• Journal of IKEEE
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• v.19 no.3
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• pp.392-399
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• 2015

This paper proposes a unified $4{\times}4$ transform architecture for HEVC and VP9 codec to reduce hardware size. It performs HEVC $4{\times}4$ IDCT, HEVC $4{\times}4$ IDST, VP9 $4{\times}4$ IDCT, and VP9 $4{\times}4$ IADST in a unified hardware. HEVC $4{\times}4$ IDCT and VP9 $4{\times}4$ IDCT have same IDCT computation except for the scales of coefficients. Similarly, HEVC $4{\times}4$ IDST and VP9 $4{\times}4$ IADST have same IDST computation except for the scales of coefficients. Furthermore, IDCT and IDST have quite a lot of similarity, so they can share some hardwares in common. So the proposed hardware performs all 4 operations in a unified hardware, where each operation has its own multiplication coefficients with shared butterfly adders. The synthesized block in 0.18 um technology is 6,679 gates, and the gate count is reduced by 25.3% in comparison with conventional designs.

• Journal of Life Science
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• v.24 no.10
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• pp.1144-1150
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• 2014

The eIF4E protein is the key regulator of translation initiation. The interaction of eIF4E with eIF4G triggers the translation of mRNA, and several proteins interrupt this association to modulate translation. Human 4E-T is one of the eIF4E-binding partners that represses the translation of bound mRNAs, and it is involved in the transport of eIF4E to processing bodies (P-bodies). Although Clast4, the mouse homolog of human 4E-T, might play critical roles in the regulation of translation, its properties are not well known. In this report, we deciphered the properties of Clast4 by determining its phosphorylation state, binding to eIF4E, and effects of overexpression on cell proliferation. Clast4 was phosphorylated by protein kinase A (PKA) in vivo on several residues of its amino terminus. Nevertheless, the PKA phosphorylation of Clast4 appeared to have no effect on either its eIF4E-binding ability or localization. Clast4 interacted with eIF4E1 and CPEB. The conserved eIF4E-binding sequence in Clast4, $YXXXXL_{\phi}$, was important for binding eIF4E1A but not eIF4E1B. Similar to that of another well-known eIF4E regulator, the eIF4E binding protein (4E-BP), the overexpression of Clast4 decreased cell proliferation. These results suggest that Clast4 acts as a global translation regulator in cells.

• Membrane Journal
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• v.26 no.2
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• pp.108-115
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• 2016

This study is to evaluate the performance of draw solutions in the water reuse of sewage discharge water using fertilizer drawn forward osmosis. Feed water used in all experiments was the effluent from secondary sedimentation tank in activated sludge process. Considering osmotic pressure, solubility, and pH, $NH_4H_2PO_4$, KCl, $KNO_3$, $NH_4Cl$, $(NH_4)_2HPO_4$, $NH_4NO_3$, $NH_4HCO_3$, and $KHCO_3$ were screened from a comprehensive lists of fertilizer. Their performances were evaluated in terms of water permeate flux and reverse solute flux. KCl showed the highest average water flux followed by $NH_4Cl$, $NH_4NO_3$, $KNO_3$, $KHCO_3$, $NH_4HCO_3$, $NH_4H_2PO_4$, and $(NH_4)_2HPO_4$. Using KCl as draw solution, the average water permeate flux was 13.49 LMH. There was no big difference in osmotic pressure between the effluent from secondary sedimentation tank and deionized water. $NH_4H_2PO_4$ showed the lowest reverse solute flux followed by $NH_4Cl$, $(NH_4)_2HPO_4$, $KNO_3$, $NH_4HCO_3$, and $NH_4NO_3$. Using $NH_4H_2PO_4$ as draw solution, the reverse solute flux was $4.96{\times}10^{-3}mmol/m^2{\cdot}sec$.

• YAKHAK HOEJI
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• v.46 no.5
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• pp.313-319
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• 2002

