• Title/Summary/Keyword: 하이브리드 법

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Preparation and Characterization of PLGA Scaffold Impregnated Keratin for Tissue Engineering Application (케라틴이 함유된 조직공학적 PLGA 지지체의 제조 및 특성 분석)

  • Oh, A-Young;Kim, Soon-Hee;Lee, Sang-Jin;Yoo, James J.;Dyke, Mark van;Rhee, John M.;Khang, Gil-Son
    • Polymer(Korea)
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    • v.32 no.5
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    • pp.403-408
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    • 2008
  • Keratin is the major structural fibrous protein providing outer covering such as wool, hair, and nail. Keratin is useful as natural protein. We developed the keratin loaded poly(L-lactide-co-glycolide) (PLGA) scaffolds (keratin/PLGA) for the possibility of the application of the tissue engineering using bone marrow mesenchymal (BMSCs). Keratin/PLGA (contents 0%, 10%, 20% and 50% of PLGA weight) scaffolds were prepared by solvent casting/salt leaching method. We characterized porosity, wettability, and water uptake ability, DSC of keratin/PLGA scaffold. We seeded BMSCs isolated from the femurs of rat into the inner core of the hybrid scaffold. Celluar viability were assayed by 3- (4,5-dimethylthiazol-2-yl) -2,5-diphenyl-tetrazolium bromide (MTT) test. We confirmed that keratin/PLGA scaffold is hydrophilic by wettability, and water uptake ability measurement results. In MTT assay results, cell viability in scaffolds impregnated 10 and 20 wt% of keratin were higher than other scaffolds. In conclusion, we suggest that keratin/PLGA scaffold may be useful to tissue engineering using BMSCs.

Convergence Comparison of Linear Oscillating Electric Machines (리니어 오실레이팅 전기기기의 비교 연구)

  • Jeong, Sung-In;Eom, Sang In
    • Journal of the Korea Convergence Society
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    • v.12 no.12
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    • pp.273-280
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    • 2021
  • This paper presents the results of study of linear oscillating electric machine; Cartesian, cylindrical type with permanent magnet, flux reversal, cylindrical reluctance, and transverse flux type. The focus of the work is the suggestion of the characteristics and design process of propose topology, respectively. First of all, there are five types of the proposed to this study on the basis of the existing literatures; Cartesian type, cylindrical type, flux reversal type, cylindrical reluctance type, and transverse flux type. All topology is achieved using equivalent magnetic circuit considering leakage elements as initial modeling. Cartesian type is investigated by number of phases and number of pole pairs using optimal process. A cylindrical type is described by number of phases and displacement of stroke. The flux reversal type is proposed based on the symmetrical and non symmetrical stator cores of the surface mounted PMs mover, and non slanted PMs and slanted PMs of the flux concentrating PMs mover. A cylindrical reluctance type is studied by the shape of mover teeth in geometric aspect to reduce force ripple and increase magnetic flux. A transverse flux type is considered by dividing the transverse flux electric excited and the transverse flux permanent magnet excited. It is significant that the study gives a design rules and features of linear oscillating electric machine.

Effect of Micro-bolt Reinforcement for Composite Scarf Joint (복합재 스카프 조인트에서의 마이크로 볼트 보강에 대한 타당성 연구)

  • Lee, Gwang-Eun;Sung, Jung-Won;Kweon, Jin-Hwe
    • Composites Research
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    • v.32 no.1
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    • pp.37-44
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    • 2019
  • The reinforcement effect of micro-bolt for a bonded scarf joint was investigated. Three scarf ratios of 1/10, 1/20, and 1/30 were considered to examine the effect of scarf patch configuration on joint strength. To maintain the same density of micro-bolt, 16, 32, and 48 bolts were installed in the scarf joint specimens with scarf ratios of 1/10, 1/20, and 1/30, respectively. Tests were also carried out on the joints that are bonded with only adhesive and that are fastened with only micro-bolts to obtain reference values. The average failure loads of the adhesive joints with scarf ratios of 1/10, 1/20, and 1/30 were 29.7, 39.6, and 44.8 kN, respectively. In case of micro-bolt reinforcement, the failure loads at the same scarf ratios were 28.4, 37.2, and 40.1 kN, respectively, which corresponds to 96, 94, and 90% of the pure adhesive joint failure loads. In the case of using only micro-bolts, the failure loads were only 13-25% of the average failure loads of pure adhesive joints. Fatigue test was also conducted for the joints with scarf ratio of 1/10. The results show that the fatigue strength of hybrid joints using both adhesive and microbolts together slightly increased compared to the fatigue strength of adhesive joint, but the rate of increase was small to 2-3%. Through this study, it was confirmed that the reinforcement effect of micro-bolt is negligible in the scarf joints where shear stress is dominating the failure, unlike in the structure where peel stress is dominant.

