• Title/Summary/Keyword: 3SPR

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Fabrication of Multicomponent Protein Microarrays with Microfluidic Devices of Poly(dimethylsiloxane)

  • Jeon, Se-Hoon;Kim, Ui-Seong;Jeon, Won-Jin;Shin, Chee-Burm;Hong, Su-Rin;Choi, In-Hee;Lee, Su-Seung;Yi, Jong-Heop
    • Macromolecular Research
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    • v.17 no.3
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    • pp.192-196
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    • 2009
  • Recently, the multi-screening of target materials has been made possible by the development of the surface plasmon resonance (SPR) imaging method. To adapt this method to biochemical analysis, the multi-patterning technology of protein microarrays is required. Among the different methods of fabricating protein microarrays, the microfluidic platform was selected due to its various advantages over other techniques. Microfluidic devices were designed and fabricated with polydimethylsiloxane (PDMS) by the replica molding method. These devices were designed to operate using only capillary force, without the need for additional flow control equipment. With these devices, multiple protein-patterned sensor surfaces were made, to support the two-dimensional detection of various protein-protein interactions with SPR. The fabrication technique of protein microarrays can be applied not only to SPR imaging, but also to other biochemical analyses.

Design of surface plasmon resonance sensors using evolution algorithm (진화알고리즘을 이용한 표면플라즈몬 공명센서의 설계)

  • Jung, Jae-Hoon;Kim, Min-Wook
    • Proceedings of the KIEE Conference
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    • 2006.07c
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    • pp.1615-1616
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    • 2006
  • 본 논문에서는 표면 플라즈몬 공명(Surface Plasmon Resonance) 센서의 여러 파라미터를 동시에 만족시키는 설계기법을 제시하였다. 설계 파라미터는 반사광 dip의 3dB bandwidth와 dip의 깊이이고 목적함수는 해석치와 목표치의 차이 벡터의 norm으로 정의하였다. 설계 변수는 박막된 각 금속 충의 두께로 하였고 SPR 센서의 스펙트럼을 해석하기 위해 광학 어드미턴스 기법을 이용하였다. 최적화 기법은 (1+1) 진화 알고리즘을 사용하였다. 설계방법을 3층 구조의 SPR 센서에 적용하여 최적 설계한 파라미터는 초기값에 비해 3dB bandwidth는 4.8nm, dip의 깊이는 1.1dB 향상되었다.

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Convergence studies for Enriched Free Mesh Method and its application to fracture mechanics

  • Matsubara, Hitoshi;Yagawa, Genki
    • Interaction and multiscale mechanics
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    • v.2 no.3
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    • pp.277-293
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    • 2009
  • The Enriched Free Mesh Method (EFMM) is a patch-wise procedure in which both a displacement field on an element and a stress/strain field on a cluster of elements connected to a node can be defined. On the other hand, the Superconvergent Patch Recovery (SPR) is known to be an efficient post-processing procedure of the finite element method to estimate the error norm at a node. In this paper, we discuss the relationship between solutions of the EFMM and those of the SPR through several convergence studies. In addition, in order to solve the demerit of the smoothing effect on the fracture mechanics fields, we implement a singular stress field to a local patch in the EFMM, and its effectiveness is investigated.

정신위생분야에 있어서의 시청각자료

  • Kim, Yeong-Gwi
    • KLA journal
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    • v.24 no.3
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    • pp.2-10
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    • 1983
  • Brigitte L. Kenney는 Colorado주 Golden에 있는 INFOCON, Inc.,의 사장이다. 이 논문은 Kenney, Brigitte L., 'Audiovisuals in mental health,' Library Trends, Vol.30, No.4(Spr. 1982), pp.591-611을 번역한 것이다.

