• Title/Summary/Keyword: 06A99

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Surgical Outcome of Patients with Ischemic Cardiomyopathy Selected by the Results of Myocardial Viability by Preoperative F-18 FDG PET (F-18 FDG 양전자단층촬영을 이용한 생존심근 평가 후 수술한 허혈성 심근병증 환자의 수술 결과)

  • Kim, Jae-Sung;Lee, Dong-Soo;Hong, Suk-Keun;Lee, Young-Tak;Kim, Yu-Kyeong;Kim, Youn-Jung;Moon, Keon-Sik;Won, Tae-Kyoung;Hwang, Hweung-Kon
    • The Korean Journal of Nuclear Medicine
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    • v.34 no.4
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    • pp.276-284
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    • 2000
  • Purpose: We investigated the operative outcome after bypass surgery in patients selected using viability criteria on F-18 FDG PET. Materials and Methods: Rest-24hr delay redistribution imaging of Tl-201 SPECT and F-18 FDG PET were performed in 11 patients. Seven of these 11 patients (6 men, 1 woman) were evaluated to have viable myocardium by F-18 FDG PET. Changes in symptoms and left ventricular ejection fraction (LVEF) after operation were evaluated. Results: In seven of 11 patients, a significant amount of viable myocardium was found on F-18 FDG PET and Tl-201 SPECT. Severity of both chest pain and dyspnea improved markedly in all patients. Mean LVEF improved from 22% to 32%. Conclusion: F-18 FDG PET could be used to select the patients who will benefit from coronary artery bypass surgery.

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Predictors of Outcome in Management of Paediatric Head Trauma in a Tertiary Healthcare Institution in North-Central Nigeria

  • Gyang Markus Bot; Danaan J. Shilong; Jerry A. Philip; Ezekiel Dido Dung; Andrew H. Shitta; Nanpan Isa Kyesmen;Jeneral D. Alfin; Lena Mary Houlihan; Mark C. Preul; Kenneth N. Ozoilo; Peter O. Binitie
    • Journal of Korean Neurosurgical Society
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    • v.66 no.5
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    • pp.582-590
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    • 2023
  • Objective : Trauma is a leading causes of death and disability in all ages. The aim of this study was to describe the demography and characteristics of paediatric head trauma in our institution and examine the predictors of outcome and incidence of injury related mortality. Methods : We examined our institutional Trauma Registry over a 2 year period. Results : A total of 1100 trauma patients were seen over the study period. Of the 579 patients who had head injury 99 were in the paediatric age group. Of the paediatric head trauma patients 79 had documented Glasgow coma score (GCS), 38 (48.1%), 17 (21.5%) and 24 (30.4%) had mild, moderate and severe head injury respectively. The percentage mortality of head injury in the paediatric age group was 6.06% (6/99). There is an association between mortality and GCS (p=0.008), necessity for intensive care unit (ICU) admission (p=0.0001), associated burns (p=0.0001) and complications such as aspiration pneumonia (p=0.0001). The significant predictors of outcome are aspiration (p=0.004), the need for ICU admission (p=0.0001) and associated burns (p=0.005) using logistic binary regression. During the study period 46 children underwent surgical intervention with extradural haematoma 16 (34.8%), depressed skull fracture 14 (30.4%) and chronic subdural haematoma five (10.9%) being the commonest indication for surgeries. Conclusion : Paediatric head injury accounted for 9.0% (99/1100) of all trauma admissions. Majority of patients had mild or moderate injuries. Burns, aspiration pneumonitis and the need for ICU admission were important predictors of outcome in children with traumatic brain injury.

Mechanical Properties of Precious Metal-Ceramic Alloy Joined by the Laser-Welding and the Soldering Method (레이저 용접과 납착법으로 연결된 귀금속성 금속-도재 합금의 물리적 성질)

