• Title/Summary/Keyword: 14-3-$3{\beta}$

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Analysis of Nursing Phenomena and Nursing Action using ICNP - Focused on orthopedic patients nursing records - (ICNP를 이용한 간호현상, 간호활동 분석 -정형외과 간호기록 중심으로-)

  • Ryu, Sun-Hee;Hong, Hae-Sook;Park, Sang-Youn;Lee, Eun-Joo
    • Journal of Korean Academic Society of Home Health Care Nursing
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    • v.11 no.1
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    • pp.14-22
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    • 2004
  • The purpose of this study was to establish the basic-data set for the electronic nursing records system by analysis of nursing phenomenas and nursing actions described in nursing records of orthopedic patients using the ICNP. Nursing notes for 1.421 days of 97 orthopedics patients who were discharged from a tertiary teaching hospital in Daegu were used. Narrative data from the nursing notes were collected. decomposed. and cross mapped with the concepts of the ICNP beta version. In total 11.442 statements were found in the process of decomposing the narrative data into single statement. These statements consist of 3.970(34.70%) nursing phenomena statements. 6.996(61.14%) nursing action statements, and 476(4.16%) other statements. Finally 312 unique statements were collected by integrating same or similar statements. These statements consist of 120 (38.46%) nursing phenomena statements. 154 (49.36%) nursing action statements. and 38 (12.18%) other statements. When this result was cross mapped with ICNP beta version. 77.0% of nursing statements were completely expressed. 17.0% of them were partially expressed. and 0.3% of them were not able to expressed at all. The findings of this study showed the usability of ICNP as terminology of electronic nursing records system. And the result of this study can be utilized for an ICNP-based electronic nursing records system and can help clinical nurses to spend more time on direct nursing.

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Nutritional Status, Nutrients Intakes, and Health Status of Young-old and Old-old Homebound Elderly in Korea (연소 · 고령 노인의 성별에 따른 건강 및 영양상태 비교 조사 연구)

  • Choi-Kwon, Smi;Choe, Myoung-Ae;Kim, Keum Soon;Yi, Myung Sun;Suh, Eunyoung;Suh, Minhee
    • Journal of Korean Biological Nursing Science
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    • v.14 no.3
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    • pp.183-192
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    • 2012
  • Purpose: Number of the old-old elderly is rapidly increasing in Korea, but it is unclear whether there are differences between old-old and young-old elderly in nutritional status, nutrient intakes and health status. The gender differences in Korean elderly in these conditions also remains unknown. This study, therefore, investigated gender-associated differences in nutritional, health status and nutrient intakes and how they are related among young-old and old-old homebound elderly. Methods: Two hundred and eighty elderly who were attending a local elderly welfare center were recruited. Evaluation included demographic, nutritional and health status related data, nutritional intakes, and life style related factors including physical activity. Results: Of the 280 subjects, old-old were 147 (52.5%) and young-old were 133 (47.5%). Male old-old elderly had more often abdominal obesity than female old-old, but male old-old more often had malnutrition than female old-old. There were few differences in nutrient intakes between old-old male elderly and female elderly after energy intakes were controlled. Male old-old more often had less intake of beta carotene and Vitamin A than female old-old. On the other hand, male old-old elderly more often had hypercholesterolemia and hypertension than male young-old. Conclusion: Male old-old may be at a greater health and nutritional risk than female old-old. Targeted nutritional intervention for male old-old emphasizing antioxidant nutritional intakes may be warranted.

Effects of 16-week Combined Exercise on Dementia, Depression, and Cognitive Function in Elderly Women (16주간의 복합운동이 고령여성의 치매관련인자, 우울감 및 인지기능에 미치는 영향)

  • Park, Chan-Ho;Cheon, Ji-Un
    • Journal of the Korean Applied Science and Technology
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    • v.36 no.2
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    • pp.456-467
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    • 2019
  • The purpose of this study was to investigate the effects of combined exercise on dementia, depression, and cognitive function in elderly women. This study subject were 28 elderly female volunteers, aged 76-83 years and they divided into the exercise group(n=14) and control group(n=14). The combined exercise included the elastic band exercise and aquarobics performed 3 times per week for 90 minutes during 16 weeks. The exercise intensity was set at RPE 10-11 for 1 week to 4 weeks, RPE 11-14 for 5 weeks to 16 weeks, respectively. The test data were analyzed by two-way repeated measures ANOVA, paired t-test, and independent t-test. The alpha level of .05 was set for all tests of significance. The findings of this study were as follows; ${\beta}-amyloid$ and depression were significantly decreased and DHEAs and cognitive function were significantly increased than control group. In conclusion, regular and continuous combined exercise was effective for improving dementia and had a positive effect on depression and cognitive function in elderly women.

