• Korean Journal of Psychosomatic Medicine
• /
• v.25 no.1
• /
• pp.3-11
• /
• 2017

Objectives : The aim of this study was to draw attention toward so called 'behavioral variant frontotemporal dementia(bvFTD) phenocopy syndrome', which is difficult to discriminate with the primary psychiatric disorders, showing poor response to conventional therapeutic drugs, leading to higher risk to misdiagnoses and legal problems. Furthermore, the author insisted that our interest and study on them must be continued. Methods : English articles published during 2000 thru 2016 had been searched by internet with the combination of words such as 'frontotemporal', 'phenocopy' and 'behavioral', and reviewed. Besides, two clinical vignettes were described. Results : Precise diagnosis is important because patients' behavioral symptoms can influence on their families and community. However, disease-modifying treatment for bvFTD are not developed until now, and recent therapeutic drugs are only good for specific symptoms, while deterioration progresses in spite of proper psychiatric management. The possible bvFTD patients are not progressed into probable bvFTD clinically, showing no decline of cogntive and social function, no decrease of activity function, longer survival time, and normal neuroimaging for several years. Conclusions : Rather than expected, there are much more patients having clinical symptoms, course and diagnostic findings including neuroimaging, which are atypical to classical frontotemporal dementia and primary psychiatric disorders. If our knowledge and discriminating ability is improved, discovery rate of that cases will be increased. However, the identity of these atypical features are not clarified until now, it must be further actively investigated.

• Therapeutic Science for Rehabilitation
• /
• v.8 no.1
• /
• pp.7-25
• /
• 2019

Objective: The purpose of this study was to perform a systematic literature review focusing on international studies to identify various factors affecting the quality of life(QOL) of dementia patients admitted to long-term care facilities. Methods: From January 2000 to July 2018, the articles published in foreign journals were searched through CINAHL and MEDLINE databases. The main search terms were'dementia or Alzheimer's'. 'quality of life', 'long-term care', 'care home', 'nursing home', 'care institution', 'residential care', 'small- scale setting'. The first 1706 articles were searched, but 10 studies were selected using the selection and exclusion criteria. Results: Analysis of ten cross-sectional studies showed that factors such as physical functioning status, ability to perform activities of daily living, and cognition showed a positive correlation with QOL. Depression and anxiety, severity of dementia, and neuropsychiatric symptoms were found to be negatively correlated with QOL. In addition, two longitudinal studies have confirmed that factors affecting QOL are affected by individual functional status and social environmental factors rather than the size and form of care facilities. Conclusion: This study summarized 10 papers and analyzed them through a systematic review of literature. We found that factors such as individual characteristics and social environment determine QOL of patients with dementia. In this study, various intervention methods to improve QOL of patients with dementia should be developed and used in long-term care facilities by identifying the factors affecting QOL of dementia patients and using them.

• Journal of Industrial Convergence
• /
• v.19 no.5
• /
• pp.91-102
• /
• 2021

The purpose of this study was to systematically review about randomized controlled trials the characteristics and effect of cognitive function intervention for patient with dementia. We searched studies published from January 2010 to June 2021 in 5 databases. A total 1,104 studies were found and included 27 studies in final analysis. Methodological quality was assessment with the Cochrane's RoB(risk of bias) tool. Mini-Mental State Examination(MMSE) was the most used as the assessment tool for identifying the cognitive function. Cognitive function intervention were exercise, art, cognitive stimulation, reminiscence, music, multimodal cognitive rehabilitation, virtual reality, horticultural, computerized cognitive training, intentional snoezelen, beauty, cooking, korean traditional familiarity program. Most of the intervention except exercise 2, virtual reality 1, beauty 1 were effective in improving cognitive function. This study provided a clinical evidence for planning and implementing intervention for cognitive function intervention. In the future, various intervention studies suitable for the characteristics of dementia should be conducted by improving the quality of research methods.

• Journal of Digital Convergence
• /
• v.19 no.6
• /
• pp.299-308
• /
• 2021

This study aimed at identifying the significant effects and effectiveness of patients with mild dementia when using personalized reminiscence therapy digital services using AI voice technology. In the process of interpreting the results of stakeholder interviews, the design idea of personal customization using voice AI technology was derived, and prototypes were created and usability tests were conducted in the first and second rounds. The main results are as follows: Since reminiscence therapy itself is highly influenced by personal experience and can receive customized care guides based on treatment status and results through customized treatment programs, the concept of personalization can improve the quality of treatment than existing treatment methods. However, it is expected that the usability of the service will further increase if we study micro-interactions that can prevent errors and increase usability, as issues that may arise due to the forgetting cognitive characteristics of mild dementia patients are observed.

