• Journal of the Korean Applied Science and Technology
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• v.29 no.4
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• pp.552-560
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• 2012

Drug delivery technologies are patent protected formulation technologies that modify drug release profile, absorption, distribution, and elimination for the benefit of improving product efficacy and safety, as well as patient convenience and compliance. The most commonly used transdermal system is the skin patch using various types of technologies. Compared with other method of dosage, it is possible to use for a long term. It is also possible to stop the drug dosage are stop if the drug dosage lead to side effect. Polysaccharide, such as karaya gum and locust bean gum(LBG)/water-soluble chitosan oligomer(WSCO) were selected as base materials of TDS. Also, these polymers were characterized in terms of enhancers, tacrine contents. Among these polysaccharide, the permeation rate of karaya gum matrix was fastest in tacrine such as lipophilic drug in vitro. We used glycerin, PEG 400, and PEG 800 as enhancers. Therefore, transdermal absorption of tacrine could be improved by changing vehicle composition or by using penetration enhancers. Especially it would be anticipated that the high permeation efficacy could be obtained by using vehicle that has enhancing effect for itself and by adding enhancers to it.

• Journal of Hospice and Palliative Care
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• v.21 no.1
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• pp.33-39
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• 2018

Purpose: This study aimed to identify how an education program on palliative care affects nursing home caregivers' perception of hospice care and attitude towards terminally ill patient care. Methods: This study was conducted using a nonequivalent control group with a pretest-posttest design. The participants were 101 certified care workers: 58 in the experimental group and 43 in the control. The experimental group completed the palliative care education program consisted of 20 hours of classroom training and 20 hours of clinical practicum. An ANCOVA was performed to compare the score changes to outcome variables. Results: Compared with the control group, the experimental group showed significant pretest-posttest differences in both the perception of hospice care (F=21.09, P<0.001) and attitude towards caring for terminally ill patients (F=13.28, P<0.001). Conclusion: These results indicate that the palliative care education program for caregivers is effective in preparing participants to provide hospice/palliative care service. Further study is warranted to explore the effects of this program on palliative caregivers' performance.

• Journal of Korea Technology Innovation Society
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• v.20 no.4
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• pp.1036-1056
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• 2017

The rapid increase of ageing population and chronic disease patients cause high medical expenses, and it led an increased attention to digital healthcare. Smart car technologies for healthcare have been developing to recognize drivers' status and predict diverse driving environments. The present study aimed to understand the research trends of autonomous vehicle technologies of Korea and the United States through time series analysis, network analysis, visualization, and comparison between the two countries. The results suggest that cooperative study needs to be done in common research areas such as driver's safety and algorithms. It is also needed to conduct studies and benchmark about liking technique related to part-to-part and vehicle-to-vehicle as America's competitive advantaged area. In the US, diverse approaches of autonomous vehicle technologies have used to consider the characteristics of various age groups and passengers' health status through sensor, while in Korea, only one aspect, older drivers, is mentioned. Implications for the development direction of autonomous vehicle technologies with competitiveness in considering public health, ethics, and driver's safety and convenience are discussed in detail.

• Journal of the Korean Society of Radiology
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• v.83 no.6
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• pp.1273-1285
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• 2022

Purpose MR neurography (MRN) is an imaging technique optimized to visualize the peripheral nerves. This review aimed to discover an optimized protocol for MRN of the lumbosacral plexus (LSP) and identify evidence for the clinical benefit of lumbosacral plexopathies. Materials and Methods We performed a systematic search of the two medical databases until September 2021. 'Magnetic resonance imaging', 'lumbosacral plexus', 'neurologic disease', or equivalent terms were used to search the literature. We extracted information on indications, MRN protocols for LSP, and clinical efficacy from 55 studies among those searched. Results MRN of the LSP is useful for displaying the distribution of peripheral nerve disease, guiding perineural injections, and assessing extraspinal causes of sciatica. Three-dimensional short-tau inversion recovery turbo spin-echo combined with vascular suppression is the mainstay of MRN. Conclusion Future work on the MRN of LSP should be directed to technical maturation and clinical validation of efficacy.

• The Journal of the Korea Contents Association
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• v.17 no.8
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• pp.241-249
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• 2017

This study was to determine the effectiveness of oral decontamination with chlorhexidine for prevention of ventilator associated pneumonia(VAP) using meta-analysis. MEDLINE, Pubmed, Cochrane library CINAHL and RISS, Koreamed, KISS databases were searched. key words used 'Ventilator-associated pneumonia', 'oral care', 'chlorhexidine' Ninety studies met the inclusion criteria for the meta-analysis. data were analyzed by the Revman 5.3 program of cochrane library and assessed for methodological quality using RoB (The Cochrane's Risk of Bias). The main findings of the current study suggest that chlorhexidine oral care have a positive impact on Ventilator associated pneumonia.

• Journal of the Korean Arthroscopy Society
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• v.15 no.1
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• pp.42-49
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• 2011

Recently, meniscal allograft transplantation has been regarded as a successful procedure in terms of pain relief and functional improvement for the symptomatic patients previously underwent subtotal or total meniscectomy. However, the likelihood of a successful outcome would be reduced by various complications including graft tear, shrinkage, extrusion, infection, progressive chondral injury, and granuloma due to nonabsorbable suture material. Therefore, knee surgeons need to be all aware of the complications and to make an effort to minimize them. The purpose of this article is to review the current literatures regarding clinical results and complications after meniscus allograft transplantation.

