• JSTS:Journal of Semiconductor Technology and Science
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• 제16권4호
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• pp.443-450
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• 2016

The linearization technique for low noise amplifier (LNA) has been implemented in standard $0.18-{\mu}m$ BiCMOS process. The MOS-BJT derivative superposition (MBDS) technique exploits a parallel LC tank in the emitter of bipolar transistor to reduce the second-order non-linear coefficient ($g_{m2}$) which limits the enhancement of linearity performance. Two feedback capacitances are used in parallel with the base-collector and gate-drain capacitances to adjust the phase of third-order non-linear coefficients of bipolar and MOS transistors to improve the linearity characteristics. The MBDS technique is also employed cascode configuration to further reduce the second-order nonlinear coefficient. The proposed LNA exhibits gain of 9.3 dB and noise figure (NF) of 2.3 dB at 2 GHz. The excellent IIP3 of 20 dBm and low-power power consumption of 5.14 mW at the power supply of 1 V are achieved. The input return loss ($S_{11}$) and output return loss ($S_{22}$) are kept below - 10 dB and -15 dB, respectively. The reverse isolation ($S_{12}$) is better than -50 dB.

• JSTS:Journal of Semiconductor Technology and Science
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• 제11권4호
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• pp.295-301
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• 2011

A triple-band transceiver module for 2.3/2.5/3.5 GHz mobile WiMAX, IEEE 802.16e, applications is introduced. The suggested transceiver module consists of RFIC, reconfigurable/multi-resonance MIMO antenna, embedded PCB, mobile WiMAX base band, memory and channel selection front-end module. The RFIC is fabricated in $0.13{\mu}m$ RF CMOS process and has 3.5 dB noise figure(NF) of receiver and 1 dBm maximum power of transmitter with 68-pin QFN package, $8{\times}8\;mm^2$ area. The area reduction of transceiver module is achieved by using embedded PCB which decreases area by 9% of the area of transceiver module with normal PCB. The developed triple-band mobile WiMAX transceiver module is tested by performing radio conformance test(RCT) and measuring carrier to interference plus noise ratio (CINR) and received signal strength indication (RSSI) in each 2.3/2.5/3.5 GHz frequency.

• Journal of electromagnetic engineering and science
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• 제11권1호
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• pp.27-33
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• 2011

In this paper, we propose a high gain, current reused ultra wideband (UWB) low noise amplifier (LNA) that uses TSMC 0.18 ${\mu}m$ CMOS technology. To satisfy the wide input matching and high voltage gain requirements with low power consumption, a resistive current reused technique is utilized in the first stage. A ${\pi}$-type LC network is adopted in the second stage to achieve sufficient gain over the entire frequency band. The proposed UWB LNA has a voltage gain of 12.9~18.1 dB and a noise figure (NF) of 4.05~6.21 dB over the frequency band of interest (1~10 GHz). The total power consumption of the proposed UWB LNA is 10.1 mW from a 1.4 V supply voltage, and the chip area is $0.95{\times}0.9$ mm.

• 한국전자파학회논문지
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• 제9권3호
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• pp.386-398
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• 1998

본 논문에서는 군사용 레이다 장비에서 필수적인 연속검파 형태의 대수증폭기를 높은 다이나믹 레인지 및 낮은 대수 오차를 얻을 수 있도록 설계 제작하였다. 제작된 대수 증폭기는 하이브리드 형태로 구현되였으며,0.5l 1.5 GHz에서 dynamic range는 80 dB 이상, 대수오차는 $\pm$1.4 dB 이하, 잡음지수 5.5 dB 이하, 감도는 -76 d dBm, VSWR 2.0:1 이하의 특성을 나타내었다. 제작된 대수 증폭기는 기존의 MAlCOM사에서 제작된 대수 증폭기에 비해 다이나믹 레인지가 훨씬 높고 다른 특성면에서는 큰 차이가 없으므로, 크기 및 전력소모를 줄여서 레이다 시스템에 응용할 수 있을 것이다.

• 한국전자파학회논문지
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• 제13권8호
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• pp.764-768
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• 2002

본 논문에서는 (주)타키오닉스의 SiGe HBT 공정을 이용하여 double balanced Gilbert cell down conversion MMIC mixer를 구현한 결과를 제시하고, 이를 통해 RFIC 설계용 SiGe HBT 파운드리의 정확성과 신뢰성을 평가하였다. 제작된 Mixer는 3 V 동작 전압에서 10 mA의 전류를 소모하며, 2 GHz의 주파수 대역에서 17 dB의 Conversion Gain과 9.8 dB NF, -4.2 dBm Output 1 dB Compression Point, -27 dEc의 RF-IF Isolation의 특성을 나타내었으며 우수한 50 $\Omega$ 입. 출력 정합 특성을 갖는다. 시뮬레이션 결과와 측정결과는 거의 유사한 특성을 가지며, 이를 통해 SiGe HBT 모델 라이브러리의 정확성과 공정의 재현성을 검증할 수 있었다.

