• Proceeding of Spring/Autumn Annual Conference of KHA
• /
• 2011.04a
• /
• pp.226-230
• /
• 2011

The purpose of this study was to investigate the living environment design of orphanage based on universal design. The 3 orphanages which were rebuilded recently was selected and evaluated by checklists. The checklists which are based on 'Universal Design Principles' are consist of 120 items. The major results are summarized as follows: 1) The items related to safety were insufficient such as separation of pedestrian passage, rounded edge. 2) The items related to accessibility were high grade such as width of corridor, curb height. 3) Private zones for sleep, study and storage are needed more and living room is needed more furnitures for activities to increase friendship in the family of orphanage. The results will be expected to make contributions to developing orphanage environment design based on universal design, to understanding the nature of universal design paradigm.

• Proceedings of the Korean Society of Precision Engineering Conference
• /
• 1993.10a
• /
• pp.224-230
• /
• 1993

Closed-die forging of spur gears with hollow cylindrical billet has been analysed by using the upper-bound method. A kinematically admiccible velocity field has been developed. wherein, an involute curve has been introduced to represent the forging die profile. In the analysis, the deformation regions have been divided into nine zones. A constant frictional stress has been assumed on the contacting surfaces. Utilizing the formulated velocity field, numerical calcuations have been carried out to investigate the effects of various parameters, such as module, number of teeth and friction factor,on the forging of spur gears.

• BMB Reports
• /
• v.51 no.5
• /
• pp.230-235
• /
• 2018

Bone resorption by multinucleated osteoclasts is a multistep process involving adhesion to the bone matrix, migration to resorption sites, and formation of sealing zones and ruffled borders. Macrophage colony-stimulating factor (M-CSF) and osteopontin (OPN) have been shown to be involved in the bone resorption process by respective activation of integrin ${\alpha}v{\beta}3$ via "inside-out" and "outside-in" signaling. In this study, we investigated the link between signal modulators known to M-CSF- and OPN-induced osteoclast adhesion and spreading. M-CSF- and OPN-induced osteoclast adhesion was achieved via activation of stepwise signals, including integrin ${\alpha}v{\beta}3$, $PLC{\gamma}$, $PKC{\delta}$, and Rac1. Osteoclast spreading induced by M-CSF and OPN was shown to be controlled via sequential activation, consistent with the osteoclast adhesion processes. In contrast to osteoclast adhesion, osteoclast spreading induced by M-CSF and OPN was blocked via activation of $PLC{\gamma}/PKC{\alpha}/RhoA$ signaling. The combined results indicate that osteoclast adhesion and spreading are selectively regulated via $PLC{\gamma}/PKC{\alpha}-PKC{\delta}/RhoA-Rac1$ signaling.

• Journal of the Mineralogical Society of Korea
• /
• v.17 no.1
• /
• pp.99-114
• /
• 2004

Mineralogical characteristics of fracture-filling minerals from deep borehole in the Yuseong area were studied for the radioactive waste disposal project. There are many fracture zones in the deep drill holes of the Yuseong granite, which was locally affected by the hydrothermal alteration. According to the results of hole rock analysis of drill core samples, $SiO_2$ contents are distinctly decreased, whereas $Al_2$$O_3$ and CaO contents and L.O.I. values are increased in the -90 m∼-130 m and -230 m∼-250 m zone, which is related to the formations of filling minerals. Fracture-filling minerals mainly consist of zeolite minerals (laumontite and heulandite), calcite, illite ($2M_1$ and 1Md polytypes), chlorite, epidote and kaolinite. The relative frequency of occurrence among the fracture-filling minerals is calcite zeolite mineral > illite > epidote chlorite kaolinite. Judging from the SEM observation and EPMA analysis, there is no systematic change in the texture and chemical composition of the fracture-filling minerals with depth. In the study area, low temperature hydrothermal alteration was overlapped with water-rock interactions for a long geological time through the fracture zone developed in the granite body. Therefore the further study on the origin and paragenesis of the fracture-filling minerals are required.

• Applied Microscopy
• /
• v.34 no.4
• /
• pp.223-230
• /
• 2004

To identify the structural basis of mutations that affect synaptic transmission we have begun quantitative ultrastructural descriptions of synapses in cultured Drosophila embryonic neurons. In wild-type cultures, synapses are distinguished by the parallel arrangement of a thickened pre- and post synaptic membrane separated by a synaptic cleft. The presynaptic active zones and postsynaptic densities are defined by electron dense material close to the membrane. Presynaptic regions are also characterized by the presence of one or more electron dense regions, presynaptic densities, around which a variable number of small, clear core synaptic vesicles (mean $35.1{\pm}1.44$ nm in diameter) are clustered. Subsets of these vesicles are in direct contact with either the presynaptic density or the membrane and are considered morphologically docked. A small number of larger, dense core vesicles are also observed in most presynaptic profiles.