Low Cycle Fatigue Life Behavior of GFRP Coated Aluminum Plates According to Layup Number (적층수에 따른 GFRP 피막 Al 평활재의 저주기 피로수명 평가)

  • Myung, Nohjun;Seo, Jihye;Lee, Eunkyun;Choi, Nak-Sam
    • Composites Research
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    • v.31 no.6
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    • pp.332-339
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    • 2018
  • Fiber metal hybrid laminate (FML) can be used as an economic material with superior mechanical properties and light weight than conventional metal by bonding of metal and FRP. However, there are disadvantages that it is difficult to predict fracture behavior because of the large difference in properties depending on the type of fiber and lamination conditions. In this paper, we study the failure behavior of hybrid materials with laminated glass fiber reinforced plastics (GFRP, GEP118, woven type) in Al6061-T6 alloy. The Al alloys were coated with GFRP 1, 3, and 5 layers, and fracture behavior was analyzed by using a static test and a low cycle fatigue test. In the low cycle fatigue test, strain - life analysis and the total strain energy density method were used to analyze and predict the fatigue life. The Al alloy did not have tensile properties strengthening effect due to the GFRP coating. The fatigue hysteresis geometry followed the behavior of the Al alloy, the base material, regardless of the GFRP coating and number of coatings. As a result of the low cycle fatigue test, the fatigue strength was increased by the coating of GFRP, but it did not increase proportionally with the number of GFRP layers.

A Study on the Effects of Intrinsic Motivation, Extrinsic Motivation and Pre-knowledge of Office Workers on the Hybrid Start-up Intention (직장인의 내재적 동기, 외재적 동기와 사전지식이 Hybrid 창업의도에 미치는 영향 연구)

  • Yun, Kyung-Ho;You, Yen-Yoo;Park, In-Chae;Park, Hyun-Sung
    • Journal of Convergence for Information Technology
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    • v.11 no.6
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    • pp.83-98
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    • 2021
  • This study identified the influence of employees' hybrid start-up intention (intention to start a business while maintaining a job) on the employees' self-determination motivation (intrinsic motivation, extrinsic motivation) and prior knowledge through the Model of Goal-directed Behavior (MGB). We used a PLS-SEM called SmartPLS 3.0 for 126 valid samples collected by judgement extraction for office workers throughout June 13, 2020 to July 3, 2020, and empirically evaluated the measurement model (internal consistency reliability, convergent and discriminant validity) and the structural model (multicollinearity, determination coefficient, effect size, predictive relevance, etc.). Only the intrinsic motivation for realizing the hybrid start-up goal of office workers had a significant impact on the hybrid start-up attitude and subjective norms, and the prior knowledge of hybrid start-up had a significant impact on the hybrid start-up desire and the hybrid start-up intention. In order to induce hybrid start-ups for workers with unstable employment, we need systems and programs that can inspire employees with intrinsic motivation and knowledge about hybrid start-up, so follow-up researches are necessary to analyze about government systems and consulting support that can promote hybrid start-up.

Removal of NOx from Graphene based Photocatalyst Ceramic Filter (그래핀 기반 광촉매 담지 세라믹필터에서 질소산화물(NOx)의 제거)

  • Kim, Yong-Seok;Kim, Young-Ho
    • Applied Chemistry for Engineering
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    • v.33 no.6
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    • pp.600-605
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    • 2022
  • In this study, nitrogen oxide (NOx) removal experiments were performed using a graphene based ceramic filter coated with a V2O5-WO3-TiO2 catalyst. Graphene oxide (GO) was prepared by Hummer's method using graphite, and the reduced graphene oxide was produced by reducing with hydrazine (N2H4). Vanadium (V), Tungsten (W), and Titanium (Ti) were coated by the sol-gel method, and then a metal oxide-supported filter was prepared through a calcination process at 350 ℃. A NOx removal efficiency test was performed for the catalytic ceramic filters with UV light in a humid condition. When graphene oxide (GO) and reduced graphene oxide (rGO) were present on the filter, the NOx removal efficiency was superior to that of the conventional ceramic filter. Most likely, this is due to an improvement in the adsorption properties of NOx molecules on graphene coated surfaces. As the concentration of graphene increased, higher NOx removal efficiency was confirmed.

