• Title/Summary/Keyword: 50 Years

Search Result 6,932, Processing Time 0.036 seconds

Antihypertensive Effect and Safety Evaluation of Vegetable Drink with Peptides Derived from Sardine Protein Hydrolysates on Mild Hypertensive, High-normal and Normal Blood Pressure Subjects (정어리 단백질 유래 펩티드를 배합한 야채 과일 음료의 경증 고혈압자, 정상고치(高値)혈압자 및 정상혈압자에 대한 강압효과와 안전성의 평가)

  • Kawasaki, Terukazu;Chen, Jian-Jun;Fukushima, Yoichi;Kegai, Kaori;Seki, Eiji;Osajima, Katsuhiro;Itoh, Kazue;Matsui, Toshiro;Matsumoro, Kiyoshi
    • Proceedings of the Korean Society of Food Hygiene and Safety Conference
    • /
    • 2004.11a
    • /
    • pp.59-70
    • /
    • 2004
  • A randomized double-blind placebo-controlled study was conducted on 63 subjects to determine the antihypertensive effect of a vegetable drink in which sardine protein hydrolysates containing a dipeptide, Valyl-Tyrosine (VY), were incorporated. The subjects, consisting of people with mild hypertension, high-normal blood pressure and normal blood pressure, were randomly divided into test (male/female=25.6, average age 50.1${\pm}$10.4 years old) and control groups (26/6, 49.0${\pm}$5.0). Each subjects in the test group was given 195g of the vegetable drink containing 0.5g of sardine peptides (sardine protein hydrolysates) with 0.4 mg of VY (test drink) once a day for 13 weeks in a row, and subjects in the control group were given the same amount of the vegetable drink without sardine peptides (control drink) in the same manner. In the test group, 40 subjects with mild hypertension of high-normal blood pressure (130 mmHg${\leq}$systolic blood pressure (SBP)<160 mmHg and/or 80 mmHg${\leq}$diastolic blood the start of the test to 134.4${\pm}$11.1 mmHg during the first week of the test period, after which similar values were seen throughout the test period (13 weeks). Compared to the control group, the difference in SBP from vaseline was statistically significant in the test group throughout the intake period. DBP also decreased significantly from 88.0${\pm}$7.9 mmHg at baseline to 83.5${\pm}$8.6 mmHg after 13 weeks. In the control group, SBP and DBP were 140.8${\pm}$8.4 mmHg and 90.5${\pm}$6.6 mmHg respectively at the start of the test, and neither decreased during the test period. In subjects with normal blood pressure, neither those in the test group nor those in the control group showed a significant change in SBP and DBP during the test period. An excessive ingestion test was performed on 25 subjects with hypertension, mild hypertension, high-normal blood pressure, and normal blood pressure by giving 585g (3 times the recommended amount of intake) of the test drink for 14 days in a row. As a result, a significant decrease of blood pressure was observed in the hypertension, mild hypertension and high-normal blood pressure groups, but no excessive decline in blood pressure or any side-effects were associated with any subjects during the test period. In the groups with normal blood pressure, the excessive ingestion of the test drink did not affect blood pressure. In these two studies, physical check-ups and biochemical analyses of blood and urine were also conducted in all subjects, and no abnormalities were observed. These results suggest that the test drink containing sardine protein hydrolysates exhibited the antihypertensive effect in only the subjects with mild hypertension or high-normal blood pressure. No adverse effects were observed in either hypertensive of normotensive subjects.

  • PDF

Achievement of Excavation of Gwiam(Turtle Rock) and Nakseojae Restoration in Bogil-do Yun,Seondo Wonlim (보길도 윤선도원림(명승 제34호) 낙서재지역 원형복원과 귀암(龜巖) 발굴의 성과)

