• Title/Summary/Keyword: 혈액특성

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Effect of Airborne Lead Concentration Characterized by Size on Blood Lead and Their Relationships (납 흡수에 영향을 미치는 요인 분석: 납 크기 특성과 혈액중 납과의 관계)

  • Park, Dong-Uk;Ha, Kwon-Chul
    • Journal of Environmental Health Sciences
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    • v.31 no.4 s.85
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    • pp.316-321
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    • 2005
  • 4개 업종(축전지제조업, 광명단 제조업, 2차 제련업, 라디에타 제조업)에서 근무하는 총 100명의 근로자를 대상으로 8단계다단충돌기(eight stages personal cascade imparter)에 의한 입자 크기 별 납농도를 측정하였다 크기 별 납 농도는 총납(PbA), 흡입성납(IPM-PbA), 흉곽성납(TPM-PbA), 호흡성납(RPM-PbA), $1{\mu}m$ 미만의 납$(Pb_{1\mu})$ 그리고 $1{\mu}m$ 이상의 소화성납$(Pb_{ing})$이었다. 동일한 근로자(100명)를 대상으로 혈액에서 납농도를 측정하였다. 혈액 중 납은 원자흡광광도계(atomic absorption spectrometry)의 Zeeman effect graphite furnace를 이용하여 분석하였다. 총 납의 노출농도는 노출기준$(50\;ug/m^3)$을 크게 초과하였다. 평균 호흡성 납 노출농도$(115.7\;ug/m^3)$ 총 납의 노출기준을 훨씬 초과하였다. $1{\mu}m$미만의 납$(Pb_{1\mu})$ 노출농도의 범위는 0.7에서 $(492.2\;ug/m^3)$이나 되었다. 근로자의 $46\%$가 혈액 중 납 농도 40 ug/dL을 초과하였다. 60 ug/dL을 초과한 경우도 $13\%$나 되었다. 입자 크기가 큰 납인 총납, 흡입성 납 그리고 호흡성 납 농도는 혈액 중 납 농도와 유의한 상관을 보였다(p<0.0001). 그러나 가장 높은 상관은 $1{\mu}m$미만의 납$(Pb_{1\mu})$ 혈액 중 납과의 관계였다. T-test에서 $50ug/m^3$이상의 호흡성 납을 나타낸 근로자 그룹과 $50ug/m^3$ 이하의 근로자 그룹간에의 혈액 중 납 농도는 유의한 차이가 있는 것으로 나타났다(p=0.000). 이러한 연구결과는 입자크기 구분이 없는 현재의 총납에 의한 노출기준과 측정방법은 미세 납 먼지에 노출되는 근로자의 납흡수를 보호하는데 한계점이 있다는 것을 의미한다. 향후 납 입자크기는 물론 근로자의 개인적인 위생과 작업내용 등을 변수로 납 흡수에 영향을 미치는 종합적인 요인을 찾아내는 연구를 진행할 필요가 있다.

A Study of in-vitro Performances of the Intracardiac Axial Flow Pump (심장내 이식형 축류 혈액펌프의 in-vitro특성에 관한 연구)

  • 김동욱;삼전부호희
    • Journal of Biomedical Engineering Research
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    • v.19 no.1
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    • pp.33-38
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    • 1998
  • The intracardiac axial flow pump has been developed This device has several advantages: it fits well anatomically, its blood-contacting surface is small, and it is implanted as easily as an artificial heart valve replacement. The axial flow pump consists of an impeller and a motor, both of which are encased in a housing. Two types of impeller with 4 vanes and 6 vanes are used. Sealing of the motor shaft is achieved by means of a ferrofluidic seal. A flow of 5$\ell$/min was obtained at a differential pressure of 100mmHg with a motor speed of 7091rpm with the 4-vane impeller and 6402rpm with the 6-vane impeller. Sealing was kept against a pressure of 150mmHg at 7000rpm with the 4-vane impeller and 6402rpm with the 6-vane impeller. Sealing was kept against a pressure of 150mmHg at 7000rpm over 24 hours. The index of hemolysis was 0.056 with the 4-vane impeller and 0.214 with the 6-vane impeller. The intracardiac axial flow pump is a very promising circulatory support.

