• Title/Summary/Keyword: 한상묵

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The Pro and Post Effects of Soshiho-tang on Rat's Liver Damage induced by $CCl_4$ (소자호탕이 $CCl_4$로 유발된 Rat의 간 장해 전후에 미치는 영향)

  • Dang Chung Woon;Han Kyung Hee;Han Sang Mook;Kim Myung Dong
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.18 no.5
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    • pp.1362-1373
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    • 2004
  • In studying the specific effects of some drugs, animals under experiments get some stress through laboratory environments, drug injection, and adaptation period. These stimuli do harms on liver function. Nowadays studies on liver intoxication and its protection are under research, but the function of dissolution is rarely under studies. It is widely accepted that Soshiho-tang has function of clearing away low spirits, and that it enables liver bloods to move stronger, and to have calm mind. So I injured rats liver by injectioning CCI₄. And the rats took in Soshiho-tang solution. I made a comparison between the functions before and after rat's liver damage. There are many representative serums used to note an index on liver damage. I used total protein, albumin, ALP, GOT, GPT activity, P450, SOD, Catalase, GST, GR, and GPx. I got the following results. When Soshiho-tang was injected after CCI4 intoxication, total protein and albumin decreased. When Soshiho-tang was injected, ALP decreased, compared with control group. When Soshiho-tang was injected after CCI₄ intoxication, AST and ALT decreased. When Soshiho-tang was injected before CCI₄ intoxication, P450 was restrained. When Soshiho-tang was injected, LPO was all restrained. When Soshiho-tang was injected, SOD, Catalase, GST, GR, and, GPx increased. These results show that blood test reveals that it is good to inject Soshiho-tang after CCI₄ intoxication, but that it is good to inject Soshiho-tang before CCI₄ intoxication in case of P450, LPO, SOD, Catalase, GST, GR, and GPx. It is estimated that the medication period and time of liver damage by CCI₄ have counter results, and that it needs more modified study.

Structural Damping Ratio of Steel Plate Concrete(SC) Shear Wall at the Low Stress Level Identified by Vibration Test (진동시험을 통한 강판콘크리트(SC) 전단벽의 저응력수준에서의 구조 감쇠비 규명)

  • Cho, Sung Gook;So, Gihwan;Kim, Doo Kie;Han, Sang Mook
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.35 no.2
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    • pp.255-264
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    • 2015
  • Steel plate concrete (SC) structure has been developed as a new structural type. Rational damping value shall be determined for the seismic design of SC structure. This study evaluated damping ratio of SC structure through experiments. For the study, a SC shear wall specimen was constructed and dynamically tested on the shaking table. Acceleration time history responses measured from testing were converted to the transfer functions and analyzed by using experimental modal analysis technique. The structural damping ratio of the specimen was identified as 4% to critical. Considering the shaking table test was performed at the excitation level corresponding to the low stress level of the specimen, 4% could be suggested as a structural damping for design of SC structure for operating basis earthquake.

Effect of Combined Acupuncture at Hefu(LI4), Taichong(LR3) and Moxibustion at Shangwan(CV13), Zhongwan(CV12), Xiawan(CV10) on the Serum Gastrin Level in Rats (상완, 중완, 하완 구요법과 사관 침요법의 혼합사용이 정상 백서 위 기능에 미치는 영향)

  • Han Sang-Muk;Hwang Tae-Jun;Kim Hong-Jae;Jung Sang-Gu;Jo Seung-Mook;Yu Yun-Cho;Kim Meyong-Dong
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.19 no.5
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    • pp.1238-1242
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    • 2005
  • Shangwan(CV13), Zhongwan(CV12), Xiawan(CV10), Hefu(L14) and Taichong(LR3) which belong to Conception Vessel and stomach meridian are acupuncture points frequently used for healing gastrointestinal desease in oriental medicine. The present study was conducted to see the effects produced by combined acupuncture(A), electro-acupuncture(EA) and moxibustion using five acupoints which belongs to different meridians on serum gastrin level in rats. Electro-acupuncture (2 Hz, intensity; 10 times muscle twitch threshold) was applied for 30 minutes to Hefu(LI4), Taichong(LR3) under halothane anesthesia. Moxibustion ($1.6{\pm}0.3\;mg$, 5 times of a day) was applied during 3 days to CV10, CV12, CV13 under halothane anesthesia. Combined stimuli of acupuncture at Hefu(LI4), Taichong(LR3) and moxibustion at CV13, CV12 increased serum gastrin level significantly eventough combined simulus of moxibustion on CV 10 was not shown any change. And combined stimul of EA and moxibustion at experimental all groups were not shown any effects. These data suggest that effects of acupuncture and moxibustion are depentent with used acupoints and combination stimuli method.

