• Journal of Plant Biotechnology
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• v.43 no.3
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• pp.347-358
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• 2016

Brassinosteroid (BR), a plant steroid hormone, plays key roles in numerous growth and developmental processes as well as tolerance to both abiotic and biotic stress. To understand the biological networks involved in BR-mediated signaling pathways and stress tolerance, we performed comparative genome-wide transcriptome analysis of a constitutively activated BR bes1-D mutant with an Agilent Arabidopsis $4{\times}44K$ oligo chip. As a result, we newly identified 1,091 (562 up-regulated and 529 down-regulated) significant differentially expressed genes (DEGs). The combination of GO enrichment and protein network analysis revealed that stress-related processes, such as metabolism, development, abiotic/biotic stress, immunity, and defense, were critically linked to BR signaling pathways. Among the identified gene sets, we confirmed more than a 6-fold up-regulation of NB-ARC and FLS2 in bes1-D plants. However, some genes, including TIR1, TSA1 and OCP3, were down-regulated. Consistently, BR-activated plants showed higher tolerance to drought stress and pathogen infection compared to wild-type controls. In this study, we newly developed a useful, comprehensive method for large-scale identification of critical network and gene sets with global transcriptome analysis using a microarray. This study also showed that gain of function in the bes1-D gene can regulate the adaptive response of plants to various stressful conditions.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.7 no.6
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• pp.12-20
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• 2008

Recent wireless communication technologies are envisioned as an innovative alternative to solve transportation problems. On ad hoc networks, as a wireless communication technology, nodes can communicate data without any infrastructure. In particular, vehicular ad hoc networks (VANETs), a specific ad hoc network applied to vehicles, enable vehicles equipped with a communication device to form decentralized traffic information systems in which vehicles share traffic information they experienced. This study investigated traffic information dissemination in a VANET-based traffic information system. For this study, an integrated transportation and communications simulation framework was developed, and experiments were conducted with real highway networks and traffic demands. The results showed that it took 3 minutes in the low traffic density situations (10 vehicle/lane.km) and 43 seconds in the high traffic density condition (40 vehicle/lane.km) to deliver traffic information of 5km away with 10% market penetration rate. In uncongested traffic conditions, information seems to be disseminated via equipped vehicles in the opposite direction. In congested traffic conditions, the sufficient availability of equipped vehicles traveling in the same direction reduces the chance to use vehicles in the opposing direction even though it is still possible.

• Journal of the Korean association of regional geographers
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• v.21 no.3
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• pp.489-502
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• 2015

Sometimes called the Silicon Fen, the Cambridge cluster is well known as the most innovative hi-tech cluster in the world. This paper attempts to explore the evolutionary dynamics of the Cambridge cluster, drawing upon the triple-helix approach. To understand the evolutionary dynamics of the Cambridge cluster, it is important to examine the role and impact of the University of Cambridge, which is conceived as one of the best higher educational institutions in the world. The Cambridge cluster has been evolved on the basis of a strong university-industry relationship. University spin-outs have a long tradition in Cambridge with the history of more than a century, and they have played a critical role in making the cluster more innovative. Business networks and social capital molded for a long time in the region become a foundation for active local spin-out activities. However, since 2000 the central government started steadily to require British universities to be an entrepreneurial university, with the purpose of the reduction of university subsidies. As a result of this, spin-out activities in the Cambridge cluster show a sharp decline, which is a factor of threatening the dynamic evolution of the cluster.

• Journal of Internet Computing and Services
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• v.15 no.3
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• pp.63-69
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• 2014

For the safety messages in IEEE 802.11p vehicles network environment(WAVE), strict periodic beacon broadcasting requires status advertisement to assist the driver for safety. WAVE standards apply multiple radios and multiple channels to provide open public road safety services and improve the comfort and efficiency of driving. Although WAVE standards have been proposed multi-channel multi-radio, the standards neither consider the WAVE multi-radio environment nor its effect on the beacon broadcasting. Most of beacon broadcasting is designed to be delivered on only one physical device and one control channel by the WAVE standard. also conflict-free channel assignment of the fewest channels to a given set of radio nodes without causing collision is NP-hard, even with the knowledge of the network topology and all nodes have the same transmission radio. Based on the latest standard IEEE 802.11p and IEEE 1609.4, this paper proposes an interference aware-based channel assignment algorithm with Nash bargaining solution that minimizes interference and increases throughput with wireless mesh network, which is deigned for multi-radio multi-cahnnel structure of WAVE. The proposed algorithm is validated against numerical simulation results and results show that our proposed algorithm is improvements on 8 channels with 3 radios compared to Tabu and random channel allocation algorithm.

