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Identification of Reassortant Pandemic H1N1 Influenza Virus in Korean Pigs

  • Han, Jae-Yeon;Park, Sung-Jun;Kim, Hye-Kwon;Rho, Se-Mi;Nguyen, Giap Van;Song, Dae-Sub;Kang, Bo-Kyu;Moon, Hyung-Jun;Yeom, Min-Joo;Park, Bong-Kyun
    • Journal of Microbiology and Biotechnology
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    • v.22 no.5
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    • pp.699-707
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    • 2012
  • Since the 2009 pandemic human H1N1 influenza A virus emerged in April 2009, novel reassortant strains have been identified throughout the world. This paper describes the detection and isolation of reassortant strains associated with human pandemic influenza H1N1 and swine influenza H1N2 (SIV) viruses in swine populations in South Korea. Two influenza H1N2 reassortants were detected, and subtyped by PCR. The strains were isolated using Madin-Darby canine kidney (MDCK) cells, and genetically characterized by phylogenetic analysis for genetic diversity. They consisted of human, avian, and swine virus genes that were originated from the 2009 pandemic H1N1 virus and a neuraminidase (NA) gene from H1N2 SIV previously isolated in North America. This identification of reassortment events in swine farms raises concern that reassortant strains may continuously circulate within swine populations, calling for the further study and surveillance of pandemic H1N1 among swine.

Contribution analysis of Hanwoo carcass traits on unit price in national slaughter house

  • Eum, Seung-Hoon;Park, Hu-Rak;Seo, Jakyeom;Cho, Seong-Keun;Kim, Byeong-Woo
    • Korean Journal of Agricultural Science
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    • v.43 no.4
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    • pp.603-611
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    • 2016
  • The aim of this study was to analyze the contribution factors (backfat thickness, eye muscle area, carcass weight, marbling score, and feeding period) affecting meat unit price (South-Korean Won / Kg of meat). The best slaughtering age to maximize unit price was also assumed. All data used in this study were acquired from the Korea Institute for Animal Products Quality Evaluation from 2010 to 2014. Contributions to the estimated unit price of cows by the following factors, backfat thickness, eye muscle area, carcass weights, feeding period, and marbling score were 2.65%, 0.04%, 1.58%, 1.58%, and 95.72%, respectively. Contribution to estimated unit price of steers by the same factors (backfat thickness, eye muscle area, carcass weights, feeding period, and marbling score) were 7.88%, 1.24%, 0.07%, 90.81%, and 95.72%, respectively. Slaughtering ages ranged from 26 to 36 months and the data were separated into each month for an 11 month period. The unit price of meat from Hanwoo slaughtered at 30 months was highest among groups. The lowest unit price was observed in the group belonging to the Hanwoo slaughtered at 36 months. In conclusion, of all contributing factors, marbling score affected unit price the most. Based on our results, it is recommended that the optimal slaughtering age be set at 30 months to maximize unit price. Moreover, the feeding of beef cattle past 30 months of age is not recommended because of the increase in feeding costs.

ON CONTACT THREE CR SUBMANIFOLDS OF A (4m + 3)-DIMENSIONAL UNIT SPHERE

  • Kwon, Jung-Hwan;Pak, Jin--Suk
    • Communications of the Korean Mathematical Society
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    • v.13 no.3
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    • pp.561-577
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    • 1998
  • We study (n+3)-dimensional contact three CR submanifolds of a Riemannian manifold with Sasakian three structure and investigate some characterizations of $S^{4r+3}$(a) $\times$ $S^{4s+3}$(b) ($a^2$$b^2$=1, 4(r + s) = n - 3) as a contact three CR sub manifold of a (4m+3)-dimensional unit sphere.

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Radioopacity of Absorbable Plate containing Hydroxyapatite and Gold(Au); A Preliminary Report (Hydroxyapatite와 금(Au)이 혼합된 흡수성 고정판의 방사선비투과성; 예비 실험)