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Evaluation of Epidemic Characteristics of Extended Spectrum $\beta$-Lactamase Producing Bacteria Isolated from Blood Cultures (혈액배양(血液培養)에서 분리(分離)된 Extended Spectrum $\beta$-Lactamase 생성균(生成菌)의 특성(特性) 고찰)

  • Seo, Choong-Won;Kim, Sang-Ha;Kim, Young-Kwon
    • Proceedings of the KAIS Fall Conference
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    • 2009.05a
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    • pp.579-582
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    • 2009
  • 본 연구는 혈액에서 분리되는 미생물의 균종과 항균제 감수성 검사 결과 양상은 환자의 일반적 특성에 따라 다르므로 혈액배양 결과를 분석한 자료는 감염증 환자의 경험적 치료를 위한 중요한 근거가 되고, 특히 ESBL을 생성하는 균주의 경우 항균제의 사용과도 밀접한 관련이 있어 이 연구를 하게 되었다. 대상은 중부지역 일개대학병원의 입원 및 외래환자의 2004-2006년 혈액배양 결과와 항균제 내성 결과를 분석하였다. 혈액배양은 Bact/Alert 3D (North Carolina, Durham, USA)를 이용하여 성인에서는 Bact/Alert S(Aerobic)(Biomerieux Brazil S.A)와 Bact/Alert SN(Anaerobic)(Biomerieux Brazil S.A) 배지를 사용하였고, 소아에서는 Bact/Alert PF (Biomerieux Brazil S.A)배지를 사용하여 5일간 배양하였고, 항균제 감수성 검사는 자동화 동정 및 감수성 장비인 VITEK (BioMerieux vitek. Hazelwood. Missori. USA)을 이용하였다.

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Study on blood compatibility of diamond-like carbon and titanium nitride films (Diamond-like carbon 및 titanium nitride 박막의 혈액적합성 연구)

  • Yun Ju-Young;Bae Jin-Woo;Park Ki-Dong;Goo Hyun-Chul;Park Hyung-Dal;Chung Kwang-Wha
    • Journal of the Korean Vacuum Society
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    • v.14 no.3
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    • pp.165-170
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    • 2005
  • There is an increasing interest in developing novel coating to improve the blood compatibility of medical implants. Diamond-like carbon(DLC) and titanium nitride(TiN) films have been proposed as potential biomedical coatings due to their chemical k physical properties and moderate biocompatibility. To study the correlation between blood compatibility and physical properties of the films, the fibrinogen adsorption on the surface as well as morphology & wettability were investigated. The quantity of fibrinogen adsorption are Tower for TiN than DLC, which correlates with a higher hydrophilicity of TiN film. To reduce the quantity of fibrinogen adsorption on the film, plasma treatment and furnace annealing were performed, respectively. With the use of oxygen plasma and furnace annealing, the amount of fibrinogen adsorption on TiN film was remarkably reduced, while there was no decrease of the quantity with DLC.

Interaction of Blood Flow and Leaflet Behavior in a Bileaflet Mechanical Heart Valve (기계식 인공심장판막(MHV)에서의 혈액유동과 판막운동의 상호작용)

  • 최청렬;김창녕;권영주
    • Journal of Biomedical Engineering Research
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    • v.21 no.5
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    • pp.505-512
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    • 2000
  • 기계식 인공심장판막을 통한 혈액의 유동과 이 유동에 관련된 판첨의 거동특성을 수치해석기법을 이용하여 연구하였다. 혈액은 맥동류, 층류, 비압축성 유동으로 가정하였으며 유체-고체의 상호작용을 고려하기 위하여 혈액의 유동방정식과 고체의 운동방정식이 동시에 계산되었다. 심실과 대동맥에서의 압력파형을 경계조건으로 사용하였다. 연구의 결과로서 혈액유동과 판첨의 거동이 예측되었으며, 판막을 통한 3개의 제트가 발견되었으며 vortex가 판첨의 끝단에서 발생하여 하부로 흘러가는 것이 관찰되었다. 판첨의 닫힘 거동은 열림 거동에 비하여 2배정도 빠르게 진행되었으며 sinus에서 2개의 큰 vortex가 관찰되었다. 유체-고체 상호작용을 고려하는 본 연구방법은 향후 판막의 연구와 개발에 매우 유용할 것으로 판단된다.

