• Food Science and Preservation
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• v.24 no.7
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• pp.1025-1033
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• 2017

In this study, Ledum palustre L. was extracted by 4 different methods (LPW, hot water extraction; LPA, autoclave extraction; LPU, ultrasonification extraction; LPE, 70% ethanol extraction) and LPE was fractionated by using polarity difference of each solvent and used as 4 samples (LPE/H, the n-hexane layer; LPE/E, the EtOAc layer; LPE/B, the n-BuOH layer; LPE/W, the $H_2O$ layer). Antioxidant activities of Ledum palustre L. extracts were measured by DPPH and ABTS. As a result, the DPPH and ABTS radical scavenging showed high activities with LPE (82.3%, 99.8%) and LPE/E (91.8%, 99.6%) at the concentration of $1,000{\mu}g/mL$. The anti-inflammatory activities of LPE and LPE/E were measured by the inhibitory activity against NO, $PGE_2$, TNF-${\alpha}$, IL-$1{\beta}$ and IL-6 production on LPS-stimulated Raw 264.7 macrophages. As a result of MTT assay, cell viabilities of LPE and LPE/E were more than 90% at $25{\mu}g/mL$. NO and $PGE_2$ productions were inhibited by LPE (NO: 50%, $PGE_2$: 70%) and LPE/E (NO: 57%, $PGE_2$: 73%) at the concentration of $25{\mu}g/mL$. The inhibition activities against TNF-${\alpha}$, IL-$1{\beta}$, IL-6 production were 24%, 47% and 40% at the concentration of $25{\mu}g/mL$ of LPE. In particular, LPE/E showed 51%, 57% and 62% inhibition activities at the same concentration, respectively. From the above results, it can be concluded that $1,000{\mu}g/mL$ of LPE and LPE/E have the high antioxidant activities similar with Vitamin C, and $25{\mu}g/mL$, the low concetration of LPE and LPE/E have excellent anti-inflammatory activities. Therefore, if more research about anti-aging, whitening and antimicrobial activity of Ledum palustre L. extracts is carried out in the future, it will be possible to use them as effective materials for the prevention and treatment of inflammatory diseases and in the areas of functional foods and cosmetics.

• Bulletin of the Korean Mathematical Society
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• v.58 no.1
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• pp.171-181
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• 2021

The fixing number of a graph G is the smallest order of a subset S of its vertex set V (G) such that the stabilizer of S in G, ��S(G) is trivial. Let G1 and G2 be the disjoint copies of a graph G, and let g : V (G1) → V (G2) be a function. A functigraph FG consists of the vertex set V (G1) ∪ V (G2) and the edge set E(G1) ∪ E(G2) ∪ {uv : v = g(u)}. In this paper, we study the behavior of fixing number in passing from G to FG and find its sharp lower and upper bounds. We also study the fixing number of functigraphs of some well known families of graphs like complete graphs, trees and join graphs.

• Current Research on Agriculture and Life Sciences
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• v.4
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• pp.127-131
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• 1986

In order to know the effects of iron the lipid characteristics in common feed, vitamin E and free unsaturated fatty acid concentrations were determined using feeds with(uncommon) and without(common) water added. The vitamin E concentrations in common feed(P<.05) and uncommon one (P<.01) showed statistically continuous decreasing figure from 1.75mg/g(1 day) to 0.25mg/g(11 days). The free unsaturated fatty acid concentrations in common feed showed also statistically continuous decreasing figure from 23.8mg/g(control group) to 17.6mg/g(20% ferrous sulfate group) (p<.01). On the mean time, quantitative values in uncommon feed have shown statistically continuous decreasing figure from 23.9mg/g(control group) to 17.4mg/g(20% ferrous sulfate group) (P<.01). The concentrations of vitamin E and free unsaturated fatty acid in common feed was higher than those in uncommon one, but significant difference was not recognized. The interactions between time lapse and ferrous sulfate were recognized in respect to the vitamin E and free unsaturated fatty acid in common and uncommon feed.

