YAKHAK HOEJI (약학회지)

The Pharmaceutical Society of Korea (대한약학회)
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Synthesis of Dioxolane-T Related Nucleosides as Potential Anti-HIV Agent

항 AIDS약물 Dioxolane-T와 관련성이 있는 Dioxolane 뉴클레오사이드 합성

  • Published : 1993.12.01
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Abstract

Two new 6-azauracil dioxolane nucleosides which are related to Dioxolane T and expected to have anti-HIV activity were asymmetrically synthesized. The key intermediate 8 have been synthesized in ten steps from D-mannose and condensed with 6-azauracil to give 13 and 14 after desilylation, respectively.

Keywords

References

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