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Effects of fermented milk substituted for creep feed on growth performance, diarrhea score and blood profiles in lactating piglets (포유자돈에 있어서 포유자돈용 발효유의 급여가 생산성, 혈액특성, 및 설사지수에 미치는 영향)

  • Kim, Seung Cheol;Kim, Hyun-Soo;Heo, Jung-Min;Kim, In-Ho
    • Korean Journal of Agricultural Science
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    • v.42 no.4
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    • pp.375-382
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    • 2015
  • In the present study, offsprings of 14 sows were used to evaluate the effect of fermented milk substituted for creep feed to analyze its effect on growth performance, diarrhea score and blood profiles. The piglets of sows were randomly allocated into 1 of 2 treatments (1 treatment separated piglets of 7 sows). The dietary treatments includes: CF (creep feed) and FM (fermented milk). The CP and FM diets were given from 3 d after piglets were born to the day of weaning (21 d after piglets were born). No significant difference (P>0.05) were observed in number of born piglets, weaning pigs, survival rate, body weight of piglets at d 0, 7, 14, and 21, ADG and ADFI. At d 21, piglets fed with CP had a higher (P<0.05) IgG compared with piglets fed with FM. No significant difference (P>0.05) was observed in WBC among the treatments at d 21. At d 6, piglets fed with CP had a lower (P<0.05) number of diarrhea piglets compared to piglets fed with FM. In conclusion, FM substituted for CP had no adverse effect on growth performance in lactating piglets.

Effect of Blood Donation on the Donor's Hemorheological Properties (헌혈이 헌혈자의 혈유변학적 지표에 미치는 영향)

  • Lee, Byoung Kwon
    • The Korean Journal of Blood Transfusion
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    • v.29 no.3
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    • pp.229-239
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    • 2018
  • The circulatory system is closely related to the inter-relationship between the anatomy of the heart and blood vessels, and the fluid dynamic properties of blood. The physical properties of blood, which affect blood flow, are called hemorheologic factors. Hemorheologic factors, such as blood viscosity and erythrocyte aggregation, are influenced mainly by hematocrit. A higher hematocrit level results in an increase in blood viscosity, erythrocyte aggregation, which impedes the circulation itself, and tissue oxygenation. An excess of serum ferritin causes injury to vascular endothelial cells and erythrocytes via oxygen free radicals. In addition, an excess of blood can aggravatee the adverse effects of the hemorheologic parameters and induce atherogenesis, microcirculatory disturbances, and major cardiovascular events. A preventive and therapeutic approach with a phlebotomy or blood donation has been stimulated by the knowledge that blood loss, such as regular donations, is associated with significant decreases in key hemorheologic variables, including blood viscosity, erythrocyte aggregation, hematocrit, and fibrinogen. Major cardiovascular events have been improved in regular blood donors by improving blood flow and microcirculation by decreasing the level of oxidative stress, improving the hemorheologic parameters, and reducing the serum ferritin level. Confirmation of the positive preventive and therapeutic effects of blood donations on cardiovascular disease by a well-designed and well-controlled Cohort study may be good news to patients with cardiovascular disease or at risk of these diseases, as well as patients who require a transfusion.

Research on the Self-Esteem, Resilience, and Quality of life of Hemodialysis Patient (혈액투석 환자의 자아존중감, 극복력 및 삶의 질에 관한 연구)

  • Song, Chung-Sook;Jung, Sun-Young
    • Journal of Convergence for Information Technology
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    • v.10 no.11
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    • pp.77-86
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    • 2020
  • The research was to identify difference of values of the self-esteem, resilience and quality of life of hemodialysis patients. The survey was conducted to collect data between February 1 and 28 of 2020. SPSS/WIN 20 program was used to perform descriptive, correlation, and multiple regression analyses. In the correlation analysis, Cohabitation form(r=.262, p<.01), Economic status(r=.278, p<.01), Current health status recognition(r=.294, p<.01), Self-esteem(r=.547, p<.01), Resilience(r=637, p<.01) turned out to be influential factor for self-esteem, resilience, and quality of life according to general and disease of characteristics. Therefore, on the basis of this research, it is meaningful to provide basic data for the development of nursing interventions that allow one to embrace one's health condition and find the meaning of life in order to improve the quality of life of hemodialysis patients.