• 상하수도학회지
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• 제24권1호
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• pp.15-24
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• 2010

Coagulation can be used for pretreatment of NF membrane filtration. Foulants such as organic matter and particulate can be removed effectively with the process while high flux recovery is maintained. Recently various types of polyaluminium coagulants including polyaluminium chloride(PAC) are commercially available for water treatment. This study examines effects of polymeric Al and hydrolysis products of PAC on nanofiltration membrane performance. Dominant hydrolysis products were polymeric Al, $Al(OH)_3$, and ${Al(OH)_4}^{-1}$ at acidic, neutral, and alkaline pH conditions, respectively. Under acidic pH condition, flux decline was increased with increasing PAC concentrations, possibly due to polymeric Al adsorption on membrane pore and/or surfaces. For neutral and alkaline pH conditions, little flux decline was observed with increasing PAC concentrations except the highest ${Al(OH)_4}^{-1}$ concentration, with which rapid flux decline was shown. Removal of ionic matters was also varied with pH conditions in this study. Especially, conductivity removal was substantially low and $Ca^{2+}$ concentration in the permeate was quite high at neutral pH condition.

• Parasites, Hosts and Diseases
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• 제54권5호
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• pp.679-684
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• 2016

Clonorchiasis, caused by direct contact with Clonorchis sinensis worms and their excretory-secretory products (ESPs), is associated with chronic inflammation, malignant changes in bile ducts, and even cholangiocarcinogenesis. Our previous report revealed that intracellular free radicals enzymatically generated by C. sinensis ESPs cause NF-${\kappa}B$-mediated inflammation in human cholangiocarcinoma cells (HuCCT1). Therefore, the present study was conducted to examine the role of upstream Toll-like receptors (TLRs) on the initial host innate immune responses to infection. We found that treatment of HuCCT1 cells with native ESPs induced changes in TLR mRNA levels in a time-dependent manner, concomitant with the generation of free radicals. ESP-mediated free radical generation was markedly attenuated by preincubation of the cells with TLR1-4-neutralizing antibodies, indicating that at least TLR1 through 4 participate in stimulation of the host innate immune responses. These findings indicate that free radicals triggered by ESPs are critically involved in TLR signal transduction. Continuous signaling by this pathway may function in initiating C. sinensis infection-associated inflammation cascades, a detrimental event leading to progression to more severe hepatobiliary diseases.

• 한국해양바이오학회지
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• 제5권4호
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• pp.8-14
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• 2011

Although marine living organism contains a numerious number of compounds, it is difficult to collect these compounds in a large scale for medicinal application. However, in recent years, several bioactive compounds isolated from marine macroalgae have been proved to be able to provide potential sources for development of medicinal products because they can be obtained in large amount from marine. A number of studies have reported a variety of effects of marine macroalgae but a few anti-inflammatory activity of marine macroalgae have recently been published. Herein, we reviewed novel anti-inflammatory compounds recently isolated from marine brown algae, green algae and red algae. From this survey, in particular, some compounds contained in edible macroalgae exert anti-inflammatory effects with inhibition on cyclooxygenase-2 (COX-2), inducible nitric oxide synthase(iNOS) and matrix metalloproteinases (MMPs) activity regulated by nuclear factor-kappa B transcription factor that play a key role in cancer as well as inflammation, demonstrating to be able to potentially apply to development of anti-inflammatory agent for chemoprevention of cancer. Furthermore, some macroalgae and their compounds with both excellent anti-inflammatory activity and very low toxicity can select a potential candidates capable of preventing or treating several chronic inflammation such as colitis, hepatitis and gastritis, leading to cancer.

• Molecules and Cells
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• 제21권1호
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• pp.7-20
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• 2006

The major event in human immunodeficiency virus type 1 (HIV-1) infection is the death of many cells related to host immune response. The demise of these cells is normally explained by cell suicide mechanism, apoptosis. Interestingly, the decrease in the number of immune cells, such as non-CD4+ cells as well as CD4+ T cells, in HIV infection usually occurs in uninfected bystander cells, not in directly infected cells. It has, therefore, been suggested that several soluble factors, including viral protein R (Vpr), are released from the infected cells and induce the death of bystander cells. Some studies show that Vpr interacts directly with adenine nucleotide translocator (ANT) to induce mitochondrial membrane permeabilization (MMP). The MMP results in release of some apoptogenic factors such as cytochrome-c (cyt-c) and apoptosis-inducing factor (AIF). Vpr also has indirect effect on mitochondria through enhancing the level of caspase-9 transcription and suppressing nuclear factor-kappa B (NF-${\kappa}B$). The involvement of p53 in Vpr-induced apoptosis remains to be studied. On the other hand, low level of Vpr expression has anti-apoptotic effect, whereas it's high level of expression induces apoptosis. Extracellular Vpr also exhibits cytotoxicity to uninfected bystander cells through apoptotic or necrotic mechanism. The facts that Vpr has cytotoxic effect on both infected cells and bystander cells, and that it exhibits both proand anti-apoptotic activity may explain its role in viral survival and disease progression.

• 한국정보통신학회논문지
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• 제12권10호
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• pp.1731-1736
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• 2008

본 논문은 위성 DMB 수신을 위하여 2단 저잡음 증폭기를 결합한 단일급전 원편파 패치 안테나를 설계 및 제작하였다. 제작된 안테나의 크기는 $40{\times}40{\times}15mm$로서 상대유전율이 2.2인 테플론 기판으로 제작하였다. 측정 된 안테나의 입력 반사손실(10 dB 대역폭)과 3dB 축비의 대역폭은 각각 22 MHz와 28 MHz로 양호한 특성을 나타내었다. 제작된 2단 LNA는 각각 이득이 27.5[dB], 잡음지수는 1.27[dB], 입력 반사손실은 -15.4[dB], 출력 반사손실은 -18.9[dB]인 값을 갖는다. 시뮬레이션 결과와 실험 결과가 잘 일치하였다. 제안된 안테나 구조는 위성 DMB 단말기 수신안테나로 적용 가능하다.