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박달나무로부터 분리된 페놀성 화합물의 항산화 및 Tyrosinase 저해 활성 연구 (Identification of Anti-Oxidant and Anti-Tyrosinase Activity of Phenolic Components Isolated from Betula schmidtii)

  • 왕다혜;정하숙
    • 한국식품영양학회지
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    • 제34권5호
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    • pp.553-559
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    • 2021
  • The aim of study to investigate the phytochemicals and biological activities the bark of Betula schmidtii. The studies consisted of the solvent extraction, followed by the isolation of phenolic components 1~3 from ethyl acetate-soluble fraction of Betula schmidtii Bark. Their chemical structures were identified as arbutin (1), ρ-coumaric acid (2) and ferulic acid (3) using Ultraviolet-Visible (UV-Vis) Spectrophotometer, Electrospray Ionization Mass Spectrometry (ESI-MS) (negative ion mode), 1H-Nuclear Magnetic Resonance (NMR), 13C-NMR, 1H-1H Correlation Spectroscopy (COSY) and 1H-13C Hetero Nuclear Multiple Quantum Correlation (HMQC) spectral data. Compounds 1~3 shows the anti-oxidant effect with IC50 values of 29.74±1.52, 21.32±1.07 and 34.41±1.24 in 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity, respectively. Also, compounds 1~3 exhibited mushroom tyrosinase inhibitory activity with IC50 values of 31.14±1.07, 42.54±1.46 and 69.22±1.43 µM, respectively.

SHERPA기법을 이용한 항공기 착륙상황에서 발생 가능한 인적오류 예측 (Predicting Human Errors in Landing Situations of Aircraft by Using SHERPA)

  • 최재림;한혁재;함동한
    • 한국항공운항학회지
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    • 제29권2호
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    • pp.14-24
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    • 2021
  • This study aims to examine probable human errors when landing an airplane by the use of SHERPA(systematic human error reduction and prediction approach) and propose methods for preventing the predictive human errors. It has been reported that human errors are concerned with a lot of accidents or incidents of an airplane. It is significant to predict presumable human errors, particularly in the operation mode of human-automation interaction, and attempt to reduce the likelihood of predicted human error. By referring to task procedures and interviewing domain experts, we analyzed airplane landing task by using HTA(hierarchical task analysis) method. In total, 6 sub-tasks and 19 operations were identified from the task analysis. SHERPA method was used for predicting probable human error types for each task. As a result, we identified 31 human errors and predicted their occurrence probability and criticality. Based on them, we suggested a set of methods for minimizing the probability of the predicted human errors. From this study, it can be said that SHERPA can be effectively used for predicting probable human error types in the context of human-automation interaction needed for navigating an airplane.

Crystal Structure and Molecular Mechanism of Phosphotransbutyrylase from Clostridium acetobutylicum

  • Kim, Sangwoo;Kim, Kyung-Jin
    • Journal of Microbiology and Biotechnology
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    • 제31권10호
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    • pp.1393-1400
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    • 2021
  • Acetone-butanol-ethanol (ABE) fermentation by the anaerobic bacterium Clostridium acetobutylicum has been considered a promising process of industrial biofuel production. Phosphotransbutyrylase (phosphate butyryltransferase, PTB) plays a crucial role in butyrate metabolism by catalyzing the reversible conversion of butyryl-CoA into butyryl phosphate. Here, we report the crystal structure of PTB from the Clostridial host for ABE fermentation, C. acetobutylicum, (CaPTB) at a 2.9 Å resolution. The overall structure of the CaPTB monomer is quite similar to those of other acyltransferases, with some regional structural differences. The monomeric structure of CaPTB consists of two distinct domains, the N- and C-terminal domains. The active site cleft was formed at the interface between the two domains. Interestingly, the crystal structure of CaPTB contained eight molecules per asymmetric unit, forming an octamer, and the size-exclusion chromatography experiment also suggested that the enzyme exists as an octamer in solution. The structural analysis of CaPTB identifies the substrate binding mode of the enzyme and comparisons with other acyltransferase structures lead us to speculate that the enzyme undergoes a conformational change upon binding of its substrate.