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Combustive Characteristics of Wood Specimens Treated with Alkylenediaminoalkyl-Bis-Phosphonic Acids (알킬렌디아미노알킬-비스-포스폰산으로 처리된 목재의 연소특성)

  • Chung, Yeong-Jin
    • Fire Science and Engineering
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    • v.27 no.6
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    • pp.57-63
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    • 2013
  • This study was performed to test the combustive properties of Pinus rigida specimens treated with piperazinomethyl-bis-phosphonic acid (PIPEABP), methylpiperazinomethyl-bis-phosphonic acid (MPIPEABP), and N,N-dimethylethylene-diaminomethyl-bis-phosphonic acid (MDEDAP). Pinus rigida Plates were painted in three times with 15 wt% alkylenedi-aminoalkyl-bis-phosphonic acid solutions at the room temperature. After drying specimen treated with chemicals, combustive properties were examined by the cone calorimeter (ISO 5660-1). It was indicated that the specimens treated with chemicals showed the later time to peak mass loss rate ($TMLR_{peak}$) = (315~420) s than that of virgin plate by reduc-ing the burning rate except for $TPMR_{peak}$ (280 s) treated with DMDAP. In adition, the specimens treated with chemicals showed both the higher total smoke release rate (TSRR) (407.3~902.0) $m^2/m^2$ and $CO_{mean}$ production (407.3~902.0) $m^2/m^2$ than those of virgin plate. Especially, for the specimens treated with PIPEABP, 1st-smoke production rate (1st-SPR) (0.1250~0.1297) g/s was lower than that of virgin plate, while the 2nd-SPR (0.183 g/s) was higher. Thus, It is supposed that the combustion-retardation properties were improved by the partial due to the treated alkylenediaminoalkyl-bis-phos-phonic acids in the virgin Pinus rigida.

A Feasibility Study on a Subsurface-Penetrating Radar for Nondestructive Testing of Wooden Architectures : FDTD Simulation and Laboratory Measurement (목조 건축물의 비파괴 검사를 위한 표면하부 탐사 레이더의 적용 가능성 검토 : FDTD 모의계산과 실험 측정)

  • 현승엽;김세윤
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.13 no.8
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    • pp.790-796
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    • 2002
  • In our country, historically beautiful and significant wooden architectures are preserved as the cultural properties. For a long time, however, the architectures are often exposed to rough environmental conditions, such as weathering, insect attack, etc. This may lead to deterioration of structural integrity of the architectures. Therefore, it is necessary to diagnose wooden architectures in advance. In this paper, the possibility of a subsurface-penetrating radar(SPR) fur non-destructive testing(NDT) of wooden architectures is investigated by using the three-dimensional finite-difference time-domain(FDTD) simulation and actual laboratory measurement.

An Application of Surface Plasmon Resonance to Evaluation of Quality Parameters of Soybean Oil during Frying

  • Gil, Bo-Gim;Chang, Young-Ki;Cho, Yong-Jin
    • Food Science and Biotechnology
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    • v.15 no.3
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    • pp.404-408
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    • 2006
  • Feasibility of surface plasmon resonance (SPR) method to evaluate soybean frying oil quality was evaluated. Free fatty acid value, p-anisidine value, conjugated dienoic acid content, conjugated trienoic acid content, peroxide value, iodine value, total polar compound (TPC), ratio of unsaturated fatty acid to saturated fatty acid, refractive index, dielectric constant, smoking point, and L, a, and b of Hunter color system were selected as parameters related to conventional evaluation of soybean frying oil quality. SPR scale mapped with conventional quality parameters well described free fatty acid value, conjugated dienoic acid content, dielectric constant, TPC, and b of Hunter color system, as shown by correlation and linear regression analyses.

Physicochemical Properties and Antioxidant Activities of Ssammoo added with Natural Food Colorants (천연식품 색소를 첨가한 쌈무의 이화학적 특성 및 항산화 활성)

  • Young-Hwa Jang;Ji-Hyun Kim
    • Human Ecology Research
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    • v.62 no.3
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    • pp.601-607
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    • 2024
  • In this study, the color of ssammoo was to created in an addition of gardenia powder(GPR), citron powder(CPR), strawberry powder(SPR), and actinidia arguta powder(APR), respectivery. Ssammoo was collected on the 0th, 3rd, 7th, and 14th days of stored at 5℃. The pH of the control group and ssammoo with the actinidia arguta powder was significantly lowered over time(p <.001). The acidity was significantly decreased in the case of ssammoo with actinidia arguta powder(p <.05). The sugar content of all ssammoos increased due to osmotic pressure as the ripening period increased. The L value was the highest in the control group and increased over time(p <.001). The a and b value were the highest in ssammoo with gardenia powder(p <.001). The ΔE increased until the 7th day of storage and then decreased, suggesting that there would be a change in color value of all ssammoos after the 7th day of storage. The total phenol content and DPPH radical scavenging activity was highest in ssammoo with gardenia powder. The ABTS radical scavenging activity was highest in ssammoo with strawberry powder. This study intended to contribute to increasing the intake of vegetables and fruits with high dietary fiber content by developing colored salted and pickled foods.

