• Journal of the korean veterinary medical association
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• v.17 no.6
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• pp.52-55
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• 1981

현재까지도 본질병의 원인체인 Eperythozoon에 대한 생활환 감염경로 및 매체등 역학적인 연구가 되어 있지 않은 상태이다. 더욱이 우리나라에서는 본증의 연구 조사가 거의 전국적 규모에서 이루어져 있지 않은 실정인데, 본인등이 건강돈으로 도살되는 성돈에서 $72\%$의 자연 감염율을 관찰할 수 있었으며, 대단위 양돈장에서 높은 자돈의 치사율을 보이는 본증의 유행상을 경험한 점을 감안할때 앞으로 우리나라에서 효과적인 양돈사업의 육성을 위해서 본질병에 대하여 더욱 관심과 연구를 집중해야 될 줄 믿는다. 또한 본 원인균은 일반 전염병 치료제로 많이 애용되는 Sulfa제나 항생제에 대하여 전혀 감수성이 없으며 매독성이 비소제인 Arsphenamine만이 특효가 있다. 점도 임상수의사들이 관심을 기울여야 할 사항이면, 보다 저독성이며 효과적인 치료제 개발도 시급히 요구되는 실정이라 하겠다.

• Korean Journal of Microbiology
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• v.47 no.1
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• pp.1-6
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• 2011

Inefficiency of in vivo gene transfer using currently available vectors reflects a major hurdle in cancer gene therapy. Both viral and non-viral approaches have been described to improve gene transfer efficiency but suffer from a number of limitations. Here we tested an adenovirus carrying the small peptide ligand derived from heregulin${\beta}$ EGF-like domain onto fiber, the adenoviral capsid protein, to deliver transgene to ovarian cancer cells which overexpress ErbB, the cognate receptors for heregulin. The attachement of 53 amino acids to fiber didn't affect on the fiber's trimer structure that is critical for the viral entry to cells. The fiber-modified adenovirus can mediate entry and expression of a ${\beta}$-galactosidase into cancer cells in an increased efficiency compared the unmodified adenovirus. Particularly, the gene transfer efficiency was improved up to 5 times in OVCAR3 cells, an ovarian cancer cell line. Such transduction systems hold promise for delivering genes to ErbB receptor overexpressing cancer cells, and could be used for future cancer gene therapy.

• The Journal of the Korea Contents Association
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• v.8 no.8
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• pp.103-110
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• 2008

In order to verify the effects of cinema therapy on decreasing a sense of uneasiness and improving interpersonal relationship, this study carried out 7 sessions of cinema therapy and consultation with 10 schizophrenia patients. According to the qualitative analysis, the participants were found to be emotionally relaxed through improving their sense of alienation and nervous behaviors as well as revealed the improved interpersonal relationship with communicating lively and expressing actively, Meanwhile, according to the quantitative analysis, 7 of 10 displayed more stable figures than the average of normal people in uneasiness quotient and 6 of 10 showed higher numbers in interpersonal relationship measure. Based on these results, it can be concluded that the treatment applying the cinema therapy has significant effects on decreasing a sense of uneasiness and improving interpersonal relationship.

• The Monthly Diabetes
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• s.210
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• pp.14-16
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• 2007