• Journal of The Korean Astronomical Society
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• v.44 no.5
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• pp.195-200
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• 2011

We have revisited the ACS Virgo Cluster Survey (ACSVCS), a Hubble Space Telescope program to obtain ACS/WFC g and z bands imaging for a sample of 100 early-type galaxies in the Virgo Cluster. In this study, we examine 51 nucleated early-type galaxies in the ACSVCS in order to look into the relationship between the photometric and structural properties of stellar nuclei and their host galaxies. We morphologically dissect galaxies into five classes. We note that (1) the stellar nuclei of dwarf early-type galaxies (dS0, dE, and dE,N) are generally fainter and bluer with g > 18.95 and (g-z) < 1.40 compared to some brighter and redder counterparts of the ellipticals (E) and lenticular galaxies (S0), (2) the g-band half-light radii of stellar nuclei of all dwarf early-type galaxies (dS0, dE, and dE,N) are smaller than 20 pc and their average is about 4 pc, and (3) the colors of red stellar nuclei with (g - z) > 1.40 in bright ellipticals and lenticular galaxies are bluer than their host galaxies colors. We also show that most of the unusually "red" stellar nuclei with (g-z) > 1.54 in the ACSVCS are the central parts of bright ellipticals and lenticular galaxies. Furthermore, we present multi photometric band color - color plots that can be used to break the age-metallicity degeneracy particularly by inclusion of the thermally pulsing-asymptotic giant branch (TP-AGB) phases of stellar evolution in the stellar population models.

• Korean Journal of Clinical Laboratory Science
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• v.56 no.2
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• pp.125-134
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• 2024

The present study was conducted to explore relationships between anemia and estimated glomerular filtration rate (eGFR) and urine microalbumin/creatinine ratio (uACR) in Korean adults with or without metabolic syndrome (MetS). The data of 4,943 adults aged ≥20 years who participated in KNHNES V-3 (2012) were analyzed. In the non-MetS group, the odds ratio (OR) for anemia of those with a decreased eGFR {eGFR<60 mL/min/1.73 m², 3.85 (95% confidence interval [CI], 2.03~7.30)} was significant as was the OR of those with decreased eGFR plus elevated uACR (eGFR<60 mL/min/1.73 m² and uACR≥30 mg/g, 5.81 [95% CI, 2.60~13.02]). In the MetS group, ORs for anemia for those with an elevated uACR (2.18 [95% CI, 1.11~4.27]), a decreased eGFR (3.74 [95% CI, 1.11~12.55]), or a decreased eGFR plus an elevated uACR (16.79 [95% CI, 5.93~47.57]) were significant. In conclusion, in non-MetS, anemia was associated with a low eGFR, whereas in MetS, anemia was associated with a low eGFR and an elevated uACR. In addition, the OR for anemia was greatly increased when eGFR was diminished and uACR was elevated regardless of MetS and MetS status.

• Korean Journal of Poultry Science
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• v.1 no.1
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• pp.5-11
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• 1973

1. 닭 우모색에 있어서 흑색 melanin이 착색을 이압하는 I gene은 8주시 체중을 억제하는 작용을 하였다. 2. Barring을 나타내는 B gene이 I gene과 E gene이 나타났을 때 8주시 체중을 더욱 억제하였다. 3. 확장 흑색인자인 E gene과 I gene이 상호작용을 할 때에 8주시 체중을 억제하나 I gene이 억제작용 하는 이상의 작용은 하지 않았다. 4. I gene의 성장률 억제작용은 8주시 체중이 900-1,100g였을 때 평균 암탉에 있어서 37g 수탉에 있어서 25g 수탉에 있어서는 40g이었다. 이 시기의 성장률에 대하여 I와 E B S.의 공동작용은 더욱 억제작용을 하였는데 890-1,070g시에 암탉에 있어서는 45g, 수탉에 있어서는 53g였다. (중략)

• Microbiology and Biotechnology Letters
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• v.36 no.4
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• pp.314-319
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• 2008

Penicillin G amidase (PGA, benzylpenicillinaminohydrolase, EC 3.5.1.11) is industrially important enzyme which converts penicillin G to 6-aminopenicillanic acid (6-APA) and phenylacetic acid (PAA). The PGA in E. coli ATCC 11105 is secreted into the periplasm after removing signal sequences and becomes heterodimer which composed of two subunits, small subunit (24 kDa) and large subunit (65 kDa). In this study, the PGA gene was obtained from E. coli ATCC 11105 using PCR (polymerase chain reaction) technique. The active PGA was successfully secreated into periplasm in E. coli BL2 1(DE3) harboring pET-pga plasmid. The optimized fed-batch fermentation, consisting of a three-step shift of culture temperature from $37^{\circ}C$ to $22^{\circ}C$, gave a productivity of 19.6 U/mL with a cell growth of 62 O.D. at 600 nm.

