• 한국기계가공학회지
• /
• 제18권3호
• /
• pp.33-40
• /
• 2019

FDM 3D printers have become widespread, and investment in the 3D printer industry is increasing. Therefore, many 3D printers are released and the functions of products are emphasized. However, to lower unit prices, open-type 3D printers are sold in kit form, and their performance is very low. If the 3D printer has many heat sources and is sealed, there is the possibility that the main accessories (the main board, power supply, and motor) will be damaged by trapped heat. At the same time, if the ambient temperature is low due to the properties of the material, the output quality deteriorates. In this study, we analyzed the temperature rise of the main accessories and the quality of the output by the heat bed when a chamber was added to an open-type 3D printer. We also compared the quality of the output due to the air flow with the temperature rise of the main accessories. Moreover, we found the optimal value. As a result of the quality analysis, it was finally confirmed that the case with the chamber at $95^{\circ}C$ was the best for the printing condition. In addition, in the absence of the chamber, the bending of the specimen was found to be large, and in the case of the chamber, the degree of bending was slightly decreased by 0.05 mm.

• 한국컴퓨터그래픽스학회논문지
• /
• 제24권3호
• /
• pp.61-71
• /
• 2018

RGB-D 카메라 촬영 영상에 대한 카메라 포즈 추정을 통하여 복원한 3차원 전역 공간의 점 집합으로부터 삼각형 메쉬를 생성할 때, 일반적으로 메쉬의 크기가 커질수록 3차원 모델의 품질 또한 향상된다. 하지만 어떤 한계를 넘어서 삼각형 메쉬의 해상도를 높일 경우, 메모리 요구량의 과도한 증가나 실시간 렌더링 성능저하 문제뿐만 아니라 RGB-D 센서의 정밀도 한계로 인한 접 집합 데이터의 노이즈에 민감해지는 문제가 발생한다. 본 논문에서는 실시간 응용에 적합한 3차원 모델 생성을 위하여 비교적 적은 크기의 삼각형 메쉬에 대하여 3차원 점 집합의 촬영 색상으로부터 고화질의 텍스쳐를 생성하는 기법을 제안한다. 특히 카메라 포즈 추정을 통하여 생성한 3차원 점 집합 공간과 2차원 텍스쳐 공간 간의 매핑 관계를 활용한 간단한 방법을 통하여 RGB-D 카메라 촬영 영상으로부터 복원한 3차원 모델에 대하여 효과적으로 텍스쳐를 생성할 수 있음을 보인다.

• 핵의학기술
• /
• 제24권1호
• /
• pp.33-38
• /
• 2020

비타민D는 체내에서 칼슘 대사를 조절하여 뼈의 건강을 유지하며, 세포의 증식 및 분화의 조절, 면역 기능 등에 관여하는 중요한 역할을 한다. 부족 시 구루병, 골다공증의 위험이 높아지고 심혈관계 질환, 당뇨병, 일부 암 등의 발병 위험이 증가하는 것으로 보고되고 있다. 특히 한국은 비타민D 부족의 인구 비율이 매우 높은 국가 중 하나이다. 따라서 비타민D 부족의 진단 및 치료를 위해 혈중 25-OH-VitD 또는 25-OH-VitD3의 정확한 측정이 요구된다. 이에 본원에서 시행하고 있는 25-OH-VitD와 25-OH-VitD3검사를 비교 평가하여 비타민D에 대한 정확한 진단 및 치료에 기여하고자 한다. 25-OH-VitD와 25-OH-VitD3의 결과를 전향적으로 측정하여 상관성, 재현성, 모집단 분포율을 구하였다. 또한 2017년 4월에서 2019년 6월까지 서울아산병원 핵의학과 혈액검사실에서 측정한 내부정도관리와 대한핵의학기술학회에서 주관하는 2018년 상반기, 하반기 외부정도관리(기관간 숙련도 평가)에 참여한 결과를 비교하였다. 그 결과 97개의 검체를 대상으로 25-OH-VitD는 25-OH-VitD3 × 0.9 + 0.3 (R >0.9)로 강력한 양의 상관관계를 보였다. 반복 측정을 통한 재현성 평가 결과 평균 diff(%) 값은 7.7%, 7.4%로 모두 우수한 성적을 나타내었다. 또한 모집단 분포를 비교한 결과 통계적으로 유의한 차이를 보이지 않았다(p>0.05). 2017년 4월에서 2019년 6월까지 서울아산병원 핵의학 혈액검사실에서 측정한 내부정도관리 결과값은 평균(CV%) 6.2%, 6.8%을 나타내었다. 2018년 상반기 외부정도관리(기관간 숙련도 평가) 수행도 평가 결과 Z 값이 25-OH-VitD는 저, 중, 고농도에 대해 -1.10, -1.00, -0.90이며 25-OH-VitD3는 0.22, 0.47, 1.10이고 하반기 수행도 평가 결과는 각각 -0.80, -0.30, -0.10과 -0.01, 1.50, 1.30으로 모두 Z ≤ 2.0의 적합한 결과를 얻었다. 방사면역 측정법에 의한 25-OH-VitD와 25-OH-VitD3 검사의 비교 평가 결과 상관성, 재현성, 모집단 분포율, 내부정도관리, 외부정도관리(기관간 숙련도 평가) 모두 우수한 성적을 보였다. 따라서 혈액 내 25-OH-VitD 또는 25-OH-VitD3로 단독 측정이 가능한 방사면역 측정법은 비타민D 부족에 대한 스크리닝 검사로 적합한 것으로 사료된다.