• 한국보건간호학회:학술대회논문집
• /
• 2000.05a
• /
• pp.34-38
• /
• 2000

• 대한예방의학회:학술대회논문집
• /
• 1996.10a
• /
• pp.251-252
• /
• 1996

• The Journal of Bigdata
• /
• v.6 no.1
• /
• pp.37-49
• /
• 2021

The number of dementia patients in Korea is estimated to be over 800,000, and the severity of dementia is becoming a social problem. However, no treatment or drug has yet been developed to cure dementia worldwide. The number of dementia patients is expected to increase further due to the rapid aging of the population. Currently, early detection of dementia and delaying the course of dementia symptoms is the best alternative. This study presented a methodology for early diagnosis of dementia by measuring and analyzing amyloid plaques. This vital protein can most clearly and early diagnose dementia in the retina through AI-based image analysis. We performed binary classification and multi-classification learning based on CNN on retina data. We also developed a deep learning algorithm that can diagnose dementia early based on pre-processed retinal data. Accuracy and recall of the deep learning model were verified, and as a result of the verification, and derived results that satisfy both recall and accuracy. In the future, we plan to continue the study based on clinical data of actual dementia patients, and the results of this study are expected to solve the dementia problem.

• Proceedings of the Korea Information Processing Society Conference
• /
• 2024.05a
• /
• pp.567-568
• /
• 2024

이 연구는 통계청의 치매 사망자수 및 사망률 자료와 공공데이터포털의 서울시 치매안심센터를 분석하여 치매 문제에 초점을 맞추어 치매 환자와 그 가족들에게 지원을 제공하는 치매안심센터의 역할을 조명합니다. 연구 목적은 서울시 각 자치구에 설치된 치매안심센터의 자원과 인프라가 치매 사망률에 미치는 영향을 분석하여, 치매 예방 및 관리 정책의 개선 방향을 제시하는 것입니다. 데이터는 한국통계정보원(KOSIS)과 사망원인통계에서 수집되었으며, 2022 년에 보고된 치매로 인한 사망자 수와 치매관리센터의 자원 정보를 포함합니다. 데이터 전처리 과정에서는 정확성 검증, 정규화, 표준화, 분류 작업이 이루어졌습니다.분석 방법으로는 통계적 접근과 예측 모델링을 통해 치매 치료 센터 자원과 치매 사망률의 관계를 다각적으로 조사했습니다. 본 연구의 결론은 치매 안심 센터의 자원이 치매 사망률에 미치는 영향을 이해하는 데 중요한 정보를 제공하며, 이는 치매 관리와 예방에 있어서 인력의 중요성을 강조합니다.

• Journal of Life Science
• /
• v.15 no.2 s.69
• /
• pp.220-224
• /
• 2005

The purpose of the present study is to investigate the effects of long-term exercise program on exercise capacity and cognitive function (MMSE) in male patients with dementia. 24 male patients were divided into two experimental groups : the exercise group (n=12) and the control group (n=12). The exercise group participated in regular exercise program for 12 months, and their exercise capacity (cardiopulmonary function, muscle strength, muscular endurance, flexibility, balance, agility) and MMSE (Mini-mental state examination) levels were evaluated at baseline (pre), after 6 months (mid) and after 12 months (post). The subjects carried on group-exercise of $VO_{2}max\;30\~60\%$, $30\~60$ minute a day, $2\~3$ times per week. Statistical techniques for data analysis was paired samples t-test. The level of statistical significance was ${\le}.05.$ The results of this study were summarized as follows: In the exercise group, there were significant differences in cardiopulmonary function, muscle strength, muscular endurance and MMSE at the times of pre & mid and pre & post, there were significant differences in balance and agility at the time of pre & post only, whereas there was no significant difference in flexibility following the long-term exercise. In the control group, there were no significant differences in all the times. Based on the results of this particular study, one year exercise program increases on the cognitive function & exercise capacity in male patients with dementia.

• Journal of Korea Entertainment Industry Association
• /
• v.15 no.1
• /
• pp.181-189
• /
• 2021

The purpose of this study is to investigate the relationship between "Mental Status and Dementia Tests" and "predictive diagnosis of severity of dementia". This is a descriptive research, analyze the data collected from Alzheimer's patients and identify which "Mental Status and Dementia Tests" has the most impact to determine the severity of dementia. For this study, Alzheimer's patient's CDR, MMSE-K, SGDS, NPI-Q, BADL and IADL were collected and analyzed. This study will provide a predictive factor to determine the severity of dementia when "Mental Status and Dementia Testss" are being used and also to provide the right treatment. For this study, a total of 617 cases of data from Alzheimer's patients were collected and analyzed with SPSS Statistics. In addition, effective "Mental Status and Dementia Tests" for evaluating the severity of dementia were CDR, ADL, MMSE-K, and SGDS whereas NPI-Q and IADL. Based on the findings of the study, it was recommended to implement more efficient diagnostic method by utilizing a standardized "Mental Status and Dementia Tests".