  • Kim, Yong Ha;Nam, Hyun Jae;Lee, Joon Ho;Kim, Kap Joong;Kim, Yeon Jung;Choi, Sik Young
    • Archives of Plastic Surgery
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    • v.35 no.4
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    • pp.419-422
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    • 2008
  • Purpose: Absorbable bone fixation materials for operation of facial bone fracture are composed of poly- lactic acid(PLA) & poly-glycolic acid(PGA). These materials are absorbed after facial bone healing period. Therefore, these materials are harmless in human body. But because of it's radioopacity, the number and the location of the materials are not checked in follow-up X-ray examination. We studied absorbable bone fixation materials checked radiological examination. So, we made the absorbable plate composed of PLA, Hydroxyapatite (HA) and Gold(Au). Methods: Plate 1 was consisted of pure PLA. Plate 2 was consisted of PLA(50%) and HA(50%). Plate 3 - 7 were consisted of PLA(50%), and variable composition of HA & Au. The ratio of Au was as following. From the plate 3 to plate 7, the Au ratio was 1%, 5%, 10%, 17%, and 25%, respectively. Total 3 examinations were used-naked eye examination, simple X-ray examination, and Haunsfield unit of plate in CT examination. Results: Naked eye examination found out that the color of plate 1 was most white. As the Au ratio increases, the color of plate was getting close to khaki color. the radioopacity of plate 2 was similar cortical bone of face in simple X-ray. The Haunsfield unit of cortical bone of face was 1000 HU. Haunsfield unit of titanium plate was 2900 HU. Haunsfield unit of plate 1 through plate 7 were -242, 1489, 1776, 3052, 3092, 3095, and 3095, respectively. Conclusion: Radioopacity of plate 2 was similar to cortical bone of face. In CT examination, Hanusfield unit of plate 2 was similar to Hanusfield unit of cortical bone of face. Hanusfield unit of plate 4 - 7 were similar to Hanusfield unit of titanium plate. So to trace bone fixation materials after facial bone surgery, the best ratio of Au is about 1 - 5%. If this study is applied to facial bone surgery, radiologic follow up would be easy after facial bone surgery.

HVAC & Refrigeration System for Work Barge Vessel (WORK BARGE 선의 냉동.공조 SYSTEM)

  • Nam, Im-Woo;Jung, Jae-Chun;Kim, Bong-Je
    • Proceedings of the SAREK Conference
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    • 2008.06a
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    • pp.583-590
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    • 2008
  • 최근 작업자 숙소 및 이송용 외에 작업용으로 사용 가능한 Barge선의 일종인 Accommodation Work Barge 선의 건조량이 증가 추세인 바 현재 중국에서 건조 중인 해당 선박의 HVAC & Refrigeration system에 대하여 정리하였다. 본 시스템은 R404A Direct expansion 냉각방식 (직접팽창방식)이 적용되었으며 HVAC system 중 Air conditioning 부분에 대해서는 선박의 각 Deck 기준으로 Zoning 하여 개별적인 Air handling unit와 Condensing unit를 구성하였으며 (각 unit의 용량은 필요용량의 100%), 냉동 창고의 Refrigeration system은 해당 격실 (육고, 어고, 야채고)에 각각 Unit cooler를 설치하고, Condensing unit를 기계실에 설치하였다. 장비는 전체 용량 100%에 대하여 항시 운전하는 100% 용량의 장비와 비상시에 운전하는 100% 용량의 예비 장비로 구성된다. 냉동 창고에 인접한 Dry provision store는 냉동 창고와는 별개로 중앙 공조기로부터의 냉각 공기를 이용하여 Spot cooling하였다. 본 System의 구성에 대한 장점 및 단점은 아래와 같다. 1. Air conditioning system이 각 Zone에 대하여 구성되므로 각 Zone에 대하여 제어가 가능하다. 2. Air con. 실에 Air handling unit와 Condensing unit가 설치되므로 냉매 배관의 길이가 짧다. 3. Air con. 실에 Air handling unit와 Condensing unit가 설치되므로 실내의 Maintenance space 상에 여유가 없다.

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Analysis of rainfall infiltration characteristics for unsaturated soils using a column test equipment (모형실험장치를 이용한 불포화토의 강우 침투특성 분석)

  • Park, Kyu-Bo;Chae, Byung-Gon;Kim, Kyeong-Su
    • Proceedings of the Korean Geotechical Society Conference
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    • 2010.09a
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    • pp.736-742
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    • 2010
  • This study was conducted to characterize on the relationships of rainfall intensity and infiltration rate of rainfall dependent on unit weight change in the gneissic weathered soil by a column test equipment. In this study, volumetric water content and pore water pressure were measured using TDR sensors and tensiometers at regular time intervals. Rainfall conditions including continuous rainfall and repeated rainfall were selected in order to know the effect of antecedent rainfall. In the condition of rainfall intensity 20mm/h and the unit weights of soil as $1.35g/cm^3$, $1.55g/cm^3$ and $1.61g/cm^3$, average rainfall infiltration rate was $2.814{\times}10^{-3}cm/sec$, $1.969{\times}10^{-3}cm/sec$ and $1.252{\times}10^{-3}cm/sec$ respectively. The higher rainfall intensity and lower unit weight of soil, the faster average infiltration rate. Overflow in the column was happened except rainfall condition of rainfall intensity 20mm and soil unit weight $1.35g/cm^3$. Increasing the soil unit weight, overflowed water was increased and occurrence time was faster.

