• Journal of Microbiology and Biotechnology
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• 제26권9호
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• pp.1533-1541
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• 2016

Samples of doenjang (a fermented soybean paste) were prepared with different types of salts; purified salt (PS), 3-year-aged solar salt (SS3), 1-year-aged solar salt (SS1), and bamboo salt (BS, 3^rd processing product). For starter doenjang samples, selected starters comprising two bacilli, one yeast, and one fungus were inoculated, whereas for non-starter doenjang samples, microorganisms present in rice straw were inoculated after enrichment. The doenjang samples were fermented for 13 weeks at 25℃. During the fermentation period, SS and BS doenjang samples showed higher bacilli counts as well as much lower yeast counts than PS doenjang. At 13 weeks, yeast counts of starter doenjang samples were 7.75, 5.69, 6.08, and 4.74 log CFU/g for PS, SS3, SS1, and BS doenjang, respectively. For non-starter doenjang samples, counts were 7.17, 5.05, 5.92, and 4.54 log CFU/g for PS, SS3, SS1, and BS doenjang, respectively. SS and BS promoted growth of bacilli but inhibited growth of yeasts compared with PS. Debaryomyces hansenii was the dominant yeast in PS doenjang, whereas Candida guilliermondii and Pichia sorbitophila were dominant in SS and BS doenjang. In the sensory evaluation, SS and BS doenjang scored better than PS doenjang. In conclusion, SS and BS seem better than PS for production of high-quality doenjang.

• Journal of Yeungnam Medical Science
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• 제40권1호
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• pp.49-57
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• 2023

Background: Several previous studies have reported that quality of life (QoL) in hemodialysis patients affects mortality. However, the 36-item Short Form Health Survey, which has been used mainly in previous studies, is complicated in terms of questionnaire composition and interpretation. This study aimed to identify the impact of QoL on mortality in hemodialysis patients using an easier and simpler diagnostic tool. Methods: This retrospective study included 160 hemodialysis patients. QoL was evaluated using the World Health Organization Quality of Life Questionnaire-Brief version (WHOQOL-BREF). Psychosocial factors were evaluated using the Hospital Anxiety and Depression Scale, Multidimensional Scale of Perceived Social Support, Montreal Cognitive Assessment, and Pittsburgh Sleep Quality Index. We also evaluated medical factors, such as dialysis adequacy and laboratory results. Results: The mean hemodialysis vintage was 70.7±38.0 months. The proportion of patients who were elderly was higher in the mortality group than in the surviving group, and the Charlson Comorbidity Index score was also higher in the former group. Of the four domains of the WHOQOL-BREF, the physical health and psychological scores of the mortality group were significantly lower than those of the survival group. When the score in the physical health domain or psychological domain was ≤10, the 10-year mortality rate after hemodialysis initiation increased by approximately 2.3- and 2-fold, respectively. Conclusion: QoL may have a significant effect on mortality in patients undergoing hemodialysis. The WHOQOL-BREF is an instrument that can measure QoL relatively easily and can be used to improve the long-term prognosis of patients undergoing hemodialysis.

• Journal of Gastric Cancer
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• 제7권4호
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• pp.219-227
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• 2007

목적: 위전절제술 후 이용될 수 있는 재건 술식에 대해서는 많은 방법들이 보고되어 왔지만 지금까지도 이상적인 술식에 대해서는 논쟁의 여지가 있고 장기간에 걸친 비교 연구는 더욱이 부족한 실정이다. 이에 저자는 본원에서 실시한 4가지 술식들인 Roux-en-Y 술식(R-Y), 공장간치술(JI), 공장낭간치술(JPI), Double-tract 재건술(DT)간의 경과 관찰을 통해 보다 나은 재건 술식을 찾고자 하였다. 대상 및 방법: 본원에서 2000년 8월부터 2004년 1월까지 위암으로 근치적 위전절제수술을 받고 재발이 없고 추적이 가능한 환자 중 80세 이상과 병기 IV기를 제외하고 재건 술식에 따라 RY군(n=15), JI군(n=8), JPI군(n=8), DT군(n=10)으로 분류한 총 41명의 환자를 대상으로 수술 후 증상, 수술 후 1년, 3년째의 혈액 및 생화학적 검사의 변화, 체중 변화를 포함한 영양학적 변화 및 삶의 질을 평가하기위한 GSRS score를 분석하였다. 또한 내시경 소견을 통해 위식도 역류 여부를 확인하였다. 결과: 검사실소견은 3년째 총단백과 알부민에서 DT군이 유의하게 낮은 결과를 보였고(P=0.006, P=0.033), 체중감소는 JI군이 1년, 3년째에서 수술 전 체중의 84.50%, 86.50%로 가장 많았다(P=0.013, P=0.011). GSRS score에서 JPI군이 수술 후 1년, 3년 모두에서 유의하게 더 좋은 결과를 보였다. (P=0.028, P=0.003). 결론: 공장낭간치술은 위전절제술 후 환자의 삶의 질을 높일 수 있는 유용한 재건 방식으로 생각된다.

