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Immune Reconstitution Inflammatory Syndrome-Like Reaction During the Treatment of Pneumocystis jirovecii Pneumonia in an Infant With Severe Combined Immunodeficiency

  • Ching-Yu Lin;Sung-Min Lim;Soo-Yeon Kim;Seung-Min Hahn;Jong-Gyun Ahn;Ji-Man Kang
    • Pediatric Infection and Vaccine
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    • v.31 no.1
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    • pp.130-135
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    • 2024
  • The effectiveness of corticosteroids in preventing immune reconstitution inflammatory syndrome in non-human immunodeficiency viruses Pneumocystis carinii pneumonia (PCP) patients, such as severe combined immunodeficiency (SCID) patients, is controversial. We experienced a paradoxical reaction during severe PCP treatment in a SCID infant, which responded well to adjuvant corticosteroids.

The Problems in Digital Watermarking into Intra-Frames of H.264/AVC (H.264-기반 인트라 프레임의 디지털 워터마킹 문제)

  • Choi, Hyun-Jun;Seo, Young-Ho;Kim, Dong-Wook
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.13 no.2
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    • pp.233-242
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    • 2009
  • This paper intend to show the affect of the intra-prediction on the typical digital watermarking method and the fact that the watermarking method has very low effectiveness when it is performed for the intra-frames of H.264. The target watermarking method was the one for imperceptibility and robustness and was assumed to be performed during the intra-compression process by the H.264 technique. Also this method was assumed to insert watermark data and to extract it for certification if needed. The problem is that the resulting data from the re-engineering of the watermark insertion process to extract the watermark data is different from the one before. We experimentally showed that it stems from the intra-prediction itself. That is, we showed that the resulting image data from only compression without watermarking changes if it is re-compressed by the same conditions as the first compression and it is because the intra-prediction modes as well as the coefficient values change. Also, we applied one blind and one semi-blind watermarking methods to show that the typical attacks after watermarking makes this problem much more serious and lowers the effectiveness of the watermarking method dramatically. Therefore we concluded by considering the experimental data that a typical watermarking method which has been researched so far cannot guarantee the effectiveness of intra-frame watermarking and it is highly required to developed a new kind of methodologies.

The Study of Utilty to 'Rolly Poly 160', Type II diabetes self-management Serious Game, Using Satisfaction Analysis (제2형 당뇨 식이 기능성 게임 '롤리폴리 160'의 효용성 및 만족도 조사 연구)

  • Ahn, Tae-Hong;Yu, Mi-Sun
    • Journal of Korea Game Society
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    • v.19 no.6
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    • pp.107-116
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    • 2019
  • A diabetes self-management serious game, 'Roly Poly 160' is developed for Type II diabetes patients to decrease their blood Sugar level. For verifying the effectiveness of 'Roly Poly 160', we examined the satisfaction survey. Data were collected from the diabetes patients and public those who have used 'Roly Poly 160' through D Community health center and S Community health center in Gwangju, from November, 27, 2018 to December, 4, 2018. 67 people returned the survey through the 'Roly Poly 160' APP. The overall average satisfaction level was 3.7 out of 5.

태양열 구동 흡수식 냉방 시스템 실증

  • Gwak, Hui-Yeol
    • 한국신재생에너지학회:학술대회논문집
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    • 2005.11a
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    • pp.353-362
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    • 2005
  • 태양열시스템은 하절기에 급탕과 난방 부하가 적거나, 거의 없어 시스템의 과열 문제가 야기 될 수 있다. 이를 해결하는 방안 중에 하나로 흡수식 냉방시스템을 이용하여 하절기 잉여열원을 활용하여 냉방하는 방법이 대두되고 있다. 태양열 냉방시스템은 전기에너지를 대체하는 효과 뿐 아니라 태양열 연간 이용 효율 극대화에도 크게 기여 할 수 있다. 본 고에서는 국내 기술로 최초로 개발 실용화된 중온용 단일 진공관형 태양열 집열기와 1중 효용 흡수식 냉방기를 이용하여 실증연구를 계획하였다. 태양열 냉방 실증을 위하여 단일 진공관형 태양열 집열기 집열면적 200m2, 축열조(태양열, 급탕, 냉수), 10RT급 냉방기, 냉각탑, 보조 보일러, 원격 제어 및 모니터링 등이 계획 되었다. 실증시험 중간 결과 태양열 냉방시스템은 하절기 맑은 날 하루 동안 약 5 - 6시간 안정적으로 가동 되었으며, 앞으로 온수급탕, 난방 시험을 거쳐 시스템 성능 및 경제성 평가를 통하여 유용성, 안정성 및 신뢰성이 검증 될 계획이다.

