• Journal of Life Science
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• v.28 no.10
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• pp.1186-1192
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• 2018

The purpose of this study was to compare the effects of either aerobic exercise or polyphenols supplementation on mRNA expression of endoplasmic reticulum stress in skeletal muscle of high fat diet-induced obese mice. In the study, mice were divided into five groups: (1) NC (normal diet for 16 weeks as a control, n=10), (2) HC (high fat diet for 16 weeks as a control, n=10), (3) H-Re (high fat diet with resveratrol 25 mg/kg supplementation for 16 weeks, n=10), (4) H-Ch (high fat diet with chrysin 50 mg/kg supplementation for 16 weeks, n=10), and (5) HE (high fat diet with aerobic exercise for 16 weeks, n=10). Aerobic exercise was performed on a treadmill for 40~60 min/day at 10~14 m/min, 0% grade, four days/week for 16 weeks. Endoplasmic reticulum stress related genes were measured by real-time polymerase chain reaction. ATF6, PERK, $IRE1{\alpha}$, and BIP/GRP78 mRNA were significantly decreased in HE compared with those in HC (p<0.05). Also, ATF6, $IRE1{\alpha}$, and BIP/GRP78 mRNA were significantly decreased in H-Re compared with those in HC (p<0.05). ATF6 mRNA was significantly decreased in H-Ch compared with that in HC (p<0.05). These findings suggest that aerobic exercise, resveratrol, and chrysin supplementation changed ER stress markers. However, aerobic exercise was most effective on ameliorating the high fat diet induced ER stress markers. Thus, it seems that aerobic exercise might have a more positive effect on skeletal muscle endoplasmic reticulum stress compared with polyphenol supplementation in high fat diet-induced obese mice.

• Archives of design research
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• v.19 no.5 s.67
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• pp.129-138
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• 2006

It is expected that the typical lifestyle of the future will be transformed into an opulent and comfortable existence as the quality of life improves due to the increase in household income and reduction in working hours. In the meantime, as the standard of living becomes increasingly more comfortable and plentiful, the toll on physical health becomes magnified as a result of obesity and insufficient exercise caused by super nutrition and change in labor conditions (from physical labor to mental labor). This has instigated a deep awareness in fitness on the part of many people, forcing them to recognize the significance of daily exercise and physical activity. The high annual growth rate in the fitness and athletic apparatus market, which is more than 20%, is attributed to this phenomenon. The Elliptical Cross Trainer(ECT), which has drawn wide attention recently, is a non-impact athletic apparatus that not only promotes exercise of the upper body parts in such sports as skiing but also the exercise of lower parts of the body on a treadmill. It is a type of cross training athletic gear that has been developed for aerobic exercise throughout the entire body. It has already formed a market as big as that of the treadmill in Europe, America, etc. Recently, its demand is growing sharply in the Korean markets as well as those in Northeast Asian countries, Despite such demand increase and expansion, since most of the expensive ECTs are exclusively supplied by suppliers in only a few advanced countries, localization of the ECT is urgently required in order to enhance competitiveness of Korean manufacturers and to expand the market. This paper introduces the process and results of a design-engineering cooperative study that was peformed for the development of the ECT.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.10
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• pp.480-489
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• 2017

Blood flow restriction(BFR) exercise is defined as low intensity and short term exercise using pneumatic pressure belts at the top of limbs, which affects the physiological functions of the body. The purpose of this study was to investigate the effects of walking exercise with BFR on inflammatory index, isokinetic muscle function, and thigh circumference in obese women. Eleven obese women(> BMI $25kg/m^2$ & > body fat 30%) wore pneumatic pressure belts on both femurs and performed walking exercise twice per day, 3 days/wk for 4 weeks (walking 2 min; resting 1 min). Data analysis was carried out using paired t-test. Body weight, BMI, and body fat significantly decreased after exercise(p<.05), and right thigh circumference significantly decreased(p<.05). The concentration of plasma IL-6 significantly increased(p<.05) after exercise. TNF-${\alpha}$ level was not statistically different but tended to slightly increase. CRP slightly decreased, although it did not reach statistical significance after exercise. Muscle strength significantly increased in the $60^{\circ}/sec$ of right/left side extension, left side flexion, and $180^{\circ}/sec$ of left side extension after training(p<.05). These results suggest that 4 weeks of blood flow restriction walking exercise has positive effects on inflammatory index and isokinetic muscle function. Therefore, we consider that blood flow restriction exercise can be used for treatment of obesity, related chronic diseases, and metabolic syndrome. Further, blood flow restriction exercise for a short time has similar effects as a high intensity resistance program.

