• 농촌의학ㆍ지역보건
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• 제46권4호
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• pp.207-217
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• 2021

Objectives: The purpose of this study was to investigate the factors in which employee's health beliefs affect their intention to get COVID-19 vaccines. Methods: The participants of this survey were 237 emlpoyees living in Busan. Data were collected using structured online questionnaires from April 26th to May 6th, 2021. The data were analyzed in SPSS WIN version 25.0 using descriptive statistics, t-test, chi-square test, multiple logistic regression analysis. Results: At the average score for each area of health beliefs regarding COVID-19, self-efficacy was 4.45 points, perceived sensitivity 4.71 points, perceived severity 3.59 points, perceived benefit 4.46 points, and perceived disability 2.19 points. Monthly income, perceived sensitivity, perceived severity, and perceived benefit were found to be factors affecting the intention to get COVID-19 vaccines. Conclusions: In order to improve the vaccination intention of COVID-19, it is necessary for subjects to recognize the seriousness of the disease, increase their sensitivity to the disease, and actively promote and educate the community about the benefits of vaccination.

• 디지털융복합연구
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• 제18권12호
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• pp.459-468
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• 2020

본 연구는 간호대학생의 COVID-19 예방행위 수행정도에 영향을 주는 요인을 분석하고자 수행되었다. 2020년 4월 24일부터 5월 6일까지 1~4학년 195명 간호대학생이 온라인을 통한 자가보고식 설문조사에 응답하였다. 자료 분석은 SPSS/WIN 23.0으로 기술통계, Independent-test, ANOVA, Pearson's correlation coefficients, multiple regression analysis을 진행하였다. 연구결과 COVID-19에 대한 예방행위 수행은 지식과 불안에서 양의 상관관계를 보였다. 예방행위 수행에 영향을 미치는 요인은 지식(β=.418, p<.001), 불안(β=.280, p<.001), 자가격리 경험(β=-.107, p<.05)으로 설명력은 40.4%였다. 결론적으로 간호학생들의 COVID-19에 대한 정확하고 긍정적인 지식 형성이 필요하며 일상생활에서 예방행위 수행을 실천할 수 있는 교육프로그램의 개발과 적용이 필요하다.

• 한국직업건강간호학회지
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• 제30권4호
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• pp.232-242
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• 2021

Purpose: This study investigated the occupational status and job stress of visiting nurses during the COVID-19 pandemic. Methods: Participants were 151 visiting nurses working in the public health services in Seoul and Gyeonggi-do. The study was conducted using a structured online questionnaire. Results: The average age of the visiting nurses was 49.5 years. A occupational period was 38.4% of the participants had worked for a period of 6-10 years and 34.5% of them had worked for a period of 11 years or more. In terms of employment type, 74.8% had permanent contracts and 13.9% had fixed terms. 93.4% of nurses were working on COVID-19-related work; and 57.6% of them were working more than 50% of their work. Each visiting nurse provided health services for a total of 436.4 cases on average and the per day count was 14.3 cases. The service was provided through home visits or phone consultations. The results of the job stress were relationship conflict (60.92±20.72), job demand (59.05±14.10), job autonomy (57.83±14.63), job instability (45.25±27.37), organizational system (44.97±17.21), workplace culture (42.71±18.00), and inadequate compensation (35.29±18.14). There was a significant difference in job stress according to the proportion of COVID-19 work was 'workplace culture' (p=.023), Job autonomy (p=.053) and Inappropriate compensation(p=.054). Conclusion: In order to provide a stable working environment for visiting nurses and effective public visiting health services during unexpected circumstances, such as the COVID-19 pandemic, it is necessary to promote progressive policies and systemic improvements.

• Genomics & Informatics
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• 제21권1호
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• pp.4.1-4.18
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• 2023