An Exploratory Study on Organizational Smart Learning Success from an HRD Perspective (HRD 관점에서 기업의 스마트 러닝 성공을 위한 탐색적 연구)

  • Yeseul Oh;Jaeyoung An;Haejung Yun
    • Knowledge Management Research
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    • v.24 no.4
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    • pp.219-235
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    • 2023
  • The advancement of digital technology and the impact of COVID-19 have brought about changes in corporate innovation and organizational culture, thereby highlighting the significance of Smart Learning in the field of HRD (Human Resource Development). This trend has led to an increased interest in personalized Smart Learning among employees due to the growth of hybrid work and the widespread adoption of smart work practices. This study aimed to illuminate the relative importance of the factors that constitute Smart Learning from the perspective of HRD practitioners. Through a review of prior literature, Smart Learning hierarchy and factors most fitting to the current context were identified, and their relative importance was determined using the AHP method. Consequently, in the first-tier factors, importance was confirmed in the order of 'Learning Activities', 'Teaching Activities', 'Learning Content', 'Assessment and Evaluations', and 'Learning Time and Space'. At the second-tier encompassing all factors, 'Pedagogical Strategy', 'Learning Results', 'Learning Tasks', 'Learning Goal', and 'Learning Support' emerged within the top five factors. These findings are significant in that they redefine the concept of smart learning and propose an academic framework for future research. Additionally, from a practical perspective, it is anticipated that this study will contribute valuable insights for HRD practitioners, aiding them in focusing on which factors to prioritize for enhancing and advancing Smart Learning initiatives.

High Strength Slaughter Wastewater Treatment in a Novel Combined System of Hybrid-Rotating Biological Contactor and Biological Aerated Filter (Hybrid-RBC와 BAF의 조합공정을 이용한 고농도 도축폐수의 처리 특성)

  • Jung, Chan-Il;Ahn, Jo-Hwan;Bae, Woo-Keun;Kim, Seung-Jin
    • Journal of Korean Society of Environmental Engineers
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    • v.33 no.2
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    • pp.77-84
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    • 2011
  • This study was conducted to develop a novel combined system of a hybrid rotating biological contactor (RBC) process that was composed of an attached- and suspended- biomass reactor, followed by a settler and a biological aerated filter (BAF) column to treat a high strength slaughter wastewater. Long term influences of organic and nitrogen loading rates were investigated to see how the combined system worked in terms of the removal efficiency. A synthetic wastewater containing a pork cutlet steak source (commercially available) and swine blood was used to feed the combined system. The hybrid RBC process showed excellent removals: about 95% for soluble COD and 85% for ammonium nitrogen. However, the unsettled solids seriously deteriorated the removal efficiency of total COD (TCOD) and total nitrogen (TN) in the RBC process. A significant fraction of the TCOD and suspended solids (SS) was further removed in the BAF column although the effluent quality was still unsatisfactory, giving TCOD 300 mg/L, SS 180 mg/L and TN 59 mg/L. An addition of polyaluminium chloride into the RBC effluent improved the performance of the settler and BAF, producing an excellent quality of final effluent; TCOD 16.5 mg/L, SS 0 mg/L, TN 55.5 mg/L, TP 1.3 mg/L. Therefore, it was confirmed that the combined system of hybrid RBC and BAF could treat a high strength slaughter wastewater excellently.

A Study on Public Interest-based Technology Valuation Models in Water Resources Field (수자원 분야 공익형 기술가치평가 시스템에 대한 연구)

