• Korean Journal of Ecology and Environment
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• v.54 no.3
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• pp.229-239
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• 2021

Thamnaconus modestus, distributed in the Northwest Pacific, has high economic value and is used in various seafood. In this study, the morphological and genetic characteristics of T. modestus and T. septentrionalis were compared and analyzed. We observed the external and internal morphology of T. modestus, sketched skeletal elements, and analyzed phylogenetic evolutionary relationships using the cytochrome c oxidase subunit I (COI) gene on mitochondrial DNA compared to T. septentrionalis. The T. modestus observed in this study had blackish-brown patterns irregularly scattered on the gray-brown body, and the fins were blue-green. Genetic analysis results based on the COI sequences of T. modestus showed seven types of base sequence variation; however, the homology was more than 98.8%. In addition, as a result of comparison of the COI nucleotide sequences and phylogenetic analysis in Tetraodontiformes, two T. septentrionalis sequences (JN813099, MW485059) were similar to T. modestus with 99% homology, and the other two T. septentrionalis sequences (EF607583, KP267619) were similar to those of species belonging to another genus Thamnaconus with 95% homology with T. modestus. It was not easy to classify the species based on morphological characteristics, and phylogenetic analysis between T. modestus and T. septentrionalis confirmed the difference in classification. These results provide the external and internal morphology of T. modestus and will be used as important information for the taxonomic study of T. modestus and T. septentrionalis.

• Journal of the Korea Society of Computer and Information
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• v.14 no.10
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• pp.175-187
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• 2009

This paper shows trends in domestic and foreign web accessibility. To disclose the web accessibility observance rate, seven central adminstration institutions and another seven north-eastern cities in Gyeong gi-Do and seven major IT companies were evaluated. KADO-WAH 2.0 was used for showing the observance rate. The evaluation criteria was that of Internet Web contents accessibility Guidelines 1.0. The evaluation was limited to Guideline 1 and Guideline 2 of non-text contents and the restricted frame usage and the keyboard-only operation. The average points for three items are as follows: 65.56% for North-Eastern cities in Gyeong gi-Do and 43.71% for Central adminstration institutions and the average 29.33% for major IT companies. The observance rate was highest by 99.3% in Human-rights committee among the central administration institutions. With the observance rate of 98%, Namyang-ju city came first in Gyeong gi-Do area. Samsung electronics was the highest with 63.66% in observance rate. The Central adminstration got lowered from the average 82.14% in 2006 to the average 54.28% in 2009, with the result of 27.86% down. Accordingly, the urgent improvement for Central adminstration and Local adminstration in web accessibility is asked for. The same is true with major IT companies in web accessibility.

• The Journal of the Convergence on Culture Technology
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• v.10 no.2
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• pp.555-563
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• 2024

We were selected oriental medicinal herbs known to be effective in strengthening muscles, improving sarcopenia, treating arthritis and osteoporosis. Amino acids have been reported to be associated with the above-mentioned effects. During the manufacturing process of water extracts of ginseng and samchae, the content of arginine, a basic amino acid, was significantly reduced. The decrease was 99.48mg/100ml for steamed red ginseng compared to 114.07mg/100ml for dried white ginseng, and 54.69mg/100ml for steamed samchae compared to 118.90mg/100ml for dried samchae. The extracts of the wild roots of Acanthus apias and the above-ground twigs of Acanthus apias showed significantly higher DPPH and ABTS radical scavenging activities. Meanwhile, DPPH activity was higher in steamed red ginseng and steamed samchae compared to dried white ginseng and dried samche, but ABTS activity increased to 66.88% for steamed red ginseng compared to 41.96% for dried white ginseng, but was 77.48% for dried samchae and 77.52% for steamed samchae.

• Ocean and Polar Research
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• v.25 no.3
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• pp.249-256
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• 2003

An immunological method was developed in this study to quantify reproductive output of the female butter clam, Saxidomus purpuratus. A clam egg-specific polyclonal antibody was developed using the purified butter clam egg as an antigen. An indirect Enzyme-Linked Immunosorbent Assay (ELISA) was used in quantitative measurement of the eggs. Size of the butter clam eggs ranged from $70.81{\pm}7.52{\mu}m$ in histology or $88.56{\pm}11.31{\mu}m$ in intact eggs. The predominant egg constituent was protein (37.44%), followed by lipids (11.40%) and carbohydrates (9.68%). The SDS-PAGE showed that the egg proteins are composed of several peptides of molecular weights consisting of 247, 200, 99, 91, 54 and 47 kDa. ELISA indicated that the clams collected from Geoje Island in May 2002 produced 8.2 to 26.8% of their body weight as eggs or 9,307,309 to 31,156,333 with a mean of 16,931,893 eggs per individual clam. The results of this study thus suggest that indirect ELISA using rabbit anti-clam egg IgG as a primary antibody is a rapid, affordable and sensitive method to assess reproductive output of 5. purpuratus and possibly other bivalves using a small amount of eggs.