  • Lee, Won-Ho
    • Journal of the Korean Institute of Traditional Landscape Architecture
    • /
    • v.30 no.3
    • /
    • pp.111-120
    • /
    • 2012
  • This study regards a series of achievement on Wonlim(Garden) Cultural Properties Excavation Project, led by field of landscape architecture. It will mainly describe excavation results of Gwiam(龜巖: Turtle rock) and historical value of it in terms of Nakseojae(樂書齋) restoration in Bogil-do Yun,Seondo Wonlim(Scenic Sites, No.34). Gwiam(Turtle rock) was found 14.6m apart from the north of Nakseojae, and it covered with 10~15m topsoil tilted toward Nakseojae, The size of Gwiam, which was Granite, was 360cm length, 270cm width, 95cm high. The Edge of Gwiam's North west part was of triangular shape forming Turtle head. The back of the Turtle head was form of Tortoise-shell because of wide backboard with both side groove. The southeast part of Gwiam projected was Turtle's tail. This Granite was obvious Turtle shape artificially made, and there are less likely to relocate from place to place. This Turtle-shaped Gwiam is important landmark for Nakseojae, which is one of the four spiritual creatures written in Bogildoji(甫吉島識) and Gosanyugo(孤山遺稿) by Yunwi. According to Bogildoji, it is estimated that Gwiam were on the axis with Soeunbyung(小隱屛), Nakseojae and was buried when Yiguan(Gosan's grandson) reconstructed a building. Also, it was place for enjoying the moon. But, Even after three times excavation in Nakseojae, there was no way to identify further information regarding Gwiam, so it was a matter of mystification. As a result of this study, Gwiam is laid bare to light in at least 260 years, so it is good example for boosting importance of landscape architecture field and restoring Nakseojae. Furthermore, firm base-soil was discovered in 135m high Rock Mass below, so natural ground of Nakseojae can be estimated by this basis. To be conclusion, Preservation Process for Gwiam and Estimation Space through interpretation of four spiritual creatures(四靈) in Gosan's Poetry should be continue.

An Analysis of 94 Percutaneous Renal Biopsies (경피적 신생검 94례에 대한 분석)

  • Kang, Ho-Jung;Lim, Sang-Woo;Do, Joo-Yeung;Yoon, Kyung-Woo
    • Journal of Yeungnam Medical Science
    • /
    • v.12 no.1
    • /
    • pp.84-95
    • /
    • 1995
  • A clinical and histopathological study was performed on ninety-four patients with nephrotic syndrome (91 idiopathic and 3 secondary) who were admitted to Department of Internal Medicine, Yeungnam University Hospital during the period of nine years, from January 1985 to May 1994. The results were as following. 1. the ratio of male to female was 1.76:1. In young age group, minimal change was the most predominant type. In old age group, membranous glomerulonephritis and focal glomerulosclerosis were predominant types. 2. The primary nephrotic syndromes were 96.8% and secondary nephrotic syndromes were 3.2%. Histopathologic findings of 94 renal biopsy tissue were classified into minimal change (43.6%), mesangial proliferative glomerulonephritis (29.8%), membranous glomerulonephritis (12.8%), TypeI membranous proliferative glomerulonephritis (4.3%), focal glomerulosclerosis (3.2%) and others (6.4%). 3. The response of eighty-six patients treated with steroid showed complete remission in 51.2%, partial remission in 20.9%, steroid dependent in 2.3%, and no effect in 25.6% of cases respectively. The response to steroid therapy was most effective in the patients with minimal change lesion. 4. In the patient with membranous proliferative glomerulonephlitis, long-term angiotensin converting enzyme inhibitor treatment showed less deterioration of renal function.

  • PDF

Age-Based Characteristics of West Syndrome in Patients with Mitochondrial Disease (미토콘드리아 질환에서 웨스트 증후군 환자의 경련 발생 연령에 따른 임상 양상 비교)

  • Choi, Young Ha;Baek, Min-Seong;Na, Ji-Hoon;Kang, Hoon-Chul;Lee, Joon Soo;Kim, Heung Dong;Lee, Young-Mock
    • Journal of the Korean Child Neurology Society
    • /
    • v.26 no.4
    • /
    • pp.197-204
    • /
    • 2018
  • Purpose: West syndrome is a severe form of age-specific epilepsy that typically affects infants younger than 2 years of age with mitochondrial disease. We aimed to examine age-specific characteristics of the syndrome in these patients. Methods: We retrospectively analyzed 54 patients with West syndrome diagnosed with mitochondrial disease between March 2006 and March 2016. We compared treatment strategies and diagnostic and clinical variables between patients with early-onset (<6 months of age) and late-onset (${\geq}6$ months of age) seizures. Results: Seizure was the first symptom in 30 (90.9%) and 13 (65%) patients of the early-onset and late-onset groups, respectively (P=0.046). Delayed development was observed in 3 (9.1%) and 7 (35%) patients of the early-onset and late-onset groups, respectively (P=0.023). Lactate levels were normal in 17 patients (55%) of the early-onset group and 5 (25%) of the late-onset group (P=0.036), while initial brain magnetic resonance imaging (MRI) findings were normal in 23 (67.6%) and 8 (40%) patients of the early-onset and late-onset groups, respectively. Final MRI findings were abnormal in 32 patients (94.1%) of the early-onset group and 18 (90%) of the late-onset group (P=0.036). Although ketogenic diets reduced seizure frequency in both groups, the difference was not significant. Conclusion: There is no significant difference in epilepsy-related variables when patients are divided based on a cut-off age of 6 months. However, differences in the first symptom at onset and MRI findings were observed. Although lactate levels were not of significant diagnostic value in the early-onset group, they may be in the late-onset group.

