• Korean Chemical Engineering Research
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• v.56 no.4
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• pp.542-546
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• 2018

In this study, the effects of malonic acid-catalyzed pretreatment on the subsequent enzymatic hydrolysis of red macro-algae Gracilaria verrucosa for production of biosugar (total reducing sugar) were investigated. In the hydrothermal pretreatment condition of 300 mM malonic acid, 1:20 solid-to-liquid ratio at $130^{\circ}C$ for 60 min, a 49.2% biosugar yield was achieved. Moreover, by subsequent enzymatic hydrolysis after pretreatment, maximum yield of 64.5% was achieved.

• Journal of Oriental Medical Thermology
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• v.7 no.1
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• pp.1-13
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• 2009

Purpose: To evaluate the hot flush relief efficacy of Yiseontang-gami in climacteric women with hot flushes, a vasomotor symptom. Methods: The 20 subjects who signing on the clinical trial written consent by self-will is registered this clinical trial after decided suitable by selection and exception standard, after take a medical experiment and checkup according to clinical trial plan. Registered subject should valuated by settled schedule after take the testing medicine(Yiseontang-gami)during thirty-day. The evaluating indexes of this trial are hot flush VAS, hot flush frequency, hot flush consistence time, sweating VAS, palpitation VAS, sleep disturbance VAS, MRS, MENQOL, PGA. Results: The results were as follows 1. 4 subjects dropped out of the clinical trial and 16 subjects completed it. 2. After Yiseontang-gami treatment, hot flush VAS, hot flush frequent, sweating VAS, Palpitation VAS, sleep disturbance VAS improved significantly. 3. After Yiseontang-gami treatment, hot flush consistence time was not improved significantly. 4. After Yiseontang-gami treatment, blood test value were not different significantly. Conclusion: In this clinical trial we consider that Yiseontang-gami is suitable treatment for the hot flushes and related symptoms.

• Journal of Oriental Medical Thermology
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• v.7 no.1
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• pp.37-43
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• 2009

Purpose: The purpose of this study is to identify the clinical effect of Red Ginseng in the treatment of postmenopausal hot flushes. Methods: We studied 49 women from 45 to 55 years old who complained hot flushes. We randomly divided women into two groups, We treated one group with red ginseng capsule, and treated another group with placebo for 2 months. patients recorded the frequency of the hot flush on an everyday basis. And we measured temperature of patient's face by DITI. Results: Red ginseng and Placebo treated group significantly decreased the frequency of the hot flush. After treatment, the temperature on the cheekbones who treated by red ginseng get lower than before treatment. But there is no statistically difference between red ginseng and placebo. Conclusion: This study shows that both red ginseng and placebo have remarkable effects on patients, but red ginseng is not better than placebo.

• The Journal of Korean Obstetrics and Gynecology
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• v.21 no.1
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• pp.168-178
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• 2008

Purpose: To verify the relationship of SA2000E results and acupuncture treatment efficacy on postmenopausal women. Methods: Longitudinal analyze relationship of the SA2000E results and hot flush VAS score changes of a clinical trial participants in 2006. Results: Someone who has high Vaso-aging degree by SA2000E represented better hot flash VAS decreasing efficacy. And the diminution rate of hot flash VAS, after 1week from the 1st treatment day was 0.311(p=0.0001), and finally 0.672(p = 0.0396). There are no statistical differences between study group and control group. Conclusion: Clinical trial participant who has better Vaso-physiological function present more hot flash reduce efficacy by acupuncture therapy. Vaso-aging degree by SA2000E could be use as a predictor of acupuncture hot flash treatment result.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.30 no.4
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• pp.585-588
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• 1997

The polymerase chain reaction (PCR) technique was used to distinguish from two morphologically similar red algal species; Acrosorium polyneurum and A. yendoi. Total DNA was extracted by the LiCl method. The extracted DNA (15 ng) in a $25{\mu}\ell$ reaction volume was amplified by the PCR technique using primers covering with mitochondrial D-loop gene, nuclear rDNA internal transcribed spacer (ITS), and nuclear rDNA external transcribed spacer. A. yendoi could be distinguished from A. polyneurum on the producible basis of amplified ITS fragment of 650 bp.

