• Title/Summary/Keyword: 흑색종

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Bladder Cancer Metastasis to the Breast in a Male Patient: Imaging Findings on Mammography and Ultrasonography (남자 환자에서 방광암의 유방 전이암: 유방촬영술 및 초음파 영상 소견)

  • In Na Yoon;Eun Suk Cha;Jeoung Hyun Kim;Jee Eun Lee;Jin Chung
    • Journal of the Korean Society of Radiology
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    • v.83 no.3
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    • pp.687-692
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    • 2022
  • Male breast cancer is rare, accounting for approximately 1% of breast cancers. Metastasis from extra-mammary malignancy to the breast in men is extremely rare. The most common primary tumors that metastasize to the breast in male are prostate, lung, stomach, colorectal cancer, melanoma, and sarcoma. To our knowledge, only a few cases of bladder cancer presenting with metastasis to the male breast have been reported, and metastasis with infiltration rather than mass is extremely rare. We report imaging findings on mammography and ultrasonography in a 59-year-old male with bladder cancer metastatic to the breast.

Redescription of the Japanese blacktail triplefin, Springerichthys bapturus (Perciformes: Tripterygiidae), from Korea (한국산 청황베도라치 Springerichthys bapturus (농어목, 먹도라치과)의 재기재)

  • Kim, Byung-Jik;Endo, Hiromitsu;Lee, Young-Don
    • Korean Journal of Ichthyology
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    • v.17 no.2
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    • pp.148-151
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    • 2005
  • The Japanese blacktail triplefin, Springerichthys bapturus, is redescribed based on three specimens (36.6~55.4 mm SL) from Soheuksan and Jeju Islands. This is the first reliable record of the species from Korea. The specimens are characterized by having 26~28 second dorsal spines, 22~26 anal soft rays, 27~30 anterior lateral line scales, and intensive coloration of head and tail.

Development of Anticancer Agents from Korean Medicinal Plants (Part 8). - Cytotoxic Activity of Taraxaci Herba Extract against Human Skin Melanoma Cells - (한국산 생약으로부터 항암물질의 개발(제 8보) - 포공령 추출물이 인체 피부흑색종세포에 미치는 세포독성작용 -)

  • Oh, In-Kio;Yoo, Eun-Ah;Han, Du-Seok;Kang, Kil-Ung;Baek, Seung-Hwa
    • Korean Journal of Pharmacognosy
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    • v.29 no.3
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    • pp.198-203
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    • 1998
  • In the present study, we have evaluated cytotoxic effects of Taraxaci herba extract on human skin melanoma cells. The light microscopic study showed morphological changes of the treated cells. Disruptions in cell organelles were determined by calorimetric methods: MTT (3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazoliumbromide), NR (Neutral red) and SRB (Sulforhodamine B protein) assay. These results suggest that Taraxaci herba retains a potential antitumor activity.

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Record of a Juvenile Eyeshade Sculfin, Nautichthys pribilovius from Goseong, Korea (강원도 고성 연안에서 출현한 검은띠눈횟대 Nautichthys pribilovius의 유어)

  • Kim, Byung-Jik
    • Korean Journal of Ichthyology
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    • v.25 no.4
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    • pp.234-238
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    • 2013
  • Based on a single juvenile specimen (32.3 mm SL) collected from the northeastern coastal waters of Goseong, Gangwon-do, Nautichthys pribilovius was described as the first juvenile record from Korea. This juvenile fish is characterized by having entire body covered with close-set villous prickles, a blunt triangular ridge above orbit with a palmate cirrus, two blunt occipital projections, preopercle with four blunt spines, and a blackish bar below eye reaching lower margin of preopercle. Some morphometric characters related with growth were also discussed.

Cell Viability and Flow Cytometry Analysis of a Novel Antitumor Agent, Heptaplatin in Human Melanoma Cell Line, SK-MEL-28 (신규항암제인 Heptaplatin의 인체 흑색종세포(SK-MEL-28)에 대한 세포생존률 및 유세포 분석)