• Food Science and Biotechnology
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• v.16 no.2
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• pp.299-305
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• 2007

Response surface methodology was employed to optimize extraction conditions for finding the maximal functional properties of Pleurotus eryngii. Based on central composite design, the study plan was established with variations of microwave power (30-150 W), ethanol concentration (0-99.9%), and extraction time (1-9 min). Regression analysis was applied to obtain a mathematical model. A maximal yield of 47.86% was obtained when the microwave power, ethanol concentration, and extraction time were set at 122.7 W, 42.14%, and 8.3 min, respectively. A maximized electron donating ability of 93.32% was found under the following conditions: a microwave power of 144.19 W, an ethanol concentration of 49.52%, and an extraction time of 6.7 min. When the microwave power, ethanol concentration, and extraction time were set at 125.43 W, 40.54%, and 8.1 min, respectively, the maximum nitrite-scavenging ability was 80.47%. The optimum ranges of the extraction conditions, superimposed by the response surface methodology, could predicate a microwave power of 110-150 W, ethanol concentration of 0-45%, and extraction time of 7-9 min.

• Journal of Environmental Health Sciences
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• v.20 no.3
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• pp.1-12
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• 1994

Wastewaters being treated and final effluents were collected from 3 wastewater treatment plants of petrochemical industries, from August 31 to October 4, 1993 in an interval of 10 days, and further analysed by GC/FID to investigate discharge situation and removal efficiency on polycyclic aromatic hydrocarbons. The results were as follows: 1. The PAHs 294.57 $\mu$g/l were discharged in primary treatment effluent of plant A to manufacture vinyl acetate resin and acryl, and removed 54.51% by aeration and totally 84.71%. 2. The PAHs of the highest concentration were discharged in primary treatment effluent of plant B to manufacture PS resin and ABS resin, but removed 91.65% by activated sludge process and 98.19% by activated carbon to discharge PAHs of the lowest concentration comparing to another treatment operations. 3. The PAHs 99.96 $\mu$g/l of the lowest concentration were discharged in wastewater of plant C to manufacture epoxy resin, and removed 80.48% by activated sludge process. 4. B treatment system including activated carbon showed up the best removal efficiency of PAHs. Activated carbon therefore, seems to be effective as tertiary treatment. 5. Correlation coefficient of components to total PAHs was generally low, and correlation coefficients of phenanthrene, pyrene and acenaphthylene to total PAHs were each 0.98, 0.97 and 0.80, respectively. Correlation coefficient of the sum of phenanthrene, pyrene and acenaphthylene to total PAHs was 0.99, so that the sum of phenanthrene, pyrene and acenaphthylene was available as index to estimated total PAHs. 6. Phenanthrene and Chrysene were very well treated biologically and acenaphthylene and fluoranthene were untreated biologically. 7. Considering EPA standards, it seems that the concentration of phenanthrene, pyrene, fluoranthene, and benzo(k)fluoranthene is high level.

• Journal of Nutrition and Health
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• v.39 no.8
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• pp.795-800
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• 2006

In order to examine nutritional and behavioral risk factors of atopic dermatitis (AD) in Korean preschoolers, we analyzed data on 144 children aged 3-6 years with AD and their 434 healthy counterparts. The data included breast-feeding history, current weight, food behaviors assessed by the Mini Dietary Assessment (MDA), food intake by a semi-quantitative food frequency questionnaire, and behavior problems by the Preschool and Kindergarten Behavior Scale (PKBS). Multivariate logistic regression analyses were performed after controlling for preschool location and child's age, gender and total energy intake, as appropriate. There was no group difference of child and household characteristics. Breastfeeding history was related to lower AD risk (OR = 0.63, 95% Cl = 0.40-0.99), yet no statistically significant association was found with overweight status. Regarding food behaviors, AD risk was lower in children who drank milk at least one cup per day (OR = 0.52, 95% Cl = 0.35-0.78) and had regular meals (OR = 0.62, 95% Cl =0.42-0.92). Moreover, there were lower risks of AD in the second (OR =0.48, 95% Cl = 0.28-0.82) and the highest (OR = 0.55, 95% Cl = 0.32-0.94) intake quartiles as compared with the lowest quartile of kimchi intake. Similarly, AD risk was lower in the highest quartile of rice (OR = 0.51 Cl = 0.28-0.93) and the second quartile of fruit (OR =0.45, 95% Cl = 0.25-0.82) intakes. AD children had more problems in social interaction (OR = 1.97,95% Cl = 1.26-3.07) and independence (OR = 1.60, 95% Cl = 1.01 -2.54) measures than the healthy controls. Likewise, AD children tended to show more problem behaviors such as anxiety (OR = 1.63, 95% Cl = 0.99-2.69). Our results suggest that nutritional and behavioral dimensions are related to AD risk, yet the case control study design may preclude generalization of these results.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.25 no.2
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• pp.236-243
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• 2015