  • Oh, Jung-Ran;Lee, Seok-Hyung;Woo, Yi-Hyung
    • Journal of Dental Rehabilitation and Applied Science
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    • v.19 no.4
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    • pp.269-279
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    • 2003
  • This study investigated the mechanical properties of precious metal-ceramic alloy joined by the laser-welding and the soldering compared with the parent metal. Twenty-four tensile specimens were cast in precious metal-ceramic alloy and divided into three groups of eight. All specimens in the control group(group 1) were left in the as-cast condition. Group 2 and 3 were the test specimens, which were sectioned at the center. Eight of sectioned specimens were joined by soldering with a propane-oxygen torch, and the remaining specimens were joined by laser-welding. After joining, each joint diameter was measured, and then tested to tensile failure on an Instron machine. Failure loads were recorded, and then fracture stress(ultimate tensile strength), 0.2% yield strength and % elongation calculated. These data for three groups were subjected to a one-way analysis of variance(ANOVA). Neuman-Keuls post hoc test was then used to determine any significant differences between groups. The fracture locations, fracture surfaces were examined by SEM(scanning electron microscope). The results were as follows: 1) The tensile strength and 0.2% yield strength of the soldered group($280.28{\pm}49.35MPa$, $160.24{\pm}26.67MPa$) were significantly less than both the as-cast group($410.99{\pm}13.07MPa$, $217.82{\pm}17.99MPa$) and the laser-welded group($383.56{\pm}59.08MPa$, $217.18{\pm}12.96MPa$). 2) The tensile strength and 0.2% yield strength of the laser-welded group were about each 98%, 99.7% of the as-cast group. There were no statistically significant differences in these two groups(p<0.05). 3) The percentage elongations of the soldered group($3.94{\pm}2.32%$) and the laser-welded group($5.06{\pm}1.08%$) were significantly less than the as-cast group($14.25{\pm}4.05%$) (p<0.05). 4) The fracture of the soldered specimens occurred in the solder material and many porosities were showed at the fracture site. 5) The fracture of the laser-welded specimens occurred also in the welding area, and lack of fusion and a large void was observed at the center of the fracture surface. However, the laser-welded specimens showed a ductile failure mode like the as- cast specimens. The results of this study indicated that the tensile strengths of the laser-welded joints were comparable to those of the as-cast joints and superior to those of the soldered joints.

TIMING AND SEQUENCE OF ERUPTION OF PERMANENT TEETH IN A SAMPLE OF CHILDREN FROM YONSEI DENIAL HOSPITAL (연세대학교 치과병원에 내원한 어린이에서의 영구치 맹출 시기 및 순서)

  • Kang, Tae-Sung;Choi, Byung-Jai;Kwon, Ho-Keun;Son, Heung-Kyu;Choi, Hyung-Jun
    • Journal of the korean academy of Pediatric Dentistry
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    • v.32 no.4
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    • pp.693-702
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    • 2005
  • Accurate timing and sequence of eruption of permanent teeth are indicies of growth and essential for pediatric dentistry and pediatric clinical orthodontics. From the children brought to the Yonsei Dental Hospital during 2001 to 2003, 654 boys and 542 girls, ranging in age from five to fourteen years, were selected and analysed. The following was concluded. 1. Eruption time of maxillary teeth is 6.81 years in boys, 6.78 years in girls for central incisor, 8.30 years in boys, 7.98 years in girls for lateral incisor, 10.28 years in boys, 10.04 years in girls for canine, 9.74 years in boys, 9.90 years in girls for first premolar, 10.87 years in boys, 10.41 years in girls for second premolar, 6.25 years in boys, 6.54 years in girls for first permanent molar, 12.21 years in boys, 12.03 years in girls for second permanent molar 2. Eruption time of mandibular teeth is 6.00 years in boys, 6.06 years in girls for central incisor, 6.99 years in boys, 6.74 years in girls for lateral incisor, 9.83 years in boys, 9.17 years in girls for canine, 9.92 years in boys, 9.75 years in girls for first premolar, 10.66 years in boys, 10.39 years in girls for second premolar, 5.99 years in boys, 5.75 years in girls for first permanent molar, 11.92 years in boys, 12.17 years in girls or second permanent molar. 3. The following eruption sequence was observed the first permanent molar erupted first, followed by the central incisor, the lateral incisor, the first premolar, the canine, the second premolar and the second permanent molar in the maxilla. The first permanent molar erupted first, followed by the central incisor, the lateral incisor, the canine, the first premolar, the second premolar and the second permanent molar in the mandible.

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Effects of ionizing and ultraviolet radiation on microbial mutation and DNA damage (전리방사선 및 자외선의 미생물 돌연변이와 DNA 손상에 대한 영향)