• Korean Journal of Environmental Biology
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• v.19 no.2
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• pp.107-112
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• 2001

A tissue biosensor was developed for the continuous determination of $Na^+$ channel blockers. The proposed sensor was applied to the determination of Na+ channel blockers in seaweed. It was found that $Na^+$ channel blocker content displayed seasonal variation; it was high from February to April and decreased thereafter (May - August). From these results the present proposed method may be used for high sensitive determination of $Na^+$ channel blockers contained in the seaweed organisms and environments. Therefore, it may be important to monitor $Na^+$ channel blocker content of seaweed throughout the year.

• Journal of the Korean Applied Science and Technology
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• v.11 no.1
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• pp.71-77
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• 1994

In order to review industrial application of amphoteric surfactants, new types of hydroxy sulfobetaine, 3-(N, N-dimethyl N-dimethyl-N-alkylammonio)-2-hydroxy-1-propane sulfonate and 3-(N, N-dimethyl N-acylammonio)-2-hydroxy-1-propane sulfonate were prepared by the reaction of quaternized sodium 1-chloro-2-hydroxy-3-propane sulfonate with N, N-dimethyl-N-alkylamine and N, N-dimethyl N-acylamido propylamine that have a straight chain radical of 12, 18 carbon atoms respectively in the presence of alkali catalyst. All the reaction products could be separated by means of column and thin layer chromatography, and the yields of all products ranged in $85{\sim}90%$, the structure of them could be confirmed from IR and $^{1}H$-NMR spectra.

• Microbiology and Biotechnology Letters
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• v.45 no.4
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• pp.316-321
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• 2017

Hyperthermal acid hydrolysis pretreatment of Eucheuma denticulatum was carried out using 12% (w/v) seaweed slurry and 90 mM $H_3PO_4$ at $150^{\circ}C$ for 10 min. The use of Candida lusitaniae with adaptive evolution was evaluated for ethanol fermentation. The levels of ethanol production by separate hydrolysis and fermentation (SHF) at 72 h with non-adapted and adapted C. lusitaniae were 10.1 g/l with ethanol yield ($Y_{EtOH}$) of 0.23, and 18.1 g/l with $Y_{EtOH}$ of 0.45, respectively. Adaptive evolution was employed in this study to improve the efficiency of ethanol fermentation. Development of the SHF process could enhance the overall ethanol fermentation yields of the red seaweed E. denticulatum.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.28 no.1
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• pp.160-168
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• 2015

Objective : The purpose of this study is to report the effect of Gagamhwanggeum-tang on emotional facial flush. Methods : This case study was done on 3 Facial Flush patients who have visited Korean Medicine Clinic. Gagamhwanggeum-tang was prescribed to all 3 patients and evaluated the symptom change through photographs and questionnaire. Investigator's Global Assessment(IGA) was used to evaluate the objective symptom and Visual Analogue Scale(VAS) was used to evaluate the subjective change Results & Conclusion : The IGA and VAS were decreased in 3 patients in our study. Most symptoms of 3 patients were improved. As a result of examining IGA, VAS scores and photographs, Gagamhwanggeum-tang can be effective on emotional facial flush in 3 case in our study.

• Proceedings of the Korea Technical Association of the Pulp and Paper Industry Conference
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• 2007.11a
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• pp.93-102
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• 2007

Biocomposite was organized with biodegradable polymer and natural fiber that has potential to be used as replacement for glass fiber reinforced polymer composite with the benefits of low cost, low density, acceptable specific strength, biodegradability, etc. Until now, non-wood fibers have been used as reinforcements of biocomposite which are all plant-based fibers. The present study focused on investigating the fabrication and characterization of biocomposite reinforced with red algae fiber. The bleached red algae fiber(BRAF) showed very similar crystallinity to the cellulose. It has high stability against thermal degradation (maximum thermal decomposition temperature of 359.3$^{\circ}C$) and thermal expansion. Biocomposites reinforced with BRAF have been fabricated by a compression molding method and their mechanical and thermal properties have been studied. The storage modulus and the thermomechanical stability of PBS matrix are markedly improved with reinforcing the BRAF. These results support that the red algae fiber can be used as an excellent reinforcement of biocomposites as "green-composite" or "eco-composite".