Objectives: This study sought to examine the association between long working hours and depressive symptoms among interns and residents in South Korea. Methods: We analyzed a cross-sectional survey of 1,661 interns and residents from the 2014 Korean Interns & Residents Survey. Total working hours during the preceding week was assessed and classified into five categories(i.e. less than 60 hours, 60-79 hours, 80-99 hours, 100-119 hours, and 120-168 hours). Depressive symptoms during the previous week were measured by using ten items from the Center for Epidemiologic Studies Depression Scale questionnaire. Multivariate negative binomial regression was applied to examine the association between long working hours and depressive symptoms after adjusting for potential confounders, including medical specialty and training year. All analyses were performed using STATA/SE version 13.0. Results: 86%(N=1,429) of interns and residents worked 60 hours or more per week. Compared to the "less than 60 hours" group, long working hours for interns and residents were significantly associated with depressive symptoms: "60-79 hours"(PR: 1.56, 95% CI: 1.05, 2.32), "80-99 hours"(PR: 2.27, 95% CI: 1.54, 3.33), "100-119 hours"(PR: 2.62, 95% CI: 1.76, 3.89), and "120-168 hours"(PR: 3.28, 95% CI: 2.21, 4.86). Conclusions: This study found that long working hours were prevalent among interns and residents in South Korea, and it was associated with depressive symptoms.

• Journal of Radiation Industry
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• v.9 no.3
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• pp.111-117
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• 2015

In this paper, production of $^{166}Ho$ by double neutron capture from HANARO research reactor was evaluated. This production approach provides $^{166}Ho$ with high specific activity. $^{164}Dy$ is transmuted into $^{165g+m}Dy$ by (n,${\gamma}$) reaction, then $^{165g+m}Dy$ is transmuted into $^{166}Dy$ by (n,${\gamma}$) reaction. At the end of neutron irradiation, population of $^{166}Dy$ atoms reaches highest point. And $^{164}Dy$ exists as a mixture with $^{165m}Dy$, $^{165}Dy$, $^{166}Ho$ and $^{165}Ho$ at this point. To obtain $^{166}Ho$ with high specific activity, Ho isotopes from irradiated target is separated out. Then $^{166}Ho$ decayed from $^{166}Dy$ is eluted at radioactive equilibrium state. At each step, the number of relevant nuclide is calculated by the state equation. The neutron irradiation time for maximum $^{166}Dy$ is calculated for 283 hour. When 100 mg target of $Dy_2O_3$ (96.8% enriched $^{164}Dy$) is used, possible activity of $^{166}Ho$ is 3.54 Ci($1.31{\times}10^{11}Bq$). For separation efficiency of Dy/Ho is 99.99%, $^{166}Ho/Ho$ is 0.62.

• Natural Product Sciences
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• v.27 no.2
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• pp.99-114
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• 2021

Type 2 diabetes mellitus (T2DM) and its complications are important noncommunicable diseases with high mortality rates. Protein tyrosine phosphatase 1B (PTP1B) and aldose reductase inhibitors are recently approached and advanced for T2DM and its complications therapy. Matricaria chamomilla L. is acknowledged as a worldwide medicinal herb that has many beneficial health effects as well as antidiabetic effects. Our research was designed to determine the most potential antidiabetic phytochemicals from M. chamomilla employing in silico study. 142 phytochemicals were obtained from the databases. The first screening employed iGEMdock and Swiss ADME, involving 93 phytochemicals. Finally, 30 best phytochemicals were docked. Molecular docking and visualization analysis were performed using Avogadro, AutoDock 4.2., and Biovia Discovery Studio 2016. Molecular docking results demonstrate that ligand-protein interaction's binding affinities were -5.16 to -7.54 kcal/mol and -5.30 to -12.10 kcal/mol for PTP1B and aldose reductase protein targets respectively. In silico results demonstrate that M. chamomilla has potential antidiabetic phytochemical compounds for T2DM and its complications. We recommended anthecotulide, quercetin, chlorogenic acid, luteolin, and catechin as antidiabetic agents due to their binding affinities against both PTP1B and aldose reductase protein. Those phytochemicals' significant efficacy and potential as antidiabetic must be investigated in further advanced research.