65세 김모씨는 가족들과 외출을 하려다가 갑자기 발음이 어눌해 지면서 우측에 힘이 빠지기 시작하였다. 가족들은 일단 김씨를 다시 집안으로 데리고 들어와 팔 다리를 주므르고 바늘로 손을 따 보았지만 상태는 점점 악화되어 전혀 말도 못하고 일어설 수 도 없었으며 정신도 흐려지는 등 급속히 악화되었다. 김씨의 아들은 뇌졸중이 아닌가 하는 생각이 들었고 최근에 언론매체를 통해 혈관이 막히는 뇌졸중의 경우에 빨리 병원에 가면 막힌 혈관을 다시 뚫어주는 치료가 가능하다는 이야기를 들은 기억을 떠올렸다. 김씨의 아들은 119에 연락해 아버님을 응급실로 모시고 왔다. 김씨가 병원에 도착한 시간은 증상이 발생한 후 약 1시간 만이였다. 뇌촬영을 비롯한 피검사 등이 시행되었고 의료진은 김씨가 혈관이 막힌 뇌졸중, 즉 뇌경색이라고 하였고, 현재 발병한 지 채 2시간이 지나지 않았으므로 혈관을 뚫어주는 혈전용해술을 시행하겠다고 했다. 혈관이 막힌 원인은 오랫동안 가지고 있던 당뇨, 고혈압, 고지혈증 등이 복합적으로 작용하여 혈관에 동맥경화를 유발하고 있다가 혈전이 생기면서 혈관이 막힌 것이라고 하였다. 그리고 혈관을 막고 있는 혈전을 녹이기 위해 혈전용해술을 시행하는 것이라고 하였다. 뇌출혈등의 부작용이 일부에서 동반될 수 있지만 지금 상태에서 가장 최선의 치료는 혈전용해술이라 것이 의료진의 설명이었다. 다음날 김씨는 완벽하지는 않았지만 말하는 기능과 우측 팔다리 마비가 상당히 호전되었다. 1주일 후 김씨의 상태는 더욱 호전 되었고 열심히 재활치료를 받고 있었다. 김씨와 가족들은 의료진으로부터 꾸준히 재활치료를 하면서 3개월 후 정도면 이전과 거의 비슷한 상태로 회복될 수 있을 것이라는 희망적인 이야기를 들을 수 있었다.

• Journal of Music and Human Behavior
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• v.7 no.1
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• pp.1-15
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• 2010

The purpose of this study is to inquire into the theoretical background of music therapy interventions for the improvement of mathematical concepts among young children with special needs. The researcher provides a basis of theoretical background about musical activities as an effective tool for young children to understand and promote their mathematical concepts, and the necessity of practical application in the field of mathematics education is suggested. Music, as a multi-sensory modality, has an ability to hold and maintain one's attention, and can be used as a memory aid and a powerful and effective motivator and reinforcer for young children. Therefore, musical activities can be used to facilitate mathematical concepts in the field of education for young children. Possible musical activities for promoting mathematical development are suggested, and the necessity for developing various musical activities is discussed.

• Journal of Korean Library and Information Science Society
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• v.48 no.1
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• pp.291-318
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• 2017

In this study, We found out that bibliotherapy program for university student has its strong point and effectiveness. The result of this study are follows: 1) bibliotherapy program is a safe method which covers the advantage of group psychotherapy and make up for the disadvantages. 2) significant changes in imitational behavior, cohesion and acceptance of reality suggest the necessity of bibliotherapy program that focuses on university career. 3) In light of the gloomy reality of young people, the fact that university students discuss love and hope for romance was meaningful phenomenon. It is necessary to study the after reading activities that can enhance the effectiveness of the bibliotherapy program and the specific topics and media that is needed by universities. The study is an approach that is widely available in university and will be the first step to establish the professional direction for bibliotherapy program.

• Trans-
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• v.16
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• pp.1-31
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• 2024

