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The XRCC1 Arg280His Gene Polymorphism and Hepatocellular Carcinoma Risk: A Meta-analysis

  • Li, Lu-Ping;Wu, Wei;Li, Xing-Hai;Song, Shu-Sen
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.3
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    • pp.2033-2036
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    • 2013
  • Many studies have suggested that the XRCC1 Arg280His gene polymorphism might be involved in the development of hepatocellular carcinoma (HCC). However, the results have been inconsistent. In this study, the authors performed a meta-analysis to assess the association between XRCC1 Arg280His and HCC susceptibility. Published literature from PubMed, EMBASE and CNKI Data was searched. Pooled odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using fixed- or random-effects models when appropriate. Begg's test was used to measure publication bias. A total of 7 case-control studies covering 1,448 HCC cases and 1,544 controls were included. No significant variation in HCC risk was detected in any of the genetic models overall. In the stratified analysis, four studies with sample sizes over 300 produced similar results. The corresponding pooled ORs were not substantially altered after the exclusion of three studies deviating from Hardy-Weinberg equilibrium in the control group, which indicated reliability for our meta-analysis results.

A Study of Vibration Analysis Due to Structual Changes of Dynamic Structure (동적 구조물의 구조변화에 의한 진동해석 연구)

  • 현천성;이기형;정인성
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.16 no.11
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    • pp.2033-2048
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    • 1992
  • This paper presents the theoretical development and qualitative evaluation of a new concept in the mathematical modeling of dynamic structures. We use both test data and analytical approximations to identify the parameters of an incomplete model. The model has the capability of predicting the response of the points of interest on the structure over the frequency range of interest and can be used to predict the changes in natural frequencies and normal modes due to structural changes. The theory was tested by running simulated tests on a relatively simple structure, identifying the parameters of the incomplete model, and using this model to predict the effects on frequency and mode shapes of several mass and stiffness changes. The conditions of the tests were varied by selecting different numbers of points of measurement, varying the frequency range, and by including assumed measurement error. It is recommended that the theoretical development be continued and that applications to more complex structures be carried out in order to develop a better understanding of the limitations and capabilities of the method. A successful, more definitive sevaluation could lead to immediate practical applications.

Ground Organic Monolith Particles Having a Large Volume of Macropores as Chromatographic Separation Media

  • Lee, Jin Wook;Ali, Faiz;Kim, Yune Sung;Cheong, Won Jo
    • Bulletin of the Korean Chemical Society
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    • v.35 no.7
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    • pp.2033-2037
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    • 2014
  • A reaction mixture was developed for formation of soft organic monolith that was easily smashed, rinsed, refluxed, filtered, and dried to give monolith particles having high pore volume of macropores. This phase was almost without mesopores. The reaction mixture was composed of methacrylic acid, ethylene glycol dimethacrylate, polyethylene glycol (porogen), and an initiator in a mixed solvent of toluene and isooctane. The selection of porogen and its amount was carefully carried out to obtain the optimized separation efficiency of the resultant phase. The median macropore size was 1.6 ${\mu}m$, and the total pore volume was 3.0-3.4 mL/g. The median particle size (volume based) was 15 ${\mu}m$, and the range of particle size distribution was very broad. Nevertheless the column (1 ${\times}$ 300 mm) packed with this phase showed good separation efficiency (N~10,000-16,000) comparable to that of a commercial column packed with 5 ${\mu}m$ C18 silica particles.

An Implementation for Effective Shielding System of Information Electronic Equipments (정보가전기기의 효과적인 차폐시스템 구현)

  • Kim, Jae-Yee;Jeong, Jong-Wook
    • Proceedings of the KIEE Conference
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    • 2004.07c
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    • pp.2031-2033
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    • 2004
  • In this paper, electromagnetic wave environment generated from electronic equipments was investigated. Since the main source of electromagnetic waves are electronic equipments, the field intensity of a harmful electromagnetic wave was measured and its harmful level was analyzed. It was also found that the result was 23%${\sim}$38% in case of TV set and microwave oven. Based on this analysis, this study proposed efficient shielding method to suppress unwanted electromagnetic wave.