• 한국HCI학회:학술대회논문집
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• 2006.02c
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• pp.854-858
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• 2006

디지털화의 가속, 고속 통신 인프라의 확대 등으로 전자, 정보 통신 기기들이 단일 네트워크로 연결되어 영상 및 음향 정보를 서로 공유할 수 있으며, 생활 공간 내에서 실생활의 질 향상을 위한 지능적 정보 서비스와 자연스럽고 편한 내추럴 인터페이스 기술에 의한 지능형 반응 정보 서비스 공간 기술이 중요한 이슈로 등장하고 있다. 본 연구에서는 지능형 반응 공간의 물리적 객체로서 학교, 연구 기관 및 회사 등의 회의실을 선정한다. 그리고, 이를 대상으로 회의 참여자들이 자연스럽고 편리하게 의견 교환, 관련 자료 및 정보 처리를 할 수 있는 시스템 구축을 위한 아키텍처에 대하여 논의한다. 본 연구에서 제안하는 시스템 아키텍처는 회의와 관련된 문서나 회의 내용 등의 정보를 실감 가시화 노드로 추상화되고 메타 정보화함으로써 전체 회의 내용의 파악과 회의 정보에 대한 체계적이고 논리적인 관리를 가능하게 한다. 또한 여러 사람의 공동 작업을 필요로 하는 정보 또는 문서에 대한 동시 편집 기능과 자연스러운 동작에 의한 데이터 조작을 지원하는 실감 워크벤치 및 워크스크린 기술, 정보 핸들링의 다양성과 조작의 편리성을 위한 실감 아이콘에 의하여 자연스럽고 편리한 회의를 가능하게 한다. 그리고, 이러한 요소 기술들이 에이전트에 의해 회의 프로세스 및 요소 기술들의 시스템적 통합을 가능하게 한다.

• Proceedings of the Korea Water Resources Association Conference
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• 2009.05a
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• pp.496-500
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• 2009

소하천은 하천 네트워크의 최상류에 넓게 소재하는 하천이다. 본 연구의 목적은 올바른 소하천 수생태계 관리방안을 도출하기 위하여 소하천의 건강성을 분석하고 현행 소하천 관리제도의 개선점을 모색하는 것이었다. 본 연구에서는 다음과 같은 분석방법을 이용하였다. 첫째, 2007년 한강수계 소하천 28개 지점에서의 부착조류($DAI_{PO}$, TDI), 저서성 대형무척추동물(KSI), 어류(IBI), 서식환경, 수변환경 등 6개 항목에 대한 수생태 건강성 조사결과를 토대로 공간적 분포와 수질현황을 조사하여 소하천에 대한 종합적인 건강성 평가를 실시하였다. 둘째, 분석대상지역을 각각 소하천 구간스케일(28개 지점)과 유역스케일(팔당호, 안성천 유역)로 선정, 하천차수도(1:25,000)를 활용하여 해당 구간과 유역의 소하천도를 작성하였다. 셋째, 작성된 소하천도 는ArcGIS(ver. 9.3)에서 30, 60, 90, 120, 150-m Buffering을 하였다. 다음으로 소하천 구간은 중분류(23개 항목, $2000{\sim}2006$ 또는 2007년) 토지피복도를, 팔당호 및 안성천 유역의 소하천은 대분류(8개 항목, $1975{\sim}2000$년) 토지피복도를 적용하여 분류항목별 면적변화비율을 산정하였다. 끝으로 소하천 정비에 대한 제도적 문제점을 분석하여 소하천 관리의 개선점을 연구하였다. 그 연구 결과, 첫째 연구대상 소하천(28개)의 건강성은 도심 소하천에서 가장 낮게 조사되었고, 일부 소하천은 비록 상류에 위치함에도 불구하고 부착조류의 유기물, 영양염류 평가가 낮게 평가되었다. 둘째, 소하천 구간 스케일의 수변토지피복변화 분석결과 소하천 수생태 건강성은 거시적으로 산림, 도시화, 밭 등의 피복변화에 민감한 것으로 나타났으며 도시화 피복변화의 영향은 수변 30m에서 60m보다 3배 정도 큰 것으로 나타났다. 유역 스케일 분석에서는 상대적으로 도시화가 많이 진행된 안성천 유역의 소하천이 팔당호 유역보다 낮은 건강성일 것으로 예측되었다. 결론적으로 적절한 소하천 수변관리는 지역 하천의 건강성을 온전히 회복시키고 개선 유지하기 위한 중요한 수단들 중에 하나이며 수변토지피복의 변화율은 (소)하천 건강성 또는 유역관리의 지표로 활용될 수가 있는 것으로 조사되었다. 이와 더불어 본 연구를 통해 소하천 복원 및 관리는 소하천 특성을 고려한 장기적인 계획과 관리대상의 우선순위를 바탕으로 점진적인 대안마련이 필요할 것으로 사료된다.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.19 no.12
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• pp.2779-2784
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• 2015