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Optical system design for laser scanning unit (Laser Scanning Unit용 광학계 설계)

  • 임천석
    • Korean Journal of Optics and Photonics
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    • v.10 no.1
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    • pp.15-20
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    • 1999
  • Laser Scanning Unit (LSU), which is one of the core parts of laser printer, consists of LD Module, cylinder lens, polygon mirror and f$\theta$ lens. After making an initial design on each part, we optimized the one which satisfies the user specification. The optimized optical system has diffraction limited performance for the slit size of 2.7 mm$\times$1.6 mm, f$\theta$ characteristics less than 0.3% and field curvature less 1.2 mm. We also calcurate tolerance of each part based on RSS(Root Sum Square) method to manufacture LSU for mass production.

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A Basic Study of the Planning of the Housing Unit for Three Generation Family (3세대 가족형 공동주택의 계획에 관한 기초연구)

  • 민경애
    • Journal of the Korean Home Economics Association
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    • v.25 no.1
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    • pp.83-92
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    • 1987
  • Information on the planning of the housing unit for three generation family is required for developing nuclear families and increasing elderly person. This study deal with the life style, it's characteristics and housing needs of the elderly who lived with other two generations. Specifically, this study attempted to find the basic information of the detailed planning and the establishment of criteria of the housing unit for three generation family. The results of this study were as follows. 1. Planning of the housng unit for three generation family, it had to be taken over residency areas for elderly especially for keeping privacy each other. 2. It was necessary the criteria of housing standards for eldery based on their housing characteristics. 3. Considering the psychological characterstics and life style of the elderly, it should be suggest that they could live easily with their next generation in the samecommunity. Also, the public policy should take over the housing unit for three generation family.

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A Study of Estimation of Carbon Effects per Unit Area by Park & Green Type in Development Project Area (개발사업지구의 공원 · 녹지 유형별 탄소효과 원단위 산정에 관한 기초연구)

  • Kang, Myung-Soo;Kim, Jong-Rim;Kim, Nam-Jung
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.16 no.5
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    • pp.71-81
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    • 2013
  • This study is aimed to provide basic data for the estimation of carbon effects in development project areas such as Happy Housing Project which includes redevelopment and reconstruction projects by inducing the basic unit of carbon effects and strategic planning and management to enhance carbon effects. According to the analysis, in urban parks, carbon uptake and carbon storage by the unit area of living area parks were $7.614kg/m^2$ and $18.5203kg/m^2$ respectively while carbon uptake and carbon storage by the unit area of theme parks were $1.2261kg/m^2$ and $2.831kg/m^2$ each. In facility greens, carbon uptake and carbon storage were $0.5683kg/m^2$ and $0.6636kg/m^2$ respectively while they were $10.77kg/m^2$ and $13.69kg/m^2$ individually in other urban planning facilities. In other greens, on the contrary, carbon uptake and carbon storage were $0.45kg/m^2$ and $1.02kg/m^2$ respectively. In site landscape, carbon uptake and carbon storage by the unit area of apartment landscape were $3.7394kg/m^2$ and $9.2292kg/m^2$ each.

Effect of Ginsenoside Rc on the Pharmacokinetics of Mycophenolic Acid, a UGT1A9 Substrate, and its Glucuronide Metabolite in Rats

  • Park, So-Young;Jeon, Ji-Hyeon;Jang, Su-Nyeong;Song, Im-Sook;Liu, Kwang-Hyeon
    • Mass Spectrometry Letters
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    • v.12 no.2
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    • pp.53-58
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    • 2021
  • Previous in vitro studies have demonstrated that ginsenoside Rc inhibits UGT1A9, but there are no available data to indicate that ginsenoside Rc inhibits UGT1A9 in vivo. The effect of single and repeated intravenous injection of ginsenoside Rc was evaluated on the pharmacokinetics of mycophenolic acid. After injection of ginsenoside Rc (5 mg/kg for one day or 3 mg/kg for five days), 2-mg mycophenolic acid was intravenously injected, and the pharmacokinetics of mycophenolic acid and mycophenolic acid-β-glucuronide were determined. Concentrations of mycophenolic acid and its metabolite from rat plasma were analyzed using a liquid chromatography-triple quadrupole mass spectrometry. Single or repeated pretreatment with ginsenoside Rc had no significant effects on the pharmacokinetics of mycophenolic acid (P > 0.05): The mean difference in maximum plasma concentration (Cmax) and area under the concentration-time curve (AUCinf) were within 0.83- and 0.62-fold, respectively, compared with those in the absence of the ginsenoside Rc. These results indicate that ginsenoside Rc has a negligible effect on the disposition of mycophenolic acid in vivo despite in vitro findings indicating that ginsenoside Rc is a selective UGT1A9 inhibitor. As a result, ginsenoside Rc has little possibility of interacting with drugs that are metabolized by UGT1A9, including mycophenolic acid.