• Title/Summary/Keyword: 3DES[2]

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Intake and Digestive Processes in the Rumen of Rams Fed with Digitaria decumbens Harvested at Four Stages of Grass Regrowth Age

  • Assoumaya, C.;Boval, M.;Sauvant, D.;Xande, A.;Poncet, C.;Archimede, H.
    • Asian-Australasian Journal of Animal Sciences
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    • v.20 no.6
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    • pp.925-932
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    • 2007
  • This study was designed to measure the effect of regrowth age of Digitaria decumbens (D. decumbens) on the intake and dynamics of digesta in the rumen of rams. Six Black-belly rams (mean liveweight: 51.6 (s.d. 0.68) kg) fitted with rumen cannulae were fed twice daily a 14-, 28-, 42- and 56-day old fresh D. decumbens successively for 4 experimental periods. The daily dry matter intake decreased curvilineary from 75.2 to 48.5 (s.e. 2.0) g/kg $BW^{0.75}$ as the age of the D. decumbens grass increased from 14 to 56 days. Dry matter intake for the first 3 h after the morning meal was 863.6, 598.3, 576.4 and 401.5 (s.e. 55.6) g for the 14-, 28-, 42- and 56-day old grasses respectively. The pool of NDF in the rumen at the end of the 3-h feeding period did not vary significantly among the four diets. Twelve hours after the beginning of the morning meal, the pool of NDF increased with the forage regrowth age. Within the total pool of NDF, the pool of large particles tended to increase with the regrowth age. It was concluded that high intake was associated with fast evacuation of NDF from the rumen. Moreover, digestion (cellulolysis) rate and degree of particle reduction by rumination are highly correlated, though speed of physical degradation of forage seems to be the driving force behind intake.

Effects of Histamine on Cultured Interstitial Cells of Cajal in Murine Small Intestine

  • Kim, Byung Joo;Kwon, Young Kyu;Kim, Euiyong;So, Insuk
    • The Korean Journal of Physiology and Pharmacology
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    • v.17 no.2
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    • pp.149-156
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    • 2013
  • Interstitial cells of Cajal (ICCs) are the pacemaker cells in the gastrointestinal tract, and histamine is known to regulate neuronal activity, control vascular tone, alter endothelial permeability, and modulate gastric acid secretion. However, the action mechanisms of histamine in mouse small intestinal ICCs have not been previously investigated, and thus, in the present study, we investigated the effects of histamine on mouse small intestinal ICCs, and sought to identify the receptors involved. Enzymatic digestions were used to dissociate ICCs from small intestines, and the whole-cell patch-clamp configuration was used to record potentials (in current clamp mode) from cultured ICCs. Histamine was found to depolarize resting membrane potentials concentration dependently, and whereas 2-PEA (a selective H1 receptor agonist) induced membrane depolarizations, Dimaprit (a selective H2-agonist), R-alpha-methylhistamine (R-alpha-MeHa; a selective H3-agonist), and 4-methylhistamine (4-MH; a selective H4-agonist) did not. Pretreatment with $Ca^{2+}$-free solution or thapsigargin (a $Ca^{2+}$-ATPase inhibitor in endoplasmic reticulum) abolished the generation of pacemaker potentials and suppressed histamine-induced membrane depolarization. Furthermore, treatments with U-73122 (a phospholipase C inhibitor) or 5-fluoro-2-indolyl des-chlorohalopemide (FIPI; a phospholipase D inhibitor) blocked histamine-induced membrane depolarizations in ICCs. On the other hand, KT5720 (a protein kinase A inhibitor) did not block histamine-induced membrane depolarization. These results suggest that histamine modulates pacemaker potentials through H1 receptor-mediated pathways via external $Ca^{2+}$ influx and $Ca^{2+}$ release from internal stores in a PLC and PLD dependent manner.