  • Nam, Ji-Hyun;Shin, Ji-Hye;Lee, Jung-Yun;Lee, Dong-Hun
    • Korean Journal of Microbiology
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    • v.53 no.1
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    • pp.20-28
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    • 2017
  • Physical sterilization methods using ultraviolet radiation and ionizing radiation such as gamma ray and electron beam are applied in various industry fields due to disinfection effects and economic efficiency but may also cause microbial mutation. In this research, Salmonella enterica and Escherichia coli strains were treated with ionizing and ultraviolet radiation and their survival rate, mutation rate, and DNA damage were studied to evaluate the genetic safety. The survival rate of the strains decreased drastically as the irradiation dose of ultraviolet ray, gamma ray, and electron beam increased, and over 90% of the strain was exterminated at a dosage of $0.40{\sim}25.06mJ/cm^3$, 0.11~0.22 kGy, 0.14~0.53 kGy respectively. In SOS / umu-test, genotoxicity causing DNA damage was identified in all samples. In Ames test, back-mutation rate increased to $3.82{\times}10^{-4}$ and $9.84{\times}10^{-6}$ respectively when exposed to ultraviolet ray and gamma ray. At exposure to ultraviolet ray, gamma ray, and electron beam with dosage of over 99.99% extinction rate of S. enterica TA100, back-mutation rate increased 347 times, 220 times, 0.6 times respectively to the spontaneous back-mutation rate. Rifampicin resistance mutation rate of E. coli CSH100 exposed to ultraviolet ray, gamma ray, and electron beam was $2.46{\times}10^{-6}$, $1.66{\times}10^{-6}$, $4.12{\times}10^{-7}$ respectively. Therefore, gamma radiation is effective in microorganism control from the perspective of disinfection and electron beam has the advantage of sterilizing with little DNA damage and bacterial mutation.

A Study on Social Efficacy of Senior Citizens in Welfare Centers in Some Areas according to Their Subjective Oral Health and Their Quality of Life related to Oral Health (일부지역 노인복지관 노인들의 주관적 구강건강상태에 따른 사회적 효능감 및 구강건강관련 삶의 질에 관한 연구)

  • Park, Hong-Ryurn;Ku, In-Young;Moon, Seon-Jeong
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.2
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    • pp.1000-1009
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    • 2014
  • This study selected 582 senior citizens who used 6 senior welfare centers in 7 districts, Daegu and analyzed questionnaires for them from January 9 through June 5, 2013 in order to look into their subjective oral health, social efficacy and quality of life according to their subjective cognition of oral health and their quality of life related to oral health according to sociodemographic characteristics and drew the following conclusions: Sex was statistically significant in toothache and xerostomia; age, in oral health, dysmasesis, toothache, periodontal complications and xerostomia; the level of education, in oral health, dysmasesis, toothache and periodontal complications; and the number of family members living together, in dysmasesis, toothache, periodontal complications, xerostomia and halitosis. Their responses to the question about their social efficacy according to oral health included: 'My oral health is not good' 3.11 points; and 'My jaw crackles or hurts' 1.99 points. In social efficacy according to their cognition of oral health, their health was 2.05 points while in the quality of life, their health was 3.41 points. In the scores of the quality of life related to oral health, for their health, functional limitation was 2.13 points; physical pain, 2.53; psychological discomfort, 2.17; physical limitation, 2.31; degradation of psychological ability, 2.06; degradation of social ability, 1.81; and social disadvantage, 1.99. In sum, it is judged that senior citizens' quality of life as well as their oral health will be enhanced when active seeking for plans to prevent the progress of oral diseases is sufficiently considered through continuously providing oral health education for the promotion of geriatric oral health and developing preventive programs.

Pharmacokinetics of cefadroxil after oral administration in olive flounder, Paralichthys olivaceus (Cefadroxil의 경구투여에 따른 넙치(Paralichthys olivaceus)에서의 약물동태학 연구)

  • Lee, Ji-Hoon;Park, Kwan Ha
    • Journal of fish pathology
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    • v.31 no.1
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    • pp.23-34
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    • 2018
  • The pharmacokinetic properties of cefadroxil (CDX) were studied after oral administration for 7 days to cultured olive flounders (average 660 g), Paralichthys olivaceus. For examination of pharmaco-kinetic profiles, CDX of 45 to 225 mg/kg body weight was administered at two different water temperatures, $13{\pm}3^{\circ}C$ or $22{\pm}3^{\circ}C$. CDX concentrations were determined in muscle, plasma, gastrointestinal tract, hematopoietic organs and liver by HPLC-MS/MS. Muscle samples were taken at 0.25, 0.5, 1, 3, 7, 14 and 28 days post dose, whereas plasma, gastrointestinal tract, hematopoietic organs and liver concentrations were measured at 1, 3, 7, 14 and 28 days post-dosing. The kinetic profiles of $C_{max}$, $T_{max}$, $T_{1/2}$ of CDX were analyzed by fitting to a non-compartmental model with PKSolver program. The following pharmacokinetic parameters were obtained with oral administration of 45 and 225 mg/kg at 13 and $22^{\circ}C$ in muscle, plasma, gastrointestinal tract, hematopoietic organs and liver, respectively: $C_{max}$ (maximum tissue concentration)=$985.98-5,032.86{\mu}g/kg$, $5,670.99-38,922.23{\mu}g/l$, $2,457.27-10,192.78{\mu}g/kg$, $886.04-3,070.87{\mu}g/kg$ and $1,188.15-3,814.33{\mu}g/kg$; $T_{max}$ (time for maximum concentration)= every 1 day; $MRT_{0-{\infty}}$ (mean residence time)= 1.51-4.74, 2.12-3.06, 4.25-13.18, 1.37-18.66 and 1.78-29.76 days; $T_{1/2}$ (half-life)= 1.08-3.47, 1.14-5.42, 3.56-10.99, 1.17-14.93 and 1.25-28.55 days.

