hubble parameter. Low and high redshift galaxies hereby offer a novel probe of weak gravity in an evolving cosmology, satisfying H(z) = H0(1 + A(6z + 12z^2 +12z^3+ 6z^4+ (6/5)z^5)/(1 + z) with baryonic matter content A sans tension to H0 in surveys of the Local Universe. Galaxy rotation curves show anomalous galaxy dynamics in weak gravity aN < adS across a transition radius r beyond about 5 kpc for galaxy mass of 1e11 solar mass. where aN is the Newtonian acceleration based on baryonic matter content. We identify this behavior with a holographic origin of inertia from entanglement entropy, that introduces a C0 onset across aN=adS with asymptotic behavior described by a Milgrom parameter satisfying a0=omega/(2pi), where omega=sqrt(1-q)H is a fundamental eigenfrequency of the cosmological horizon. Extending an earlier confrontation with data covering 0.003 < aN/adS < 1 at redshift z about zero in Lellie et al. (2016), the modest anomalous behavior in the Genzel et al. sample at redshifts 0.854 < z <2.282 is found to be mostly due to clustering 0.36 < aN/adS < 1 close to the C0 onset to weak gravity and an increase of up to 65% in a0.

• 한국물환경학회지
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• 제32권3호
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• pp.297-302
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• 2016

Microbial electrochemical technology (MET) has recently been studied to improve the efficiency of a traditional anaerobic digestion (AD). The purpose of this study was to investigate the impact of MET in the system when MET was combined with traditional AD (i.e., AD-MET). Electrodes used in the MET were Cu coated graphite electrodes. They were supplied with a voltage of 0.3 V. AD started to generate methane in 80 days. But AD-MET started to generate methane from the initial operation after the system started. It was observed that AD-MET reached steady state faster and produced higher methane yield than AD. During the steady state, the average daily methane productions in AD and AD-MET were 2.3L/d and 4.9L/d, respectively. Methane yields were 0.07-CH₄/g‧CODre in AD and 0.25L-CH₄/g‧CODre in AD-MET. In AD-MET, the production rates of total volatile fatty acids (TVFAs) and soluble chemical oxygen demand (SCOD) were 0.12 mg TVFAs/mg VS‧d and 0.35 mg SCOD/mg VS‧d, respectively. They were significantly (p < 0.05) higher than those in AD. However, the concentrations of residual TVFAs in both systems were not significantly (p > 0.05) different from each other, confirming that methane conversion in AD-MET was greater than that in AD.

• Journal of Information Technology Applications and Management
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• 제10권2호
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• pp.61-71
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• 2003

Ad-hoc networks are characterized by multi-hop wireless links, frequently changing network topology and the need for efficient dynamic routing protocols. In an Ad-hoc network, each host assumes the role of a router and relays packets toward final destinations Because a packet is broadcast to all neighboring nodes, the optimality criteria of wireless network routing is different from that of wired network routing. tn this paper 1 point out the more important cost factor than the number of links in the Ad-hoc network. A class routing protocols called on-demand protocols has recently found attention because of their low routing overhead since it performs a blind flooding to look for a path. In this paper, 1 propose the method which reduces overhead by using the information of neighboring nodes and doing a selective flooding. Simulation results demonstrate better reduction of routing overheads with this scheme.

• 한국정보통신학회논문지
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• 제8권4호
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• pp.826-832
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• 2004

본 논문에서는 VLSI의 내장 회로로 사용하기에 적합한 CMOS 8 비트 폴딩-인터폴레이팅 AD 변환기를 설계하였다. 폴딩 AD 변환기의 비선형성을 개선하기 위하여 입력신호의 폴딩-인터폴레이팅에 의한 신호처리가 차례로 2 번 반복되는 2 단 구조를 사용하였다. 이 구조에서는 2 번째 폴딩 회로로서 트랜지스터 차동쌍을 이용한다. 2 단 폴딩 ADC는 디지틸 출력을 얻기 위한 전압비교기와 저항의 개수를 현저히 줄일 수 있으므로 칩 면적, 소비전력, 동작속도 둥에서 많은 장점을 제공한다. 설계공정은 0.25$\mu$m double-poly 2 metal n-well CMOS 공정을 사용하였다. 모의실험결과 2.5V 전원 전압을 인가하고 250MHz의 샘플링 주파수에서 45mW의 전력을 소비하였으며 INL과 DNL은 각 각 $\pm$0.2LSB, SNDR은 10MHz 입력신호에서 45dB로 측정되었다.