Thorea indica sp. nov. (Thoreales, Rhodophyta) from Uttar Pradesh, India

  • Necchi, Orlando Jr;Paiano, Monica O.;West, John A.;Ganesan, E. K.;Goer, Susan Loiseaux-de
    • ALGAE
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    • v.30 no.4
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    • pp.265-274
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    • 2015
  • Thorea indica sp. nov. is described from the Sai River, Uttar Pradesh, India (26°39′00.7″ N, 80°47′38.3″ E). Its classification is based on molecular sequences of the plastid-encoded RuBisCO large-subunit gene, rbcL and the barcode region of the mitochondrial encoded cytochrome c oxidase subunit 1, cox1, and morphological data. The sequence analyses confirm a new species of Thorea. The cox1 barcode sequence had 90.4-90.8% identity with Thorea sp. from Australia and Thorea hispida from Hawaii and China. Based on rbcL sequences the Indian specimen was positioned in a major clade with high support (>95 bootstrap and 0.95 posterior probability) containing two other species: T. okadae from Japan and T. hispida from the continental USA, Hawaii, the UK, and China. The divergences among these sequences were T. indica vs. T. okadae (2.8%) and T. indica vs. T. hispida (2.9-3.4%). The comparison of morphological characters of Thorea from India was not conclusive due to the inadequate descriptions in previous reports: most specimens reported as T. hispida fit within the circumscription of T. indica as described here. The previous report of T. siamensis from the Sai River is incorrect and the specimens fit within our description of T. indica. Thorea indica and T. okadae can be distinguished by minor morphometric characters and sexuality (dioecious vs. monoecious).

Influence of Bradykinin on Catecholamine Release from the Rat Adrenal Medulla

  • Lim, Dong-Yoon;Kim, Il-Hwan;Na, Gwang-Moon;Kang, Moo-Jin;Kim, Ok-Min;Choi, Deok-Ho;Ki, Young-Woo
    • The Korean Journal of Physiology and Pharmacology
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    • v.7 no.4
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    • pp.231-238
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    • 2003
  • The present study was undertaken to investigate the effect of bradykinin on secretion of catecholamines (CA) evoked by stimulation of cholinergic receptors and membrane depolarization from the isolated perfused model of the rat adrenal glands, and to elucidate its mechanism of action. Bradykinin $(3{\times}10^{-8}M)$ alone produced a weak secretory response of the CA. however, the perfusion with bradykinin $(3{\times}10^{-8}M)$ into an adrenal vein of the rat adrenal gland for 90 min enhanced markedly the secretory responses of CA evoked by ACh $(5.32{\times}10^{-3}M)$, excess $K^+$ ($5.6{\times}10^{-2}M$, a membrane depolarizer), DMPP ($10^{-4}$ M, a selective neuronal nicotinic agonist) and McN-A-343 ($10^{-4}$ M, a selective M1-muscarinic agonist). Moreover, bradykinin ($3{\times}10^{-8}$ M) in to an adrenal vein for 90 min also augmented the CA release evoked by BAY-K-8644, an activator of the dihydropyridine L-type $Ca^{2+}$ channels. However, in the presence of $(N-Methyl-D-Phe^7)$-bradykinin trifluoroacetate salt $(3{\times}10^{-8}M)$, an antagonist of $BK_2$-bradykinin receptor, bradykinin no longer enhanced the CA secretion evoked by Ach and high potassium whereas the pretreatment with Lys-$(des-Arg^9,\;Leu^9)$-bradykinin trifluoroacetate salt $(3{\times}10^{-8}M)$, an antagonist of $BK_1$-bradykinin receptor did fail to affect them. Furthermore, the perfusion with bradykinin $(3{\times}10^{-6}M)$ into an adrenal vein of the rabbit adrenal gland for 90 min enhanced markedly the secretory responses of CA evoked by excess $K^+$ $(5.6{\times}10^{-2}M)$. Collectively, these experimental results suggest that bradykinin enhances the CA secretion from the rat adrenal medulla evoked by cholinergic stimulation (both nicotininc and muscarinic receptors) and membrane depolarization through the activation of $B_2$-bradykinin receptors, not through $B_1$-bradykinin receptors. This facilitatory effect of bradykinin seems to be associated to the increased $Ca^{2+}$ influx through the activation of the dihydropyridine L-type $Ca^{2+}$ channels.

