• The KIPS Transactions:PartA
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• v.14A no.3 s.107
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• pp.147-150
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• 2007

This paper describes a new low-swing inverter for low power consumption. To reduce a power consumption, an output voltage swing is in the range from 0 to VDD-2VTH. This can be done by the inverter structure that allow a full swing or a swing on its input terminal without leakage current. Using this low-swing voltage technology, we proposed a low-power 16$\times$16 bit parallel multiplier. The proposed circuits are designed with Samsung 0.35$\mu$m standard CMOS process at a 3.3V supply voltage. The validity and effectiveness are verified through the HSPICE simulation.. Compared to the previous works, this circuit can reduce the power consumption rate of 17.3% and the power-delay product of 16.5%.

• Cross-Cultural Studies
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• v.39
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• pp.97-125
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• 2015

Significance of the R16 Korea Contest as Culture Contents. Known for relentless practice and intense moves, widespread presence on the Internet, strong ethnic elements highlighting Korean physical attributes and collective culture, b-boying occupies a special place in Korea today. News of four consecutive wins in major b-boy contests around the world have changed the common public conception that b-boys are simply a group of problem boys and students in hip-hop clothes intent on showing off their dance moves. B-boying is no longer perceived as a dance that is performed in the shadowy underground but as a dynamic and beautiful art form of physical expression that is part of today's popular culture. This paper examines the significance of R-16 Korea as culture contents and its main event, the World B-boy Masters Championship. It introduces how the contest has developed since 2007 to reach popular influence and gain international recognition. The paper also compares R-16 Korea to the world's four major b-boy contests, Battle Of The Year, UK B-boy Championship, Free Style Session, and Red Bull BC One to see if any distinctions could be found among them and to evaluate the significance of R-16 Korea as cultural content in its rise to one of the world's top 5 major b-boy contests. Finally, this study makes suggestions for b-boying to become more established as part of Korea's culture contents.

• Proceedings of the Korean Society of Broadcast Engineers Conference
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• 2018.11a
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• pp.15-17
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• 2018

VVC(Versatile Video Coding)는 입력된 영상을 CTU(Coding Tree Unit) 단위로 분할하여 코딩하며, 이를 다시 QTBTT(Quadtree plus binary tree and triple tree)로 분할하고, TU(Transform Unit)도 이와 같은 단위로 분할된다. 따라서 TU의 크기는 $4{\times}4$, $4{\times}8$, $4{\times}16$, $4{\times}32$, $8{\times}4$, $16{\times}4$, $32{\times}4$, $8{\times}8$, $8{\times}16$, $8{\times}32$, $16{\times}8$, $32{\times}8$, $16{\times}16$, $16{\times}32$, $32{\times}16$, $32{\times}32$, $64{\times}64$의 17가지 종류가 있다. 기존의 VVC 참조 Software인 VTM에서는 디블록킹필터와 SAO(Sample Adaptive Offset)로 이루어진 인루프필터를 이용하여 에러를 복원하는데, 본 논문은 TU 크기에 따라서 원본블록과 복원블록의 차이(에러)가 통계적으로 다름을 이용하여 서로 다른 CNN(Convolution Neural Network)을 구축하고 에러를 복원하는 방법으로 VTM의 인루프 필터를 대체한다. 복원영상의 에러를 감소시키기 위하여 TU 블록크기에 따라 DenseNet의 Dense Block기반 CNN을 구성하고, Hyper Parameter와 복잡도의 감소를 위해 네트워크 간에 일부 가중치를 공유하는 모양의 Network를 구성하였다.

• Journal of Broadcast Engineering
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• v.28 no.1
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• pp.21-30
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• 2023

Computer-generated holography requires much more computation costs and memory space rather than image processing. We implemented the diffraction calculation with low-precision and mixed-precision floating point numbers and compared the processing time and quality of the hologram with various precision. We compared diffraction quality with double, single and bfloat16 precision. bfloat16 shows 5.94x and 1.52x times faster performance than double precision and single precision. Also, bfloat16 shows lower PSNR and SSIM and higher MSE than other precision. However, there is no significant effect on reconstructed images. These results show low precision, like bfloat16, can be utilized for computer-generated holography.