Absence of Tocotrienol Form of Vitamin E in Purple Perilla (Perilla frutescens var. acuta Kudo) Seeds Confirmed by Comparative Analysis Using HPLC and GC (GC 및 HPLC 비교분석에 기초한 차조기 종실내 tocotrienol 부재의 평가)

  • Lee, Young-Sang;Kim, Min-Kyoung
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.53 no.spc
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    • pp.115-120
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    • 2008
  • Lipid soluble vitamin E consists of tocopherols and tocotrienols depending upon double bonds in phytyl side chains attached to chromanol ring. Recent reports on antioxidative, anticancer, and cholesterol-lowering effects of tocotrienols have increased researches and commercialization of tocotrienols. Purple perilla (Perilla frutescens var. acuta Kudo) has been reported as a plant containing tocotrienols along with tocopherol forms of vitamin E based upon normal phase HPLC analysis. To confirm the existence or absence of tocotrienol form of vitamin E in purple perilla, comparative analysis using HPLC, GC/FID, and GC/MSD has been conducted for 14 purple perilla genetic accessions collected from Korea and Japan. Normal phase HPLC analysis showed ${\alpha}-$, ${\beta}-$, ${\gamma}-$, and ${\delta}-tocopherols$ along with peaks with retention times quite similar to ${\beta}-$ and ${\gamma}-tocotrienols$. Same purple perilla samples, analysed by GC exhibited ${\alpha}-$, ${\beta}-$, ${\gamma}-$, and ${\delta}-tocopherols$ quantitatively equivalent to HPLC results. However, no peaks for ${\beta}-$ and ${\gamma}-tocotrienols$ could be observed and unknown two peaks of similar retention times with ${\beta}-$ and ${\gamma}-tocotrienols$ were identified not corresponding tocotrienols by GC/MSD. These results suggest the absence of tocotrienol form of vitamin E in purple perilla as well as the necessity of using GC-based qualitative and quantitative vitamin E analysis to avoid misinterpretation of peaks with similar retention times as tocotrienol isomers when analysed by an HPLC.

Effects of Health Behaviors, Premenstrual Coping and Premenstrual Syndrome Symptoms on Subjective Happiness in Female College Students (여대생의 건강행태, 월경전증후군 대처 및 증상이 주관적 행복감에 미치는 영향)

  • Kim, Ahrin;Jeon, Hae Ok;Chae, Myung-Ock
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.1
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    • pp.493-505
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    • 2017
  • This study examined the relationships between health behavior, premenstrual coping, premenstrual syndrome symptoms, and subjective happiness of female college students. The data were collected through self-report questionnaires between March 7 and April 20, 2016. Participants were comprised of a convenience sample of 122 female college students. Stepwise multiple regression analysis revealed subjective health status (${\beta}=.23$, p<.011), premenstrual syndrome symptoms (${\beta}=-.22$, p<.012), and average length of menstrual period (${\beta}=-.17$, p<.044) to be significant predictors of subjective happiness in female college students. These variables accounted for 14.0% of subjective happiness scores. It is meaningful that premenstrual syndrome symptoms and average length of menstrual period affected the subjective happiness in female college students. Therefore, to facilitate subjective happiness in female college students, efficient management and intervention regarding premenstrual syndrome symptoms and general health are required.

