• The Korean Journal of Applied Statistics
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• v.12 no.1
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• pp.241-251
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• 1999

최근 약학계에서 동일한 활성 성분을 가지면서 용량만이 다른 제제의 개발이 증가되고 여러 개의 제제에 대한 생물학적 동등성 시험의 필요성이 대두됨에 따라, 중앙약심은 한 회사에서 개발된 제품으로서 동일한 활성 성분을 함유하고 용량만이 다른 두 가지 시험약에 대하에 동시에 시험을 행할 경우에 한하여 $3\times3$ 라틴방격법에 의한 생물학적 동등성 시험에 인정하기로 하였다. 이를 계기로 이영주 등(1998)은 온덴세트론 제제에 대한 생물학적 동등성 실험에서 $3\times3$ 라틴방격법을 적용하고 그 기준을 제시하고자 하였다. 본 논문에서는 이용주 등(1998)에 의해 제시된 기준에 대하여 통계적으로 재 고찰하고, 지존의 $2\times2$ 라틴방격법에 비해 상대적으로 길어진 총실험시간으로 인한 높은 결측치의 발생 가능성을 보완할 수 있는 3$\times$2 균형불완비블록계획법을 제시하고 분석방법과 적합성을 논의한다.

• The Korean Journal of Applied Statistics
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• v.24 no.4
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• pp.633-646
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• 2011

Clinical vaccines studies (that include cancer prevention vaccines and therapeutic vaccines) are ongoing to improve the quality of life and lengthen the human lifespan. Recently clinical trials and research on vaccines have become more active due to the prevalence of new viruses such as the A(H1N1) virus that freighted the whole word in 2009. In this paper we will describe the statistical aspects of clinical vaccine trials and outline the current situation of domestic and international vaccine development.

• Journal of the Korea Convergence Society
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• v.8 no.7
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• pp.93-99
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• 2017

Necessity of adjustment in level of difficulty of national examination for radiological technologists is being brought up. However, objective reasons are required to make those arguments more valid. Therefore in this research, result of national examination for radiological technologists under present system was analyzed in more convergence perspective via statistical analysis. This will provide basic data which is applicable when system of national examination for radiological technologists undergo improvements. For this, statistical analysis such as descriptive statistics and correlation analysis was conducted using SPSS program. Results are as follow. First, ratio of successful applicants for radiological technologists was highly fluctuant relative to other national examinations like doctor, nurse, physical therapist, etc. Second, level of difficulty and discernment of national examination for radiological technologists were differentiated from other examinations like doctor, nurse, physical therapist. Third, the 43th examination for radiological technologists conducted in 2015 had the highest discernment as 0.41, despite of lowest level of difficulty as 89.2, for radiologic applications. The results of this research is expected to be used as basic data when system of national examination for radiological technologists undergo improvements, in accordance with increased supplying plan of work-forces in medical radiological technologists.

• Journal of the Korean Geotechnical Society
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• v.21 no.3
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• pp.5-17
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• 2005

Spatial uncertainty of Busan marine clay ground, which commonly occurs during site investigation testing, data analysis and transformation modeling, has been described. In this paper geotechnical uncertainty of shear strength indicator $N_k$ has been quantified in both horizontal direction and vertical direction using geostatistical Kriging method. Most of soil data used are from 25 boring tests, 75 laboratory tests, 124 field vane tests and 25 cone penetration tests (CPT). CPT-$N_k$ data for undrained shear strength determination, which are the most important properties in geotechnical design stages, have been analysed. Comparison between cone factor from conventional CPT-based method and that of geostatistical method shows that geostatistical Kriging method is an ideal tool to quantify the spatial variability of uncertainty from self-correlation of soil property of interest, and can be recommended to identify the spatial distribution of consolidation .md shear strength of soils at any sites concerned.