The advent of digital media has facilitated easy access for adolescents to environments conducive to the purchase of narcotics. In particular, there's an increasing trend in the purchase and consumption of narcotics mediated through Social Network Services (SNS) and messenger services. Adolescents, sensitive to such environments, are at risk of experiencing neurological and mental health issues due to narcotic addiction, increasing their exposure to criminal activities, hence necessitating national-level management and support. Consequently, the quest for sustainable treatment methods for adolescents exposed to narcotics emerges as a critical challenge. In the context of high relapse rates in narcotic addiction, the necessity for cost-effective and user-friendly treatment programs is emphasized. This study conducts a literature review aimed at utilizing digital platforms to create an environment where adolescents can voluntarily participate, focusing on the development of therapeutic content through art. Specifically, it reviews societal perceptions and treatment statuses of adolescent drug addiction, analyzes the impact of narcotic addiction on adolescent brain activity and cognitive function degradation, and explores approaches for developing digital therapeutics to promote the rehabilitation of the addicted brain through analysis of precedential case studies. Moreover, the study investigates the benefits that the integration of digital therapeutic approaches and art therapy can provide in the treatment process and proposes the possibility of enhancing therapeutic effects through various treatment programs such as drama therapy, music therapy, and art therapy. The application of art therapy methods is anticipated to offer positive effects in terms of tool expansion, diversification of expression, data acquisition, and motivation. Through such approaches, an enhancement in the effectiveness of treatments for adolescent narcotic addiction is anticipated. Overall, this study undertakes foundational research for the development of digital therapeutics and related applications, offering economically viable and sustainable treatment options in consideration of the societal context of adolescent narcotic addiction.

• Journal of the Korea Convergence Society
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• v.11 no.12
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• pp.261-274
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• 2020

Research on the development and effectiveness of internet-based cognitive-behavioral therapy with a trauma focus (iCBT-T) has been actively conducted in Western societies, but these studies have just begun in Korea. The purpose of this study was to suggest practical considerations to developing and managing the iCBT-T program. After reviewing previous studies on iCBT-T, this author suggested a model of convergence and collaboration between mental health knowledge and information and communication technologies (ICT) to develop the iCBT-T program. This article outlines practical considerations, including focus and target groups of iCBT-T, intervention types of iCBT-T (open access vs. guided), number of sessions, ethical issues, professional support, and degree of user involvement. Methods to complement the limitations of internet as a medium are also proposed in the iCBT-T program. The convergence model of CBT-T and ICT is expected to promote the development of programs that can contribute to improving the mental health of users who experience traumatic events.

• Industry Promotion Research
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• v.5 no.2
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• pp.33-40
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• 2020

When most middle-aged women live in a time when they have to take responsibility for their lives, they feel lonely when they realize that their experience of not expressing their feelings properly has ended up being left alone due to their own existence and loss. As the first step in conscious awareness of unconsciousness of middle-aged women through analytical psychology, we performed "Mandara" and "Nanhwa Mandara," which meet me inside. The intermediate stage can be divided into transition and work phase. The working phase, develops one's own advantages and unique strengths that meet the inner world of promoting and acting values, correctly looks at reality, corrects emotion perception and balance, and is self-contained, seed mandala, associative mandala. They performed the strong points of mandala, the free mandala, and the Western mandala. The results of the study showed that mandala art therapy was found in middle-aged women. First, Mandarin art therapy experience affects the physical, psychological and human relations aspects of middle-aged women. Second, middle-aged women's experience of individualization through mandala art therapy shows psychological reversals and affects positive thinking and self-effectiveness. This study was suitable for qualitative research that approached the essence through practical understanding and direct exploration of research participants, and it is meaningful to suggest that it is necessary to develop an art therapy program through various mediums considering the lack of art therapy research in middle-aged women and problems experienced by the physician.

• Korean Journal of Social Welfare
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• v.65 no.2
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• pp.313-334
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• 2013

A study aims to assess Korean mental health literacy and analyze the characteristics of vulnerable population. This study presented typical vignettes of schizophrenia, depression and alcoholism to 1,197 adults randomly. All respondents were asked for recognition of mental illness, beliefs about causes, professional help and self-help, stigma for receiving psychiatric treatment for the person described. The results showed that the recognition of mental health problem in a vignette was very poor and that personal causes were seen by public as more important than environmental and bio-genetic causes. When the public were asked about various professional therapies and self-help activities, psychotherapy was favored while other professional help were considered to be less helpful than self-help activities. Among professionals, psychiatrist were viewed as most helpful. We used cluster analysis to compare high mental health literacy group with low mental health literacy group(vulnerable population). Vulnerable population were found to be more aged and to live in county area. We proposed government initiated program for enhancing public mental health literacy.