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Terahertz reflection nondestructive test by time analysis and short-time Fourier analysis (시간 분석 및 짧은 시간 구간별 주파수 분석을 이용한 반사형 테라헤르츠파 비파괴 검사)

  • NamGung, Chan;Cho, Sang-Heum;Ahn, Chang-Beom
    • Proceedings of the KIEE Conference
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    • 2011.07a
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    • pp.2033-2034
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    • 2011
  • 본 논문에서는 물체 내부를 파괴하지 않고 검사 할 수 있는 방식 중에 인체에 무해한 테라헤르츠파를 이용하여 짧은 시간 영역과 짧은 시간 주파수 영역을 분석하고, 집적회로 샘플을 대상으로 실험하였으며 짧은 시간 주파수 영역을 분석함으로써 비파괴 검사를 할 수 있다는 가능성을 제시하였다.

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Efficient Huffman decoder using octal tree search algorithm (효율적인 8진 트리 검색 방식의 허프만 복호화기 구현)

  • 우광희;김구용;한헌수;차형태
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.25 no.12B
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    • pp.2033-2038
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    • 2000
  • 여러 가지 압축알고리즘 중에서 허프만 부호화는 데이터의 통계적인 중복성을 제거하기 위한 방법으로 많이 사용되어 왔다. 이제까지 허프만 테이블의 특성과 코드워드의 패턴에 따라 효율적으로 복호화할 수 있는 알고리즘이 많이 제안되었다. 본 논문에서는 8진 트리 검색 방법을 이용한 허프만 복호화 알고리즘을 제안하고 효율적인 하드웨어 구현 방법을 제안한다. 하드웨어의 메모리와 게이트 면적을 소형화하였고 빠른 검색을 위하여 알고리즘을 최적화하여 MPEG 오디오 복호화기 시스템에 적용할 수 있게 하였다.

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Management of Vertical Control Points by Vector Method for Determination of Highway and Railroad Vertical Alignment (도로 및 철도의 종단선형 탐색을 위한 벡터방식의 Vertical Control Point 처리기법 연구)

  • Kim, Jeong Hyun;Han, Chang-Gun
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.33 no.5
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    • pp.2033-2040
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    • 2013
  • There have been noticeable developments for the optimization of the highway and railroad alignments with the IT and computerized tools. The designers expect that all of the quantitative design elements should be considered. This study developed a methodology which can be useful for the vertical alignment design. It provides a accurate "vertical control point" searching method, and makes the vertical alignment optimization more efficiently. The vector method makes the searching faster and calculates more accurate application sections. The results from this method generate more reliable vertical alignments than the conventional raster method for less computation time.

A Study on the Characteristics of Minimalism on GUI in Game (게임 그래픽 유저 인터페이스(GUI)의 미니멀리즘(Minimalism) 특성에 관한 연구)

  • Kim, Yun-Kyung
    • Cartoon and Animation Studies
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    • s.31
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    • pp.249-266
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    • 2013
  • The purpose of this research is to study a case of the minimalism on Game Graphic User Interface design in Computer game. It is to analyse the minimal tendency on Game Graphic User Interface design in several Computer games such as Prince of Persia, Mirror's Edge, Splinter Cell, Gears of War, Call of Duty4, Metro 2033, Crysis2. These games expanded the field of Game Graphic User Interface design with the unique form of minimalism. Minimalism came from the formative arts in the 1960s and influenced to other fields of art. It seems to be an expression of various styles that promptly meet the needs of the times. Therefore, in this research, I would highlight the phenomenon of minimalisation in Game Graphic User Interface design and research the influence of Minimalism that appears in modern design focused on "simplicity" and "minimum" which are representative trend of Minimalism.

A Meta-Analysis of Influencing Collagen Intake on Skin Utilizing Big Data (빅데이터 분석을 활용한 콜라겐 섭취가 피부에 미치는 영향에 관한 메타분석)

  • Jin, Chan-Yong;Yu, Ok-Kyeong;Nam, Soo-Tai
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.20 no.11
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    • pp.2033-2038
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    • 2016
  • Big data analysis, in the large amount of data stored as the data warehouse which it refers the process of discovering meaningful new correlations, patterns, trends and creating new values. The important issue of a meta-analysis is not the significance test, the effect size of the predictor variable on the criterion variable. We reviewed a total of 236 samples among 6 studies published on the topic related Collagen intake on skin between 2000 and 2016 in Korea. The results of the study are summarized as follows. First, we concluded that the path between before and after of Sebum (SB) had the largest effect size of (r = .416) Therefore, the effect of the Collagen intake intervention showed an explanatory power of 17 (%) about. Next, the path between before and after of Moisture (MS) had the higher the effect size of (r = .318). Thus, we present the theoretical and practical implications of these results.