Present Status and Future Prospect on Fishing Industry in North Korea (북한수산업(北韓水產業)의 현황(現況)과 전망(展望))

  • Lee, Byoung-Gee;Kim, Jin-Kun;Choe, Jong-Hwa
    • Journal of Fisheries and Marine Sciences Education
    • /
    • v.3 no.2
    • /
    • pp.73-82
    • /
    • 1991
  • In recent years, the communication and the trade between the Republic of Korea(South Korea) and the Communist bloc has been activated. The simultaneous entrance of South Korea and North Korea to the United Nations will accelerate the political dialogue and also the trade which is indirectly carried out through a third country at present will be turned into direct way. Fisheries products are also treated as one of the important trade goods and there is a hopeful prospect that the amount of trade will be steeply increased in the near future. Furthermore, there is a great possibility of development up to the joint utilization of fishing grounds or the joint investment in fisheries projects. Concerning such points, since it is very much important to understand the present status of fisheries in North Korea, the author made a study on this field as requested by the Board of Unification, and report a part of the study here. The prominent character of North Korea's ruling sea area is that the sea is completely separated into two regions-the East Sea Region and the West Sea Region-and no continuity exists between them. The East Sea Region locates in the fringe of the biggest fishing ground of the world-the North Pacific Ocean-and very rich in resources not only warm water fishes but also cold water fishes. Especially alaska pollack, Theragra chalcogramma, is caught abundantly in this region. Contrary to that, fishing activity in the West Sea Region seems to be interrupted in winter. Even though some valuable warm water fishes-yellow corvenia, Pseudosciaena manchurica, and hair tail, Trichiurus lepturus, and so forth-come to this region from spring to summer along the coast line of this region for spawning, and vigorous fishing activity is carried out. But the most of them migrate southward to the neighboring waters of Cheju Island for wintering from autumn to winter, and so the fishing activity in this region seems to be interrupted greatly during winter. The total number of fishing boats in North Korea is estimated at 36 thousand and the rate of mechnization at about 70% compared with 99 thousand and 78% in South Korea. North Korea proclaimed an exclusive economic zone of 200 nautical miles in 1977. Specific character of this zone is setting of military boundary zone, up to 50 miles from the base line in the East Sea Region and also it covers whole region of the economic zone in the West Sea Region. Especially in the East Sea Region she set up a straight base line which can not be permissible by the international law. North Korea's statistics on fisheries product has not been announced officially on account of her unique isolationism, but it can be estimated through several data procured. At the first, the amount of fisheries products in the North Korea is reported as about 1.7 million ${\frac{M}{T}}$ by Fisheries Statistics which issued by the FAO in 1987, but a North Korea's trade organization announced the amount as 3.5 million ${\frac{M}{T}}$ in 1988. The former seems to be underestimated and the latter must be an exaggeration. According to Chikuni, who is a Japanese worker for FAO, prepared the unofficial statistics based on the evidence which he collected through the fineries development plan of the FAO/UNDP, and estimated the mean amount between 1982 and 1984 was 2.4 million ${\frac{M}{T}}$ or so. The Board of Unification estimated on the basis of various factors that the amount was 2.2 million ${\frac{M}{T}}$ or so in 1987 and in 1988. This seems to be the most reasonable. To solve the chronic lack of foreign currency, North Korea makes effort on the development of fisheries, and has even aimed fisheries product at 11 million ${\frac{M}{T}}$ by 1993, but this target looks unrealistic under the present circumstances. Somehow, we can exploit her extreme policy which has gone so far as to establish such an excessive and impractical target. Nevertheless this will be helpful to promote the joint development of the fishery activity between South Korea and North Korea.

  • PDF

Compaction Characteristics of Multi-cropping Paddy Soils in South-eastern Part of Korea (우리나라 동남부 다모작 논토양의 경반화 특성)