• Journal of Korean Orthopaedic Sports Medicine
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• v.2 no.2
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• pp.168-175
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• 2003

Fracture about proximal humerus may be classified as the articular segment or the anatomical neck, the greater tuberosity, the lesser tuberosity, and the shaft or surgical neck. Now, usually used, Neer's classification is based on the number of segments displaced, over 1cm of displaced or more than 45 degrees of angulation , rather than the number of fracture line . Absolute indication of a operative treatment a open fracture, the fracture with vascular injury or nerve injury , and unreductable fracture-dislocation . Inversely, the case that are severe osteoporosis, and eldly patient who can't be operated by strong internal fixation is better than arthroplasty used by primary prosthetic replacement and early rehabilitation program than open reduction and internal fixation. The operator make a decision for the patient who should be taken the open reduction and internal fixation, because it's different that anatomical morphology, bone density, condition of patient. The operator decide operation procedure. For example, percutaneous pinning, open reduction, plate & screws, wire tension bands combined with some intramedullary device are operation procedure that operator can decide . The poor health condition for other health problem, fracture with unstable vital sign and severe osteoporosis , are the relative contraindication. The stable fracture without dislocation is not the operative indication . The radiologic film of the prokimal humerus before the operation can not predict for fracture evaluation. It's necessary to good radiologic film for evaluation of fracture form. The trauma serise is better than the other radiologic film for evaluation. The accessary radiologic exam is able to help for evaluation of bone fragment and anatomy. The CT can be helpful in evaluating these injury, especially if the extract fracture type cannot be determined from plain roenterogram of the proximal humerus, bone of humerus head. If the dislocation is severe anatomically , we could consider to do three dimentional remodelling. The MRI doing for observing of bony morphology before the operation is not better than CT If we were suspicious of vascular injury, we could consider the angiography.

• Therapeutic Science for Rehabilitation
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• v.5 no.2
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• pp.49-55
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• 2016

Objective: The purpose of this study was to look at a systematic review on the relationships of saccadic eye movements and cognition. Through this comprehensive study, we have to compare the studies. Methods: We systematically examined papers published in journal from 1995 to 2015, using KERIS. Main words to examine are saccadic eye movements, cognitive function, cognition, relationship, saccade program, etc. Results: 6 studies were selected, All of them were saccadic eye movements. Eye movements and cognitive function have correlation. Age from 5 to 65 years from the studies, they found the relationships between cognition and saccade(p<.05). However, the results demonstrated some limitations. First, there were variation in large of age spectrum. Second, the populations were small. Therefore, in the future study, saccadic eye movements study apply to variety of interventions to separate experimental group and control group as cohort study, and majority of patients is needed on occupational therapy. Conclusions: In the future study, the use of eye movements apply to a variety of interventions and majority of patients is needed for the effect of cognitive function improvements. If occupational therapists can obtain knowledge and make a protocol for cognitive program.

• Journal of Chest Surgery
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• v.30 no.2
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• pp.158-163
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• 1997

From July 1994 to August 1995, 32 patients underwent coronary artery bypass surgery. There were 14 men and 18 women. The mean age was 59 years (range from 37 to 81 years). Preoperatively 26 patients had unstable angina pectoris and 6 patients had stable angina pectoris. Nine patients had previous myocardial infarction hi tory. Five patients had preoperative left ventricular ejection fraction of 40% or less, The involved risk factors were as follows ; smoking 19 cases, hypertension 16 cases, hypercholesterolemia 14 cases, diabetes mellitus 6 cases, and obesity 3 cases.21 patients had three-vessel disease, 7 patients had two-vessel disease, 2 patients had one-vessel disease and 2 patients had left main coronary artery disease. We performed 103 distal bypasses out of 32 cases, and the mean number of grafts per patients is 3.22. We used arterial grafts (left internal mammary artery,)1, radial artery; 2) in 32% of total grafts. Postoperative complications were low cardiac output, perioperative myocardial infarction, respiratory failure and atrial fibrillation, etc. Early mortality was 6.25% (2/32). The causes of deaths were low cardiac output (1), and perioperative myocardial infarction(1).

• Journal of the Korea Academia-Industrial cooperation Society
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• v.13 no.12
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• pp.5882-5892
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• 2012

This study was performed to examine the effects of Dan Jeon Breathing on stress, sleep disturbance and self-esteem of hemodialysis patients. This study used the nonequivalent control group pretest-posttest design. Before applying the Dan Jeon Breathing program, the patients were divided into the experimental group and the control group, respectively, and were requested to report their self-ratings to measure their stress, sleep disturbance and self-esteem. The Dan Jeon Breathing program was given to experimental groups for 60 minutes a day and 2 times a week for 12 weeks. The data collected from the program were analyzed by means of ${\chi}^2$ test, Fisher's exact probability test, Shapiro-Wilk and t-test. The analyses revealed that the stress(t=-2.95, p=.006) and sleep disturbance(t=-2.13, p=.041) levels of the experimental group decreased after Dan Jeon Breathing compared to those of the control group. The difference in self-esteem(t=2.44, p=.020) level was statistically significant. From the above results, it was verified that Dan Jeon Breathing could be used as nursing intervention for hemodialysis patients to mitigate their stress, sleep disturbance and to improve their self-esteem.