• Journal of Life Science
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• v.19 no.9
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• pp.1190-1199
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• 2009

The purpose of this study is to identify the effects of exercise training and oak tree wood vinegar ingestion on the blood lipids and antioxidant activities of rats. The subjects were 28 Sprague Dawley male rats, and they were assigned into four groups (n=7, respectively): the control group (CON), the exercise group (EXE), the vinegar ingestion group (VIN), and the vinegar ingestion and exercise training group (VINEXE). The diet was based on high fat and oral administration of oak tree wood vinegar. The rats that were not given oak tree wood vinegar were given the same amount of distilled water orally in order to maintain the same level of stress. They were exercise trained on motor-driven treadmills during a four-week session. Weight changes in the VINEXE were significantly inhibited in the later period of exercise, when compared to the CON (p<0.05). Fat increase was significantly suppressed in VIN and EXE (p<0.05), and a synergistic effect was discovered in the VINEXE (p<0.05). Glucose and ammonia levels were significantly reduced in the EXE, VIN, and VINEXE compared to the CON (p<0.05). In blood lipids, TC and LDL-C were significantly enhanced in the EXE, VIN, and VINEXE compared to the CON (p<0.05), while HDL-C was significantly improved in the EXE and VINEXE (p<0.05). Liver MDA contents showed significant changes in each group (p<0.05), and SOD activities were significantly enhanced in the VIN and the VINEXE when compared to other groups (p<0.05). Therefore, oak tree wood vinegar ingestion with exercise training for four weeks may result in inhibition of weight gain, improvement of blood lipids, and inhibition of lipid peroxidation, contributing to health promotion.

• Journal of rehabilitation welfare engineering & assistive technology
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• v.7 no.2
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• pp.101-107
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• 2013

In this paper, we were to investigate effect of correction to muscle imbalance in lower limbs according to reduction of weight bearing methods of four point of horizontal shaft using two-belt treadmill. Participants were divided to two group according to each ten peoples who have difference of muscle function in left and right legs over 20%. Experiment progressed forty minutes a day three days a week, total four weeks and we estimated the maximal peak torque and average power for testing joint torque in hip, knee and ankle. The results showed that the correction effect of muscle imbalance to the maximal muscle strength was the most effective in hip joint. Also in knee joint, correction effect of muscular reaction was the most effective too. We thought that reduction of weight bearing methods could be positive effect to correct muscle imbalance in lower limbs.

• Journal of Physiology & Pathology in Korean Medicine
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• v.22 no.4
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• pp.884-890
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• 2008

This study classified 40 of 10 weeks-old male Sprague Dawley rats which have osteoporosis caused by glucocorticoid(GC) induction into four groups of 10 rats and made the subjects medicated them Eucommia ulmoides Oliver and participate in treadmill exercise. Group I was non-treatment after GC induction; Group II was treadmill exercise after GC induction; Group III was Eucommia ulmoides Oliver feeding after GC induction; Group IV was treadmill exercise and Eucommia ulmoides Oliver feeding after GC induction. In the bone mineral density and bone strength test, there was a statistically significant difference between the group I, II, III compared to group IV(p<0.05). In the osteocalcin level as one of bone formation indexes, there was a statistically significant difference between the group I, II, III compared to group IV(p<0.05). In respect to the calcium there was a statistically significant difference between group I, II, III compared to group IV(p<0.05). In respect to histological findings, the group IV showed mild femur disruption and lytic change on femur section. The above results suggests that Eucommia ulmoides Oliver medicated and treadmill exercise is effective to prevention and treatment of osteoporosis.

• Journal of the Korean Society of Physical Medicine
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• v.3 no.2
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• pp.97-102
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• 2008

Purpose : The purpose of this study was to find the effect of foot bath on blood pressure(BP) following treadmill exercise. Methode : Subject of study were forty healthy males without any cardiovascular, musculoskeletal, and neurologic diseases. Following twenty minutes walking at a speed of 5m/s on the treadmill, ten twenty subjects in experimental group received foot bath, on the dominant lower limb while sitting in chair. Foot bath was applied to the level of the lateral and medial malleoli keeping the temperature of the paraffin bath at $40{\pm}0.5^{\circ}C$. Twenty subjects in control group took a rest sitting in chair in a comfortable position. BP was measured in right brachial artery. BP was measured five times(before exercise, immediately after exercise, 5 minutes, 10 minutes, and fifteen minutes after exercise). Results : The study showed that for diastolic blood pressure, there was no significant difference between the experimental and the control group. However, systolic blood pressure(SBP) increased significantly after exercise compared with SBP before exercise (p<.05). In addition, SBP in five minutes after exercise decreased significantly compared with SBP in immediately after exercise (p<.05). On the other hand, the control group had significant difference between SBP measured before exercise and SBP measured at the other measure time (p<.05). In five minutes after exercise, SBP in experimental group had significant difference with SBP in control group (p<.05). Similarly, in ten and fifteen minutes after exercise, SBP in experimental group had significantly difference with SBP in control group (p<.05). Conclusion : Consequently it was confirmed that when foot bath was applied, the increased BP induced by the exercise returned to normal range rapidly.