Breast and Colorectal Cancer Screening and Associated Correlates among Chinese Older Women

  • Leung, Doris Y.P.;Leung, Angela Y.M.;Chi, Iris
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.1
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    • pp.283-287
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    • 2012
  • Objective: To explore the participation rates for breast and colorectal cancer screening and identify associated correlates among elderly women. Methods: Logistic regressions were conducted using data collected in 2006 from 1,533 elderly women aged 60 years or above who had completed a screening instrument, the Minimum Data Set-Home Care, while applying for long-term care services at the first time in Hong Kong. Results: The participation rates for breast and colorectal cancer screening among frail older Chinese women were 3.7% and 10.8% respectively. Cognitive status was inversely associated with the likelihood of participation in screening (breast: OR = 0.66, 95%CI = 0.47-0.94; colon: OR = 0.81, 95%CI = 0.66-0.99), as was educational level with the likelihood of participation in breast cancer screening (no formal education: OR = 0.20, 95%CI = 0.06-0.61, some primary education: OR = 0.31, 95%CI = 0.10-1.00). Conclusion: The delivery of cancer preventive health services to frail older women is less than ideal. Cognitive status and educational level were important factors in cancer screening behaviour. Tailor-made strategic promotion programmes targeting older women with low cognitive status and educational levels are needed to enhance awareness and acceptance within this vulnerable group.

Soft tissue changes in skeletal class II patients treated with bilateral sagittal split osteotomy advancement surgery (골격성 II 급 부정교합 환자의 하악골 전진술 후 연조직 변화 분석)

  • Shin, Hee-Jin;Kim, Jin-Wook;Park, Je-Uk
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.36 no.2
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    • pp.94-99
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    • 2010
  • The purpose of this study was to examine the soft tissue changes in skeletal class II patients after mandibular advancement by bilateral sagittal split ramus osteotomy (BSSRO). In Asian population, the incidence of skeletal class II malocclusion is lower than that of skeletal class III malocclusion unlike the caucasians. This study was conducted to figure out the ratio at which hard tissue and soft tissue changes after mandibular advancement by analyzing cephalograms of 13 patients that have undergone the mandibular advancement surgery. As a result, change ratios of Li, B', Pog' according to the movement of li, B, Pog were found to be 0.59, 1.06, 0.82. Also, vertical height of vermilion zone (Si-Vb) and lower lip and chin (Si-Me') were measured to evaluate vertical changes. Vermilion zone showed tendency to decrease by 1.02 mm on the average postoperatively, whereas vertical length of lower lip and chin showed tendency to increase by 3.57 mm on the average.

The Mediating Effects of Mothers' Management Strategies of Peer Relationship on the Relationship Between Maternal Beliefs on Social Development and Child's Peer Competence (어머니의 사회성 발달에 관한 신념이 유아의 또래유능성에 미치는 영향: 또래관계 관리전략의 매개효과를 중심으로)

  • Song, Ae-Ran;Ko, Young-Kwang;Um, Hee-Kyung;Song, Seung-Min
    • Korean Journal of Childcare and Education
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    • v.15 no.6
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    • pp.99-116
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    • 2019
  • Objective: This study examined the relationship between maternal beliefs on social development, management strategies of peer relations, and their child's peer competence in order to understand how to promote children's peer competence. Methods: Self-report questionnaires were used on 195 mothers with children four to years old. Data were analyzed using Pearson Correlation Analysis and Baron and Kenny's three-step regression. Results: First, there was a positive relationship between maternal beliefs on social development and their child's peer competence. Second, this study found that there were partial mediating effects of advice·support and supervision on the relationship between maternal beliefs on social development and children's social competence. Conclusion/Implications: The findings confirm that mothers' beliefs on social development and management strategies of peer relationships are proceeding factors for children's peer competence. Significant attention should be paid to mothers' beliefs on social development and management strategies of peer relationships for children's positive social development.