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Study on blood compatibility of diamond-like carbon and titanium nitride films  

Yun Ju-Young (Vacuum center, Korea Research Institute of Standards and Science)
Bae Jin-Woo (Department Molecular Science & Technology, Ajou University)
Park Ki-Dong (Department Molecular Science & Technology, Ajou University)
Goo Hyun-Chul (Dentkist, Inc. Biomaterials Research Institute)
Park Hyung-Dal (Pharmaceutical Exam. Div. Korean Intellectual Property office)
Chung Kwang-Wha (Vacuum center, Korea Research Institute of Standards and Science)
Publication Information
Journal of the Korean Vacuum Society / v.14, no.3, 2005 , pp. 165-170 More about this Journal
Abstract
There is an increasing interest in developing novel coating to improve the blood compatibility of medical implants. Diamond-like carbon(DLC) and titanium nitride(TiN) films have been proposed as potential biomedical coatings due to their chemical k physical properties and moderate biocompatibility. To study the correlation between blood compatibility and physical properties of the films, the fibrinogen adsorption on the surface as well as morphology & wettability were investigated. The quantity of fibrinogen adsorption are Tower for TiN than DLC, which correlates with a higher hydrophilicity of TiN film. To reduce the quantity of fibrinogen adsorption on the film, plasma treatment and furnace annealing were performed, respectively. With the use of oxygen plasma and furnace annealing, the amount of fibrinogen adsorption on TiN film was remarkably reduced, while there was no decrease of the quantity with DLC.
Keywords
biomaterials; blood compatibility; hydrophilicity; diamond-like carbon; titanium nitride;
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1 S. Mandl and B. Rauschenbach, Surface and Coatings Technology 156, 276 (2002)   DOI   ScienceOn
2 F. Z. Cui and D. J. Li, Surface and Coatings Technology 131, 481 (2000)   DOI   ScienceOn
3 O. Durand-Drouhin, M. Benlahsen, M. Clin, and R. Bouzerar, Applied Surface Science, ??? (2003)
4 H. Clemens, D. W. Schubert, G. Dehm, C. Scheu, J. L. Buttstaedt, Applied Surface Science 219, 329 (2003)   DOI   ScienceOn
5 L. Sirghi, T. Aoki, and Y. Hantanaka, Thin Solid Films 422, 55 (2002)   DOI   ScienceOn
6 M. Takeuchi, Y. Onozaki, Y. Matsumira, H. Uchida, and T. Kuji, Nuclear Instruments and Methods in Physics Research, B 206, 259 (2003)   DOI   ScienceOn
7 M. I. Jones, I. R. McColl, D. M. Grant, K. G. Parker, and T. L. Parker, Diamond and Related Materials 8, 457 (1999)   DOI   ScienceOn
8 K. Christensen, R. Larsson, H. Emanuelsson, G. Elgue, and A. Larsson, Thrombosis Research 115, 245 (2005)   DOI   ScienceOn
9 N. Huang, P. Yang, Y. X. Leng, J. Y. Chen, H. Sun, J. Wang, G. J. Wang, P. D. Ding, T. F. Xi, and Y. Leng, Biomaterials 24, 2177 (2003)   DOI   ScienceOn
10 F. Berme, J. Buttstaedt, and G. Emig, Thin Solid Films 377-378, 755 (2000)
11 O. F. Bertrand, R. Sipehia, R. Mongrain, J. Rodes, J. Tardif, L. Bilodeau, G. Cote, and M. G. Bourassa, J Am Coll Cardiol. 32, 562 (1998)   DOI   ScienceOn
12 K. D. Park, W. K. Lee, J. Y. Yun, D. K. Han, S. H. Kim, Y. H. Kim, H. M. Kim, and K. T. Kim, Biomaterials 18, 47 (1997)   DOI   ScienceOn
13 K. M. Hansson, S. Tosatti, J. Isaksson, J. Wettero, M. Textor, T. L. Lindahl, and P. Tengvall, Biomaterials 26, 861 (2005)   DOI   ScienceOn
14 E. Grenadier, A. Roguin, I. Hertz, B. Peled, M. Boulos, E. Nikolsky, S. Amikam, A. Kerner, S. Cohen, and R. Bayer, Catheterization and Cardiovascular Interventions 55, 303 (2002)   DOI   ScienceOn
15 S. Muhl and J. M. Mendez, Diamond and Related Materials 8, 1809 (1999)   DOI   ScienceOn
16 I. Tsyganov, M. F. Maitz, E. Wieser, E. Richter, and H. Reuther, Surface and Coatings Technology (2005)
17 H. T. Spijker, R. Graaff, P. W. Boonstra, H. J. Busscher, and W. van Oeveren, Biomaterials 24, 4717 (2003)   DOI   ScienceOn
18 F. Z. Cui and D. J. Li, Surface and Coatings Technology 99, 577 (2000)
19 Y. H. Kim, D. K. Han, K. D. Park, and S. H. Kim, Biomaterials 24, 2213 (2003)   DOI   ScienceOn
20 F. Zhang, X. Liu, Y. Mao, N. Huang, Y. Chen, Z. Zheng, Z. Zhou, A. Chen, and Z. Jiang, Surface and Coatings Technology 103-104, 136 (1998)
21 J. S. Cho, Y. W. Beag, S. Han, K. H. Kim, J. Cho, and S. K. Koh, surface and Coatings Technology 128-129, 66 (2000)