• PNF and Movement
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• v.15 no.3
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• pp.333-341
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• 2017

Purpose: This study was to explore the effects of trunk exercise using PNF combined with treadmill training on balance and walking ability in patients with Parkinson's disease. Methods: This study included 16 patients with Parkinson's disease. Participants were randomly assigned to 2 groups: an experimental group (n=8) and a control group (n=8). All participants underwent treadmill training for 30 minutes. In addition, the experimental group (trunk exercise using PNF) and control group (conventional training) participated in a 30-minute exercise program. Both groups performed the training 5 times per week for 4 weeks. Disease severity (determined using the unified Parkinson's disease rating scale motor subscale, UPDRS-3), balance (determined using the Berg balance scale, BBS), walking speed (determined using the 10-meter walking test, 10MWT), and walking endurance (determined using the 6-minute walking test, 6MWT) were measured at baseline and after 4 weeks. Results: Pre- to post-intervention improvement was noted on all outcome measures for both groups (p<0.05). Post-intervention, there was a significant improvement in the experimental group as compared to the control group for the following measured outcomes (p<0.05): UPDRS-3 (p=0.03; 95% CI, -5.52 to -0.24), BBS (p=0.04; 95% CI, 0.59 to 6.45), 10MWT (p=0.01; 95% CI, -2.19 to -0.42), and 6MWT (p=0.04; 95% CI, 1.81 to 96.72) Conclusion: The results of this study revealed that trunk exercise using PNF plus treadmill training improves balance and walking ability as compared to conventional training plus treadmill training in patients with Parkinson's disease.

• Journal of the Korean Society of Physical Medicine
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• v.8 no.1
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• pp.71-78
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• 2013

PURPOSE: The purpose of this study was to investigate the effects of treadmill exercise on blood components and antioxidant system in hyperlipidemic rats. METHODS: Three weeks old male rats were randomly assigned into General diet(GD, n=10), High fat Diet(HD, n=10), and High fat diet+Treadmill exercise(HDT, n=10) groups. Treadmill exercise consisted of the treadmill running 5 times per week during 6 weeks(30 min/time for first 3 weeks and 60 min/time the other 3 weeks). RESULTS: The levels of triglyceride and total cholesterol were increased in HD group compared with GD group, and recovered to level of GD group by treadmill exercise(p<.05). Plasma glucose and insulin concentrations were increased in HD group compared with GD group, and recovered to level of GD group by treadmill exercise(p<.05). Glutathione(GSH) and glutathione reductase(GRD) concentrations were decreased in HD group compared with GD group, and these decreases returned to the level of GD group by treadmill exercise(p<.05). Xanthine oxidase(XO) and malondialdehyyde (MDA) concentrations were increased in HD group compared with GD group, and these increases retuned to the level of GD group by treadmill exercise(p<.05). CONCLUSION: This study showed that treadmill exercise application were effective treatment strategy on hyperlipidemia. Therefore, it could be considered as a treatment method in the patients with hyperlipidemia disease. Treadmill exercise, Hyperlipidemia, Blood components.

• Physical Therapy Korea
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• v.11 no.2
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• pp.17-25
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• 2004

The purpose of this study was to assess the effect of applied insole types to lower extremities muscle fatigue during treadmill exercise. The control group and each different insole type group consisted of ten healthy male subjects. In the control group and each different insole type (soft type; 10 shore, semi-rigid type; 33 shore, rigid type; 50 shore) treadmill exercise was performed in twenty-five minutes. The electromyography (EMG) signals of four muscle (tibialis anterior, gastrocnemius medialis, rectus femoris, biceps femoris) were recording at sampling rate of 1024 Hz during treadmill exercise. The localized muscle fatigue (LMF) can be investigated using power spectral analysis. When did data analysis that excepted initial five minutes. The raw EMG signals was processed using the fast Fourier Transformation (FFT) and the median power frequency value was determined in initial ten second period and in last ten second period. Fatigue index was calculated and collected data were statistically analyzed by SPSS version 10.0 two-way using analysis of variance (ANOVA) with repeated measures ($4{\times}4$) was used to determine the main effect and interaction. Post hoc was performed with least significant difference. A level of significance was .05. Muscles fatigue index were significantly decreased in insole types (p<.05) and not significantly different in muscle (p>.05). Post hoc analysis shows that fatigue index in soft insole type, semi-rigid insole type and rigid insole type were lower than that control group (p=.028, p=.146, p=.095). There were no interaction between insole type and muscles (p>.05). The finding of this study can be used as a fundamental data when insole is applied and insole can be used to decreased of a fatigue during the dynamic exercise.