• Journal of Physiology & Pathology in Korean Medicine
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• v.23 no.1
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• pp.63-75
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• 2009

The aim of this study was to elucidate the antimelanogenic effect of Dokhwalkisaeng-tang(Duohujisheng-tang) in B16F10 melanoma cells. Dokhwalkisaeng-tang(DKT) was used to develop the effective prescription of inhibition of melanin production. We determined inhibitory effects of DKT on melanin-release, melanin production, and tyrosinase activity in B16F10 melanoma cells. And to explicate the action-mechanism of DKT, melanin-related gene expressions were determined using RT-PCR and real time RT PCR technique in B16F10 melanoma cells. DKT inhibited melanin-release, melanin production in B16F10 melanoma cells considerably. DKT inhibited tyrosinase activity in vitro and in B16F10 melanoma cells. DKT inhibited the expression of tyrosinase, TRP-1, TRP-2 in B16F10 melanoma cells. DKT inhibited the expression of PKA, PKC, MMP-2 and MITF in B16F10 melanoma cells. On the other hand, DKT increased the expression of ERK-1, ERK-2, AKT-1 in B16F10 melanoma cells. From these results, we propose that DKT may have effect on the antimelanogenesis.

• Proceedings of the Korean Radioactive Waste Society Conference
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• 2004.06a
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• pp.261-267
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• 2004

Inventories, projections, and characteristics of spent nuclear fuel(SNF) generated from domestic nuclear power plants were updated to support high-level waste disposal system design. The historical and projected inventory by the end 2055 is expected to be 20,500 and 14,800MTU for PWR and CANDU spent nuclear fuel, respectively The ratio of quantity for TEX>$17{\times}17$ SNF was shown to be 0.6 as of 2003. The amount of TEX>$17{\times}17$ SNF, however, will be less than that of TEX>$16{\times}16$ KSFA after 2012, while the quantity of TEX>$16{\times}16$ KSFA will reach to 70% of the total spent fuels in the 2055. Average turnup of SNF revealed ~36GWD/MTU and ~40GWD/MTU for the period of 1994-1999 and 2000-2003, respectively. It is expected that the average burnup of SNF will exceed 45GWD/MTU at the end of 2000's. Therefore, it seems reasonable to use the TEX>$17{\times}17$ 4.5w/o, 45GWD/MTU as the Reference SNF at present state. The TEX>$16{\times}16$ KSFA 4.5w/o, 55GWD/MTU, however, should be Reference SNF after ~2010.

• Journal of Microbiology
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• v.40 no.4
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• pp.313-318
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• 2002

To perform the prophylactic study of a vaccine derived from human papillomavirus (HPV) using Balb/c mice, we produced virus like particles consisting of HPV capsid protein L1 which has been reported to induce significant humoral and cellular immunity using various animal model systems. In order to produce HPV16 VLPs, the cDNA of L1 capsid protein in HPV type 16, obtained by polymerase chain reaction, was inserted into yeast expression vector, YEG$\alpha$-HIR525 under the control of GAL10 promoter. The transformation of YEG$\alpha$-HPV16 L1 was performed into the yeast Saccharomyces cerevisiae Y2805 by the lithium acetate method and the yeast clone expressing the highest level of L1 capsid protein of human papillomavirus type 16 was selected by Western blot analysis using anti-HPV16 L1 antibody. The purification of HPV16 VLP has been performed by the ultracentrifugation and gel-filtration methods. To validate the vaccine efficacy of the purified HPV16 VLPs and investigate the properties of HPV16 VLPs to induce humoral immunity, ELISA assay was performed. A significantly increased production of anti-HPV16 VLP antibodies was observed in sera from immunized mice. The neutralization activity of antibodies in the sera from the vaccinated mice was demonstrated by a rapid and simple assay to detect hemagglutihation inhibition activity.

