• Korean Journal of Health Education and Promotion
• /
• v.31 no.4
• /
• pp.73-92
• /
• 2014

Objectives: To provide basic data needed to develop national physical activity policy, this study was examined to identify the relationship among physical inactivity, physical activity, and chronic diseases. Methods: I have reviewed articles and research reports in relation to physical activity, health, and chronic disease published in national and international since 2005 through PubMed, RISS, and KISS. Results: physical activity should be the priority of public health for the prevention and management of chronic diseases as following reasons. 1) Prevalence of physical inactivity has been continuously increased. 2) There were strong evidences that sufficient physical activity could prevent and treat dozens of chronic diseases. Conclusions: Both central and local governments need to make the amount of physical activity to be increased by providing information and establishing a physical activity-friendly environment. Also, the local public health centers and the primary medical institutions are institutionally needed to counsel and prescribe every patient's exercise program at every visit.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.10 no.1
• /
• pp.185-208
• /
• 1997

A Literatual Study on the external treatment of eye diseases, the result were as follows. 1. The external treatment of eye diseases used eyedrops(點,滴), steam bath(熏), washing(洗), plaster(敷). 2. Eyedrops used filterated decoction. 3. Eye diseases used Bomeolum(永片), Coptidis Rhiwma(黃連), Angelicae gigantis Radix(當歸) with clearing away heat and toxic materials, clearing away swelling, pain, ithing and convulsion, clearing away nebula 4. Eye diseases used B-1(晴明), B-2(찬竹), Tae-Yang(太陽), S-1(承泣), G-1(瞳子료), S-2(四白), TE-23(絲竹空), Eo-Yo(魚腰), G-14(陽白), Gu-Hu(球後), G-20(風池), B-18(肝兪), LI-4(合谷), Liv-3(太衡, B-23(腎兪), G-37(光明), Liv-2(行間), GV-23(上星), and S-36(足三里).

• Genomics & Informatics
• /
• v.11 no.4
• /
• pp.224-229
• /
• 2013

Receptor for advanced glycation endproducts (RAGE) is a multi-ligand receptor that is able to bind several different ligands, including advanced glycation endproducts, high-mobility group protein (B)1 (HMGB1), S-100 calcium-binding protein, amyloid-${\beta}$-protein, Mac-1, and phosphatidylserine. Its interaction is engaged in critical cellular processes, such as inflammation, proliferation, apoptosis, autophagy, and migration, and dysregulation of RAGE and its ligands leads to the development of numerous human diseases. In this review, we summarize the signaling pathways regulated by RAGE and its ligands identified up to date and demonstrate the effects of hyper-activation of RAGE signals on human diseases, focused mainly on renal disorders. Finally, we propose that RAGE and its ligands are the potential targets for the diagnosis, monitoring, and treatment of numerous renal diseases.

• Journal of Oriental Neuropsychiatry
• /
• v.24 no.4
• /
• pp.373-384
• /
• 2013

Objectives: The purpose of this study is to understand the cognition of the initiation of diseases of North Korean refugees in South Korea. Methods: 9 North Korean refugees hospitalized in Oriental Neuropsychiatry of National Medical Center participated in the interview. The statements were analyzed by using the phenomenological research methodology and Giorgi's analytical method, in particular, was applied. Results: A total of 4 categories and 15 sub categories were derived from the participants' descriptions. North Korean refugees who thought their diseases have begun while living in North Korea coming to South Korea, have fire disease because of the strict social system, limitations imposed on their actions, and the violence of their husbands. And who thought during escaping from North Korea, have anxiety about being killed, found and transferred to North Korea. They also suffered from a sense of guilt towards their family who were left behind as well as from depression. Consequently, they thought their skeletal diseases have begun during this period. Who thought during their period in Korea, their diseases like fire disease and depression have been worsen because of unfamiliar circumstances and doctors who said their problems had been caused by psychiatric disorder. Nevertheless, they did their jobs, felt happy and had a will to be cured thingking possibilities of overcoming diseases. Conclusions: These results suggest that various factors during different periods in the life of North Korean refugees could have an effect on their present diseases.

