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Preoperative Staging in Non-Small Cell Lung Cancer without Lymphadenopathy on Computed Tomogram (흉부 전산화 단층촬영상 임파절종대가 없는 비소세포암 환자에 있어서 술전 병기판정)

  • Cha, Seung-Ick;Kim, Chang-Ho;Park, Jae-Yong;Jung, Tae-Hoon;Chang, Bong-Hyun;Kang, Duk-Sik
    • Tuberculosis and Respiratory Diseases
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    • v.41 no.6
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    • pp.616-623
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    • 1994
  • Objectives: Careful evaluation about mediastinal involvement is important in the management of patients with non-small cell lung cancer. Invasive staging procedure such as mediastinoscopy is advocated because of the unreliability of noninvasive staging methods such as CT, MRI. We compared differences between pre- and postoperative staging in non-small cell lung cancer without lymphadenopathy on CT scan and investigated the methods for more accurate preoperative staging. Methods & Results: 1) Records of a total of 41 patients with preoperative $T_{1-3}N_0M_0$ non-small cell lung cancer were reviewed and the histologic types of tumors were squamous cell carcinoma in 32 cases, adenocarcinoma in 6 cases and large cell carcinoma in 3 cases. Twenty-four cases were central lesions and seventeen cases were peripheral lesions. 2) Among the 32 cases with preoperative $T_2$, 2 cases were identified postoperatively as $T_3$ with invasion of chest wall and among 6 cases with preoperative $T_3$, 1 case was identified postoperatively as $T_4$ with invasion of aorta and pulmonary arteries. 3) After the operation of 35 cases with $T_{1-2}$, 5 cases were $N_1$ and 3 cases were $N_2$ postoperatively. After the operation of 6 cases with $T_3$, 2 cases were $N_1$ and 3 cases were $N_2$ postoperatively. Preoperative $T_3$ showed more intrathoracic lymph node metastases and higher $N_2/N_1$ involvement ratio than preoperative $T_{1-2}$. 4) Complete surgical resections were done in 34 out of 41 cases. Incomplete resection were done in all postoperative $N_2$ tumors. Conclusion: Invasive staging procedures such as mediastinoscopy should be considered in the case of preoperative $T_3$ non-small cell lung cancer even though mediastinal lymphadenopathy is not recognized on the CT scan of the chest.

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OSCILLATION AND NONOSCILLATION THEOREMS FOR NONLINEAR DIFFERENTIAL EQUATIONS OF SECOND ORDER

  • Kim, Rak-Joong;Kim, Dong-Il
    • Journal of the Korean Mathematical Society
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    • v.44 no.6
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    • pp.1453-1467
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    • 2007
  • By means of a Riccati transform some oscillation or nonoscillation criteria are established for nonlinear differential equations of second order $$(E_1)\;[p(t)|x#(t)|^{\alpha}sgn\;x#(t)]#+q(t)|x(\tau(t)|^{\alpha}sgn\;x(\tau(t))=0$$. $$(E_2),\;(E_3)\;and\;(E_4)\;where\;0<{\alpha}$$ and $${\tau}(t){\leq}t,\;{\tau}#(t)>0,\;{\tau}(t){\rightarrow}{\infty}\;as\;t{\rightarrow}{\infty}$$. In this paper we improve some previous results.

Effects of Aluminum Sulfate Addition on Six-Week-Old Broiler Performance and Nitrogen Contents in Litter at the Sixth Week (Aluminum Sulfate 처리가 6주령 육계생산 능력 및 깔짚 내의 질소 함량에 미치는 영향)

  • 최인학;남기홍
    • Korean Journal of Poultry Science
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    • v.29 no.4
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    • pp.265-270
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    • 2002
  • This study was conducted to determine the effect of aluminum sulfate[Al$_2$(S0$_4$)$_3$$.$14H$_2$O], commonly referred to as ALUM, addition to broiler litter on 3 and 6 week old broiler performance and the nitrogen content of the litter at 6 weeks of age. The two treatment groups were 134 identical diets with the same protein levels, but one group(T$_1$) had ALUM added as a top dressing to the litter at a rate of 200 g ALUM / kg of rice bran, while T$_2$ did not have ALUM added to the litter. Feed consumption for T$_1$ was higher in the 22 to 42 day-old and 0 to 42 day-old periods (P<0.05). Body weight in T$_1$ was also higher in the 0 to 42 day -old period (P<0.0l). There was no difference, however, in the feed : gain ratio between T$_1$ and T$_2$ During the first 5 weeks, T$_1$ had significantly less(P<0.05 or 0.01) ammonia emission from the litter than T$_2$ but at 6 weeks there was no difference in ammonia concentration between the two groups. At 6 weeks, T$_1$ had a lower litter pH than Ta (P<0.05) and total Kjeldahl nitrogen(TKN) was higher far T$_1$ than T$_2$ (P<0.05). However,71 did not show any difference from T$_2$ in the content of NH4-N and NO3-N. In summary, the addition of ALUM to broiler litter improved broiler performance at 6 weeks, while increasing nitrogen content from the litter used as the nitrogen fertilizer although ammonia emission was increased in T$_1$ at 6 weeks.