• Journal of Wetlands Research
• /
• v.12 no.3
• /
• pp.145-153
• /
• 2010

An-yang stream is a branch stream connecting to Han river and regarded as a national stream. This study chose the representative stream of An-yang and identified vegetation and flora. The ecological survey aimed at identifying indicator of urban streams for measuring to protect urban areas and to promote wetland conservation. A total of 266 species were identified into 35 Orders, 78 Families. The introduced species of Sicyo angulatus need a special treatment to reduce the population. The wetland vegetation is quite various and we suggested 11 different vegetation zones depending on introduced species and amenity between human and nature, This will lead to blue-network to crease favorable environment and manage important species for this region.

• KSCE Journal of Civil and Environmental Engineering Research
• /
• v.28 no.4C
• /
• pp.221-230
• /
• 2008

The George Massey immersed tunnel passes the Fraser River near Vancouver, Western Canada. The tunnel was founded on sandy soils and its behavior during earthquake was analyzed by an effective stress constitutive model called UBCSAND. This model is able to calculate pore pressure rise and resulting tunnel movements due to cyclic loading. Centrifuge tests conducted at Rensselaer Polytechnic Institute (RPI) were used to verify the model performance. The centrifuge tests consisted of 2 models: Model 1 was designed for an original ground condition, Model 2 for a ground improvement by densification. In Model 1, large deformation of the tunnel was observed due to liquefaction of surrounding soil. Because of the densified zones around the tunnel the vertical and horizontal displacements of the tunnel in Model 2 was 50% less than Model 1. Measured excess pore pressures, accelerations, and displacements from centrifuge tests were in close agreement with the predictions of UBCSAND model. Therefore, the model can be used to predict seismic behavior of immersed tunnels on sandy soils and optimize liquefaction remediation methods.

• The Journal of Engineering Geology
• /
• v.21 no.3
• /
• pp.221-230
• /
• 2011

The movement of rock cut slopes may result in upheaval of an adjacent road. Because most cut slopes consist of rock, road upheaval due to the movement of a cut slope is a rare phenomenon in Korea. We found that the movement of rock slopes which are heavily weathered and with strongly developed weak zones is governed by circular failure of the overall rock formation rather than by failure along discontinuities. The results of a numerical analysis revealed that the application of a ubiquitous joint model in a continuum analysis is appropriate for anisotropic rocks (e.g., schist) and for slopes for which the stability is influenced by a particular discontinuity. The results of a field investigation and numerical analyses suggest that retaining walls and anchors should be used to stabilize rock slopes and that real-time monitoring equipment should be installed to assess the reinforcing effect of the remedial measures.

• Geophysics and Geophysical Exploration
• /
• v.9 no.3
• /
• pp.225-230
• /
• 2006

Fluid replacement and conductivity logging have been applied to three boreholes in coastal aquifer in order to identify permeable fractures and to estimate the origin of saline groundwater. Fluid replacement technique measures and monitors the change of borehole fluid conductivity with depth under ambient or pumping condition after replacing the original borehole fluid with different one (by pumping out original one and injecting simultaneously new one at the hole bottom). After the replacement of borehole fluid, the change of fluid conductivity can be the direct indicator of the intake flow of formation water through aquifer such as permeable fractures or porous formations. The conductivity profiles measured with times therefore indicate the locations of permeable zone or fractures within the open hole or the fully slotted casing hole. As a result of fluid conductivity logging for three boreholes at coastal area in Yeonggwang, Jeonam Province, it is interpreted that the seawater intrusion in this area is not by remnant saline groundwater after land reclamation but mainly by intrusion of saline water through fractured rock. This approach might be useful for assessing the characteristics of seawater intrusion, the design of optimal pumping, the mitigation of seawater intrusion using freshwater injection, and estimating the hydraulic characteristics in coastal aquifer.

• Journal of Life Science
• /
• v.29 no.2
• /
• pp.223-230
• /
• 2019

Ozone is a gaseous molecule able to kill microorganisms, such as yeast, fungi, bacteria, and protozoa. However, ozone gas is unstable and cannot be used easily. In order to utilize ozone properly and efficiently, plant oil can be employed. Ozone reacts with C-C double bonds of fatty acids, converting to ozonized oil. In this reaction, ozonide is produced within fatty acids and the resulting ozonized oil has various biological functions. In this study, we showed that ozonized oil has antimicrobial activity against fungi and bacteria. To test the antimicrobial activity of ozonized oil, we produced ozonized olive oil. Ozonized olive oil was applied to Staphylococcus aureus, methicillin-resistant Staphylococcus aureus (MRSA), Staphylococcus epidermidis, Pseudomonas aeruginosa, Escherichia coli, and Candida albicans. Antimicrobial activity was assayed using the disk diffusion method following the National Committee for Clinical Laboratory Standards. Minimal inhibitory concentrations (MIC) were 0.25 mg for S. aureus, 0.5 mg for S. epidermidis, 3.0 mg for P. aeruginosa, and 1.0 mg for E. coli. Gram positive bacteria were more susceptible than Gram negative bacteria. We compared growth inhibition zones against S. aureus and MRSA, showing that the ozonized olive oil was more effective on MRSA than S. aureus. Furthermore, the ozonized olive oil killed C. albicans within an hour. These data suggested that ozonized olive oil could be an alternative drug for MRSA infection and could be utilized as a potent antimicrobial and antifungal substance.