• Environmental Analysis Health and Toxicology
• /
• v.27
• /
• pp.6.1-6.8
• /
• 2012

Objectives: Childhood allergic diseases are a major concern because they lead to a heavy economic burden and poor quality of life. The purpose of this study was to investigate the prevalence of childhood atopic dermatitis, asthma, allergic rhinitis, and the comorbidity of allergic diseases in Seoul, Korea. Methods: We conducted a cross-sectional survey between May and October 2010 to evaluate the prevalence of childhood allergic diseases, including atopic dermatitis, asthma, and allergic rhinitis, using a questionnaire from the International Study of Asthma and Allergies in Childhood group. Each questionnaire was completed by the parent or guardian of a child. Results: In the 31,201 children studied, the prevalence of atopic dermatitis symptoms in the past 12 months was 19.3% in children 0 to 3 years of age, 19.7% in children 4 to 6 years of age, 16.7% in children 7 to 9 years of age, and 14.5% in children 10 to 13 years of age (p for trend < 0.001). The prevalence of asthma in these age groups was 16.5%, 9.8%, 6.5%, and 5.4%, respectively (p for trend < 0.001). The prevalence of allergic rhinitis in these age groups was 28.5%, 38.0%, 38.5%, and 35.9%, respectively (p for trend = 0.043). The percentage of subjects with both atopic dermatitis and asthma, both asthma and allergic rhinitis, or both atopic dermatitis and allergic rhinitis was 2.5%, 4.7%, and 8.7%, respectively. The prevalence of comorbid allergic diseases decreased with age (p for trend < 0.001). Conclusions: Our study revealed that the prevalence of some allergic diseases, such as atopic dermatitis and asthma, was relatively high in very young children and that all of the principal allergic diseases in children often co-exist.

• Korean Journal of Veterinary Service
• /
• v.41 no.4
• /
• pp.221-228
• /
• 2018

Rumen cannulation is used for nutritional and microbiological research, clinical diagnosis, and rumen component transfaunation. However, the cannulation procedure can affect parameters such as complete blood count findings, serum chemistry, and rumen fluid pH. The objective of this study was to evaluate the health risks related to the rumen cannulation procedure over a 1-month period. We did not identify significant differences in red blood cell numbers or morphologies between pre- and postoperative timepoints. Moreover, no inflammation or infection was detected. Despite the absence of apparent clinical signs after surgery, serum chemistry results revealed changes in blood urea nitrogen levels and the activities of liver enzymes, including aspartate transaminase, lactate dehydrogenase, and creatinine kinase, from postoperative days 1 to 14. Rumen fluid pH, as measured from samples collected via an orogastric tube, was slightly increased after a preoperative fasting period and on postoperative day 1 but decreased thereafter from postoperative day 4, indicating a minor influence of cannulation surgery on ruminal fluid pH. This is the first study to evaluate hematological parameters and rumen pH before and after rumen cannulation surgery in Hanwoo cattle. Further research is required to better elucidate the potential effects of rumen cannulation surgery on animal health.

• The korean journal of orthodontics
• /
• v.52 no.4
• /
• pp.268-277
• /
• 2022

Objective: Poor experience with Invisalign treatment affects patient compliance and, thus, treatment outcome. Knowing the potential discomfort level in advance can help orthodontists better prepare the patient to overcome the difficult stage. This study aimed to construct artificial neural networks (ANNs) to predict patient experience in the early stages of Invisalign treatment. Methods: In total, 196 patients were enrolled. Data collection included questionnaires on pain, anxiety, and quality of life (QoL). A four-layer fully connected multilayer perception with three backpropagations was constructed to predict patient experience of the treatment. The input data comprised 17 clinical features. The partial derivative method was used to calculate the relative contributions of each input in the ANNs. Results: The predictive success rates for pain, anxiety, and QoL were 87.7%, 93.4%, and 92.4%, respectively. ANNs for predicting pain, anxiety, and QoL yielded areas under the curve of 0.963, 0.992, and 0.982, respectively. The number of teeth with lingual attachments was the most important factor affecting the outcome of negative experience, followed by the number of lingual buttons and upper incisors with attachments. Conclusions: The constructed ANNs in this preliminary study show good accuracy in predicting patient experience (i.e., pain, anxiety, and QoL) of Invisalign treatment. Artificial intelligence system developed for predicting patient comfort has potential for clinical application to enhance patient compliance.

• The Korean journal of internal medicine
• /
• v.39 no.4
• /
• pp.680-690
• /
• 2024