  • 최수라;명평근
    • YAKHAK HOEJI
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    • v.47 no.6
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    • pp.345-351
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    • 2003
  • Heptaplatin, cis-Malonato[(4R,5R)-4,5-bis(aminomethyl)-2-isopropyl-1,3-dioxolane]platinum(II), is a novel platinum-based antitumor agent with clinical potential against human stomach cancer and the 3rd generation of the cisplatin. This study was performed to study how cisplain, heptaplatin and sunpla which is a mixture of heptaplatin and mannitol (w: w=l : 2) affect cell viability of SK-MEL-28 human melanoma cell line. Heptaplatin ($IC_{50}$/; 95.35 $\mu$M) and sunpla ($IC_{50}$/; 10.95 11M) were less effect than cisplatin (IC $_{50}$; 10.92 $\mu$M) on the SK-MEL-28 cells. By cell cycle analysis using flow cytometry, it was identified that the cells were arrested at G2/M phase by cisplatin, heptaplatin and sunpla, and percentage of cell death group was increased according to increasing of time and concentration. These results suggest that cisplatin, heptaplatin and sunpla are a novel anticancer agent against human melanoma cell.l.

Reconstruction after Wide Excision of Malignant Soft Tissue Tumor in Ankle and Foot (족관절 및 족부에 발생한 연부 조직 악성 종양의 광범위 절제술 후 재건술)

  • Kwon, Young-Ho;Cho, Yool;Kim, Jae-Do;Chung, So-Hak
    • The Journal of the Korean bone and joint tumor society
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    • v.14 no.1
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    • pp.33-43
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    • 2008
  • Purpose: To evaluate the clinical usability of reconstructive methods, and how to select flap after wide excision of malignant soft tissue tumor in ankle and foot. Materials and Methods: The 15 cases shown in the 14 patients (In case of a male patient, reconstruction was performed two times due to local recurrence.) with malignant soft tissue tumor in ankle and foot, who underwent reconstruction after wide excision from March 2000 until March 2007. Oncologic, surgical and functional results were evaluated. Results: The method of reconstruction used were anterolateral thigh perforator flap (5cases), Reversed superficial sural artery flap (4 cases), dorsalis pedis flap (3 cases), local flap (3cases). The defect, mean size was $5.5{\times}5.7\;cm$, was reconstructed with rotation flap or free flap, mean size was $5.9{\times}6.0\;cm$, skin graft for remnant. The mean operation time was 310 minutes (120~540 minutes); it took 256 minutes to reconstruct by rotation flap, and 420 minutes by free flap. As oncologic results, 7 patients were no evidence of disease, 6 patients were alive with disease and 1 patient was expired by pulmonary metastasis at the time of the last follow-up. 4 patients had local recurrence and 4 pateints had distant metastases. As functional results, 14 patients were evaluated with average score of 68.8% using the system of the Musculoskeletal Tumor Society. Conclusion: The dorsalis pedis and reverse superficial sural artery rotation flap which is easy procedure, has less complication and takes short operation time, can be primarily considered to reconstruct a small defect. And the anterolateral thigh perforator flap is suitable for coverage of a large defects after wide excision of malignant soft tissue tumor in ankle and foot.

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Pathological Study of Tumors Occurring in Dog (견종양(犬腫瘍)의 병리학적(病理學的) 검색(檢索))

  • Lim, Chang Hyeong
    • Korean Journal of Veterinary Research
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    • v.15 no.1
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    • pp.27-38
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    • 1975
  • The following tumors occurring naturally in the dog were studied pathologically and discussed briefly. Tumors of the skin and subcutis: Fibroma, Lipoma, Epidermal cyst, Melanosarcoma, Sweat gland adenoma, Mastocytoma (2 cases), Mastosarcoma, and Sebaceous gland carcinoma. Tumors of the spleen and lymph node: Fibrosarcoma of the capsule of spleen, Leiomysarcoma of the spleen, and Lymphosarcoma of the lymph node (2 cases). Tumors of the lung: Bronchogenic carcinoma (3 cases), Adenocarcinoma type, Squamous carcinoma type, and Undifferentiated (round cell) carcinoma type respectively. Tumors of the alimentary tract and liver: Fibroma of the stomach, Hemangioma of the liver, Bile duct carcinoma, Liver cell carcinoma, and Myelogenous leukemia manifested in the liver. Tumor of the peritoneum: Fibrosarcoma. Tumors of the urogenital system: Fibroma of the uterus, Fibroma of the prepuce, Follicular cyst of the ovary, Transmissible venereal tumor of the vagina (6 cases), Carcinoma of the kidney, Adenoma of the prostate (2 cases), and Seminoma of the testis. Tumors of the mammary gland: Mixed tumor (2 cases), and Myoepithelioma. Tumor of the nervous system: Neurofibrosarcoma of the thigh.