Mediating Effect of Career Preparation Behavior on Nursing Professionalism Related Factors of Nursing Students (간호대학생들의 간호전문직관 관련요인에서 진로준비행동의 매개효과)

  • Park, Hee-Sook;Choi, Dong-Sook;Kim, Hyo-Chun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.5
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    • pp.93-101
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    • 2019
  • This study was conducted to investigate the mediating effects of career preparation behavior on nursing professionalism related factors of nursing students. The subjects were 265 students in the first, second, third, and fourth grades of nursing schools in the Gyeongbuk area. Data were collected from May 7, 2018 to May 25, 2018 using structured questionnaires. Data were analyzed by t-tests, ANOVA, Pearson's correlation, and multiple regression analysis based on descriptive statistics (frequency, percentage, mean, standard deviation) using the SPSS 22.0 program. The results of this study showed that career identity and career attitude maturity have a partial mediation effect on career preparation behavior in relation to nursing professionalism. Career attitude maturity (${\beta}=.38$), career identity (${\beta}=.17$), and career preparation behavior (${\beta}=.14$) were significant factors affecting nursing professionalism and the explanatory power of these variables was 19%. Therefore, it is necessary to develop and apply educational methods to improve career preparation behaviors and enhance professionalism of nursing students. In addition, there is a need for follow-up research on the structural relationship between career preparation behaviors, which are concrete and practical actions related to nurse's careers, and how they affect other career-related variables.

Ursodeoxycholic Acid Ameliorates Pain Severity and Cartilage Degeneration in Monosodium Iodoacetate-Induced Osteoarthritis in Rats

  • Moon, Su-Jin;Jeong, Jeong-Hee;Jhun, Joo Yeon;Yang, Eun Ji;Min, Jun-Ki;Choi, Jong Young;Cho, Mi-La
    • IMMUNE NETWORK
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    • v.14 no.1
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    • pp.45-53
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    • 2014
  • Osteoarthritis (OA) is a degenerative joint disease characterized by a progressive loss of cartilage. And, increased oxidative stress plays a relevant role in the pathogenesis of OA. Ursodeoxycholic acid (UDCA) is a used drug for liver diseases known for its free radical-scavenging property. The objectives of this study were to investigate the in vivo effects of UDCA on pain severity and cartilage degeneration using an experimental OA model and to explore its mode of actions. OA was induced in rats by intra-articular injection of monosodium iodoacetate (MIA) to the knee. Oral administration UDCA was initiated on the day of MIA injection. Limb nociception was assessed by measuring the paw withdrawal latency and threshold. Samples were analyzed macroscopically and histologically. Immunohistochemistry was used to investigate the expression of interleukin-$1{\beta}$ (IL-$1{\beta}$), IL-6, nitrotyrosine and inducible nitric oxide synthase (iNOS) in knee joints. UDCA showed an antinociceptive property and attenuated cartilage degeneration. OA rats given oral UDCA significantly exhibited a decreased number of osteoclasts in subchondral bone legion compared with the vehicle-treated OA group. UDCA reduced the expression of IL-$1{\beta}$, IL-6, nitrotyrosine and iNOS in articular cartilage. UDCA treatment significantly attenuated the mRNA expression of matrix metalloproteinase-3 (MMP-3), -13, and ADAMTS5 in IL-$1{\beta}$-stimulated human OA chondrocytes. These results show the inhibitory effects of UDCA on pain production and cartilage degeneration in experimentally induced OA. The chondroprotective properties of UDCA were achieved by suppressing oxidative damage and inhibiting catabolic factors that are implicated in the pathogenesis of cartilage damage in OA.

Photochemical/Biophysical Properties of Proteorhodopsin and Anabaena Sensory Rhodopsin in Various Physical Environments (막 단백질인 Proteorhodopsin과 Anabaena Sensory Rhodopsin의 다양한 측정 환경에 따른 광화학/생물리학적 특성)