Estimation of Phosphorus Concentration in Silicon Thin Film on Glass Using ToF-SIMS

  • Hossion, M. Abul;Murukesan, Karthick;Arora, Brij M.
    • Mass Spectrometry Letters
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    • 제12권2호
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    • pp.47-52
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    • 2021
  • Evaluating the impurity concentrations in semiconductor thin films using time of flight secondary ion mass spectrometry (ToF-SIMS) is an effective technique. The mass interference between isotopes and matrix element in data interpretation makes the process complex. In this study, we have investigated the doping concentration of phosphorus in, phosphorus doped silicon thin film on glass using ToF-SIMS in the dynamic mode of operation. To overcome the mass interference between phosphorus and silicon isotopes, the quantitative analysis of counts to concentration conversion was done following two routes, standard relative sensitivity factor (RSF) and SIMetric software estimation. Phosphorus doped silicon thin film of 180 nm was grown on glass substrate using hot wire chemical vapor deposition technique for possible applications in optoelectronic devices. Using ToF-SIMS, the phosphorus-31 isotopes were detected in the range of 101~104 counts. The silicon isotopes matrix element was measured from p-type silicon wafer from a separate measurement to avoid mass interference. For the both procedures, the phosphorus concentration versus depth profiles were plotted which agree with a percent difference of about 3% at 100 nm depth. The concentration of phosphorus in silicon was determined in the range of 1019~1021 atoms/cm3. The technique will be useful for estimating distributions of various dopants in the silicon thin film grown on glass using ToF-SIMS overcoming the mass interference between isotopes.

Corrosion Inhibition Studies on Low Carbon Steel in Hydrochloric Acid Medium Using o-Vanillin-Glutamine Schiff Base

  • Thusnavis, G. Rexin;Archana, T.V.;Palanisamy, P.
    • Corrosion Science and Technology
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    • 제21권1호
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    • pp.32-40
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    • 2022
  • The o-Vanillin - Glutamine Schiff base [2-Hydroxy-3-Methoxy BenzylidineCarbomyl) -2-Butanoic Acid] was examined for low carbon steel corrosion inhibition in acid media. Weight loss studies were carried out at three different temperatures to determine the inhibition efficiency (IE). Electrochemical impedance spectroscopy revealed that the charge transfer resistance controlled the corrosion reaction and Tafel polarization indicated that the Schiff base acts as mixed mode of inhibitor. SEM images were recorded for the surface morphology of the low carbon steel surface. DFT studies revealed corrosion control mechanisms using quantum chemical parameters such as EHOMO, ELUMO, energy gap (∆E), chemical Hardness (η), chemical Softness (σ), Electronegativity (χ), and the fraction of electron transferred (∆N), which is calculated using Gaussian software 09. The gas-phase geometry was fully optimized in the Density Functional Theory (DFT/B3LYP-6-31G (d)).The DFT results are in good agreement with the experimental results. All the results proved that the Schiff Base (2-Hydroxy-3-Metoxy BenzylidineCarbomyl) -2-Butanoic is a suitable alternative for corrosion inhibition of low carbon steel in acid media.

윤리적 소비와 소비가치의 관계에 대한 소비자 인식 변화: 소셜 빅데이터를 활용한 윤리적 소비와 소비가치의 키워드 변화 분석을 중심으로 (A Study on the Changes in Consumer Perceptions of the Relationship between Ethical Consumption and Consumption Value: Focusing on Analyzing Ethical Consumption and Consumption Value Keyword Changes Using Big Data)

  • 신은정;고애란
    • Human Ecology Research
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    • 제59권2호
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    • pp.245-259
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    • 2021
  • The purpose of this study was to analyze big data to identify the sub-dimensions of ethical consumption, as well as the consumption value associated with ethical consumption that changes over time. For this study, data were collected from Naver and Daum using the keyword 'ethical consumption' and frequency and matrix data were extracted through Textom, for the period January 1, 2016, to December 31, 2018. In addition, a two-way mode network analysis was conducted using the UCINET 6.0 program and visualized using the NetDraw function. The results of text mining show increasing keyword frequency year-on-year, indicating that interest in ethical consumption has grown. The sub-dimensions derived for 2014 and 2015 are fair trade, ethical consumption, eco-friendly products, and cooperatives and for 2016 are fair trade, ethical consumption, eco-friendly products and animal welfare. The results of deriving consumption value keywords were classified as emotional value, social value, functional value and conditional value. The influence of functional value was found to be growing over time. Through network analysis, the relationship between the sub-dimensions of ethical consumption and consumption values derived each year from 2014 to 2018 showed a significantly strong correlation between eco-friendly product consumption and emotional value, social value, functional value and conditional value.

Hysteretic performance of a novel composite wall panel consisted of a light-steel frame and aerated concrete blocks

  • Wang, Xiaoping;Li, Fan;Wan, Liangdong;Li, Tao
    • Steel and Composite Structures
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    • 제41권6호
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    • pp.861-871
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    • 2021
  • This study aims at investigating the hysteretic performance of a novel composite wall panel fabricated by infilling aerated concrete blocks into a novel light-steel frame used for low-rise residential buildings. The novel light-steel frame is consisted of two thin-wall rectangular hollow section columns and a truss-beam assembled using patented U-shape connectors. Two bare light-steel frames and two composite wall panels have been tested to failure under horizontal cyclic loading. Hysteretic curves, lateral resistance and stiffness of four specimens have been investigated and analyzed. Based on the testing results, it is found that the masonry infill can significantly increase the lateral resistance and stiffness of the novel light-steel frame, about 2.3~3 and 21.2~31.5 times, respectively. Failure mode of the light-steel frame is local yielding of the column. For the composite wall panel, firstly, masonry infill is crushed, subsequently, local yielding may occur at the column if loading continues. Hysteretic curve of the composite wall panel obtained is not plump, implying a poor energy dissipation capacity. However, the light-steel frame of the composite wall panel can dissipate more energy after the masonry infill is crushed. Therefore, the composite wall panel has a much higher energy dissipation capacity compared to the bare light-steel frame.

