• The Journal of the Korea Contents Association
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• v.9 no.5
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• pp.1-12
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• 2009

The correct detection of skin color is an important preliminary process in fields of face detection and human motion analysis. It is generally performed by three steps: transforming the pixel color to a non-RGB color space, dropping the illuminance component of skin color, and classifying the pixels by the skin color distribution model. Skin detection depends on by various factors such as color space, presence of the illumination, skin modeling method. In this paper we propose a 3d skin color model that can segment pixels with several ethnic skin color from images with various illumination condition and complicated backgrounds. This proposed skin color model are formed with each components(Y, Cb, Cr) which transform pixel color to YCbCr color space. In order to segment the skin color of several ethnic groups together, we first create the skin color model of each ethnic group, and then merge the skin color model using its skin color probability. Further, proposed model makes several steps of skin color areas that can help to classify proper skin color areas using small training data.

• Korean Journal of Pharmacognosy
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• v.49 no.3
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• pp.246-254
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• 2018

Pectin lyase-modified red ginseng extract (GS-E3D) is a newly developed ginsenoside Rd-enriched ginseng extract. This study was designed to investigate the skin safety of GS-E3D. Single oral toxicity, single dermal toxicity, bovine corneal opacity and permeability (BCOP) assay, skin irritation test with $SkinEthic^{TM}$ human epidermis model, skin sensitization local lymph node assay, and human patch test, were examined. The oral and dermal $LD_{50}$ value of GS-E3D was over 2,000 mg/kg in rats. GS-E3D was identified as a non-irritant to skin in BCOP assay, human epidermis models, and patch test from the 32 human subjects. The skin sensitization potential of GS-E3D was less than 25% in local lymph node assay. These results indicate that GS-E3D can be used as a safe ingredient without adverse effects in various skin care products.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.14 no.8
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• pp.1809-1818
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• 2010

In order to detect the skin color area from input images, many prior researches have divided an image into the pixels having a skin color and the other pixels. In a still image or videos, it is very difficult to exactly extract the skin pixels because lighting condition and makeup generate a various variations of skin color. In this thesis, we propose a method that improves its performance using hierarchical merging of 3D skin color model and context informations for the images having various difficulties. We first make 3D color histogram distributions using skin color pixels from many YCbCr color images and then divide the color space into 3 layers including skin color region(Skin), non-skin color region(Non-skin), skin color candidate region (Skinness). When we segment the skin color region from an image, skin color pixel and non-skin color pixels are determined to skin region and non-skin region respectively. If a pixel is belong to Skinness color region, the pixels are divided into skin region or non-skin region according to the context information of its neighbors. Our proposed method can help to efficiently segment the skin color regions from images having many distorted skin colors and similar skin colors.

• Toxicological Research
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• v.33 no.3
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• pp.191-203
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• 2017

Human eyes and skin are frequently exposed to chemicals accidentally or on purpose due to their external location. Therefore, chemicals are required to undergo the evaluation of the ocular and dermal irritancy for their safe handling and use before release into the market. Draize rabbit eye and skin irritation test developed in 1944, has been a gold standard test which was enlisted as OECD TG 404 and OECD TG 405 but it has been criticized with respect to animal welfare due to invasive and cruel procedure. To replace it, diverse alternatives have been developed: (i) For Draize eye irritation test, organotypic assay, in vitro cytotoxicity-based method, in chemico tests, in silico prediction model, and 3D reconstructed human cornealike epithelium (RhCE); (ii) For Draize skin irritation test, in vitro cytotoxicity-based cell model, and 3D reconstructed human epidermis models (RhE). Of these, RhCE and RhE models are getting spotlight as a promising alternative with a wide applicability domain covering cosmetics and personal care products. In this review, we overviewed the current alternatives to Draize test with a focus on 3D human epithelium models to provide an insight into advancing and widening their utility.

• Journal of the Korean Society of Safety
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• v.19 no.3 s.67
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• pp.95-100
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• 2004

H-pile can be more easily driven than pipe pile by pile driver and shows high skin friction and plugging effect. And lately It is well grown that the high strength H-pile has been widely used f3r pile foundations. To compare the skin frictions of H piles under different density soil conditions, this paper presents results of a series of model tests on vertically loaded group piles. Model piles made of steel embedded in weathered granite soil were used in this study. Pile arrangements $(2\times2,\;3\tunes3)$, pile space(2D, 4D, 6D), and soil density$(D_r=40\%,\;80\%)$ were tested. The main results obtained from the model tests can be summarized as follows. The series of tests found that compression load for group piles increases as number of piles increase and piles space ratic decrease to $D_r=40\%$ of soil density. The analysis also found that the theoretical value of skin friction for group piles is greater than practical value as piles space ratio increases to $D_r=40\%$ of soil density. Piles showed the greatest difference of the skin friction in case that the pile space ratio(S/D) is 6. The theoretical value by Meyerhof and DM-7 showed 1.83 times and 1.32 times respectively as great as practical value in case of S/D=6 and $2\times2$.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.40 no.4
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• pp.321-330
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• 2014