Background: To evaluate the effectiveness of Korean Red Ginseng (KRG) in managing fatigue in Korean patients with rheumatic diseases Methods: Patients were randomly assigned to KRG (2 g/day, n = 60) or placebo (n = 60) groups for 12 weeks of blind phase and then open-label KRG from weeks 12 to 24 (placebo-KRG, continuous-KRG). The primary outcome was the improvement rate in fatigue, defined by an increase in Functional Assessment of Chronic Illness Therapy (FACIT)-Fatigue scores at 12 weeks. Secondary outcomes included changes in FACIT-Fatigue and fatigue visual analog scale (VAS) between 0 and 12 weeks and those changes in both indices at 24 weeks. Results: The study enrolled 120 patients (Sjogren syndrome [n = 53], rheumatoid arthritis [n = 43], or both diseases [n = 24]). The mean age was 50.9 ± 11.6 years, with 97.5% being female. Baseline characteristics were similar between the two groups. The improvement rate in FACIT-Fatigue after 12 weeks was higher in the KRG group than in the placebo group, but the difference was statistically insignificant (38.3% vs. 26.7%, p = 0.242). Improvement in fatigue was observed in both groups by increases in FACIT-F (4.6 vs. 4.0) and reductions in fatigue VAS (-16.0 vs. -12.2) scores at 12 weeks. The most frequently reported adverse events during KRG use were pruritus and urticarial, with no significant difference between the two groups. Conclusions: Both KRG and placebo groups showed significant reductions in fatigue. KRG treatment for 24 weeks did not reduce fatigue symptoms more than the placebo in patients with rheumatic diseases.

• Journal of the Korea Convergence Society
• /
• v.12 no.4
• /
• pp.95-103
• /
• 2021

This study was aimed to investigate the education needs for prevention and control of infectious diseases by lifecycle based on age group and to provide the fundamental data to develop the educational programs. A research was conducted with 328 adults over 19 years old for a month of February 2021 through online and mobile survey by Gallup Korea. Research contents include the general characteristics, personal hygiene practices related to infection, perceived risks related to infection, importance and level of knowledge on infectious diseases, and education needs for prevention and control of infectious diseases. For the research data analysis, PASW Statistics Ver 20.0 was used as a statistical program. Ranks from analysis upon conversion as the formula of Borich needs to sum up with importance and knowledge level showed first (Borich 3.11) with treatments for infectious diseases; second (Borich 2.15) with process in case of suspicion and diagnosis of infectious diseases; third (Borich 1.75) with transmission routes of infectious diseases; fourth (Borich 1.73) with preventive ways of infectious diseases; fifth (Borich 1.50) with diagnostic and test methods of infectious diseases; sixth (Borich 1.45) with characteristics of infectious diseases; and seventh (Borich1.38) with main symptoms of infectious diseases. It is anticipated that development of educational programs applying education needs for prevention and control of infectious diseases in this research can contribute to enhance the physical health, mental health, and psychological well-being of the subjects.

• Journal of Sasang Constitutional Medicine
• /
• v.23 no.4
• /
• pp.445-457
• /
• 2011

1. Purpose Lee Je-Ma had continued to revise "Donguisusebowon" by adding the contents of the Symptomatic-pharmacology(病證藥理論) on Soeumin, Soyangin and Taeeumin to it from the first establishment of the old version in 1894 to 1900.(new version). This paper tries to find out the contents and meaning of the Discourse on the Constitutional Symptoms and Diseases(病證論) between the old version and new version and what the Discourse on the Constitutional Symptoms and Diseases affected the Theory of Eight Constitution created in subsequent years. 2. Methods I classified the Discourse on the Constitutional Symptoms and Diseases in "DongYiSuseBowon" into old version and new version and tried to find out the Theory of Eight morbidities(8病證論) which is the predecessor of the Theory of Eight Constitution, before reviewing their relation. 3. Conclusions 1) The Discourse on the Constitutional Symptoms and Diseases in the old version specify that the externally sensed diseases are caused by the deep sediment of nature(性) and that the internally touched diseases are caused by the violent activities of emotion(情). In addition, it said that all diseases are caused by the specific characteristics of patient's smaller internal organs(偏小之臟). But in new version, the diseases were understood through the concept Exterior, Interior, Heat and cold(表裏寒熱). The new version said that the diseases may be caused not only the specific characteristics of patient's smaller organs but also by bigger organs(偏大之臟). 2) The Theory of Eight Constitution was derived from the Theory of Eight morbidities, in which all kinds of human diseases are caused by 8 disease-orgin organ and that the diseases therefore can be classified into 8 morbidities. The Theory of Eight morbidities reorganized the Discourse on the Constitutional Symptoms and Diseases in "DongYiSuseBowon" by classifying them into first morbidity and second morbidity. 3) The Discourse on the Constitutional Symptoms and Diseases in "DongYiSuseBowon" has decisively affected the creation of the Theory of Eight morbidities which is the predecessor of the Theory of Eight Constitution. The Theory of Eight morbidities may be deemed another interpretation of the Discourse on the Constitutional Symptoms and Diseases in "DongYiSuseBowon". As the Theory of Eight morbidities put emphasis on the genetic characteristics, the Theory of Eight Constitution stating that Eight morbidities are caused by different specific constitution was derived.