Active Ingredients and Antioxidant Activities of Salvia plebeia R. Br. According to Pretreatment Conditions (전처리 조건에 따른 배암차즈기(Salvia plebeia R. Br.)의 주요 성분의 함량 및 항산화)

  • Kim, Yong-Joo;Jeong, Ji-Suk;Park, No-Jin;Go, Geun-Bae;Son, Byeong-Gil
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.43 no.12
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    • pp.1948-1953
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    • 2014
  • This study examined changes in antioxidant activity as well as contents of rosmarinic acid, homoplantaginin, and luteolin, which is the main substance of Salvia plebeia R. Br. (SPR) known to have anti-inflammatory efficacy, according to drying, blanching, and fermentation conditions. Rosmarinic acid content was 16.42 mg/g upon hot-air drying and 10.19 mg/g upon hot-air drying after blanching, and there was no significant difference in the case of leaf and root freezing or cold-air drying. Rosmarinic acid content was 8.69 and 8.15 mg/g in the case of air-drying in the shade and freeze-drying, respectively, and decreased to 0.05 mg/g or undetected after fermentation. SPR processed by freeze-drying, cold-air drying in the shade, and hot-air drying showed ABTS radical scavenging ability over 98.5% at a concentration over $500{\mu}g/mL$ as well as excellent radical scavenging ability of 87.3% in the case of hot-air drying after blanching. Root showed lower ABTS radical scavenging ability than leaves. SOD-like activity was measured to be 6.1~27.8% at a concentration of $1,000{\mu}g/mL$, which was significantly difference from ABTS radical scavenging ability. As rosmarinic acid and homoplantagine, an anti-inflammatory material contained in SPR, are almost undetectable after oxidation fermentation during processing, hot-air drying after blanching or drying seems to be suitable to develop SPR as a functional substance.

A Study on the Feasibility of Win-Win Growth in Wholesale Market

  • WON, Jong-Moon
    • The Journal of Industrial Distribution & Business
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    • v.11 no.4
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    • pp.31-38
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    • 2020
  • Purpose: At a time when the distribution industry is dominated by capital and technology, win-win growth among businesses groups (BGs) in wholesale market is becoming a social issue. Therefore, through analysis of market growth, market concentration (MC) and market power (MP), we want to identify the structure of the wholesale market and the competitiveness of the BGs in terms of market share (MS), sales-profit ratio (SPR), and labor productivity (LP) to explore the possibility of win-win growth. Market situation: Wholesale and Retail sales ratio (W/S) continues to increase, which also means inefficiency in distribution channels or opportunities in wholesale markets. Wholesale sales have grown 8.3 percent annually over the past 15 years, while the number of companies and workers has declined since 2017, which is why some restructuring is believed to begin in the wholesale industry. In terms of MC and MP, the growth potential of SBG can be found in FCB, ARM, FBT and CME BTs. Methodology and data: Through ANOVA and Regression Analysis, the 2015 Economic Census Data of KOSTAT was analyzed. Results: The results of ANOVA show that statistically significant SBG has a larger MS than LBG. The SPR was not different among BGs. LP is higher for LBG than for other BGs. Regression results show that the employment weight (EW) and the company size (SC) have positive effects on the MS, but the company weight (CW) and employment size (SE) have negative effects. In the case of SPR, the CW is positive and the EW is negative. In addition, LP appears to be more positive as SC in the BGs is larger. Conclusions: Although there is sufficient potential for SBG in the wholesale market, there is a problem that needs to increase LP. Therefore, the SBG needs to restructure in terms of number of companies and SC to improve the efficiency of employment. In terms of MC and MP, the SBG looks for possibilities in FCB, ARM, FBT and CME BTs. In addition, SBG that seeks higher returns with human services rather than simple sales is found to be competitive in the HHG, MES and CME BTs.