The prediction of the accurate traffic information can provide an optimal route from the place of departure to a destination, therefore, this makes it possible to obtain a saving of time and money. To predict traffic information, we use a Bayesian network method based on probability model in this paper. Existing researches predicting the traffic information based on a Bayesian network generally used to study the data for all time. In this paper, however, only data corresponding to same time and day of the week to predict selectively will be used for learning. In fact, the experiment was carried out for 14 links zone in Seoul, also, the accuracy of the prediction results of the two different methods should be tested with MAPE (Mean Absolute Percentage Error) which is commonly used. In view of MAPE, experimental results show that the proposed method may calculate traffic prediction value with a higher accuracy than the method used to learn the data for all time zones.

• Journal of Korean Society of Transportation
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• v.33 no.2
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• pp.192-203
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• 2015

Pedestrians not only walk along pedestrian pathways, but also choose unusual routes such as passing through buildings or crossing large scale open spaces. This study defines these unusual paths as social path, and includes them into one of the pedestrian road categories. Previous pedestrian accessibility and route choice studies could not evaluate correctly the space connectivity or optimal route because the social path was not considered properly. Therefore, this study analyzes the effectiveness of the social path in view of space connectivity focused on Coex and Seoul stations in Seoul, which are representative transit oriented development(TOD) areas. Global integration, which is widely used in network analysis, is selected (as performance index) to identify the space hierarchy and define new pedestrian links. The study results show that the network connectivity is improved especially in the main streets and social paths. This study demonstrated that the social path should be considered in finding the pedestrian optimal route from the practical perspective.

• Development and Reproduction
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• v.9 no.1
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• pp.1-5
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• 2005

The hypothalamo-pituitary-gonadal hormone axis is centrally controlled by a complex regulatory network of excitatory and inhibitory signals, that is dormant during infantile and juvenile periods and activated at puberty. The kisspeptins are the peptide products of the KiSS-1 gene and the endogenous agonists for the G protein-coupled receptor 54(GPR54). Although KiSS-1 was initially discovered as a metastasis suppressor gene, a recent evidence suggests the KiSS-1/GPR54 system is a key regulator of the reproductive system. Yet the actual role of the KiSS-1/GPR54 system in the neuroendocrine control of gonadotropin secretion remains largely unexplored, the system could be the first missing link in the reproductive hormonal axis. Central or peripheral administration of kisspeptin stimulates the hypothalamic-pituitary-gonadal axis, increasing circulating gonadotropin levels in rodents, sheep, monkey and human models. These effects appear likely to be mediated via the hypothalamic GnRH neuron system, although kisspeptins may have direct effects on the anterior pituitary gland. The loss of function mutations of the GPR54(GPR54-/-) have been associated with lack of puberty onset and idiopathic hypogonadotropic hypogonadism(IHH). So kisspeptin infusion may provide a novel mechanism for HPG axis manipulation in disorders of the reproductive system.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.7
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• pp.599-610
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• 2017

This study aims at establishing a knowledge transfer system between academics and industries in the Chungnam Region. We analyze the difficulties encountered by the technology licensing offices of universities in the Chungnam Region through a practical analysis of the current situation regarding the transfer of the knowledge developed in the universities. The problems found included the poor circumstances of the TLO of the universities, very limited number of requests for knowledge transfer by the companies, distrust of university technologies and the absence of related networks and platforms. Especially, there is insufficient concern and recognition of the regional actors in the knowledge transfer system. Therefore, in order to improve the regional competitiveness, these problems should be fixed by enacting suitable government policies.