• Toxicological Research
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• v.34 no.1
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• pp.55-63
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• 2018

As a part of general toxicity studies of Enterococcus Faecalis 2001 (EF 2001) prepared using heat-treatment bacillus mort body EF 2001 in mice, this study examined the toxicity of EF 2001 in single and repeated administrations following the previous report in order to apply this product to preventive medicine. The safety of oral ingestion of EF 2001 was examined in 6-week-old male and female ICR mice with 1,000 mg/kg, 3,000 mg/kg and 5,000 mg/kg body weight/day administrated by gavage of the maximum acceptable dose of EF 2001. The study was conducted using distilled water as a control following the methods for general toxicity studies described in the "Guidelines for Non-clinical Studies of Pharmaceutical Products 2002". As a control, 1) observation of general conditions, 2) measurement of body weight, 3) determination of food consumption, 4) determination of water consumption, 5) blood test and urinalysis and 6) pathological examination were performed for the administration of EF 2001. Mice received EF 2001 for 13 weeks and results were compared with those of the control group that received distilled water. The results of the above examinations revealed no significant differences between control and EF 2001 groups for both males and females. Thus, no notable toxicity was confirmed with single and repeated oral administrations of EF 2001. Oral administration in the above doses did not result in abnormal symptoms or death during the observation period. No abnormalities in blood cell count or organ weights were seen. Without any evidence of toxicity to cells and organs, EF 2001 is speculated to not adversely affect living organisms. The 50% lethal dose of EF 2001 with oral administration in mice is estimated to be greater than 5,000 mg/kg body weight/day for both male and female mice. Therefore, $LD_{50}$ value for animals was 5,000 mg/kg or more.

• The KIPS Transactions:PartA
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• v.10A no.3
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• pp.239-246
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• 2003

The Verilog parser libary for IEEE Verilog 1364-2001 Standard is developed in the paper. The lexer and scanner are developed and tested to handle "Yerilog-2001" which is the first major update to the Verilog language since its inception in 1984. Also the newly developed XML intermediate format for Verilog-2001 is presented. By using the XML intermediate, it allows the portable and scalable development of various kinds of verilog applications that are mainly focused on semantic manipulation.ipulation.

• Journal of the Korean earth science society
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• v.22 no.5
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• pp.448-448
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• 2001

• Journal of the Korean Dietetic Association
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• v.9 no.1
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• pp.47-56
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• 2003

Currently, dietary life in Korea is rapidly changing. New food from other countries introduced to the diet with changing economic and social environment. The number of meals away from home is increasing. Also, number of students who served by the school food service are increasing. In this paper, the menu in the school food service are compared between 1995 and 2001. Analysis was done to see changes in the use of Korean traditional foods. Between July, 2001 and August, 2001, by mail 103 schools were surveyed to analyzed menu. Menu from 2001 survey are compared with menu from 1995 survey. The results are following; 1) New menus are introduced in 2001 compared with 1995. 2) The number of menu using animal foods are increasing in 2001. 3) Among cooking methods, stir frying, and deep frying, are used more in 2001 than that of 1995. 4) The number of Korean dish served are decreased in 2001. 5) Students favorite dish are changed. Students like dishes cooked with deep frying method and western foods. With these results, menu of school food services become more westernized and using more frying methods because of students' taste preference. These trend are not recommendable for the students health, because it is known that Korean traditional dishes are more healthful. There should be more research and effort to keep Korean tranditional foods in the menu of the school food service for students health.

• Health Policy and Management
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• v.27 no.4
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• pp.372-374
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• 2017

Korea is one of the fastest aging country in the world. The increase in health expenditure is an inevitable problem in an aging country. We examined trend of benefit expenditure in National Health Insurance (NHI) by age group during 2001 to 2016. The benefit expenditure of NHI was 13.0 trillion won (2001) and 48.7 trillion won (2016); that is 3.76 times to 2001. This rapid increase was mostly due to people aged 65 and over. Proportion of beneficiaries aged 65 and over was 6.9% (2001) and 13.7% (2016), benefit expenditure per capita aged 65 and over was 279 thousand won (2001) and 960 thousand won (2016), and utilization days per capita aged 65 and over 21.44 (2001) and 30.23 (2016). This phenomenon was more pronounced in 75 or 85 aged and over. To contain the health costs for older people, the NHI system should be reformed.

• Journal of the Korean Society of Industry Convergence
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• v.16 no.2
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• pp.35-39
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• 2013

This paper synthesized the new copper removal agent(PW-2001) and investigated removal efficiency of copper, COD, calcium, SS and sludge amounts. Removal efficiency of copper were 96.1% and 99.1% with the lime and PW-2001, respectively while COD removals reached up to 38% and 69.6% with the use of lime and PW-2001. The concentrations of calcium and SS with PW-2001 were decreased 2.68 and 4.95 times lower than those with lime. Amount of sludge with PW-2001 was 60% smaller than lime. Quantity of PW-2001 needed for coagulation only reached 58.7, compared to lime standard quantity(100), and total cost of copper removal with PW-2001 was saved 25% more than lime.

• Research in Plant Disease
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• v.8 no.4
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• pp.239-244
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• 2002

Among 34 isolates of Colletotrichum spp., 20 from red pepper and 14 from apple, only one isolate 2001-45 was identified as the isolate resistant to sterol biosynthesis inhibiting fungicides. EC$_{50}$ values of the isolate 2001-45 were 153.5, 42.7, 34.0, and 17.1 $\mu\textrm{g}$/ml for myclobutanil, tebuconazole, hexaconazole and nuarimol, respectively, The resistance factor of the isolate 2001-45 against the other isolate 2001-44 to 4 above fungicides was ranged from 17 to 57. However, EC$_{50}$ value of the 2001-45 for prochloraz was 0.07 $\mu\textrm{g}$/ml, which was lower than those of the 2001-44 and the isolate JC24. For the fitness test of the 2001-45, mycelial growth, sporulation on PDA and pathogenicity on fruits were investigated. No difference in mycelial growth was found between 2001-45 and 2001-44, but great difference in sporulation. No symptom was developed by 2001-45 even by wound inoculation of pepper fruit. Therefore, this study indicated that the isolate 2001-45 was inferior to the other isolates in the fitness, although the isolate 2001-45 was highly resistant to sterol biosynthesis inhibiting fungicides.

• RED RIBBON
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• s.43
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• pp.30-31
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• 2001

2001년 유엔에이즈(UNAIDS)가 발표한 자료에 따르면, 전 세계 국가 중 약 40%는 HIV나 에이즈 감염자 실태 파악을 위한 감독 체계가 '전혀 없거나', 있다 하더라도 '제 기능을 하지 못하는' 것으로 나타나 에이즈 관리에 대한 각국의 노력이 더욱 필요한 실정이다.

• 한우마당
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• v.2 no.3 s.8
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• pp.50-50
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• 2001

• The monthly packaging world
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• s.98
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• pp.134-137
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• 2001