• 성인간호학회지
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• 제14권1호
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• pp.15-25
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• 2002

Purpose: This study was performed to identify the prevalence and type of urinary incontinence (UI) after a stroke, to find the differences in urinary symptoms according to continence or incontinence, and to find the degree of impact of UI on daily life. Method: For data collection, we had a structured interview with a questionnaire. The subjects were 239 post stroke patients. Results: Among the subjects(mean age: $65{\pm}10$), 66.1 percent had an infarction, and 25.5 percent had a hemorrhage. And 26.4 percent of subjects were within 2 weeks and 28.9 percent from 1 year to 5 years since their episodes of a stroke. Forty five point six percent of subjects had various types of UI: urge 25.7 percent, stress 14.7 percent, functional 20.2 percent, and mixed 39.4 percent. There were significant differences in frequency, nocturia, decreased stream, and incomplete emptying between the incontinent and continent groups. Subjects reported UI influenced various aspect of daily life, 54.1 percent as cause of distress, 53.2 percent on overall quality of life, and 40.4 percent on sleep. The Mixed UI, including urge UI, had higher impact on daily life than others. Conclusion: There was a high prevalence of UI, mixed, urge, and functional type as most prevalent, and it had a strong impact on daily life of post stroke patients.

• 대한임상검사과학회지
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• 제38권2호
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• pp.141-146
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• 2006

Vagal nerve stimulation (VNS) has been proposed as a possible way to improve the control of refractory epilepsy. We report the effects following VNS treatment in patients with refractory epilepsy. Seventeen patients with a mean age of 12.8 years, ranging from 5 to 29 years, underwent the implantation of vagal nerve stimulation (Cyberonics, Houston, TX). We reviewed the clinical findings before and after VNS in seizure frequency, number of antiepileptic drugs (AED), and quality of life (QOL). All of the patients had intractable seizures, eleven of the patients had additional medical complications, three had hippocampus atrophy, one had encephalomalacia, five had encephalitis, one had pachygyria, and one had schizencephaly. Thirteen patients had symptomatic partial epilepsies, three patients had Lennox-Gastaut syndrome and one had cryptogenic partial epilepsy. The mean follow up duration was 35 months. The mean reduction of seizure frequency compared with baseline before VNS was 26.1% after 3 months (p<0.005), 41.9% after 6 months (p<0.001), 46.9% after 1 year (p<0.001), and 53% at the latest follow-up (p<0.001). Twelve patients showed an improvement of QOL such as mood, language, alertness, expression, and motor function. The most common side effects were transient hoarseness or voice change or cough, which was detected in six patients (35%) and wound infection in one patient (5%). This study has shown a good anti-seizure effect of VNS, decrease in seizure frequency and improvements in QOL. We concluded that VNS is a beneficial therapy in refractory epilepsy with a non-resectable epileptic focus. Further studies should be focused on the prediction of unresponsiveness and the adjustment of VNS parameters for maximum efficacy in patients with various medical histories.

• 대한한의학방제학회지
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• 제21권2호
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• pp.173-180
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• 2013

Objectives : A 55-year-old male patient whose symptoms were not improved by western drugs(including steroids) was hospitalized in Korean medical hospital for 22 days. Methods : This patient was diagnosed as Han-po-yeol(寒包熱) and treated with herbal decoctions, acupuncture, and moxibustion. And he answered the quality of life questionnaire for adult Korean asthmatics (QLQAKA) at 1st, 15th, and 22th day of hospitalization. Results : After 2 weeks herbal medical treatment, score of QLQAKA was increased by 0.53 point. Conclusion : This result suggest that Korean medical treatment has the potential for asthma patients who did not responded to western drugs.

• 지역사회간호학회지
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• 제23권4호
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• pp.438-445
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• 2012

Purpose: Medical Aid Beneficiaries were surveyed to identify differences in health behaviors, adherence to drug regimen, and quality of life between those people in the Designated Doctor System and those who are not. Methods: A total of 1,327 study subjects were separated into three groups: those in the Designated Doctor System for 2 years, those in for 1 year, and those not in the system. Results: After the introduction of the Designated Doctor System, 55.8% and 67.9%, respectively, of the subjects in the Designated Doctor System complained of inconvenience in relation to hospital use and the patient referral process. Also, the rate of emergency room use or hospitalization guided by the Designated Doctor System was only 8.7% and 6.5%, respectively. There were no significant differences in health behaviors and adherence to drug regimens between those in the Designated Doctor System and those who are not. Conclusion: This study was carried out early in the introduction of the system. Therefore, it is necessary to monitor the positive and negative effects of the Designated Doctor System for a full reflection of its impact.