Improvement of Mechanical Properities in Al-Cu-Li-Ag-Mg-Zr Alloys by Thermomechanical Treatement (가공열처리에 의한 고강도 Al-Cu-Li-Ag-Mg-Zr 합금의 기계적 성질 개선)

  • Yu, C.H.;Namkung, I.;Lee, O.Y.;Kim, D.K.
    • Journal of the Korean Society for Heat Treatment
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    • v.5 no.2
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    • pp.103-110
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    • 1992
  • This study is aimed to investigate the effect of various thermomechanical treatments($T_6$, $T_8$ and ITMT) on the microstructure and mechanical properties of an Al-Cu-Li-Ag-Mg-Zr alloy (Weldalite 049) which has been known to strong natural aging response, good weldablity and high strength in $T_6$ sand $T_8$ temper. This experiment was performed by means of differential scaning calorimetry, tensile test, optical and transmission electron microscopy. The tensile strength in the peak aged condition shows 620, 650 MPa in $T_6$ and $T_8$(40% cold work), respectively. Also, The tensile strength is increased with cold working in $T_8$ but decreased at 60% cold working. However, the tensile strength of the intermediate thermomechanical treated speciman(ITMT) is lower than that of $T_6$ temper about 20% but the elongation is higher than two times. It might be predicted that the ITMT is effective processing to improve the toughness of this alloy. In $T_6$, $T_8$ and ITMT, the major strengthening phase is $T_1(Al_2CuLi)$ phases. and the fine $T_1$ phase which are homogeneously precipited in matrix was observed much more in $T_8$ than $T_6$ and ITMT.

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Study on brewing of sweet potato starch (고구마 전분질원료를 이용한 주류제조에 관한 연구)

  • 정기택;유대식
    • Korean Journal of Microbiology
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    • v.9 no.3
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    • pp.103-120
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    • 1971
  • We have been studied on brewing sweet starch. We obtained the results as follows ; 1) 5 strains, T-T-2, T-T-4, T-K-2, T-T-18, T-T-1, were the most available in view of fermentative power by capacity of $CO_2$. 2) 5 strains, T-T-4, T-T-2, T-T-1, T-T-3, T-K-2, produced capacity of alcohol more than 5.78%. 3) 6 strains, T-T-2, T-K-2, T-T-4, T-S-2, T-I-3, T-I-1, are available not only taste and flavour, but productive power of alcohol in sweet potato starch. 4) The form of 6 strains are long oval and round and most of them are similar to the other yeast in size. 5) In giant colony the color was cream color and cream buff, and T-K-2 was formed by $15{\times}12mm$ on diameter and by 3.5mm on high. 6) Optimum temperature of most of all strains is 25~ $300^{\circ}C$but T-K-4 is 28-30.deg.C. 7) Optimum pH is 3.4-4.6. 8) T-S-2 was died off at 65.deg.C, the other strains died $60^{\circ}C$. 9( Making Bun-kok with non-heated wheat bran .alpha.-amylase was more increased by 4.5-13.5 mg of glucose in reaction solution and .betha.-amylase more 1.6-3.4ml of N/10-$KMnO_4$ Solution than Bun-kok with heated wheat bran. 10) It seems that mycellium grows better than original in substance containing 0.4 ~ 1.2% of HCl. 11) Making Bun-kok to add 0.8% HCl, .alpha.-amylase was increased 9.93-20.7mg of glucose and .betha.-amylase ws increased 2.6~4.3ml of N/10-$KMnO_4$ solution to reaction solution. 12) 1.2%-HCl, or higher concentration, acts as inhibitor, in the meanwhile the concentration between 0.4~0.8% of HCl acts as activator. 13) We must make Bun-kok for 42 hours, at 28~$30^{\circ}C$) After we made Bun-kok using S-O-II and R-J-I one by one, Bun-kok which mix each other in equal quantity is increased more than original on enzyme acrivity. 15) Oxidation is the best way of refining sweet potato starch in N/10-phosphate buffer solution (pH 7.5). 16) When we prepared sweet potato starch, first pH was 3.0.