• The Korean Journal of Applied Statistics
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• v.12 no.2
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• pp.621-631
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• 1999

재료의 피로 파괴과정은 균열의 발생과 전파 및 성장의 과정을 거쳐 마침내 결정적 균열의 크기가 일정한도를 넘어서면 재료의 파괴가 일어난다. 이 때까지의 시간, 즉 피로 수명이 역정규분포를 따를 때 재료의 수명과 스트레스 수준과 관계를 나타 내는 S-N곡선에 대한 대수선형모형(log-linear model)을 제시하고, 이 모형하에서 피로수명시험에 대한 통계적 최적시험설계방법을 찾는다. 통계적 최적여부에 대한 판단기준으로 설계 스트레스 수준하의 특정 시점에서의 신뢰도에 대한 최우추정량의 점근분산을 최소화하는 방법을 사용하였다.

• Proceedings of the Korean Geotechical Society Conference
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• 1995.10a
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• pp.25.1-33
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• 1995

지반공학 및 지반환경분야에서 문제의 관건은 표층과 흙의 성질에 대한 정보를 정확히 파악하는 것이다. 표층의 상황은 어느 현장이나 공간적으로 그 성질을 달리하므로 기술자의 경험이나 지구통계학을 이용하여 적절한 현장의 상태를 분석하게 된다. 휴스톤대학에 위치한 미국국립시험현장에서 수행한 28개의 콘관입시험을 통해 얻은 자료를 가지고 지구통계학적분석을 하여 비배수 전단강도의 3차원적 형태를 파악하였다. 본 연구를 통하여 지구통계학의 유용함과 현장의 변화가 상당함을 쉽게 이해하게 된다.

• Journal of the Korea institute for structural maintenance and inspection
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• v.25 no.6
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• pp.235-244
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• 2021

This study analyzes the applicability of limit state design method on bridge evaluation by considering the experiment of the existing bridge. The test strength of the member is obtained from the PSC beam bridge experiment. The test strength is compared with the calculated strength obtained from the statistical characteristics of material test strength and the two values are almost the same. The response modification factor and dynamic impact factor are obtained from the vehicle loading test. The rating factor is calculated by applying limit state design method as well as current evaluation method and the results are compared. The reliability index of the test bridge is calculated by using the statistical properties of the member strength obtained from material test and simulation. When the statistical properties of the PSC beam tested in this study are applied, the reliability index with a larger value was obtained than the reliability index obtained with the statistical properties of the design code.

• Journal of the Korean GEO-environmental Society
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• v.23 no.6
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• pp.19-23
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• 2022

For the substantiation and verification of studies related to the construction of a levee using riverbed soil, real-scale levee construction and experimental studies are essential. One of the most important factors in the experimental study is the reproducibility of the multiple levees with the same initial conditions. Quantitative analysis of the reproducibility should be presented. In this study, a number of physical properties (specific gravity test, sieving test, liquid-plastic limit test, compaction test, on-site Density test) for multiple embankments built with fine-grained bed soil was obtained. The collected data then used to obtain the possibility of reproducing levee through statistical analysis to suggest a process of indicating a numeric initial condition of the real-scale test. As a result of statistical analysis to verify the aforementioned process, it was confirmed that it was possible to quantitatively evaluate the reproducibility of the construction under the same conditions of embankments. This is expected to be a basic data for a full-scale embankment test using riverbed soil including other soil based real-scale tests.

• The Korean Journal of Applied Statistics
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• v.22 no.2
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• pp.317-327
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• 2009

In adaptive designs important components of clinical trials may be changed based on the results of interim analysis. Several international guidelines point out that such interim analysis should be performed by independent experts who do not participate in clinical trials when adaptive designs are used in therapeutic confirmatory clinical trials, and if not, it may cause bias. The international guidelines recommend the establishment of independent data monitoring committee for conducting interim analysis independently.

• Journal of the Korean Data and Information Science Society
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• v.28 no.6
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• pp.1539-1545
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• 2017

In this paper, we analyze and discuss the trend of the probability and statistics problems that have been made in the public secondary school teacher employment exam for mathematics teachers. In order to properly teach the national mathematics curriculum in 2015 in terms of content and function, we investigate the probability and statistics contents that a mathematics teachers should know. We also analyze the contents and trends of the items that have been submitted for 15 years in public secondary school teacher employment exam, and discuss the contents, scope, level and direction of the future contents. In conclusion, considering the significance of the Big Data in the 4th industrial revolution, the problems of statistical thinking of data and probability, exploratory data analysis, sample survey, and statistical inference are needed more.