  • Choi, Ah-Reum;Han, Song-I;Chung, Young-Ho;Jung, Kwang-Hwan
    • Korean Journal of Microbiology
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    • v.47 no.1
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    • pp.22-29
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    • 2011
  • Rhodopsin is a membrane protein with seven transmembrane region which contains a retinal as its chromophore. Although there have been recently reports on various photo-biochemical features of rhodopsins by a wide range of purifying and measurement methods, there was no actual comparison related to the difference of biochemical characteristics according to their physical environment of rhodopsins. First, proteorhodopsin (PR) was found in marine proteobacteria whose function is known for pumping proton using light energy. Second one is Anabaena sensory rhodopsin (Nostoc sp.) PCC7120 (ASR) which belongs to eubacteria acts as sensory regulator since it is co-expressed with transducer 14 kDa in an operon. In this study, we applied two types of rhodopsins (PR and ASR) to various environmental conditions such as in Escherichia coli membranes, membrane in acrylamide gel, in DDM (n-dodecyl-${\beta}$-D-maltopyranoside), OG (octyl-${\beta}$-D-glucopyranoside), and reconstituted with DOPC (1,2-didecanoyl-sn-glycero-3-phosphocholine). According to the light-induced difference spectroscopy, rhodopsins in 0.02% DDM clearly showed photointermediates like M, and O states which respond to the different wavelengths, respectively and showed the best signal/noise ratio. The laser-induced difference spectra showed the fast formation and decay rate of photointermediates in the DDM solubilized samples than gel encapsulated rhodopsin. Each of rhodopsins seemed to be adapted to its surrounding environment.

Gas chromatographic profiles of rose essential oils: a round-robin test on oil of rose, Chinese Kushui type (Rosa sertata × Rosa rugosa) (장미 정유의 기체 크로마토그래피 분석표: 중국산 쿠스이형 장미유에 대한 재현정밀도 시험)

  • Son, Hyun-Hwa;Lee, Dong-Sun
    • Analytical Science and Technology
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    • v.25 no.4
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    • pp.207-213
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    • 2012
  • Analysis of the aroma constituents present in the rose essential oil of Chinese Kushui type (Rosa sertata ${\times}$ Rosa rugosa) by GC-FID and GC-MS was performed independently as an expert for the inter-laboratory round-robin test to verify reproducibility according to the decision of the preliminary meeting of ISO/TC-54 (Shanghai, Sep. 14-15, 2010). Total 179 peaks (using SPB-1 apolar column), 165 peaks (using DB-624 intermediate polar column), and 162 peaks (using Supelcowax-10 polar column) were separated by GC-FID, respectively. Major constituents (over 5%) by GC-FID were ${\beta}$-citronellol (41.6~46.7%), geraniol (9.7~11.0%), and nerol (3.4~4.5%). ${\beta}$-Citronellol peak was overlapped with nerol peak on SPB-1 and DB-624 columns, whereas the two peaks were separated each other on Supelcowax-10 column. Our results were generally consistent with Chinese data (ISO/DIS 25175); however, a peak of phenethyl alcohol separated by using PEG (Supelco wax) column was found at the quite different retention time. Comparative analysis was conducted using Bulgarian rose (Rosa damascena Miller) oil and perfume. Bulgarian rose oil showed rich amounts of characteristic aroma constituents than the essential oil of Chinese Kushui type.

Purification and Characterization of β-Lactamase Secreted from Bacillus sp. J105 Strain having β-Lectam Antibiotics Resistance. ((β-lactam계 항생물질 저항성을 지닌 Bacillus sp. J105 균주로부터 분비되는 베타 락탐 분해효소의 정제 및 특성)

  • Cho, Kyeong-Soon;Kang, Byoung-Won;Seo, Min-Jeong;Lee, Young-Choon;Lee, Jai-Heon;Joo, Woo-Hong;Choi, Yung-Hyun;Lim, Hak-Seob;Kim, Jeong-In;Seo, Kwon-Il;Jeong, Yong-Kee
    • Journal of Life Science
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    • v.18 no.6
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    • pp.845-851
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    • 2008
  • ${\beta}-Lactamase$, secreted from Bacillus sp. J105 strain was purified to a single band on SDS-PAGE by ammonium sulfate precipitation, ion exchange column chromatography and gel-filtration. The molecular weight of the purified enzyme was 31 kDa on SDS-PAGE and its isoelectric point was 7.35. Optimal pH and temperature for enzymatic reaction were 5 and $40^{\circ}C$, respectively. As a result of total amino acid composition analysis of the purified enzyme, Gly and Ala were occupied 14.1 and 13.3 mole %, respectively. Km and Vmax value of purified enzyme were 1.33 mM and 0.36 mM/ml using ampicillin as a substrate, respectively.