Ultraviolet B (UVB) is a primary environmental factor that induces adverse effects on skin such as photoaging, skin burn and cancer. UVB also increases the expression of $11{\beta}$-hydroxysteroid dehydrogenase type 1 ($11{\beta}-HSD1$), which converts inactive cortisone to active cortisol in response to a variety of stressors in target tissues. Thus, we have screened new herbal extracts that suppress $11{\beta}-HSD1$ expression induced by UVB in human dermal fibroblasts. We also investigated whether Trapa japonica (TJ) extract and its fractions inhibit UVB-induced photoaging in Hs68 cells and 3D skin model. Results showed that TJ extract inhibited the increase of $11{\beta}-HSD1$ expression in UVB-exposed Hs68 cells significantly. TJ extract and its fractions not only inhibited $11{\beta}-HSD1$ expression, but also suppressed the increase of matrix metalloproteinases (MMP-1, 3, 9) and proinflammatory cytokines (IL-6, 8) in UVB-irritated Hs68 cells. TJ extract also inhibited MMP-1 expression in UVB-irritated 3D skin model. In addition, TJ extract recovered UVB-induced decreases of epidermal thickness and PCNA-positive cells in 3D skin model. Taken together, these results suggest that TJ extract and its fractions inhibit UVB-induced skin photoaging by interfering with $11{\beta}-HSD1$ and MMPs.

• Journal of the Korean Society of Safety
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• v.20 no.3 s.71
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• pp.152-157
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• 2005

This experimental study was devoted to investigate skin friction of H group piles with uplift loading conditions in granite soil under laboratory test. Model piles made of steel embedded in weathered granite soil were used in this study. Pile arrangements($2{\times}2,\;3{\times}3$), pile space(2D, 4D, 6D), and soil density($D_r=40%,\;80%$) were tested. The main results obtained from the model tests can be summarized as follows. The series of tests found that ultimate uplift load and displacement for group piles were increased as piles space ratio increases to $D_r=40%$ of soil density. In the relative density of $D_r=80%$, bearing capacity for group piles was greater than for single pile. In the relative density of $D_r=40%$, the theoretical value of skin friction for group piles was greater than practical value. In the relative density of $D_r=80%$, both theoretical and practical value of skin friction for group piles were increased as piles space ratio increases.

• Journal of Korea Multimedia Society
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• v.12 no.5
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• pp.737-744
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• 2009

This paper is to study and implement 3D Virtual Face Aesthetic Surgery System which provides more satisfaction by comparing the before-and-after plastic face surgery using 3D face model. For this study, we implemented 3D Face Model Generating System which resembles 2D image of the user based on 3D Korean standard face model and user's 2D pictures. The proposed 3D Virtual Face Aesthetic Surgery System in this paper consists of 3D Face Model Generating System, 3D Skin Texture Mapping System, and Detailed Adjustment System for reflecting the detailed description of face. The proposed system provides more satisfaction to the medical uses and stability in the surgery in compare with other existing systems.

• Journal of Internet Computing and Services
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• v.7 no.2
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• pp.23-35
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• 2006

This work presents o novel method which extract facial region und features from motion picture automatically and controls the 3D facial expression in real time. To txtract facial region and facial feature points from each color frame of motion pictures a new nonparametric skin color model is proposed rather than using parametric skin color model. Conventionally used parametric skin color models, which presents facial distribution as gaussian-type, have lack of robustness for varying lighting conditions. Thus it needs additional work to extract exact facial region from face images. To resolve the limitation of current skin color model, we exploit the Hue-Tint chrominance components and represent the skin chrominance distribution as a linear function, which can reduce error for detecting facial region. Moreover, the minimal facial feature positions detected by the proposed skin model are adjusted by using edge information of the detected facial region along with the proportions of the face. To produce the realistic facial expression, we adopt Water's linear muscle model and apply the extended version of Water's muscles to variation of the facial features of the 3D face. The experiments show that the proposed approach efficiently detects facial feature points and naturally controls the facial expression of the 3D face model.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.42 no.4
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• pp.343-349
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• 2016

Many minerals and nutrient salts are abundant in Jeju lava sea water. The objective of this study was to evaluate the skin hydration effects of Jeju lava sea water. The skin barrier serves as a protective barrier that prevents the loss of moisture. The water holding capacity and water transport of the epidermis have been proposed to be important determinants of skin hydration. Jeju lava sea water increased the mRNA expression of filaggrin and caspase-14 which is related to natural moisturizing factor (NMF) formation. Aquaporins 3 (AQP3) are proteins that facilitate the transport of water across cell membranes. Jeju lava sea water increased the mRNA expression and protein expression of AQP3. We employed a skin equivalent model to assess the efficacy of Jeju lava sea water. In a skin equivalent model, Jeju lava sea water increased the CD44 (hyaluronic acid receptor) which is related to skin hydration. From these results, we found out Jeju lava sea water maybe help to skin hydration.