Coronavirus disease 2019 (COVID-19) is an inflammatory and infectious disease caused by severe acute respiratory syndrome coronavirus 2 virus with a complex pathophysiology. While COVID-19 vaccines and boosters are available, treatment of the disease is primarily supportive and symptomatic. Several research have suggested the potential of herbal medicines as an adjunctive treatment for the disease. A popular herbal medicine approved in the Philippines for the treatment of acute respiratory disease is Vitex negundo L. In fact, the Department of Science and Technology of the Philippines has funded a clinical trial to establish its potential as an adjunctive treatment for COVID-19. Here, we utilized network pharmacology and molecular docking in determining pivotal targets of Vitex negundo compounds against COVID-19. The results showed that significant targets of Vitex negundo compounds in COVID-19 are CSB, SERPINE1, and PLG which code for cathepsin B, plasminogen activator inhibitor-1, and plasminogen, respectively. Molecular docking revealed that α-terpinyl acetate and geranyl acetate have good binding affinity in cathepsin B; 6,7,4-trimethoxyflavanone, 5,6,7,8,3',4',5'-heptamethoxyflavone, artemetin, demethylnobiletin, gardenin A, geranyl acetate in plasminogen; and 7,8,4-trimethoxyflavanone in plasminogen activator inhibitor-1. While the results are promising, these are bound to the limitations of computational methods and further experimentation are needed to completely establish the molecular mechanisms of Vitex negundo against COVID-19.

• Pediatric Infection and Vaccine
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• 제29권1호
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• pp.28-36
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• 2022

목적: 5-11세 소아에서 코로나19 백신의 효능과 안전성을 평가하기 위해서 체계적 문헌고찰을 시행하였다. 방법: 2022년 1월 4일까지 Ovid-MEDLINE 및 medRxiv를 검색하여 문헌을 선정하고 자료를 추출하였다. 근거 수준을 평가하기 위해 GRADE 도구를 사용하였다. 결과: 총 1,675 건의 연구가 일차적으로 검색되었고 최종적으로 5편의 연구가 포함되었다. 서로 다른 4개의 코로나19 백신(BNT162b2, mRNA-1273, CoronaVac, BBIBP-CorV)에 대한 무작위 대조군 연구 결과들은 5-11세 연령에서 각 백신의 양호한 면역원성과 안전성을 보여주었다. 미국에서 5-11세 소아 연령에서 BNT162b2 백신 접종 후 이상사례 모니터링 연구에서는 승인 전 임상시험을 통해 예상되었던 국소반응 및 전신반응이 보고되었으나 중대한 이상사례는 거의 보고되지 않았다. 결론: 5-11세 연령에서 코로나19 백신 접종에 대한 데이터는 제한적이다. 이 연령에서 코로나19 백신의 안전성과 효과에 대한 체계적인 평가를 위해 지속적이고 포괄적인 모니터링이 필요할 것으로 보인다.

• 한국컴퓨터정보학회논문지
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• 제25권11호
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• pp.179-185
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• 2020

본 연구에서 우리는 COVID-19의 사망에 대한 영향요인과 혈액변수의 타당도를 제안하였다. 이 연구를 위하여 질병관리본부 중앙방역대책본부에서 제공하는 2020년 4월 30일까지 격리해제되었거나 사망한 COVID-19확진자 5628명의 임상역학정보를 활용하였으며, 자료는 R 3.4.1을 사용하여 분석하였다. 분석결과, 사망에 대한 위험요인으로 치매(HR 7.03), 많은 나이(HR 5.39), 높은 림프구(HR 4.66), 암(HR 4.27), 호흡곤란(HR 3.25), 만성폐쇄성 폐질환(HR 3.22), 의식변화(HR 3.13), 심장질환(HR 2.24), 높은 혈소판(HR 2.14), 비정상 이완기 혈압(HR 2.02), 열(HR 1.69)이 확인되었다. 사망에 대한 혈액검사의 타당도는 림프구, 헤모글로빈, 헤마토크리트, 혈소판, 백혈구 순으로 정확도가 높았다. 그러므로 COVID-19 환자를 치료할 때 사망의 위험요인으로 확인된 초기 임상적 특징 및 기저질환, 혈액검사의 소견을 고려하여 보다 효율적인 관리가 가능하도록 해야 할 것이다.

• 한국융합학회논문지
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• 제13권1호
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• pp.489-498
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• 2022

본 연구는 COVID-19 상황에서 지역거점병원 간호사의 직무만족도에 영향 요인을 확인하고자 수행되었다. 자료는 H도의 4개 지역거점병원에 근무 중인 간호사 230명으로부터 설문지를 통하여 수집하였다. 수집한 자료는 SPSS/WIN 25.0 통계프로그램을 이용하여 t-test, ANOVA, Pearson Correlation, Multiple Linear Regression으로 분석하였다. COVID-19 상황에서 지역거점병원 간호사의 직무만족도에 유의한 설명력을 갖는 요인은 자기효능(t=3.003, p=.003), G 지역거점병원(t=2.739, p=.007), 직무부담감(t=-4.291, p<.001)이었고, 이들 요인의 결정계수인 R² 은 .441로 44.1%의 설명력을 보여주었다. 결론적으로 COVID-19 상황에서 지역거점병원 간호사의 직무만족도를 높이기 위해서는 자기효능을 증진시키는 융합 프로그램의 개발과 직무부담감을 낮추는 정책적 지원이 필요하다.