• The Plant Pathology Journal
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• v.36 no.5
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• pp.459-467
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• 2020

Areca palm yellow leaf (AYL) disease caused by the 16SrI group phytoplasma is a serious threat to the development of the Areca palm industry in China. The 16S rRNA gene sequence was utilized to establish a rapid and efficient detection system efficient for the 16SrI-B subgroup AYL phytoplasma in China by loop-mediated isothermal amplification (LAMP). The results showed that two sets of LAMP detection primers, 16SrDNA-2 and 16SrDNA-3, were efficient for 16SrI-B subgroup AYL phytoplasma in China, with positive results appearing under reaction conditions of 64℃ for 40 min. The lowest detection limit for the two LAMP detection assays was the same at 200 ag/μl, namely approximately 53 copies/μl of the target fragments. Phytoplasma was detected in all AYL disease samples from Baoting, Tunchang, and Wanning counties in Hainan province using the two sets of LAMP primers 16SrDNA-2 and 16SrDNA-3, whereas no phytoplasma was detected in the negative control. The LAMP method established in this study with comparatively high sensitivity and stability, provides reliable results that could be visually detected, making it suitable for application and research in rapid diagnosis of AYL disease, detection of seedlings with the pathogen and breeding of disease-resistant Areca palm varieties.

• Journal of Microbiology and Biotechnology
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• v.28 no.5
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• pp.776-783
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• 2018

The agarase gene gaa16a was identified from a draft genome sequence of Gilvimarinus agarilyticus JEA5, an agar-utilizing marine bacterium. Recently, three agarase-producing bacteria, G. chinensis, G. polysaccharolyticus, and G. agarilyticus, in the genus Gilvimarinus were reported. However, there have been no reports of the molecular characteristics and biochemical properties of these agarases. In this study, we analyzed the molecular characteristics and biochemical properties of agarases in Gilvimarinus. Gaa16A comprised a 1,323-bp open reading frame encoding 441 amino acids. The predicted molecular mass and isoelectric point were 49 kDa and 4.9, respectively. The amino acid sequence of Gaa16A showed features typical of glycosyl hydrolase family 16 (GH16) ${\beta}$-agarases, including a GH16 domain, carbohydrate-binding region (RICIN domain), and signal peptide. Recombinant Gaa16A (excluding the signal peptide and carbohydrate-binding region, rGaa16A) was expressed as a fused protein with maltose-binding protein at its N-terminus in Escherichia coli. rGaa16A had maximum activity at $55^{\circ}C$ and pH 7.0 and 103 U/mg of specific activity in the presence of 2.5 mM $CaCl_2$. The enzyme hydrolyzed agarose to yield neoagarotetraose as the main product. This enzyme may be useful for industrial production of functional neoagaro-oligosaccharides.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.6
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• pp.2869-2873
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• 2014

Background: Human papillomavirus (HPV) integration within the E2 gene has been proposed as a critical event in cervical carcinogenesis. This study concerned whether HPV16 status and E2 gene intactness are predictive of radiation response in patients with cervical cancer. Materials and Methods: Biopsies of 44 patients with cervical cancer were collected before or after radiotherapy. The presence of HPV16 was assessed by polymerase chain reaction (PCR) using specific primers for the L1 region. E2 disruption was detected by amplifying the entire E2 gene. Results: HPV16 DNA was found in 54.5% of the clinical samples. Overall, 62.5% of the HPV16 positive tumors had integrated viral genome and 37.5% had episomal genome. There was a tendency of increase of HPV16 E2 negative tumors compared with HPV16 L1 ones in advanced stages (75% versus 20% in stage III respectively). Detection of E2 gene appeared influenced by the radiotherapy treatment, as the percentage of samples containing an intact HPV16 E2 was more frequent in pretreated patients compared to radiotherapy treated patients (66.6% versus 20%). The radiation therapy caused an eight-fold [OR= 8; CI=1.22-52.25; p=0.03] increase in the risk of HPV16 genome disruption. The integration status is influenced by the irradiation modalities, interestingly E2 disruption being found widely after radiotherapy treatment (75%) with a total fractioned dose of 50Gy. Conclusions: This study reveals that the status of the viral DNA may be used as a marker to optimize the radiation treatment.