Effects of temperature and relative humidity on the sampling efficiencies of mixed organic vapors measured by diffusion monitors (확산 포집기로 공기중 혼합유기용제 포집시 온도와 상대습도가 포집효율에 미치는 영향)

  • Han, Jin gu;Roh, Young Man;Kim, Hyun Wook
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.5 no.2
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    • pp.200-211
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    • 1995
  • This study was designed to evaluate the effects of temperature and humidity on the sampling efficiency of mixed organic vapors of l,2-DCE, benzene, and MIBK by 3 different types of diffusion monitors. Independent variables used for the study were temperatures ($25^{\circ}C$, $35^{\circ}C$), humidities (30%, 80%), and vapor concentrations (low, medium, and high). In addition, vapor concentrations measured by the traditional charcoal tube method were used as reference values and were compared with those of by diffusion monitors. The results were as follows: 1. The desorption efficiencies(DE) of 1,2-DCE and benzene from charcoal tubes and from diffusion monitors ranged from 98% to 105%. In contrast, the DEs of MIBK from charcoal tubes and diffusion monitors except DM1 ranged from 71% to 85%. The DE of MIBK from DM1 was 98%. 2. No statistically significant differences of 1,2-DCE concentrations and the sampling efficiencies regardless of temperatures and humidities studied between charcoal tube and 3 diffusion monitors were found. 3. At 80% humidity, increasing frequencies of 1,2-DCE breakthrough at higher temperature and higher vapor concentration measured by charcoal tubes were observed. 4. No statistically significant difference of benzene concentrations were found between charcoal tube and diffusion monitors except DM3. The sampling efficiencies of DM3 were statistically significantly lower at all experimental conditions except the $35^{\circ}C$ and 30% humidity condition. 5. No statistically significant difference of MIBK concentrations were found between charcoal tube and diffusion monitors except DM3. The sampling efficiencies of DM3 were statistically significantly higher at higher humidity conditions regardless of temperature. Although statistically not significant, sampling efficiency of MIBK showed positive correlation with humidity while negative correlation with concentration was observed. 6. For sampling 1,2-DCE and benzene, no significant variations of concentrations among three diffusion monitors regardless of temperature and humidity conditions were found. For MIBK sampling, however, wide variations with increasing humidity among diffusion monitors were obtained. In conclusion, this study suggests that diffusion monitors will be a reasonables substitute for the traditional charcoal tubes for sampling non-polar organic vapors at temperature and humidity conditions studied. For polar organic vapors, use of an alternative desorption solution other than CS2 is recommended because of its low desorption efficiency. In addition, since variable among diffusion monitors for polar organic vapors particularly at higher humidity conditions were observed, further study is recommended of the effects of humidity on the performance of diffusion monitors.

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Complex Segregation Analysis of Total Milk Yield in Churra Dairy Ewes

  • Ilahi, Houcine;Othmane, M. Houcine
    • Asian-Australasian Journal of Animal Sciences
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    • v.24 no.3
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    • pp.330-335
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    • 2011
  • The mode of inheritance of total milk yield and its genetic parameters were investigated in Churra dairy sheep through segregation analyses using a Monte Carlo Markov Chains (MCMC) method. Data which consisted of 7,126 lactations belonging to 5,154 ewes were collected between 1999 and 2002 from 15 Spanish Churra dairy flocks. A postulated major gene was assumed to be additive and priors used for variance components were uniform. Based on 50 000 Gibbs samples from ten replicates chains of 100,000 cycles, the estimated marginal posterior means${\pm}$posterior standard deviations of variance components of milk yield were $23.17{\pm}18.42$, $65.20{\pm}25.05$, $120.40{\pm}42.12$ and $420.83{\pm}40.26$ for major gene variance ($\sigma_G^2$), polygenic variance ($\sigma_u^2$), permanent environmental variance ($\sigma_{pe}^2$) and error variance ($\sigma_e^2$), respectively. The results of this study showed the postulated major locus was not significant, and the 95% highest posterior density regions ($HPDs_{95%}$) of most major gene parameters included 0, and particularly for the major gene variance. The estimated transmission probabilities for the 95% highest posterior density regions ($HPDs_{95%}$) were overlapped. These results indicated that segregation of a major gene was unlikely and that the mode of inheritance of total milk yield in Churra dairy sheep is purely polygenic. Based on 50,000 Gibbs samples from ten replicates chains of 100,000 cycles, the estimated polygenic heritability and repeatability were $h^2=0.20{\pm}0.05$ and r=$0.34{\pm}0.06$, respectively.