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Chitinase Production and Isolation of Serratia plymuthica AL-1 Antagonistic to White Rot Fungi from Allium fistulosum Roots. (대파 뿌리로부터 흑색썩음균핵병균에 길항하는 Serratia plymuthica AL-1의 분리 및 Chitinase의 생산)

  • 주길재;이익희;김진호
    • Microbiology and Biotechnology Letters
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    • v.30 no.2
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    • pp.135-141
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    • 2002
  • This study was carried out to isolate antagonistic bacterium against Sclerotium cepivorum causing Allium fistulosum white rot. Total of 146 strains were isolated from A. fistulosum roots. The isolates were screened for antagonism to S. cepivorum and the isolated strain No. AL-1 was selected among these bacteria. It was identified as Serratia plymuthica based on morphological and physiological characteristics according to the Bergey's mannual of systematic bacteriology and 16S rDNA sequences methods. Serratia plymuthica AL-1 showed broad spectrum of antifungal activities against plant pathogenic fungi Alternaria altrata, Colletotrichum gleosporioids, Phoma sp., Rhizoctonia solani, Sclerotinia sclerotiorum, Stemphylium solani, Fusarium oxysporium niveum but not inhibited Didymella bryoniae. When S. plymuthica AL-1 cultivated in the TSB medium containing 1% colloidal chitin, the high molecular fraction (>10 kDa) have chitinase activity (3.2 units/ml) and the low molecular fraction (<10 kDa) have not chitinase activity. Oppositely, after heat treatment (80℃ for 30 min) of the cultivation supernatant, the high molecular fractions have not antifungal activity but the low molecular fractions have antifungal activity.

Black Hair Follicular Dysplasia in a Shih Tzu (Shih Tzu 견에서 발생한 Black Hair follicular Dysplasia 일례)

  • Kim Sung-ryong;Kim Young-in;Seo Jeong-a;Park Ji-won;Jeong A-young;Lee Keun-woo;Oh Tae-ho
    • Journal of Veterinary Clinics
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    • v.22 no.2
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    • pp.157-159
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    • 2005
  • Two-month old male Shih Tzu weighing 2.1 kg was presented with alopecia in black-haired areas of the skin. The hair loss had been present since five weeks of age. There was no history of pruritus on any part of the body. No other symptoms had been recognized. Physical examination found no abnormalities other than hair loss. Skin examination showed marked alopecia of black-haired area of the body. The white areas appeared to have hair growth of normal density and texture. Affected pigmented areas showed no evidence of skin lesions. Skin scraping and fungal culture were negative. Microscopic examination of plucked black hairs showed marked pigment clumping in the remnants of the follicles and were mainly in telogen phase. But white hairs were normal in various stages of hair growth. The diagnosis of black hair follicular dysplasia was made based on the history, alopecia of the pigmented areas, the confinement of abnormalities to dark areas, and the normal unpigmented areas.

Waxy Black Barley (Hordeum vulgare L.) Cultivar, 'Heuksoojeongchal', with High Yield and Low Amylose Content (아밀로스 함량이 낮은 흑색 다수성 찰보리 '흑수정찰')

  • Kim, Yang-Kil;Lee, Mi-Ja;Kim, Kyong-Ho;Park, Jong-Ho;Park, Tae-Il;Yoon, Young-Mi;Choi, Chang-Hyun;Son, Jae-Han;Kang, Chon-Sik
    • Korean Journal of Breeding Science
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    • v.50 no.4
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    • pp.504-509
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    • 2018
  • A new black barley variety, "Heuksoojeongchal," was developed as a cross between "Keunalbori 1" and "Masankwamaek/Mortoni" at the National Institute of Crop Science, RDA in 2014. Heuksoojeongchal had a longer culm length (89 cm) and a later average heading date and maturity than Seodunchalbori. It also had a spike length of 5.0 cm, $543spikes/m^2$, and 54 grains/spike. The 1000-grain weight of Heuksoojeongchal (36.0 g) was heavier than that of Seodunchalbori. Heuksoojeongchal showed resistance to barley yellow mosaic virus (BaYMV). The yield potential of Heuksoojeongchal was approximately 7% higher than that of Seodunchalbori upland, but the average yield potential was similar in upland and paddy fields. Among the quality characteristics, the ${\beta}-glucan$ content (6.7%) was higher and the amylose content (5.5%) was lower than those of Seodunchalbori. The whiteness of the black barley was low, and its absorption rate and spreadability were similar to those of Seodunchalbori.