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Effects of Dietary Fish Oil, Vitamin E and C Supplementation on DHA Deposition and Shelf-Life in Broiler Chickens (어유, 비타민 E 및 C의 급여가 닭고기의 DHA 축적 및 저장성에 미치는 영향)

  • Kang, H.K.;Kim, S.H.;Kim, J.H.;Kang, G.H.;Yu, D.J.;Na, J.C.;Kim, D.W.;Seo, O.S.;Kim, G.H.;Park, B.S.
    • Korean Journal of Poultry Science
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    • v.34 no.4
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    • pp.259-269
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    • 2007
  • This study was compared the effect of shelf-life and DHA accumulation in chicken meat from broilers fed experimental diets for two weeks($21{\sim}35$ days) of growers. Two hundred-ten male Ross broilers, 1 day of age, were randomly allocated to seven treatment groups. Experimental diets were assigned to each of the seven groups: control diet containing tallow, T1 with 1.00% fish oil, T2 with 2.00% fish oil, T3 with 2.00% fish oil, 200 ppm vitamin E and 200 ppm vitamin C, T4 with 2.00% fish oil and 200 ppm vitamin C, T5 with 2.00% fish oil and 200 ppm vitamin E, and T6 with 3.00% fish oil. The levels of DHA in chicken meat was the highest in T6, and T1 in breast muscle and thigh muscle with skin was higher than that of $T2{\sim}T5,\;T2{\sim}T5$ in raw chicken meat and wing with skin was about two-fold higher than that of T1. The contents of DHA in chicken meat according to storage days were significantly reduced to 42.30%, 49.38% and 48.51% in T1, T2 and T6, respectively, and this decrease was higher than that of T3, T4 and T5 (p<0.05). Particularly, the rate of reduction of DHA was the lowest in the T3 and T5, which were the lowest in TBARS(thiobarbituric acid reactive substances). TBARS increased in the order of T6, T2 and T1, but reduced in the order of T3, T5 and T4 according to storage days, and there was a significant difference among the treatment groups (p<0.05).

Tocotrienol and Tocopherol Contents of Rice Bran by Milling Recovery (도정율에 따른 미강의 Tocotrienol과 Tocopherol 함량)

  • Park Kyeong-Yeol;Kang Chang-Sung;Cho Young-Cheol;Lee Yong-Sun;Lee Young-Hyun;Lee Young-Sang
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.49 no.6
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    • pp.468-471
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    • 2004
  • Tocotrienol $(T_3)$ and tocopherol (T) are well-known antioxidant vitamin E isomers that are enriched in rice bran, most of which is removed during polishing process. To verify the polishing-dependent fractional content of tocotrienol and tocopherol, harvested brown rice of 4 cultivars were polished by 4.0, 6.4, 8.0, 9.6, and $12\%$ (w/w) and resultant bran powder and rice were used for $T_3$ and T analysis. Polishing degree affected bran $T_3$ content in that bran polished by $6.4\%$ exhibited highest $T_3$ content compared to other polishing degrees except in cv. Chucheongbyeo which showed similar $T_3$ content from 4.0 to $8.0\%$ polishing. In case of tocopherol, bran polished by $8.0\%$ exhibited highest T content in all tested cultivars. In general, $T_3$ distributed in higher quantity in exterior i.e., in less polished bran, while T showed relatively less decrease with enhanced polishing degree. Consequently, total vitamin E content in bran as calculated by the summation of $T_3$ and T became less dependent on polishing degree in that bran polished between 6.4 to $9.6\%$ exhibited no statistical differences. The rice of cv. Chuchongbyeo, remained after polishing, exhibited similar vitamin E content up to $6.4\%$ polishing, above which significant vit E loss could be observed. These results suggest that polishing less than $6.4\%$ is desirable to minimize the loss of tocotrienols and tocopherols during polishing.

Thermal Stability of $\textrm{Fe}_{80-x}\textrm{P}_{10}\textrm{C}_{6}\textrm{B}_{4}\textrm{M}_{x}$(M=Transition Metal) Amorphous Alloys ($\textrm{Fe}_{80-x}\textrm{P}_{10}\textrm{C}_{6}\textrm{B}_{4}\textrm{M}_{x}$(M=Transition Metal) 비정질합금의 열적안정성)