  • Yun, Eul-Soo;Jung, Ki-Yeul;Park, Ki-Do;Sonn, Yeon-Kyu;Park, Chang-Yeong;Hwang, Jae-Bog;Nam, Min-Hee
    • Korean Journal of Soil Science and Fertilizer
    • /
    • v.44 no.5
    • /
    • pp.688-695
    • /
    • 2011
  • This study was carried out for some survey about soil compaction in the multi-cropping system of paddy field. Investigated sites were 90 farmer's fields in south-eastern part of Korea. The tillage practices season was different according to cropping system of paddy; in spring for mono rice cultivation and in autumn for the multi-cropping field. The average tillage depth in investigated sites was about 25 cm, however, it is different between the farmer's tillage practices and soil characteristics. It is high correlation to tillage deep and minimum resistance of penetration. The reaching soil deep to maximum resistance of penetration was about 27 cm, and average penetration resistance of the deep is 1.8~2.0 MPa for moderately fine-textured soils and more than 3.0 MPa for moderately coarse-textured soils. The difference of penetration resistance between cultivating and compacted layer was in order to sandy loam > clayey loam > clayey, and the difference was lesser in poorly drained soils than somewhat poorly ones. In the rice mono cropping field, the maximum resistance in no-tillage for 15 years was 1.18~1.25 Mpa at 20~25 cm in soil deep, however, the resistance of field with every year tillage practices was 2.03~2.21 Mpa. In the extremely compacted sandy loam textured soils, the penetration resistance at 30 cm in soil depth was drastically reduced by the subsoil from 5.2 Mpa to 3.2 Mpa, and the watermelon root in plastic film house was deep elongated.

An Analysis of Changes in Rice Growth and Growth Period Using Climatic Tables of 1960s (1931~1960) and 2000s (1971~2000) (우리나라 1960년대 (1931~'60)와 2000년대 (1971~2000) 기후표를 이용한 벼 생육 및 재배기간 변화 분석)

  • Lee, Jeong-Taek;Shim, Kyo-Moon;Bang, Hea-Son;Kim, Myung-Hyun;Kang, Kee-Kyung;Na, Young-Eun;Han, Min-Su;Lee, Deog-Bae
    • Korean Journal of Soil Science and Fertilizer
    • /
    • v.43 no.6
    • /
    • pp.1018-1023
    • /
    • 2010
  • Climatic change was observed and analyzed in view of impacts on agricultural ecosystem, inter alia on rice cropping. The changed climate gave rise to earlier transplanting of rice seedling and later harvest after 40 years. Also phenological change and prolonged growth duration was observed. The meteorological data was selected from the standardized climatological data of 30 year normals of 1960s and 2000s, which were published by Korea Meteorological Administration. Development stages and growing periods of rice crop were compared by analyzing critical and optimum temperatures of each growth stage during these two periods. The first appearance date of $15^{\circ}C$ was ranged from Apr. 29 to May 23 in the year-normals of 1960s and it varied from Apr. 24 to May 16 in the normals of 2000s. The difference of the first appearance date of $15^{\circ}C$ was 0~10 days earlier in the year-normals of 2000s than the 1960s. The last harvesting date was determined to be the last appearance date of mean air temperature $15^{\circ}C$. The difference in the last appearance date of $15^{\circ}C$ was 1 to 13 days later in the year-normals of 2000s than in 1960s. The plant height of a rice variety, Hwayoung-byeo was 101~109 cm in 4 local areas, Seoul, Kangneung, Kwangju and Daegu. The plant height became 1~4 cm taller under warm condition. Rice grain yields estimated with daily weather data for the year-normals of 1960s and 2000s were 453~580 kg $10a^{-1}$ and 409~484 kg $10a^{-1}$ respectively. Rice grain yield of the former period was 50~100 kg $10a^{-1}$ higher than that hat in the later period.

Aggregate of Korea in 2020 (2020년도 국내 골재 수급 분석)

  • Hong, Sei Sun;Lee, Jin Young
    • Economic and Environmental Geology
    • /
    • v.54 no.5
    • /
    • pp.581-594
    • /
    • 2021
  • In 2020, about 132 million m3 of aggregate was produced in Korea. Of the total domestic aggregates produced in 2020, about 33.3 % was sand and about 66.7% was gravel. It estimated that of the 132 million m3 of aggregates in Korea in 2020, about 52% was produced by screening crushed aggregate, by 36% by forest aggregate, 3% by land aggregate, 5.6% by sea aggregate and 2.5% by washing each other, and 0.4% by river aggregate. This indicates that screening crushed aggregate and forest aggregate are the main producers of domestic aggregates. Leading producing metropolitan cities were Gyeonggi-do, Gyeongsangnam-do, Chungcheongbuk-do, Gangwon-do, Chungcheongnam-do, Incheon in order decreasing volume, which together accounted for about 72.4% of total product. In 2020, aggregates were produced in 153 cities, about 67% of the 231 cities of Korea, 38 local governments have developed aggregates of more than 1 million m3, and the combined production of the 38 cities accounted for about 65% of national total. This means that the aggregate extraction trend of local governments is becoming larger and more concentrated. In 2020, at 153 local governments, a total of 889 operations produced aggregates with 420 operations by permission, 469 operations by declaration. A review of production by size of operation indicated that about 17 million m3 (12.8% of the total aggregate) was produced by 14 operations reporting production of more than 1 million m3. In about 420 operations, the maximum period of permit is 32 years to at least 2 months. When the remaining period of permit is taken into account, only about 55% of active operations can be developed the aggregate after 2021. In order to maintain the permitted aggregate volume by 2020 level, it will be necessary to obtain an extension permit or find new operation sites for at least 200 or more operations.