• Journal of Preventive Medicine and Public Health
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• 제57권2호
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• pp.128-137
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• 2024

Objectives: This study was conducted to characterize the symptoms, mental health, quality of life (QoL), and associated factors following the coronavirus disease 2019 (COVID-19) infection. Methods: This cross-sectional study included 394 participants previously infected with COVID-19 in Ho Chi Minh City, Vietnam. Mental health was assessed using the 21-item Depression, Anxiety, and Stress Scale (DASS-21). Participants self-reported health-related QoL was measured with the EuroQol 5-Dimension 5-Level (EQ-5D-5L) scale. Results: Among the participants, 76.4% reported experiencing at least one symptom following COVID-19 infection. The most common symptoms were fatigue (42.1%), cognitive dysfunction (42.9%), and hair loss (27.9%). According to the DASS-21 results, the proportions of depression, anxiety, and stress were 28.7%, 26.4%, and 20.6%, respectively. The mean scores on the EQ-5D-5L and the EuroQol Visual Analog Scale were 0.94±0.11 and 84.20±13.11, respectively. Regarding QoL issues, the highest proportion of participants (32.7%) reported experiencing anxiety or depression, followed by pain or discomfort (25.4%). Multivariable logistic regression analysis revealed that factors associated with the presence of symptoms following COVID-19 infection included female (odds ratio [OR], 2.84; 95% confidence interval [CI], 1.65 to 4.91) and having QoL issues (OR, 3.25; 95% CI, 1.71 to 6.19). Conclusions: The study investigated the prevalence rates of various symptoms following COVID-19 infection. These findings underscore the need to prioritize comprehensive care for individuals recovering from COVID-19 and to implement strategies to mitigate the long-term impact of the disease on mental health and QoL.

• 한국항공운항학회지
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• 제28권4호
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• pp.164-170
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• 2020

Recently, the aviation industry faced a major crisis due to the impact of COVID-19. However, despite the sluggish passenger transportation, the cargo transportation sector is relatively maintained or increasing depending on the item. In this study, we will look at the trends before and after COVID-19, focusing on the cargo export field, which is a concern of the aviation industry. First, it analyzes the entire air cargo and then analyzes the trends of each item and country in detail. In particular, it examines the process of changes in air transport costs, which increased significantly immediately after COVID-19, and conducts future trends and prospects in the cargo export field. As a result of the study, some characteristics of air cargo exports before and after COVID-19 were found in an analysis by item and country, and transportation costs varied according to route distance.

• 대한소아치과학회지
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• 제50권4호
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• pp.452-468
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• 2023

This study aims to investigate changes in dental service use among pediatric patients during the COVID-19 pandemic. The analysis was performed by collecting information about the number of visits, age, gender, diagnoses, and treatments for patients at the Pediatric Dentistry Department of Seoul National University Dental Hospital from January 2017 to December 2022. Compared with the period from 2017 to 2019, the total number of visits decreased during the COVID-19 pandemic, with a substantial decline in 2020. Patients in all age groups, except those aged 10 - 14, experienced decreased visits, and there was no significant gender difference. Z29.8 (need for other specified prophylactic measures) declined in all age groups, especially among those aged 0 - 4, except for those 20 years and older. K02.1 (caries of dentine) was sought by the age groups in the following order: 10 - 14, 15 - 19, 5 - 9, and 0 - 4 years, with the most significant decrease in the 0 - 4 years age group compared to others. K07.4 (malocclusion, unspecified) decreased in younger groups aged 9 and below but increased in older groups aged 10 and above. During the period from 2020 to 2022, preventive, restorative, pulp, and trauma treatments decreased, but surgical and orthodontic treatments increased compared with the previous three years. The use of sedation decreased and general anesthesia increased during COVID-19 compared to pre-pandemic. This study describes the impact of the COVID-19 pandemic on pediatric dentistry, making it a valuable reference for future pandemics.