• 정보처리학회논문지:소프트웨어 및 데이터공학
• /
• 제5권4호
• /
• pp.195-202
• /
• 2016

안경식 3차원 입체영상 콘텐츠에 대한 사용자 평가는 객관적/주관적 평가 방법을 활용하여 많은 연구가 이루어지고 있지만 무안경식 3차원 입체 영상 콘텐츠에 대한 사용자 평가는 미비한 실정이며 특히 생체신호를 적용한 객관적 평가에 대한 연구는 거의 이루어지지 않고 있다. 이에 본 연구에서는 무안경 입체 영상 화질에 대한 객관적 사용자 평가 도구개발을 위한 사전연구로서 무안경 입체영상 화질 변화에 따른 뇌파(Electroencephalogram, EEG)의 변화를 분석하였다. 이를 위하여 무안경식 입체영상 시스템의 디스플레이로 활용되고 있는 렌티큘러 방식 입체 영상을 최적입체영상과 왜곡입체영상으로 구분하여 제작하고, 이를 총 26명의 피험자에게 차례로 제시하며 8개 채널의 뇌파를 측정하였다. 각 영상 시청시 획득한 뇌파를 채널별과 주파수별로 분류하여 통계적 상관관계를 분석하였다. 분석 결과 뇌파진동 중 알파파의 경우 최적입체영상과 왜곡입체영상 사이에서 통계적으로 유의미한 차이가 확인되지 않았으나 베타파의 경우 통계적으로 유의미한 차이가 확인되었다. 베타파의 경우 왜곡입체영상에서 최적입체영상보다 통계적으로 유의미하게 높게 나타났으며 이는 왜곡입체영상 시청 시 피로감 또는 불안감 증폭에 따른 베타파의 뇌파활동이 높아진 것으로 해석된다. 본 연구결과를 바탕으로 뇌파분석 기법이 렌티큘러 방식의 무안경 입체영상 화질 평가를 위한 객관적 평가 수단으로 활용될 수 있는 가능성을 확인하였다.

• 한국멀티미디어학회논문지
• /
• 제22권1호
• /
• pp.55-61
• /
• 2019

Almost all 3D displays have a brightness reduction in the 3D mode comparing to the 2D mode. When the brightness is reduced, one of the color attributes, the colorfulness, is decreased. In this case, the viewer feels that the image quality is deteriorated. In this paper, we proposed a method to compensate for the degradation of colorfulness due to brightness reduction in 3D mode for high quality 3D image viewing using the CIECAM02 model and the color correction matrix. As a result of applying the proposed method, we can confirm that the colorfulness is improved in 3D mode.