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A Study on the Crack Detection using Eigenfrequency Test Data (고유진동수를 이용한 균열탐색에 관한 연구)

  • 정명지;이영신
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 1994.10a
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    • pp.187-191
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    • 1994
  • 기계구조물내의 균열은 고하중상태에서 갑작스러운 파괴의 주요 원인의 하나로서 이러한 균열의 조기탐지를 위해 기존의 비파괴검사 방법 이외에, 최근 진동측정 및 진동분석을 이용하는 방법이 경제성 및 그 효용성으로 인하여 깊게 연구되고 있다. 이러한 진동특성의 변화를 이용하여 균열을 탐지하는 방법이 많은 학자들에 의해 연구되어졌으며, 현재까지의 연구결과중 균열의 크기 및 위치를 동시에 탐지할 수 있는 방법중에서 비교적 단순, 정확하다고 판단되는 방법으로는 임의의 두 지점에서의 진폭측정을 이용한 Rizos(1)의 방법과 고유진동수 및 모우드형 측정을 이용한 Kam & Lee(2)의 방법이 있으나 이들 방법은 두가지 이상의 진동특성치를 요구하고 있다. 본 연구의 목적은 진동특성치중 고유진동수만을 이용하여 단순부재에서 균열의 크기 및 위치를 수치적으로 예측할 수 있는 새로운 해석기법을 제시하고, 기존 방법 사용시의 결과와 비교 검토하여 그 유용성을 판단하는데 있다.

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A MODEL SYSTEM FOR NON-WORKER'S DAILY TRAVEL DEMAND BASED ON DISAGGREGATE BEHAVIOURAL MODEL (개별 로짓 모형을 이용한 비취업자의 1일 통행행태에 관한 연구)

  • 배영석;김태웅
    • Journal of Korean Society of Transportation
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    • v.8 no.1
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    • pp.89-102
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    • 1990
  • 본 연구에서는 개별모형(disaggregate model)을 이용한 도시권의 교통수요예측 모형체계의 구축을 최종목적으로 하며, 그때 개인이 1일 중에 행하는 복수의 트립에 관한 의사결정간의 상호관계를 적절히 고려함에 의해, 되도록 개인의 교통행동을 논리적으로 설명함과 동시에 모형의 취급이 용이하도록 논리성과 실용성이 잘 조화된 모형의 구축을 시도하였다. 모형의 체계는 비취업자와 취업자 각각의 1일의 통행행태유형의 선택에 관한 2개의 Sub-model로 구성되어져 있다. 본 논문은 그 Sub-model중의 하나인 비취업자의 1일의 통행행태유형(트립발생, 각 트립의 목적지와 교통수단)의 선택에 관한 개별모형의 개발을 행한 것이다. 본 모형의 특징은 tour별 효용최대화행동가설에 기초를 두어 개인이 1일 중에 행하는 각 트립의 선택행동은 해당트립의 전후에 행해지는 트립들의 선택행동의 영향을 고려하여 의사결정을 하는 것으로 가설을 설정하여 트립간의 상호관련성을 표현하였다. 모형의 구조로서는, 모형의 취급이 보다 용이하도록 tour별 효과최대화를 트립단위의 단계형 모형으로 표현하는 nested logit model형의 수차동시효과최대화 모형을 구축하였다 실제의 도시권에 대한 실증적 검토를 행한 결과, 본 연구에서 개발한 별개모형의 유효성이 확인되었다.

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Economic evaluation of a weekly administration of a sustained-release injection of recombinant human growth hormone for the treatment of children with growth hormone deficiency (소아 성장호르몬결핍증 치료에 사용되는 성장호르몬 서방형 주사제의 경제성 평가)

  • Kang, Hye-Young;Kim, Duk Hee;Yang, Sei-Won;Kim, Yoon-Nam;Kim, Miseon
    • Clinical and Experimental Pediatrics
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    • v.52 no.11
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    • pp.1249-1259
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    • 2009
  • Purpose:From a societal perspective, we evaluated the cost-effectiveness of a novel sustained-release injection of recombinant human growth hormone (GH) administered on a weekly basis compared with that of the present daily GH injection for the treatment of children with GH deficiency. Methods:Health-related utility for GH therapy was measured based on the visual analogue scale. During July 2008, caregivers of 149 children receiving GH therapy form 2 study sites participated in a web-based questionnaire survey. The survey required the caregivers to rate their current subjective utility with daily GH injections or expected utility of weekly GH injections. Because there was no difference in the costs of the daily and weekly therapies, for the purposes of this study, only drug acquisition costs were considered. Results:Switching from daily to weekly injection of GH increased the utility from 0.584 to 0.784 and incurred an extra cost of 4,060,811 Korean won (KW) per year. The incremental cost-utility ratio (ICUR) for a base case was 20,305,055 KW per quality-adjusted life year (QALY) gained. Scenario analyses showed that the ICUR ranged from 15,751,198 to 25,489,929 KW per QALY. Conclusion:The ICUR for a base case and worst case scenario analyses ranged from 0.85 to 1.37-times per capita gross domestic product of Korea, which is considered to be within the generally accepted willingness-to-pay threshold. Thus, it is concluded that switching from daily to weekly injection of GH would be cost-effective.