  • Ryu, Seung-Mi;Sung, Tae-Eung
    • Journal of Intelligence and Information Systems
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    • v.24 no.3
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    • pp.177-198
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    • 2018
  • Recently, as economic property it has become necessary to acquire and utilize the framework for water resource measurement and performance management as the property of water resources changes to hold "public property". To date, the evaluation of water technology has been carried out by feasibility study analysis or technology assessment based on net present value (NPV) or benefit-to-cost (B/C) effect, however it is not yet systemized in terms of valuation models to objectively assess an economic value of technology-based business to receive diffusion and feedback of research outcomes. Therefore, K-water (known as a government-supported public company in Korea) company feels the necessity to establish a technology valuation framework suitable for technical characteristics of water resources fields in charge and verify an exemplified case applied to the technology. The K-water evaluation technology applied to this study, as a public interest goods, can be used as a tool to measure the value and achievement contributed to society and to manage them. Therefore, by calculating the value in which the subject technology contributed to the entire society as a public resource, we make use of it as a basis information for the advertising medium of performance on the influence effect of the benefits or the necessity of cost input, and then secure the legitimacy for large-scale R&D cost input in terms of the characteristics of public technology. Hence, K-water company, one of the public corporation in Korea which deals with public goods of 'water resources', will be able to establish a commercialization strategy for business operation and prepare for a basis for the performance calculation of input R&D cost. In this study, K-water has developed a web-based technology valuation model for public interest type water resources based on the technology evaluation system that is suitable for the characteristics of a technology in water resources fields. In particular, by utilizing the evaluation methodology of the Institute of Advanced Industrial Science and Technology (AIST) in Japan to match the expense items to the expense accounts based on the related benefit items, we proposed the so-called 'K-water's proprietary model' which involves the 'cost-benefit' approach and the FCF (Free Cash Flow), and ultimately led to build a pipeline on the K-water research performance management system and then verify the practical case of a technology related to "desalination". We analyze the embedded design logic and evaluation process of web-based valuation system that reflects characteristics of water resources technology, reference information and database(D/B)-associated logic for each model to calculate public interest-based and profit-based technology values in technology integrated management system. We review the hybrid evaluation module that reflects the quantitative index of the qualitative evaluation indices reflecting the unique characteristics of water resources and the visualized user-interface (UI) of the actual web-based evaluation, which both are appended for calculating the business value based on financial data to the existing web-based technology valuation systems in other fields. K-water's technology valuation model is evaluated by distinguishing between public-interest type and profitable-type water technology. First, evaluation modules in profit-type technology valuation model are designed based on 'profitability of technology'. For example, the technology inventory K-water holds has a number of profit-oriented technologies such as water treatment membranes. On the other hand, the public interest-type technology valuation is designed to evaluate the public-interest oriented technology such as the dam, which reflects the characteristics of public benefits and costs. In order to examine the appropriateness of the cost-benefit based public utility valuation model (i.e. K-water specific technology valuation model) presented in this study, we applied to practical cases from calculation of benefit-to-cost analysis on water resource technology with 20 years of lifetime. In future we will additionally conduct verifying the K-water public utility-based valuation model by each business model which reflects various business environmental characteristics.

Effect of 2-D DBP/PLGA Hybrid Films on Attachment and Proliferation of Intervertebral Disc Cells (2차원적 DBP/PLGA 하이브리드 필름이 디스크 세포의 부착과 증식에 미치는 영향)

  • Ko, Youn-Kyung;Jeong, Jae-Soo;Kim, Soon-Hee;Lim, Ji-Ye;Rhee, John-M.;Kim, Moon-Suk;Lee, Hai-Bang;Khang, Gil-Son
    • Polymer(Korea)
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    • v.32 no.2
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    • pp.109-115
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    • 2008
  • Because demineralized bone particle (DBP) contains various bioactive molecules such as cytokines, it is widely used biomaterials in the field of tissue engineering. In this study, we investigated the effect of 2-dimensional DBP/PLGA hybrid films on adhesion, proliferation and phenotype maintenance of intervertebral disc cells. PLGA films incorporated with different amount (0, 10, 20, 40 and 80 wt%) of DBP were prepared by the solvent evaporation method and characterized by scanning election microscopy (SEM). PLGA film has a flat and smooth surface. According to the increase of content of DBP, the surface of DBP/PLGA film exhibited few agglomerates and increased the roughness of the surface. Annulus fibrosus (AF) and nucleus pulposus (NP) cells were cultured on PLGA and DBP/PLGA film surface, and then examined the cell adhesion and proliferation by the cell count and SEM observation. The result of cell count and SEM observation revealed that 10 and 20% DBP in DBP/PLGA films were superior to adhesion and proliferation of both AF and NP cells. We confirmed that specific gene expression of disc cells on DBP/PLGA film based on the cell count result. Disc cells seeded on 20% DBP/PLGA film expressed the gene of type I and II collagen continuously. Therefore, pertinent content of biomaterials could provide more appropriate condition on adhesion and proliferation of cell. And this results may be used as a basic data for the intervertebral disc regeneration using tissue engineering.