• 한국환경보건학회지
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• 제38권6호
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• pp.472-481
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• 2012

Objectives: This study aims to investigate the AD (allergic diseases: asthma, allergic rhinitis and atopic dermatitis) prevalence among elementary schoolchildren in an industrial city, Ulsan, and identify major environmental risk factors associated with AD prevalence. Methods: Data on the physician-diagnosed prevalence over the past 12 months and potential risk factors of AD were collected through a questionnaire from a 2009-2010 survey of 4,067 schoolchildren living in different urban environments. The logistic regression analysis was performed to assess differences in AD prevalence among the areas and to determine which environmental factors impacted AD. Results: Our survey results showed that the AD prevalence rate ranged between 26.2% and 35.9%. Children living in polluted areas (near industrial and central urban areas) had about a 10% higher prevalence of AD than did those living in coastal or suburban residences. The Chi-Square test demonstrated that this local difference was statistically significant before and after adjustment of major confounders such as parental AD history and parental education. The results of the logistic regression analysis showed a statistically significant association between several environmental factors (ventilation in winter, odor conditions and exposure to traffic smoke, and outdoor $PM_{10}/O_3$ pollution) and the prevalence of AD found by multivariate model after adjusting confounders. Conclusion: These results suggest that local differences in AD prevalence are significantly associated with outdoor environmental factors. Although there are likely to be other risk factors for AD, living in a polluted area and exposure to high levels of air pollutants can contribute to an increased risk of childhood AD.

• Biomolecules & Therapeutics
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• 제28권6호
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• pp.542-548
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• 2020

Naturally derived diosmetin and its glycoside diosmin are known to be effective in treating inflammatory disease. This study was performed to determine whether diosmin and diosmetin have the effect of improving atopic dermatitis in a 2,4-dinitrochlorobenzen (DNCB)-induced atopic dermatitis (AD) model. DNCB was used to establish AD model in hairless mice. Skin moisture, serum immunoglobulin E (IgE), interleukin 4 (IL-4), and histological analysis were performed to measure the effectiveness of diosmin and diosmetine to improve AD. IL-4 levels were also measured in RBL-2H3 cells. Administration of diosmetin or diosmin orally inhibited the progress of DNCB-induced AD-like lesions in murine models by inhibiting transdermal water loss (TEWL) and increasing skin hydration. Diosmetin or diosmin treatment also reduced IgE and IL-4 levels in AD-induced hairless mouse serum samples. However, in the in vitro assay, only diosmetin, not diosmin, reduced the expression level of IL-4 mRNA in RBL-2H3 cells. Diosmin and diosmetine alleviated the altered epidermal thickness and immune cell infiltration in AD. Diosmin is considered effective in the cure of AD and skin inflammatory diseases by being converted into diosmetin in the body by pharmacokinetic metabolism. Thus, oral administration of diosmetin and diosmin might be a useful agent for the treatment of AD and cutaneous inflammatory diseases.

• Nutrition Research and Practice
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• 제16권5호
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• pp.577-588
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• 2022