Analysis of the Reinforced I section UHPCC (Ulrea High Performance Cementitous Composites) beam without stirrup (전단철근이 없는 I형 휨보강 UHPCC 보의 거동해석)

  • Kim Sung Wook;Han Sang Muk;Kang Su Tae;Kong Jeong Shick;Kang Jun Hyung;Jun Sang Eun
    • Proceedings of the Korea Concrete Institute Conference
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    • 2004.11a
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    • pp.409-412
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    • 2004
  • Over last decade extensive researches have been undertaken on the strength behaviour of Fiber Reinforced Concrete(FRC) structures. But the use of Ultra-High Strength Steel Fiber Cementitious Concrete Composites is in its infancy and there is a few experiments, analysis method and design criteria on the structural elements constructed with this new generation material which compressive strength is over 150 MPa and characteristic behaviour on the failure status is ductile. The objective of this paper is to investigate and analyze the behaviour of reinforced rectangular structural members constructed with ultra high performance cementitious composites (UHPCC). This material is known as reactive powder concrete (RPC) mixed with domestic materials and its compressive strength is over 150MP. The variables of test specimens were shear span ratio, reinforcement ratio and fiber quantity. Even if there were no shear stirrups in test specimens, most influential variable to determine the failure mode between shear and flexural action was proved to be shear span ratio. The characteristics of ultra high-strength concrete is basically brittle, but due to the steel fiber reinforcement behaviour of this structure member became ductile after the peak load. As a result of the test, the stress block of compressive zone could be defined. The proposed analytical calculation of internal force capacity based by plastic analysis gave a good prediction for the shear and flexural strength of specimens. The numerical verification of the finite element model which constitutive law developed for Mode I fracture of fiber reinforced concrete correctly captured the overall behaviour of the specimens tested.

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Properties of Ultra High Performance Fiber Reinforced Cementitious Composites Mixed with Limestone Powder (석회석 미분말을 혼입한 초고성능 섬유보강 시멘트복합재의 특성)

  • Han, Sang-Mook;Wu, Xiang-Guo
    • Journal of the Korean Society of Hazard Mitigation
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    • v.8 no.2
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    • pp.23-30
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    • 2008
  • UHPC has high performance, high strength and excellent mechanical properties. Moreover UHPC(Ultra High Performance Cementitious Composite) has advantage to reduce cross section under the same load compared with other kinds of concrete. But silica fume which is imported from foreign country has a abundant portion in UHPC mixture in comparison with normal concrete. This is one of the main reason to raise the construction cost. Superior mechanical properties of UHPC due to the optimum filling composition can be changed by replacing the very fine ingredient. The purpose of this research is to grasp the characteristic of UHPC which silica fume and silica flour is replaced with limestone powder. This experiment can be divided into three classes according to the kinds of replacement. The compressive strength and flow of all types were measured and microstructure and hydration phenomena for comparing RPC were analyzed by SEM, XRD, NMR method. As a result, the replacement can be considered to be effective by for the decrease of the UHPC structure construction cost and improvement of the fresh UHPC.

The Moment-Curvature Relationship of the Rectangular Ultra High Performance Fiber Reinforced Concrete Beam (초고강도 섬유보강 직사각형 콘크리트보의 모멘트-곡률 관계)

  • Han, Sang-Mook;Guo, Qing-Yong
    • Journal of the Korean Society of Hazard Mitigation
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    • v.11 no.3
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    • pp.9-15
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    • 2011
  • The flexural behavior of the UHPFRC rectangular beam which has 100 MPa, 140 MPa compressive strength were compared with that of the typical RPC rectangular beam which has same geometrical shape, prestressd force and 160 MPa compressive strength. UHPFRC beam was not reinforced at all and the variable of test is fraction of steel fiber, compressive strength of concrete, method of prestressing and ratio of prestressing bar. The behavior of UHPFRC beam was analysed by relationship of moment - curvature and load - deflection. Simple modeling of stress-strain of UHPFRC was proposed. Based on the proposed constituted, the flexural moment-curvature relationship was calculated and compared with experimental data on prestressed UHPFRC beams. Good agreement between calculated strengths and experimental data is obtained.

Finite Element Analysis of Ultra High Performance Fiber Reinforced Concrete 50M Composite Box Girder (초고강도 섬유보강 콘크리트 50M 합성 박스거더의 유한요소해석)

  • Makhbal, Tsas-Orgilmaa;Kim, Do-Hyun;Han, Sang-Mook
    • Journal of the Korean Recycled Construction Resources Institute
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    • v.6 no.2
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    • pp.100-107
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    • 2018
  • The material and geometrical nonlinear finite elment analysis of UHPFRC 50M composite box girder was carried out. Constitute law in tension and compressive region of UHPFRC and HPC were modeled based on specimen test. The accuracy of nonlinear FEM analysis was verified by the experimental result of UHPFRC 50M composite girder. The UHPFRC 50M segmental composite box girder which has 1.5% steel fiber of volume fraction, 135MPa compressive strength and 18MPa tensile strength was tested. The post-tensioned UHPFRC composite girder consisted of three segment UHPFRC U-girder and High Strength Concrete reinforced slab. The parts of UHPFRC girder were modeled by 8nodes hexahedron elements and reinforcement bars and tendons were built by 2nodes linear elements by Midas FEA software. The constitutive laws of concrete materials were selected Multi-linear model both of tension and compression function under total strain crack model, which was included in classifying of smeared crack model. The nonlinearity of reinforcement elements and tendon was simulated by Von Mises criteria. The nonlinear static analysis was applied by incremental-iteration method with convergence criteria of Newton-Raphson. The validation of numerical analysis was verified by comparison with experimental result and numerical analysis result of load-deflection response, neutral axis coordinate change, and cracking pattern of girder. The load-deflection response was fitted very well with comparison to the experimental result. The finite element analysis is seen to satisfactorily predict flexural behavioral responses of post-tensioned, reinforced UHPFRC composite box girder.

