• Proceedings of the Safety Management and Science Conference
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• 2006.11a
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• pp.437-450
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• 2006

The Contour Crafting(CC) process, which has been developed at the University of Southern California, aims at automated construction of whole houses as well as sub-components. For this purpose, new trowel mechanism is basically needed in order to fabricate the true 3D shape. This paper presents our concepts and initial investigation of 3D free form fabrication using the pivoting side trowel. Specifically, the status of research and development of the processand experiments with ceramics materials, and its potential application areas are detailed.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.25 no.12
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• pp.1236-1242
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• 2014

In this work, a D-band VCO(Voltage Controlled Oscillator) has been developed in a 65-nm CMOS technology. The circuit was designed based on push-push mechanism. The output oscillation frequency of the fabricated VCO varied from 152.7 GHz to 165.8 GHz, and the measured output power was from -17.3 dBm to -8.7 dBm. A phase noise of -90.9 dBc/Hz is achieved at 10 MHz offset. The chip size of the circuit is $470{\mu}m{\times}360{\mu}m$ including the probing pads.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.26 no.6
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• pp.1361-1373
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• 2016

Recently the need for user authentication with increasing, there are a variety of mechanisms, such as password, graphic authentication, token, biometrics and multiple authentication. in particular, the data of the 2-dimensional(2D) factors such as password, graphic authentication, biometrics is used because of the convenience. The stored information is problematic in that additional data recording needs to be performed whenever authentication data is updated. Furthermore, this storage method is problematic in that the time it takes to perform authentication increases because the time it takes to compare storage data with authentication data increases in proportion to an increase in the amount of the storage data. Accordingly, authentication through the rapid comparison of storage data with authentication data is a very important factor in data recording and authentication technology using memory. Using the three-dimensional(3D) optical memory by variously changing the recoding elements during recoding of data constitutes the way that multiple recoding different data storage. This enables high-density recoding in this way, and by applying the possible parallel processing at the time of recording and restoring method, provided that it is possible to quickly record and restore the data. In addition, each time to solve problems that require additional data recorded by a combination of the stored data record in the old data using a combination of the authentication. The proposed mechanism is proposed an authentication method using scheme after the recoding data in 3D optical memory to apply the conditions corresponding to the recoding condition when restoring the recorded data and through the experiment it was confirmed possible application as an authentication mechanism.

• Transactions of the Korean Society of Mechanical Engineers
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• v.19 no.1
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• pp.22-37
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• 1995

Industrial robot has played a central role in the production automation such as welding, assembling, and painting. There has been, however, little effort to the application of robots in machining work(grinding, cutting, milling, etc.) which is typical 3D work. The machining automation requires a high stiffness robot arm to reduce deformation and vibration. Conventional articulated robots have serially connecting links from the base to the gripper. So, they have very weak structure for he machining work. Stewart Platform is a typical parallel robotic mechanism with a very high stiffness but it has a small work space and a large installation space. This research proposes a new machining robot arm with a double parallel mechanism. It is composed of two platforms and a central axis. The central axis will connect the motions between the first and the second platforms. Therefore, the robot has a large range of work space as well as a high stiffness. This paper will introduce the machining work using the robot and design the proposed robot arm.

• Microbiology and Biotechnology Letters
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• v.9 no.4
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• pp.179-183
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• 1981

An extracellular chitinase was purified from the culture fluid of Streptomyces sp. 115-5, and its inhibition mechanism by end product was studied. The activity of chitinase was suppressed by the reducing sugar as the reaction proceeded, and the activity was inhibited by the addition of D-glucose. Besides D-glucose, the rate of chitin hydrolysis was inhibited by D-glucuronic acid, D-sorbitol and D-xylose in the reaction system of the enzyme. it was found that the hydroxyl groups at the C-2, C-3 and C-4 position of D-glucose molecule play an important role in the inhibition of the chitinase activity. D-glucose was found to inhibit the enzyme activity by mixed type of competitive and non-competitive mode.

• Proceedings of the SCSK Conference
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• 2003.09b
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• pp.174-183
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• 2003

To obtain effective and safe topical depigmenting agents, we synthesized hydroxybenzoates, alkoxybenzoates, and 3,4,5-trimethoxycinnamate containing a thymol moiety and screened then for high-level inhibitory activity against melanin synthesis. Among them, 5-methyl-2-(methylethyl)phenyl (2Ε)-3-(3,4,5-trimethoxyphenyl)prop-2-enoate (Melasolv)$^{TM}$ 4h, showed the most potent depigmenting effect ($IC_{50}$/ = 10$\mu$M) with low cytotoxicity ($IC_{50}$/ = 200$\mu$M). To find the inhibition mechanism of our candidate, various in vitro tests were performed such as DPPH assay, tyrosinase activity in mushroom or in culture cell and expression of tyrosinase, TRP-l and TRP-2. The result of this study suggested that 4h inhibited melanin synthesis by reducing the expression of tyrosinase and TRP-l at the transcriptional level in melan-a melanocytes.s.