Numerical Analysis for Hydrodynamic Performance of OWC Devices with Multiple Chambers in Waves

  • Kim, Jeong-Seok;Nam, Bo Woo
    • 한국해양공학회지
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    • 제36권1호
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    • pp.21-31
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    • 2022
  • In recent years, various studies have been conducted on oscillating-water-column-type wave energy converters (OWC-WECs) with multiple chambers with the objective of efficiently utilizing the limited space of offshore/onshore structures. In this study, a numerical investigation based on a numerical wave tank was conducted on single, dual, and triple OWC chambers to examine the hydrodynamic performances and the energy conversion characteristics of the multiple water columns. The boundary value problem with the Laplace equation was solved by using a numerical wave tank based on a finite element method. The validity of the current numerical method was confirmed by comparing it with the measured data in the previous experimental research. We undertook a series of numerical simulations and observed that the water column motion of sloshing mode in a single chamber can be changed into the piston motion of different phases in multiple OWC chambers. Therefore, the piston motion in the multiple chambers can generate considerable airflow at a specific resonant frequency. In addition, the division of the OWC chamber results in a reduction of the time-dependent variability of the final output power from the device. As a result, the application of the multiple chambers leads to an increase of the energy conversion performance as well as a decrease of the variability of the wave energy converter.

Experimental and numerical study of a steel plate-based damper for improving the behavior of concentrically braced frames

  • Denise-Penelope N. Kontoni;Ali Ghamari;Chanachai Thongchom
    • Steel and Composite Structures
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    • 제47권2호
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    • pp.185-201
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    • 2023
  • Despite the high lateral stiffness and strength of the Concentrically Braced Frame (CBF), due to the buckling of its diagonal members, it is not a suitable system in high seismic regions. Among the offered methods to overcome the shortcoming, utilizing a metallic damper is considered as an appropriate idea to enhance the behavior of Concentrically Braced Frames (CBFs). Therefore, in this paper, an innovative steel damper is proposed, which is investigated experimentally and numerically. Moreover, a parametrical study was carried out to evaluate the effect of the mechanism (shear, shear-flexural, and flexural) considering buckling mode (elastic, inelastic, and plastic) on the behavior of the damper. Besides, the necessary formulas based on the parametrical study were presented to predict the behavior of the damper that they showed good agreement with finite element (FE) results. Both experimental and numerical results confirmed that dampers with the shear mechanism in all buckling modes have a better performance than other dampers. Accordingly, the FE results indicated that the shear damper has greater ultimate strength than the flexural damper by 32%, 31%, and 56%, respectively, for plates with elastic, inelastic, and plastic buckling modes. Also, the shear damper has a greater stiffness than the flexural damper by 43%, 26%, and 53%, respectively, for dampers with elastic, inelastic, and plastic buckling modes.

Influence of basalt fibres on the flexural performance of hypo sludge reinforced concrete beams with SBR latex

  • S. Srividhya;R. Vidjeapriya
    • Structural Engineering and Mechanics
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    • 제87권6호
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    • pp.615-624
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    • 2023
  • The focus of this study is on the structural behaviour of reinforced concrete beams in which basalt fiber and SBR latex were added and the cement was partially replaced with 10% of hypo sludge. Eight different mixes of reinforced beam specimens were tested under static loading behaviour. The experiments showed, the structural behaviour with features such as load-deflection relationships, crack pattern, crack propagation, number of crack, crack spacing and moment curvature. A stress-strain relationship to represent the overall behavior of reinforced concrete in tension, which includes the combined effects of cracking and mode of failure along the reinforcement, is proposed. The structural behaviour results of reinforced concrete beams with various types of mix were tested at the age of 28 days. The investigation revealed that the flexural behaviors of hypo sludge reinforced concrete beams with addition of basalt fiber and SBR latex was higher than that of control concrete reinforced beam. The specimen (LHSBFC) with 10% hypo sludge, 0.25% Basalt fiber and 10% SBR latex showed an increase of 5.08% load carrying capacity, 7.6% stiffness, 3.97% ductility, 31.29% energy dissipation when compared to the control concrete beam. The analytical investigation using FEM shows that it was in good agreement with the experimental investigation.