Ductile Behavior of Ultra High Performance Fiber Reinforced Concrete Segmental Box Girder (초고강도 섬유보강 콘크리트 분절형 박스거더의 연성 거동)

  • Jeong, Min-Seon;Park, Sung-Yong;Han, Sang-Mook
    • Journal of the Korean Recycled Construction Resources Institute
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    • v.5 no.3
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    • pp.282-289
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    • 2017
  • The flexural behavior tests of UHPC segmental Box girder which has 160MPa compressive strength and 15.4m length were carried out. The test variables are area of prestressing wires, volume fraction of steel fibers and longitudinal reinforcing bars in upper flange and web. PS tendons which has 32 strands of 15.2mm diameter in lower flange, 24 strands and 14 strands in lower flange were arranged and volume fraction of 2%, 1.5% and 1.0% is used in box girder concrete. UHPFRC box girder which has 32 strands in lower flange showed the over reinforcement and brittle behavior. UHPFRC box girder which has 24 strands showed the similar peak load as 32 strands girder and ductile behavior as large deflection. UHPFRC box girder which has 14 strands showed half of the peak load of 24 strands box girder and ductile behavior. After the application of the formular for the reinforcement index to the behavior of the UHPFRC box girders, reinforcement index does not determine the characteristic of behavior of UHPFRC box girder exactly. So the index should consider the dimension precisely and modify the reference value corresponding to the 0.005 strain of the prestressing strands.

Flexural Behavior of Segmental U-Girder and Composite U-Girder Using Ultra High Performance Concrete (초고강도 섬유보강 콘크리트를 사용한 분절형 U거더 및 합성 U거더의 휨거동)

  • Lee, Seung-Jae;Makhbal, Tsas-Orgilmaa;Kim, Sung-Tae;Han, Sang-Mook
    • Journal of the Korean Recycled Construction Resources Institute
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    • v.5 no.3
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    • pp.290-297
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    • 2017
  • The flexural behavior tests of UHPC segmental U-girder and composite U-girder which has 160MPa compressive strength and 15.4m length were carried out. The test variables are volume fraction of steel fibers and slab over the U-girder. Each U-girder has longitudinal re-bars in web and lower flange. PS tendons which has 2 of 15.2mm diameter in upper flange and PS tendons which has 7 of 15.2mm diameter in lower flange were arranged and prestressed at onetime in U-girder connection stage. Enough strong prestressing force which applied to U-girder due to ultra high performance concrete strength can withstand the self weight and dead load in U-girder stage. By comparison with the brittle behavior of U-girder, composite U-girder showed the stable and ductile behavior. After the construction of slab over U-girder, flexural load capacity of composite U-girder can bear the design load in final construction stage with only one time prestressing operation which already carried out in U-girder stage. This simple prestressing method due to the ultra high strength concrete have the advantage in construction step and cost. The shear key which has narrow space has the strong composite connection between ultra high strength concrete U-girder and high strength concrete slab didn't show any slip and opening right before failure load.

The Ductile Behavior Test of Ultra High Performance Fiber Reinforced Concrete Rectangular Beam by the Combination of the Fiber and Group of Reinforcing Bars (강섬유와 철근집합체 조합에 의한 초고강도 섬유보강 콘크리트 직사각형보의 연성거동에 대한 실험)

  • Han, Sang-Mook;An, Jin-Woo
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.19 no.3
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    • pp.139-148
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    • 2015
  • The purpose of this paper is to induce the ductile behavior of the UHPFRC member after the peak load by using the bundle of longitudinal reinforcing bar as a substitute for steel fiber. Experiments on the flexural behavior of the Ultra High Performance Concrete rectangular beam with the combination of the steel fiber and longitudinal reinforcing bar were carried out. The volume fractions of steel fiber are 0%, 0.7%, 1%, 1.5%, 2% and the reinforcement ratios of longitudinal reinforcing bar which induce the ductile behavior are 0.0036, 0.016, 0.028 and 0.036. 15 UHPC beams were made with the combination of these test factors. Not only steel fiber but also bundle of longitudinal reinforcing bar has the effect to induce ductile behavior of UHPC structural member. The combination of 0.7% volume fraction of steel fiber and 0.028 reinforcement ratio showed the most economic combination. The relationship of load-deflection, strain variation of the concrete and the crack pattern indicate the usefulness of the bundle of the longitudinal bar which has small diameter with close arrangement each other.