A Spot Detection Method in 2D Electrophoresis Images Using Gradients of Spot Boundary (스팟 윤곽의 기울기를 이용한 단백질 2차원 전기영동 영상에서의 스팟 검출 방법)

  • 유혜경;이성환
    • Proceedings of the Korean Information Science Society Conference
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    • 2004.10b
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    • pp.283-285
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    • 2004
  • 단백질 2차원 전기영동은 다양한 단백질 분리 방법 중 가장 널리 쓰이는 방법으로 실험 결과를 촬영한 영상을 분석하여 얻은 단백질 스팟의 위치나 질량, 발현 유무 등을 이용하여 각종 질병의 발생 원인 진행 상태, 생리적인 변화 등에 대해 분석할 수 있다. 실험 영상에 다수의 단백질이 존재하므로 이를 수작업으로 처리할 경우에 많은 시간과 노력이 소요되므로 본 논문에서는 자동화된 단백질 스팟 검출 방법을 제안하였으며 단백질 스팟이 같은 위치에 겹쳐서 나타나는 경우가 많은 단백질 2차원 전기영동 실험 영상의 특성을 고려하여 여러 개의 단백질이 겹쳐진 복잡한 스팟 영역에 대해서 스팟의 형태 정보를 이용하여 스팟의 개수를 추정하고 개별 스팟으로 분리하여 보다 신뢰성 있는 분석이 가능하게 하였다 본 논문에서 제안된 방법의 효용성을 검증하기 위해 기존에 널리 사용되고 있는 상용 소프트웨어와 비교 실험을 수행한 결과 겹친 정도가 60%이상인 경우 기존 방법에 비해 우수한 결과를 보였다.

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Species, Planting Position and Scenic Utilization of 'Paulownia Tree(梧桐)' in the Traditional Garden (전통정원에서 '오동(梧桐)'의 수종, 식재 위치와 경관적 활용)

  • Hong, Hyoung-Soon
    • Journal of the Korean Institute of Traditional Landscape Architecture
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    • v.31 no.2
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    • pp.20-30
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    • 2013
  • 'Paulownia tree', one of a tree species which has been with human civilization, has been widely used as a garden plant. The purpose of this study is to investigate concrete species of 'paulownia tree,' which had been planted in Korean traditional garden, the position of plantation, and consider its usefulness therefrom. The results of the study can be summarized as follows. 1. As the result of considering old literatures as encyclopedia, agricultural book (農書), gardening book, etc., there's a difference in the description of 'paulownia tree' depending on the complier, as well, the classification of concrete species is quite ambiguous. Therefore, it judged a limit which is planted based on point of the compass is not apply to species of tress of paulownia tree. Merely, the point of suitability and evasion(宜忌) related to the plantation of 'paulownia tree' could be identified in "Jeungbosanrimgyeongje(增補山林經濟) and "Imwongyeongjeji(林園經濟志)", not "Sanrimgyeongje (山林經濟)". 2. It could be confirmed again through poetry and prose which describe old garden that the words such as 'O(梧)', 'Dong(桐)', 'Odong(梧桐)', etc. were used without significant division. However, it is supposed that the species 'Odong' which was actually adopted at the garden might be Catalpa as well including Korean Paulownia and Chinese parasol tree. 3. It is considered that the reference point of suitability and evasion(宜忌) regarding 'paulownia tree' plantation was not generally applied. That is, species of paulownia tree was not divided for planting according to direction, as well, they seemed to willingly plant paulownia trees nearby the house as well, e.g. front yard or nearby yard, etc. 4. The usefulness of paulownia tree as a garden plant of an old garden played a role of 'the messenger of fall,' emphasizing a sense of the season. 5. Paulownia tree has another usefulness as a tree which adds an Ephemeral landscape. Therefore, the ancient people considered 'paulownia tree' that goes with 'the moon' the best, and enjoyed the quaint beauty of those two are juxtaposed. Also, 'paulownia tree' was utilized as a tree which adds an atmosphere of a rainy day, such as enjoying the sound of rain dropping on the 'paulownia tree', etc. The limitation of this study is that the research was performed being restricted to the translation among lots of Chinese references. Later-on task of research is the necessity of a more in-depth study through the discover of new historical sources and the accumulation of translation outcome.

Analysis of Thermal Performance of a Solar Heating & Cooling System (태양열 냉.난방시스템의 열성능 분석)

  • Kwak, Hee-Youl;Shin, U-Cheul
    • Journal of the Korean Solar Energy Society
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    • v.28 no.4
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    • pp.43-49
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    • 2008
  • The purpose of this study is to present the simulation results and an overview of the performance assessment of a solar heating & cooling system by means of the $200m^2$ evacuated tube solar collector. The simulation was carried out using the thermal simulation code TRNSYS with new model of a single-effect LiBr/$H_{2}O$ absorption chiller developed by this study. The calculation was performed for yearly long-term thermal performance and for two design factors: the solar hot water storage tank and the cold water storage tank. As a result, it was anticipated that the yearly mean system efficiency is 46.7% and the solar fraction for the heating, cooling and hot water supply are about 84.4 %, 41.7% and 72.4%, respectively.