• Journal of Life Science
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• v.17 no.10
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• pp.1426-1433
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• 2007

To investigate the antibiotic resistant patterns of the bacteria producing ESBL, we isolated one organism of Klebsiella pneumoniae from a clinical laboratory in Busan. The organism that produces ESBL gene was detected by double disk synergy test and the presence of three ESBL genes (TEM-1, SHV-12, CTX-M-15) was confirmed by polymerase chain reaction and DNA sequencing analysis. To analyse the characteristics of three ESBL genes, we performed transconjugation, transformation and cloning experiment with the organism. The MIC of Klebsiella pneumoniae was revealed that ceftazidime, cefotaxime and ceftriaxone were $256\;{\mu}g/ml,\;128\;{\mu}g/ml\;and\;128\;{\mu}g/ml$ respectively. The MIC of conjugant (E. coli $RG176^{Na(r)}$) af was revealed that ceftazidime, cefotaxime and ceftriaxone were $256\;{\mu}g/ml,\;64\;{\mu}g/ml\;and\;128\;{\mu}g/ml$ respectively. The MIC of transformant (E. cofi $DH5{\alpha}$) was revealed that ceftazidime, cefotaxime and ceftriaxone were $128\;{\mu}g/ml,\;32\;{\mu}g/ml,\;and\;32\;{\mu}g/ml$ respectively, The MIC of cloned organism of SHV-12 gene (E. coli $DH5{\alpha}$) was revealed that ceftazidime, cefotaxime and ceftriaxone were $128\;{\mu}g/ml,\;8\;{\mu}g/ml,\;and\;32\;{\mu}g/ml$ respectively. The results indicated that MIC of conjugant was higher than MIC of transformant and also SHV-12 gene were not resistant against cefotaxime antibiotic.

• Journal of the Korean Wood Science and Technology
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• v.47 no.1
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• pp.40-50
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• 2019

The aim of this study was to investigate the effects of density, temperature, size, and grain direction on measurement of moisture contents (MC) of wood materials non-destructively. The MC of different sizes of solid wood, glulam, and CLT from larch (larix kaempferi, $560kg/m^3$) and pine (pinus koraiensis, $430kg/m^3$) were measured using the dielectric type and resistance type meters. The specimens were conditioned in the environmental chamber to be equilibrium moisture content (EMC) of 12 % and 19 %. When density setting in dielectric type meter was increased from $400kg/m^3$ to $600kg/m^3$, the MCs of specimen (S-L-100-E) were decreased from 13.4 % to 11.3 %. However, when wood group (WG) setting in resistance type meter was changed from WG1 to WG4, the measured MCs were increased from 9.2 % to 12.3 %. When temperature setting in resistance type meters was changed from 0 to $35^{\circ}C$, the MC was decreased from 17.0 % to 13.0 %. The MCs measured by dielectric type meter for larger specimens (S-L-100-E_11.3 %, G-L-240-E_11.7 % and C-L-120-E_12.8 %) were higher than those of small size specimens (S-L-30-E_8.7 %, G-L-150-E_10.3 %, and C-L-90-E_9.7 %). The MCs measured by resistance type meter for larger specimens (G-L-240-E_11.6 % and C-L-120-E_13.3 %) were also higher than those of small size specimens (G-L-150-E_10.4 %, and C-L-90-E_11.8 %). The resistance type meter was not affected by the grain direction but the dielectric type meter were affected by the grain direction. The MC measured by resistance type meter for G-L-120-E perpendicular to grain direction was 11.5 % and the measured MC parallel to grain direction was 11.3 %. The MC measured by dielectric type meter parallel to grain direction (12.1 %) was higher than that measured perpendicular to grain direction (10.7 %).

• Microbiology and Biotechnology Letters
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• v.16 no.2
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• pp.111-118
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• 1988

The growth inhibition of enteropathogenic Escheriohia coli $A_2$and Escherichia coli G$_7$, causing the diarrhea in piglets, by the organic acid producing bacteria was studied in vitro. The metabolites of the organic acid bacteria, such as lactic acid, acetic acid inhibited the growth of E. coli $A_2$and E. coli G$_7$ in BL medium. The more the organic acid producing bacteria have ability to produce the organic acids, the higher these bacteria excelled the inhibitory efficacy against enteropathogenic E. coli. Among the strains examined, Lactobacillus casei Y and Streptococcus faecium C showed relatively strong growth inhibition against enteropathogenic E. coli.. When the organic acid producing bacteria and the enteropathogenic E. coli were incubated simultaneously in BL medium, bacteriostasis of E. coli was observed when the pH of BL culture was lowered to 5.0, and bacteriocidal effect was observed when the pH became Bess than 4.5, E. coli. $A_2$was more resistant to the organic acid bacteria than E. coli G$_7$.