• 한국사회정책
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• 제25권1호
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• pp.99-123
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• 2018

본 연구는 노인장기요양보험 인정자 중에서 사망한 자의 임종 관련 의료비를 분석함으로써, 향후 임종 관련 의료비의 효율적 관리방안과 양질의 임종관리 제공방안을 모색하는데 목적이 있다. 본 연구에서 활용한 자료는 건강보험 및 노인장기요양보험 급여이용자료, 통계청 사망원인 통계자료이며, 2008년 7월 1일부터 2012년 12월 31일까지 장기요양 인정등급을 받고 같은 기간 내 사망한 자 총 271,474명을 최종 분석대상자로 하였다. 연구결과 대상자는 여성(60.6%), 75세 이상(74.7%)이 다수를 차지했고, 대부분이 2개 이상의 질환을 보유하고 있었으며, 특히 고혈압(44.3%), 치매(42.3%), 뇌졸중(29.9%) 등 비율이 높았다. 사망원인은 순환기계질환(29.8%), 암(15.3%), 선천성 기형, 변형 및 염색체 이상(14.7%) 등의 순이었고, 사망장소로는 의료기관(64.4%), 자택(22.0%), 사회복지시설(9.2%) 순이었다. 대상자의 등급인정 이후 사망까지 소요시간은 평균 516.2일이었고, 대상자 중 99.3%는 사망 전 1년간 건강보험 또는 장기요양보험 급여를 이용하였다. 특히, 1인당 평균 총 급여비는 사망한 달에 가까워질수록 규모가 커져, 사망 전 12개월 보다 사망 전 1개월에 3배 이상 높아졌다. 또한, 사망 전 1개월간 대상자의 31.8%는 연명치료 범위에 해당하는 치료를 받은 것으로 나타났다. 향후 장기요양 인정자의 임종 관련 불필요한 의료이용 감소 및 효율적 의료관리를 위해 건강보험과 장기요양보험 급여의 통합적 임종관리 전달체계 확립과 호스피스 등 임종케어의 적극적 도입을 제안한다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권10호
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• pp.4451-4456
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• 2015

Background: The aim of our present study was to compare quality of life (QoL) between intermediate-stage (BCLC-B) HCC patients who had undergone either liver resection or transcatheter arterial chemoembolization (TACE). Materials and Methods: A total of 102 intermediate-stage HCC patients participated in our study, including 58 who had undergone liver resection and 44 who had undergone TACE. Baseline demographic characteristics, tumor characteristics, and long-term outcomes, such as tumor recurrence, were compared and analyzed. QoL was assessed using the Short Form (SF)-36 health survey questionnaire with the mental and physical component scales (SF-36 MCS and PCS). This questionnaire was filled out at HCC diagnosis and 1, 3, 6, 12, 24 months after surgery. Results: For the preoperative QoL evaluation, the 8 domains related to QoL were comparable between the two groups. The PCS and MCS scores were significantly decreased in both the TACE and resection groups at1 month after surgery, and this decrease was greater in the resection group. These scores were significantly lower in the resection group compared with the TACE group (P<0.05). However, these differences disappeared at 3 and 6 months following surgery. One year after surgery, the resection group showed much higher PCS scores than the TACE patients (P=0.018), and at 2 years after surgery, the PCS and MCS scores for the resection group were significantly higher than those for the TACE group (P<0.05). Eleven patients (19.0%) in the resection group and 17 (38.6%) in the TACE group suffered HCC recurrence (P<0.05). Univariate and multivariate analyses indicated that tumor recurrence (HR=1.211, 95%CI: 1.086-1.415, P=0.012) was a significant risk factor for poorpostoperative QoL in the HCC patients.Conclusions: Due to its effects on reducing HCC recurrence and improving long-term QoL, liver resection should be the first choice for the treatment of patients with intermediate-stage HCC.

• 농촌의학ㆍ지역보건
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• 제21권1호
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• pp.47-60
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• 1996

Home health care is one of the important components of health care services. Today, the need and demand for the home health care is increasing. To assess the effects of home visit health services by public health nurses in health center on the stat of health, use of medical services and quality of life by elderly people living at home, a randomized controlled trial was implemented for 65 years or more old people randomly allocated to intervention(93) and control(118) group. Intervention group received 2 visits a month over 6 months. Control group received no home visits. The data was collected in a one-year follow-up survey conducted at Kyongju before and after the intervention which composed of health risk assessment, risk factor education and health related behavior counseling. The prevalence rate of chronic illness was more decreased in intervention group than control group after intervention. The intervention group visited medical facilities less frequently than control group. And the home visit health services encouraged the elderly to practice regular exercise. After the intervention, the score of ADL(activities of daily living), LSI(life satisfaction index) and SSI(social support index) in intervention group were more increased than control group. And the increase of scores was more prominent in 70 years or more old people, female, non-smoker and non-chronic illed elderly rather than others. In conclusion, the regular home visit health services provided by public health nurses were beneficial for the elderly in terms of health promotion and quality of life.