  • Guk, Jin-Seon;Jeon, U-Yong;Jin, Yeong-Cheol;Kim, Sang-Hyeop
    • Korean Journal of Materials Research
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    • v.7 no.3
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    • pp.218-223
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    • 1997
  • At the aim of finding a Fehased amorphous alloy with a wide supercooled liquid region (${\Delta}T_{x}=T_{x}-T_{g}$) before crystallization, the changes in glass transition temperatudfI$T_{g}$ and crystallization temperature ($T_{x}$) by the dissolution of additional M elements were examined for the $Fe_{80}P_{10}C_{6}B_{4}$(x~6at%. M= transition metals) amorphous alloys. The ${\Delta}T_{x}$ value is 27K for the Fe,,,P,,,C,,R, alloy and increases to 40K for the addition of M=4at%Hf, 4at%Ta or 4at%Mo. The increase in ${\Delta}T_{x}$ is due to the increase of $T_{x}$ exceeding the degree in the increase in $T_{g}$. The $T_{g}$ and $T_{x}$ increase with decreasing electron concentration (e/a) from about 7 38 to 7.05. The decrease of e/a also implies the increase in the attractive bonding state between the M elements and other constitutent elements. It is therefore said that $T_{g}$ and $T_{x}$ increase kith increasing attractive bonding force.

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Effect of Plowing Frequency and Sowing Dates on the Agronomic Characteristics, Feed Value, Weed Yield and Palatability of Silage Corn (경운횟수와 파종기 이동이 사일리지용 옥수수의 생육특성, 사료가치, 잡초발생 및 가축의 기호성에 미치는 영향)

  • Lee, Sang-Moo;Kim, Byoung-Tae;Hwang, Joo-Hwan;Jeon, Byoung-Tae;Moon, Sang-Ho
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.27 no.3
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    • pp.209-218
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    • 2007
  • This experiment was conducted to investigate effect of plowing frequency and sowing dates on the agronomic characteristics, feed value, weed yield and palatability of silage corn. Treatments were a basal treatment(C: May 5 seeding, plowing once, weeding control once), T1(May 12 seeding, plowing twice, weeding control 0 time), T2(May 19 seeding, plowing three times, weeding control 0 time, T3(May 26 seeding, plowing four times, weeding control 0 time) and T4(June 2 seeding, plowing five times, weeding control 0 time). The experiment was performed at the College of Life and Natural Sciences of Sangju University in Sangju in 2006. The plant height and ear height showed highly in order to C > T1 > T2 > T3 > T4 treatment, leaf length was the highest at T2 (96.0cm). Leaf width and number of dead leaf were the highest at C and T3 (11.2cm), C, C and T1 (4.6), respectively. Stem diameter was the highest at T3 as 31mm, while T2 was the lowest as 25mm (p<0.05). Ear circle showed highly in order of C > T1 > T4 > T3 > T4 (p<0.05), and tip filling degree was the highest at C treatment as 8.8, while T4 treatment was the lowest as 6.0 (p<0.05). The stem hardness and grain hardness were C < T1 < T2 < T3 < T4 (p<0.05). Stem saccharinity was T1(6.1%) was the highest, while T2(3.0%) was the lowest(P<0.05). Fresh yield of weed was the lowest at C treatment as 500 kg/ha, but T1 treatment was the highest as 44,100 kg/ha (p<0.05). Weed coverage rate showed highly in order of T1 > T2 > T3 > T4 > C treatment (p<0.05). Fresh yield of corn was the highest at C treatment as T3,550 kg/ha, but T4 treatment was the lowest as 65,500 kg/ha (p<0.05). Dry matter yield of corn showed highly in order of C(26,978 kg/ha) > T1(26,130 kg/ha) > T2(20,255 kg/ha) > T3(20,255 kg/ha) > T4(17,508 kg/ha) treatment (p<0.05). Crude protein content was T1(7.69%) > T4(7.42%) > T2(6.34%) > T3(5.99%) > C(5.91%) treatment (p<0.05), and Crude fat content showed highly in order of C (2.13%) > T1(2.04%) > T2(1.96%) > T3(1.95%) > T4(1.84%) treatment. Relative palatability of Holstein, Korean native goat and spotted deer was the highest at C treatment, but Korean native cattle was the highest at T1 treatment.

Synthesis of Dioxolane-T Related Nucleosides as Potential Anti-HIV Agent (항 AIDS약물 Dioxolane-T와 관련성이 있는 Dioxolane 뉴클레오사이드 합성)

  • 유정만;서희경;최보길;정병호;홍준희;천문우
    • YAKHAK HOEJI
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    • v.37 no.6
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    • pp.591-597
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    • 1993
  • Two new 6-azauracil dioxolane nucleosides which are related to Dioxolane T and expected to have anti-HIV activity were asymmetrically synthesized. The key intermediate 8 have been synthesized in ten steps from D-mannose and condensed with 6-azauracil to give 13 and 14 after desilylation, respectively.

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