Changes in Spherical Aberration and Coma Aberration after Wearing Aspheric Soft Contact Lens in Young Myopes (젊은 성인 근시안에서 비구면 소프트 콘택트렌즈 착용 후 구면수차와 코마수차의 변화)

  • Lim, Dong-Kyu;Kwon, Hyeok;Lee, Koon-Ja
    • The Korean Journal of Vision Science
    • /
    • v.20 no.4
    • /
    • pp.469-482
    • /
    • 2018
  • Purpose : We investigated the change of spherical and comma aberrations after wearing aspheric soft contact lens (ASCL) in young myopes. Methods : Fifty young myopes ($23.15{\pm}1.70years$, spherical equivalent: $-2.90{\pm}1.75D$) were recruited and refractive errors were corrected using ASCL (Biotrue, Bausch+Lomb, USA). High order aberrations were measured in the 4 mm pupil size using the wavefront analyze and pupil sizes were measured with a pupillometer at the modes of scotopic condition (light off) at 3.5 m in the 100 lx illuminance condition. Results : Spherical aberrations and coma aberration of the 20s myopes were $0.026{\pm}0.031{\mu}m$ and $0.078{\pm}0.039{\mu}m$ respectively, and $0.019{\pm}0.026{\mu}m$ and $0.082{\pm}0.038{\mu}m$ after ASCL wear that spherical aberration was decreased and coma aberration was increased. However, spherical aberration was decreased in the 68% of the subject have positive spherical aberration, and increased in the 11% of the subject have negative spherical aberration. Coma aberration was increased in the 53% of the subject, did not change in the 19% of the subjects, and decreased in the 28% of the subject. Spherical aberration was not different with the refractive errors in low and moderate myopies, however, coma aberrations was higher in the higher myopes. Conclusion : In a scotopic condition without accommodation stimuli, spherical aberration is decreased after wearing ASCL, however in the subject have negative spherical aberration spherical aberration could be increased, and which is thought to be the influence of contact lens design and pupil size.

Gender politics and the monster-abject representation method of the posthuman age. - Focused on works by Kim Eon-hee and Han-Kang - (포스트휴먼 시대의 젠더정치와 괴물-비체의 재현방식 - 김언희와 한강의 작품을 중심으로 -)

  • Baik, Ji-yeon
    • Cross-Cultural Studies
    • /
    • v.50
    • /
    • pp.77-101
    • /
    • 2018
  • Even in our modern era, the projection of monsters in the recent literature contains the critical imagination of human existence for the posthuman age. The meaning of the monster-abject, especially as from the perspective of feministic criticism, contains criticism of the violent and oppressive patriarch as observed in the modern times. This article focuses on the gendered imagination of the discussions of the "abject" discussed by Julia Kristeva, and the "monstrous femine" discussed by Barbara Creed. Kim Eon-Hee's poems and Han Kang's novels, which have been examined extensively for analysis, show that the practical strategy of abject that goes beyond hate and sublime, wonder and joy through the imagination and concepts of monsters. The monster-abject strategy of Kim Eon-Hee's poem can be summarized by the narrative method of mirroring and the imagination of the truncated body. Mirroring falsification, which mimics the male speaker, is a method that some feminists strategically utilize in relation to the problem of female aversion in recent years as noted in the literature. In Kim Eon-Hee's poem, "becoming a man" and "imitating a man," through the method of mirroring appear as an image of cutting to dismantle the body. In that way, the narrative strategy of the abject that draws out abominations and bizarre effects which contains a strong critique of the patriarchal dominant ideology. The monster-abject strategy of Han-Kang's novel is embodied through the being of plants and the process of vegetarian-anorexia process. The world of the adject which was oppressed in the Han-Kang's novel, returns to the senses of the body through the symbol of the body. It is noted that the fictional characters who realize the repressed desire through the pathological symptom expressed by the female, go on to body perform active transformation. The sense of a body in a novel is not only a rejection of the world of animalman-civilization, but also a radically questioning of the noted and recognized boundaries between human beings and non-human being entities. The two writer's works show that the imagination of the monster-adject is not limited to rejecting the existing gender categories, but also goes in the direction of exploring the possibilities of various associated gender actions.