Methoden Zur Beschreibung dar Unfallgeschehens des - Versuch eines Vergleichs Zwischen der Bundesrepublik Deutschland und der Republik Korea - (한국과 서독간의 교통안전 비교)

  • 김홍상
    • Journal of Korean Society of Transportation
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    • v.5 no.2
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    • pp.55-72
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    • 1987
  • The work analyzes the existing situation and defines special problems concerning traffic accidents in the two countries. The report is divided into three parts: 1) Using the global approach of SMEED, the data were evaluated using multiple regression analysis, and homogeneous groups of countries were defined by cluster analysis. In the global approach, the linear model is better than SMEED's non-linear model in explaining the number of fatalities. Among the different groups of countries, the linear approach was found to be better suited for industrialized countries and the non-linear approach better for the developing countries. T도 comparison of traffic fatality data for the Federal Republic the developing countries. The comparison of traffic fatality data for the Federal Republic of Germany and the Republic of Korea showed different regression equations during the same time period. 2) The BOX/JENKINS time series analysis on a monthly basis points out clearly similar seasonal patterns for the two countries over the years studied. The decrease in traffic accidents following the intensification of the safety belt requirement was proved in the ARIMA model. It amounts to 7 to 8 percent fewer personal injury accidents and fatal accidents. The identified increase in safety in the Federal Republic of Germany since the 1970s is mainly due to the reduction of accident severity in residential areas. 3) Speeds and headways on motorways in th3e two countries were also compared. The measurements point out that German road users drive faster, take more risks, and accept shorter time gaps than Korean road users. However, the accident statistics show accident rates for Korea that are several times higher than those in the Federal Republic of Germany.

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Fluid Flow and Solute Transport in a Discrete Fracture Network Model with Nonlinear Hydromechanical Effect (비선형 hydromechanic 효과를 고려한 이산 균열망 모형에서의 유체흐름과 오염물질 이송에 관한 수치모의 실험)

  • Jeong, U-Chang
    • Journal of Korea Water Resources Association
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    • v.31 no.3
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    • pp.347-360
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    • 1998
  • Numerical simulations for fluid flow and solute transport in a fracture rock masses are performed by using a transient flow model, which is based on the three-dimensional stochastic and discrete fracture network model (DFN model) and is coupled hydraulic model with mechanical model. In the numerical simulations of the solute transport, we used to the particle following algorithm which is similar to an advective biased random walk. The purpose of this study is to predict the response of the tracer test between two deep bore holes (GPK1 and GPK2) implanted at Soultz sous Foret in France, in the context of the geothermal researches.l The data sets used are obtained from in situcirculating experiments during 1995. As the result of the transport simulation, the mean transit time for the non reactive particles is about 5 days between two bore holes.

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Die Organisation von Mikrostrukturen der zweisprachigen $W\"{o}rterb\"{u}cher$ Deutsch/Koreanisch (독-한 두말사전의 미시구조 조직)