Synthesis of 7$\beta$-[(Z)-2-(2-aminothiazol-4-yl)-2-(1-carboxy-1-methylethoxyimino)acetamido]-3-[[(3S, 5S)-5-[4-phenyl-5-(4-methylphenyl or 2-thiophenyl)-4H-l, 2, 4- triazol-3-yl]thiomethylpyrrolidin-3-yl]]thiomethyl-3-cephem-4-carboxylic acids (7a, 7b) were described. (2S, 4S)-4-acethylthio-2-[4-phenyl-5-(4-methylphenyl or 2-thiophenyl)-4 H-1, 2, 4-triazol-3-yl]thiomethyl-1-tert-butoxycarbonylpyrrolidines (4a, 4b) were prepared from trans-4-hydroxy-L-proline with (2S, 4R)-absolute configuration as starting material. 4-Phenyl-5-(4-methylphenyl or 2-thiophenyl)-4 H-l, 2, 4-triazol-3-thiols (2a, 2b) were prepared from p-toluic anhydride and 2-thiophene carboxylic acid hydrazide, respectively. p-Methoxybenzyl 7$\beta$-(Z)-2-(2-for-mamidothiazol-4-yl)-2-(1-tert-butoxycarbonylisopropylimino]acetamido-3-[[ (3S, 5S)-5-[4-phenyl-5-(4-methylphenyl or 2-thio phenyl)-4H-1, 2, 3-triazol-3-yl]thiomethyl-1- tert-butoxycarbonylpyrrolidin-3-yl]]thiomethyl-3-cephem-4-carboxylates (6a, 6b) were achieved by using p-methoxybenzyl ]7P-(Z)-2-(2-formamidothiazol-4-yl)-2-(tert-butoxycarbonylisopropylimino] acetamido-3-chloromethyl-3-cephem-4-carboxylate (5) and (2S, 4S)-4-acethylthio-2-[4-phenyl-5-(4-methyl phenyl or 2-thiophenyl)-4H-1, 2, 4-triazol-3-yl]thiomethyl-1-tert-butoxycarbonyl pyrrolidines (4a, 4b). Removal of formyl, Boc, and p-methoxybenzyl protecting groups were carried out by triflu oroacetic acid and anisole to give the target compounds.

• Archives of Pharmacal Research
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• v.13 no.4
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• pp.310-313
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• 1990

Hantzsch synthesis of 5-formyluracil (1) methyl acetoacetate (2) and methyl 3-aminocrotonate (3) gave 2, 6-dimethyl-4-(2, 4-dioxo-5-pyrimidy)-1, 4-dihydropyridine-3, 5-dicarboxylic acid dimethylester (4a) in 54.6 yield. As the same procedure, 1, 3-dimethyl-5-formyl-uracil (6) gave 2, 6-dimethyl-4-(1, 3-dimethyl-2, 4-dioxo-5-pyrimidyl)-1, 4-dihydropyridine-3, 5-dicarboxylic acid dimethyl easter (7a) IN 52.2% yield. 4a was methylated to afford 7a also in 52% yield.

• Korean Journal of Microbiology
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• v.34 no.4
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• pp.248-253
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• 1998

Bacteriophage N4, a lytic phage specific for Esherichia coli K12 strain encodes single-stranded DNA-binding protein, N4SSB (bacteriophage N4-coded single-stranded DNA-binding protein). N4SSB protein is originally identified as a protein required for N4 DNA replication. N4SSB protein is also required for N4 late transcription, which is catalyzed by E. coli ${\sigma}^{70}$ RNA polymerase. N4 late transcription does not occur until N4SSB protein is synthesized. Recently it is reported that N4SSB protein is essential for N4 DNA recombination. Therefore N 4SSB protein is a multifunctional protein required for N4 DNA replication, late transcription, and N4 DNA recombination. In this study, a variety of mutant N4SSB proteins containing internal deletions or substitutions were constructed to define and characterize domains important for N4 DNA replication, late transcription, and N4 DNA recombination. Test for the ill vivo activity of these mutant N4SSBs for N4 DNA replication, late transcription, and N4 DNA recombination was examined. The results suggest that C-terminal 7 amino acid residues are important for the activity of N4SSB. Three lysine residues, which are contained in this region play important roles on N4SSB activity.

• Journal of the Korean Crystal Growth and Crystal Technology
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• v.14 no.4
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• pp.135-139
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• 2004

The layered organic-inorganic hybrid compounds($C_6H_5CH_2NH_3)_2CuCl_4$ and ($NH_3C_6/H_4C_2H_4_6/H_4NH_3)CuCl_4$ have been directly synthesized. From the X-ray diffraction data and the organic guest size, the orientation of the intercalated organic amine was determined. The inorganic sheets consist of $CuCl_4^{2-}$layers of comer-sharing octahedra copper chloride. The protonated organic amine was intercalated into the $CuCl_4^{2-}$layers with bilayer structure for ($C_6H_5CH_2NH_3)_2CuCl_4$ and monolayer structure for ($NH_3C_6/H_4C_2H_4_6/H_4NH_3)CuCl_4$.