• Korean Journal of Radiology
• /
• 제23권2호
• /
• pp.256-263
• /
• 2022

Objective: This study aimed to evaluate the image quality and dose reduction of low-dose three-dimensional (3D) rotational angiography (RA) for evaluating intracranial aneurysms. Materials and Methods: We retrospectively evaluated the clinical data and 3D RA datasets obtained from 146 prospectively registered patients (male:female, 46:100; median age, 58 years; range, 19-81 years). The subjective image quality of 79 examinations obtained from a conventional method and 67 examinations obtained from a low-dose (5-seconds and 0.10-μGy/frame) method was assessed by two neurointerventionists using a 3-point scale for four evaluation criteria. The total image quality score was then obtained as the average of the four scores. The image quality scores were compared between the two methods using a noninferiority statistical testing, with a margin of -0.2 (i.e., score of low-dose group - score of conventional group). For the evaluation of dose reduction, dose-area product (DAP) and air kerma (AK) were analyzed and compared between the two groups. Results: The mean total image quality score ± standard deviation of the 3D RA was 2.97 ± 0.17 by reader 1 and 2.95 ± 0.20 by reader 2 for conventional group and 2.92 ± 0.30 and 2.95 ± 0.22, respectively, for low-dose group. The image quality of the 3D RA in the low-dose group was not inferior to that of the conventional group according to the total image quality score as well as individual scores for the four criteria in both readers. The mean DAP and AK per rotation were 5.87 Gy-cm² and 0.56 Gy, respectively, in the conventional group, and 1.32 Gy-cm² (p < 0.001) and 0.17 Gy (p < 0.001), respectively, in the low-dose group. Conclusion: Low-dose 3D RA was not inferior in image quality and reduced the radiation dose by 70%-77% compared to the conventional 3D RA in evaluating intracranial aneurysms.

• 품질경영학회지
• /
• 제50권3호
• /
• pp.373-386
• /
• 2022

Purpose: This study proposes the application of Six Sigma management innovation method for more systematically enhanced execution of Quality by Design (QbD) activities. QbD requires a deeper understanding of the product and process at the design and development stage of the drug, and it is very important to ensure that no fault is fundamentally generated through thorough process control. Methods: Analyzing the background and specific procedures of quality improvement based on the drug design basis, and analyzing the key contents of each step, we have differentated and common points from the 6 Sigma methodology. We propose a new model of Six Sigma management innovation method suitable for pharmaceutical industry. Results: Regulatory agencies are demanding results from statistical analysis as a scientific basis in developing medicines to treat human life through quality improvement activities based on drug design. By utilizing the education system to improve the statistical analysis capacity in the Six Sigma activities and operating the 6 Sigma Belt system in conjunction, it helped systematically strengthen the execution power of quality improvement activities based on pharmaceutical design based on the members of the pharmaceutical industry. Conclusion: By using QbD Six Sigma, which combines quality enhancement based on pharmaceutical design basis and Six Sigma methodology suitable for pharmaceutical industry, it is possible to obtain satisfactory results both by pharmaceutical companies and regulators by using appropriate statistical analysis methods for preparing scientific evidence data required by regulatory.

• 핵의학기술
• /
• 제28권1호
• /
• pp.35-40
• /
• 2024

Purpose: To improve the image quality in positron emission tomography (PET), the attenuation correction technique based on the computed tomography (CT) data is important process. However, the artifact is caused by metal material during PET/CT scan, and the image quality is degraded. Therefore, the purpose of this study was to evaluate image quality according to with and without iterative metal artifact reduction (iMAR) algorithm using customized 3D printing phantom. Materials and Methods: The Hoffman and Derenzo phantoms were designed. To protect the gamma ray transmission and express the metal portion, lead substance was located to the surface. The SiPM based PET/CT was used for acquisition of PET images according to application with and without iMAR algorithm. The quantitative methods were used by signal to noise ratio (SNR), coefficient of variation (COV), and contrast to noise ratio (CNR). Results and Discussion: The results shows that the image quality applying iMAR algorithm was higher 1.15, 1.19, and 1.11 times than image quality without iMAR algorithm for SNR, COV, and CNR. Conclusion: In conclusion, the iMAR algorithm was useful for improvement of image quality by reducing the metal artifact lesion.

• Journal of information and communication convergence engineering
• /
• 제19권2호
• /
• pp.102-107
• /
• 2021

In this paper, we propose a new three-dimensional (3D) photon-counting integral imaging reconstruction method using a merging reconstruction process and maximum likelihood estimation (MLE). The conventional 3D photon-counting reconstruction method extracts photons from elemental images using a Poisson random process and estimates the scene using statistical methods such as MLE. However, it can reduce the photon levels because of an average overlapping calculation. Thus, it may not visualize 3D objects in severely low light environments. In addition, it may not generate high-quality reconstructed 3D images when the number of elemental images is insufficient. To solve these problems, we propose a new 3D photon-counting merging reconstruction method using MLE. It can visualize 3D objects without photon-level loss through a proposed overlapping calculation during the reconstruction process. We confirmed the image quality of our proposed method by performing optical experiments.

• International Journal of Quality Innovation
• /
• 제3권2호
• /
• pp.29-37
• /
• 2002

This paper presents a framework for processing a structured approach of R&D investment. It presents nine steps to operate R&D investment from analysis of environment situation to review and feedback its activity. Also fundamental questions fur effective R&D management in business are discussed and after that critical eight success factors for R&D investment are discussed.