  • Kim Kyong
    • Koreanishche Zeitschrift fur Deutsche Sprachwissenschaft
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    • v.5
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    • pp.183-202
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    • 2002
  • Die vorliegende Arbeit verfolgt zwei Ziele: zum einen sollen die Entwicklungen in der modernen zweisprachigen Lexikographie mit Ausgangssprache Deutsch skizzenhaft vorgestellt und einige Forschungsdefizite benannt werden, zum anderen sollen die Ergebnisse und Methoden der neueren Lexikographie anhand von Beispielartikeln der drei $einschl\"{a}gigen$ deutsch-koreanischen $Gro{\ss}w\"{o}rterblicher$ kontrastiert und diskutiert werden. Zuerst wird eine Typologie der zweisprachigen $W\"{o}rterb\"{u}cher$ erstellt, derzufolge es jeweils 2 aktive und 2 passive Worterblicher pro Sprachenpaar gibt. Das Aktiv-Passiv­Prinzip gilt als ein grundlegender Ausgangspunkt $f\"{u}r$ die zweisprachige Lexikographie. Eine Erweiterung der Unterscheidungskriterien scheint nicht $zweckm\"{a}{\ss}ig$ und angesichts praktischer Schwierigkeiten auch kaum realisierbar. $Pl\"{a}diert\;wird\;f\"{u}r\;eine\;st\"{a}rkere\;Ber\"{u}cksichtigung$ der Benutzungssituationen, zu denen z.B. der Grad der Sprachbeherr­schung der jeweiligen Benutzergruppe, die $m\"{o}glichen\;Benutzungsanl\"{a}sse$, der Kenntnisstand $bez\"{u}glich$ der Benutzerhinweise sowie die technische Geschicklichkeit bei der $W\"{o}rterbuch-benutzung\;etc.\;zu\;z\"{a}hlen$ sind. In makrostruktueller Hinsicht werden die Selektion und die Anordnung der Lemmata diskutiert. Bei der Lemmaauswahl $w\"{a}re\;es\;w\"{u}nschenswert$, auf der Grundlage eines Lemmavergleiches der verschiedensten Quellenworterbucher ein datenbasiertes Korpus zu erstellen. Dazu $k\"{o}nnten$ folgende Materialien ausgewertet werden: (1) einsprachige allgemeine (ad spezielle) $W\"{o}rterb\"{u}cher$ (z.B. Deutsch/Koreanisch), (2) zweisprachige allgemeine (od spezielle) Worterblicher (z.B. Deutsch-Koreanisch, Deutsch-Englisch) etc. Die $blo{\ss}e\;\"{U}bersetzung$ lediglich eines einzigen $Quellenw\"{o}rterbuches\;k\"{o}nnte$ dagegen zu $unerw\"{u}nschten\;Einseitigkeiten\;f\"{u}hren$. Was die Anordnung der Lemmata in zweisprachigen $W\"{o}rterb\"{u}chern$ betrifft, $k\"{o}nnen$ dieselben drei makrostrukturellen Typen unterschieden werden, wie in einsprachigen $W\"{o}rterb\"{u}chern$: (1) glattalphabetisch, (2) nischenalphabetisch, (3) nestalphabetisch. Unter den zu untersuchenden $W\"{o}rterb\"{u}chern$ weisen das EDK und das HDK die nischenalpha­betische Makrostruktur auf, das MDK ist dagegen nestalphabetisch angeordnet. Je nachdem, wie die Polysemiestruktur und die Mehr-Wort-Einheit kombinieren, werden die drei Arten der Mikrostruktur unterschieden: (1) die integrierte Mikrostruktur, (2) die nichtintegrierte Mikrostruktur, (3) die partiell integrierte Mikrostruktur. $W\"{a}hrend$ das EDK und das HDKeine integrierte Mikrostruktur besitzen, weist das HDK eine partiell integrierte Mikrostruktur auf. Die Artikelgestaltung durch die nichtintegrierte Mikrostruktur, die $h\"{a}ufig$ in der zweisprachigen Lexikographie angewandt wird und entsprechende Vorteile besitzt, sallte $k\"{u}nftig\;als\;Gestaltungsm\"{o}glichkeit\;st\"{a}rker$in Betracht gezogen werden. In Bezug auf die Organisation der Mikrostruktur werden vier Bauteile, das sind Lemma-, $\"{A}quivalent-$, Diskriminator- und Beispielangaben untersucht. Die $\"{U}bersetzungs\"{a}quivalente$ werden je nach dem lexikalisch-semantischen Abdeckungsgrad mit dem Lemma in drei Typen eingeteilt: (1) $Voll\"{a}quivalent,\;(2)\;Teil\"{a}quivalent,\;(3)\;Null\"{a}quivalent$. In der Mehrheit kommen die Teil- oder $Null\"{a}quivalente$ vor, weil die ausgangssprachlichen Lemmata und die zielsprachlichen $\"{A}quivalente$ in sich Polysemiestruktur aufweisen. $Informationsm\"{a}ngel$ auszugleichen ist die Funktion des Diskriminators, in dem Glosse, Markierungen und metasprachliche $Erl\"{a}uterungen$ zusammenwirken. $Verbesserungsw\"{u}rdig\;sind\;die\;g\"{a}ngigen$ deutsch-koreanischen $W\"{o}rterb\"{u}cher$ var allem im Hinblick auf die stilistischen Markierungen; die Inkongruenz des Stils zwischen den beiden verschiedenen Sprachen wird bislang zu wenig $ber\"{u}cksichtigt$ und sagar in ein und demselben $W\"{o}rterbuch$ nicht konsequent dargestellt. Trotz der relativen $Geringsch\"{a}tzung$ von Beispielangaben in der $europ\"{a}ischen$ zweisprachigen passiven Lexikographie sallte diesen in deutsch-koreanischen $W\"{o}rterb\"{u}chern$ mehr Aufmerksamkeit gewidrnet werden. Sie sind dem koreanischen Benutzer eine wichtige Hilfe, indem sie die $\"{A}quivalentenangaben\;implizite\;erg\"{a}nzen$ und Informationen $\"{u}ber$ die syntaktisch-semantische und pragmatische Kontextrestriktion bieten. $Dar\"{u}berhinaus$ stellen sie selbst interessante kulturelle, geistige und landeskundliche etc. Informationen dar. Was den Artikelaufbau betrifft, wird das Van Dale-Modell diskutiert, d.h. das kategoriell-semantisch-alphabetische Prinzip, das trotz mancher Kritikpunkte viele interessante Anregungen $f\"{u}r$ die zweisprachige Lexikographie Deutsch-Koreanisch bietet, wo z.B. noch nicht die $Pr\"{a}positionen$ in der Beispielangabe durch typographische Hervorhebung $pr\"{a}sentiert$ worden sind. Aus $Platzgr\"{u}nden$ sind hier nur wenige Beispielartikel mit substantivischen Lemmata $angef\"{u}hrt$ und analysiert worden. Um die $h\"{o}here$ Generalisierbarkeit zu erreichen, brauchen die Untersuchungs- materialien mindestens einen bestimmten Umfang. Derartige empirische Forschungen $k\"{o}nnen$ als Impulse dazu beitragen, $k\"{u}nftige\;W\"{o}rterb\"{u}cher$ im Sinne einer $Ber\"{u}cksichtigung$ neuerer lexikographischer Erkenntnisse verbessern zu helfen.