BACKGROUND/OBJECTIVES: Poorly regulated inflammation is believed to be the most predominant factor that can result in a wide scope of diseases including atopic dermatitis (AD). Despite many studies on the effect of pear pomace in obesity-related disorders including dysregulated gut microbiota, the protective effect of pear pomace in AD is still unknown. This study aimed to evaluate the effect of pear pomace ethanol extract (PPE) on AD by inhibiting inflammation. MATERIALS/METHODS: In the in vivo experiment, 2, 4-dinitrochlorobenzene (DNCB) was applied to NC/Nga mice to induce AD-like skin lesions. After the induction, PPE was administered daily by oral gavage for 4 weeks. The clinical severity score, serum IgE levels, spleen weight, histological changes in dorsal skin, and inflammation-related proteins were measured. In the cell study, RAW 264.7 cells were pretreated with PPE before stimulation with lipopolysaccharide (LPS). Nitrite oxide (NO) production and nuclear factor kappa B (NF-𝛋B) protein expression were detected. RESULTS: Compared to the AD control (AD-C) group, IgE levels were dramatically decreased via PPE treatment. PPE significantly reduced scratching behavior, improved skin symptoms, and decreased ear thickness compared to the AD-C group. In addition, PPE inhibited the DNCB-induced expression of inducible nitrite oxide synthase (iNOS), the receptor for advanced glycation end products, extracellular signal-regulated kinase (ERK) 1/2, and NF-𝛋B. PPE inhibited the LPS-induced overproduction of NO and the enhanced expression of iNOS and cyclooxygenase-2. Moreover, the phosphorylation of ERK1/2 and NF-𝛋B in RAW 264.7 cells was suppressed by PPE. CONCLUSIONS: These results suggest that PPE could be explored as a therapeutic agent to prevent AD.

• 한국약용작물학회:학술대회논문집
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• 한국약용작물학회 2011년도 추계학술발표회
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• pp.31-45
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• 2011

The amyloid ${\beta}$-peptide ($A{\beta}$), which originates from the proteolytic cleavage of amyloid precursor protein (APP), plays a central role in the pathogenesis of Alzheimer's disease (AD). Mounting evidence indicates that different species of $A{\beta}$, such as $A{\beta}$ oligomers and fibrils, may contribute to AD pathogenesis via distinct mechanisms at different stages of the disease. Importantly, elevation and accumulation of soluble $A{\beta}$ oligomers closely correlate with cognitive decline and/or disease progression in animal models of AD. In agreement with these studies, oligomers of $A{\beta}$ have been shown to directly affect synaptic plasticity, a neuronal process that is known to be essential for memory formation. Our previous studies showed that $A{\beta}$ induces the breakdown of phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2), a phospholipid that regulates key aspects of neuronal function. PI(4,5)P2 breakdown was found to be a key step toward synaptic and memory dysfunction in a mouse model of AD. To this end, we seek to identify small molecules that could elevate the levels of PI(4,5)P2 and subsequently block $A{\beta}$ oligomer-induced breakdown of PI(4,5)P2 and synaptic dysfunction.. We found that (20S)Rg3, an active triterpene glycoside from heat-processed ginseng, serves as an agonist for phosphatidylinositol 4-kinase IIalpha (PI4KIIalpha), which is a lipid kinase that mediates a rate-limiting step in PI(4,5)P2 synthesis. Consequently, (20S)Rg3 stimulates PI(4,5)P2 synthesis by directly stimulating the activity of PI4KIIalpha. Interestingly, treatment of a mouse model of AD with (20S)Rg3 leads to reversal of memory deficits. Our data suggest that the PI(4,5)P2-promoting effects of (20S)Rg3 may help mitigate the cognitive symptoms associated with AD.

• 디지털산업정보학회논문지
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• 제18권2호
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• pp.9-16
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• 2022

The nodes constituting the vehicle ad hoc network (VANET) are vehicles moving along the road and road side units (RSUs) installed around the road. The vehicle ad hoc network is used to collect the status, speed, and location information of vehicles driving on the road, and to communicate with vehicles, vehicles, and RSUs. Today, as the number of vehicles continues to increase, urban roads are suffering from traffic jams, which cause various problems such as time, fuel, and the environment. In this paper, we propose a method to solve traffic congestion problems on urban roads and demonstrate that the method can be applied to solve traffic congestion problems through performance evaluation using two typical protocols of vehicle ad hoc networks, AODV and GPSR. The performance evaluation used ns-2 simulator, and the average number of traffic jams and the waiting time due to the average traffic congestion were measured. Through this, we demonstrate that the vehicle ad hoc-based traffic congestion management technique proposed in this paper can be applied to urban roads in smart cities.