• Textile Coloration and Finishing
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• v.9 no.1
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• pp.44-49
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• 1997

Recent investigation and developments of A. Iqbal on diketo-pyrrolo-pyrrole (DPP) pigments has prompted us to synthesize and close observation of a few properties of these molecules. Described are synthesis, via 1-phenyl-2-ethoxycarbonyl-5-pyrrolinone intermediate, of asymmetric derivatives such as 1,4-Diketo-3-(4-chlorophenyl)-6-phenyl-pyrrolo-(3,4c)-pyrrole (4), 1,4-Diketo-3-(4-bromophenyl)-6-phenybpyrrolo-(3,4c)-pyrrole (5), 1,4-Diketo-3-(3-cyanophenyl)-6-phenyl-pyrrolo-(3,4c)-pyrrole (6), 1,4-Diketo-3-(4-cyanophenyl)-6-phenyl-pyrrolo-(3,4c)-pyrrole (7), 1,4-Diketo-3-(4-pyridyl)-6-phenyt-pyrrolo-(3,4c)-pyrrole (8), 1,4-Diketo-3-(3-pyridyl)-6-phenyl-pyrrolo-(3,4c)-pyrrole (9), 1,4-Diketo-3-(2-pyridyl)-6-phenyl-pyrrolo-(3,4c)-pyrrole (10), 1,4-Diketo-3-($\beta$-naphthyl)-6-phenyl-pyrrolo-(3,4c)-pyrrole (11), and UV-Vis absorption spectrum of the above compounds. Results from calculation of their absorption maxima using PISYSTEM are also described.

• Korean Journal of Microbiology
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• v.13 no.3
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• pp.101-108
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• 1975

Physiological effects of 2,4-D on the growth of Chlorella ellipsoidea were investigated culturing the alage in the MN4 media containing 0. $10^{-4}/M$ and $4<\times}10^{-4}M$ 2,4-D. During 6 days culture were taken to analysis with respect to overall growth, photosynthesis, respiration and chemical composition. Results obtained from the experiment were as follows : 1) The growth of chlorella was increased at $10^{-4}M$ and decreased at $4{\times}10^{-4}M$ of 2,4-D concentrations 2) At $10^{-4}M$ pf 2,4-D cpncentration, the activity of photosynthesis enhanced relative to contro. while at $4{\times}10^{-4}M$ it was not changed. In both concentrations, however, the rate of respiration was down from the control. 3) At $10^{-4}M$ 2,4-D, the concentration of carbondrate metabolites was not changed relative to control, while significant increase in the concentrations of proteins and nucleic acids was observed. On the other hand at $4{\times}10^{-4}M$ of 2,4-D concentrations, all the metabolites including carbohydrates, proteins and nucleic acids were descreased. 4) It is concluded that 2,4-D at $10^{-4}M$ concentration accelerates the growth of chlorella by promoting the activities of photosynthesis and biosynthesis of proteins and nucleic acids.

• YAKHAK HOEJI
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• v.13 no.2_3
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• pp.62-66
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• 1969

Ten new N$^{4}$-furoylsulfonamides were synthesized such as N$^{4}$-furoyl-N$^{1}$-(4,6-dimethyl-2-pyrimidinyl) sulfanilamide (I), N$^{4}$-furoylsulfanilamide (II), N$^{4}$-furoyl-N$^{1}$-(2,6-dimethoxy-4-pyrimidinyl) sulfanilamide (III), N$^{4}$-furoyl-N$^{1}$-(4-methyl-2-pyrimidinyl) sulfanilamide (IV), N$^{4}$-furoyl-N$^{1}$-(6-methoxy-3-pyridazinyl) sulfanilamide (V), N$^{4}$-furoyl-N$^{1}$-2-pyrimidinylsulfanilamide (VI), N$^{4}$-furoyl-N$^{1}$-(3,4-dimethyl-5-isoxazolyl) sulfanilamide (VII), N$^{4}$-furoyl-N$^{1}$-2-thiazoilysulfanilamide (VIII), N$^{4}$-furoyl-N$^{1}$-(5-methoxy-2-pyrimidinyl) sulfanilamide (IX) and N$^{4}$-furoyl-N$^{1}$-(2,6-dimethyl-4-pyrimidinyl) sulfanilamide (X). They were obtained by the action of N$^{1}$-(4,6-dimethyl-2-pyrimidinyl) sulfanilamide, N$^{1}$-(2,6-dimethoxy-4-pyrimidinyl) sulfanilamide, N$^{1}$-(4-methyl-2-pyrimidinyl) sulfanilamide, N$^{1}$-(6-methoxy-3-pyridazinyl) sulfanilamide, N-2-pyrimidinyl sulfanilamide, N$^{1}$-(3,4-dimethyl-5-isoxazolyl) sulfanilamide, N$^{1}$-2-(thiazolysulfanilamide), N$^{1}$-(5-methoxy-2-pyrimidinyl) sulfanilamide and N$^{1}$-(2,6-dimethyl-4-pyrimidinyl) sulfanilamide with furoyl chloride in 4% NaOH solution. Of the above ten compounds, N$^{4}$-furoylsulfathiazole exhibited a good antibacterial action against Staphylococeus aureus and Escherichia coli.