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Zum Verhältnis zwischen Sein und Wesen in der philosophische Anthropologie - In der ontologische Anthropologie bei Edith Stein - (철학적 인간학에서 존재와 본질의 문제 - 에디트 슈타인의 존재론적 인간학을 중심으로 -)

  • Lee, Eun-young
    • Journal of Korean Philosophical Society
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    • v.117
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    • pp.275-301
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    • 2011
  • Die Einzelwissenschaften, zum Beispiel, die Biologie, die Psychologie, Soziologie behandeln heuzutage den Menschen. Aber sie alle behandeln den Menschen nach ihren eigenen Gesichtpunkten. Infolgedessen $k{\ddot{o}}nnen$ die Einzelwissenschaften den ganzen Menschen als den Menschen nicht $ber{\ddot{u}}ksichtigen$. Jhre Anthropologien $m{\ddot{u}}{\ss}en$ daher weitgehend $beschr{\ddot{a}}nkt$ bleiben. Dagegen entwickelte Max Scheler im letzten Jahrhundert eine neue philosophische Anthropologie. Seine Anthropologie ist wirklich neu und grundgehend. Diese Anthropologie bestimmt den Menschen als Geist, Freiheit, Person. Aber Max Scheler betont allzusehr "den Geist" in seiner philosophischen Anthropologie und infolgedessen distanzierter sich vom "Leben" in seinem $Menschenverst{\ddot{a}}ndnis$. Die Verfasserin sieht hier in dieser philosophischen Anthropologie einen Dualismus zwischen den Geist und das leben. Und Verfasserin findet eine Integration von Geist und Leben in der ontologischen Anthropologie bei Edith Stein. Diese ontologische Anthropologie charakterisiert sich $folgenderma{\ss}en$. 1. Es ist eine Anthropologie des "$Ge{\ddot{o}}ffnet$-Seins." 2. Es ist eine Anthropologie des "$Gef{\ddot{u}}hlt$-Seins." 3. Es ist eine Anthropologie des "Einheits-Seins." Die Verfasserin behauptet infolgedessen die ontologische Anthropologie bei Edith Stein sei eine geeignete und $sachm{\ddot{a}}{\ss}ige$ Anthropologie.