• Journal of the Korean Society of Safety
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• v.2 no.1
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• pp.17-29
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• 1987

The extraction mechanism of Zinc from aqueous solution with D2EHPA (Di-2-Ethylhexyl Phosphoric Acid) dissolved in Kerosene was studied by the single drop method. The effect of the concentrations of reactant species on the extraction rate, Zinc and hydrogen ion in the continuous phase and D2EHPA in the dispersed, was studied for the drop rise period by the experiment. Then a theoretical analysis on the basis of Handlos-Baron modle was carried out. It becomes clear that the extraction rate was controlled by the neutral complex forming reaction at the drop surface from both analysises. From effect of the concentrations of species on the reaction rate, the extraction rate at the drop surface is considered to be as follows. $${\gamma}_{pn}=9.42{\times}10^{-7}\;\frac{[Zn^{2+}][(HR)_2]^{3/2}}{[H^+]^{3/2}}$$

• ETRI Journal
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• v.34 no.4
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• pp.518-526
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• 2012

This paper proposes LC voltage-controlled oscillator (VCO) phase-locked loop (PLL) and ring-VCO PLL topologies with low-phase noise. Differential control loops are used for the PLL locking through a symmetrical transformer-resonator or bilaterally controlled varactor pair. A differential compensation mechanism suppresses out-band spurious tones. The prototypes of the proposed PLL are implemented in a CMOS 65-nm or 45-nm process. The measured results of the LC-VCO PLL show operation frequencies of 3.5 GHz to 5.6 GHz, a phase noise of -118 dBc/Hz at a 1 MHz offset, and a spur rejection of 66 dBc, while dissipating 3.2 mA at a 1 V supply. The ring-VCO PLL shows a phase noise of -95 dBc/Hz at a 1 MHz offset, operation frequencies of 1.2 GHz to 2.04 GHz, and a spur rejection of 59 dBc, while dissipating 5.4 mA at a 1.1 V supply.

• Journal of Life Science
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• v.25 no.1
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• pp.1-7
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• 2015

Cyclin D is a member of the cyclin protein family, which plays a critical role as a core member of the mammalian cell cycle machinery. D-type cyclins (D1, D2, and D3) bind to and activate the cyclin-dependent kinases 4 and 6, which can then phosphorylate the retinoblastoma tumor suppressor gene products. This phosphorylation in turn leads to release or derepression of E2F transcription factors that promote progression from the G1 to S phase of the cell cycle. Among the D-type cyclins, cyclin D3 encoded by the CCND3 gene is one of the least well studied. In the present study, we have investigated the biochemistry of the proteolytic mechanism that leads to loss of cyclin D3 protein. Treatment of human prostate carcinoma PC-3-M cells with lovastatin and actinomycin D resulted in a loss of cyclin D3 protein that was completely reversible by the peptide aldehyde calpain inhibitor, LLnL. Additionally, using inhibitors for various proteolytic systems, we show that degradation of cyclin D3 protein involves the $Ca^{2+}$-activated neutral protease calpain. Moreover, the half-life of cyclin D3 protein half-life increased by at least 10-fold in PC-3M cells in response to the calpain inhibitor. We have also demonstrated that the transient expression of the calpain inhibitor calpastatin increased cyclin D3 protein in serum-starved NIH 3T3 cells. These data suggested that the function of cyclin D3 is regulated by $Ca^{2+}$-dependent protease calpain.

• The Transactions of the Korean Institute of Electrical Engineers B
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• v.51 no.5
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• pp.234-241
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• 2002

An optical pickup actuator is an objective-lens-moving mechanism that provides a means to follow the disk displacement accurately(1). In this paper, a slim type optical pickup actuator for Notebook PCs is analyzed and designed to improve the driving sensitivity A three dimensional equivalent magnetic circuit network method (3D-EMCN method) is proposed for an analysis method which provides better characteristics in both precision and computation time of analysis comparing with a commercial three-dimensional finite element (3D-FEM) codes. To verify the validity of proposed method, we made a comparison between the analysis results and the experimental ones. We also compared this analysis results with 3D-FEM results. Among the several optimal algorithm, we adopt a niching genetic algorithm, which renders a set of the multiple optimal solutions. RCS (Restricted Competition Selection) niching genetic algorithm is used for optimal design of the actuator's performance. Recently, the pickup actuator needs additional driving structure for radial and tangential tilting motion to obtain better pick-up performance. So we applied the proposed method to the model containing tilting coils.