• Title/Summary/Keyword: 측정표준기술

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The Effect of in vitro Hemolysis on Vitamin $B_{12}$ / Folic Acid Results (용혈이 Vitamin $B_{12}$ / Folic acid 검사 결과에 미치는 영향)

  • Kim, Mi-Sook;Cho, Youn-Kyo;Im, Do-Hw;Seo, So-Yeon
    • The Korean Journal of Nuclear Medicine Technology
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    • v.12 no.1
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    • pp.62-65
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    • 2008
  • Purpose: Vitamin $B_{12}$ and folic acid are type of water-soluble vitamin and those work as a secondary vital enzyme, but especially those are involved in the nuclear DNA synthesis. Those are mainly measured in order to diagnose megaloblastic anemia and to assess the storage of folic acid during pregnancy. It is generally known that the hemolyzed serum is useless for folic acid and vitamin $B_{12}$, but it is not easy to abide by this information because our lab (Samkwang Medical Laboratories) is reference laboratory. We tested how much the extent of hemolyzed serum had influence on the results. Materials and Method: We performed the tests of vitamin $B_{12}$, folic acid. For the hemolysis effect study, we used 40 cases. According to the level of A, B and C groups, each group had 10 samples which were mechanically hemolyzed serum. Results: Hemolysis did not affect the vitamin $B_{12}$ results. However in case of folic acid, the value increased according to the degree of hemolysis. And severe hemolyzed cases had the highest value (greater than 20 ng/ml). Conclusions: Preventing the hemolysis, it has to be informed that blood-collecting, separation and storage are performed more carefully. As you see from the above results, hemolyzed serum is not proper for folic acid test, and hemolysis does not affect the results of vitamin $B_{12}$. However, for the more accurate results, it is necessary to avoid hemolysis.

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Design, Implementation and Test of Flight Model of S-Band Transmitter for STSAT-3 (과학기술위성 3호 S-대역 송신기 비행모델 설계, 제작 및 시험)

  • Oh, Seung-Han;Seo, Gyu-Jae;Lee, Jung-Soo;Oh, Chi-Wook;Park, Hong-Young
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.39 no.6
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    • pp.553-558
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    • 2011
  • This paper describes the development and test result of S-band Transmitter flight model(FM) of STSAT-3 by satellite research center(SaTReC), KAIST. The communication sub-system of STSAT-3 is consist of two different frequency band channels, S-band for Telemetry & Command and X-band for mission data. S-band Transmitter(STX) functionally made of modulator, frequency synthesizer, power amp and DC/DC converter. The transmission data is modulated by FSK(Frequency Shift Keying) and the interface between spacecraft sub-module and STX is RS-422 standard method. The FM STX is based on modular design. The RF output power of STX is 1.5W(31.7dBm) and BER of STX is under $1{\times}10^{-5}$ which meets the specification respectively. The FM STX is delivered Spacecraft Assembly, Integration and Test(AIT) level through the completion of functional Test and environmental(vibration, thermal vacuum) Test successfully.

Development of a Spectrum Analysis Software for Multipurpose Gamma-ray Detectors (감마선 검출기를 위한 스펙트럼 분석 소프트웨어 개발)

  • Lee, Jong-Myung;Kim, Young-Kwon;Park, Kil-Soon;Kim, Jung-Min;Lee, Ki-Sung;Joung, Jin-Hun
    • Journal of radiological science and technology
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    • v.33 no.1
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    • pp.51-59
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    • 2010
  • We developed an analysis software that automatically detects incoming isotopes for multi-purpose gamma-ray detectors. The software is divided into three major parts; Network Interface Module (NIM), Spectrum Analysis Module (SAM), and Graphic User Interface Module (GUIM). The main part is SAM that extracts peak information of energy spectrum from the collected data through network and identifies the isotopes by comparing the peaks with pre-calibrated libraries. The proposed peak detection algorithm was utilized to construct libraries of standard isotopes with two peaks and to identify the unknown isotope with the constructed libraries. We tested the software by using GammaPro1410 detector developed by NuCare Medical Systems. The results showed that NIM performed 200K counts per seconds and the most isotopes tested were correctly recognized within 1% error range when only a single unknown isotope was used for detection test. The software is expected to be used for radiation monitoring in various applications such as hospitals, power plants, and research facilities etc.

Usefulness Evaluation of Low-dose CT for Emphysema : Compared with High-resolution CT (폐기종에 대한 저선량 CT의 유용성 평가: 고해상도 CT와 비교)

  • Lee, Won-Jeong
    • Journal of radiological science and technology
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    • v.39 no.3
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    • pp.329-336
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    • 2016
  • The purpose of this study was to evaluate the usefulness of low-dose CT (LDCT) for emphysema compared with high-resolution CT (HRCT). Measurements of radiation dose and noise were repeated 3 times in same exposure condition which was similar with obtaining HRCT and LDCT images. We analysed reading results of 146 subjects. Six images per participants selected for emphysema grading. Emphysema was graded for all 6 zones on the left and right sides of the lungs by the consensus reading of two chest radiologists using a 4-point scale. Between the HRCT and LDCT images, diagnostic differences and agreements for emphysema were analyzed by McNemar's and unweighted kappa tests, and radiation doses and noise by a Mann-Whitney U-test, using the SPSS 19.0 program. Radiation dose from HRCT was significantly higher than that of LDCT, but the noise was significantly lower in HRCT than in LDCT. Diagnostic agreement for emphysema between HRCT and LDCT images was excellent (k-value=0.88). Emphysema grading scores were not significantly different between HRCT and LDCT images for all six lung zones. Emphysema grading scores from LDCT images were significantly correlated with increased scores on HRCT images (r=0.599, p < 0.001). Considering the tradeoff between radiation dose and image noise, LDCT could be used as the gold standard method instead of HRCT for emphysema detection and grading.

Analysis of Voltaic Cell Described in the Science Textbooks of Secondary Schools (중·고등학교 과학 교과서에 제시된 볼타전지에 대한 문제점 분석)

  • Sin, Dong-Hyeok;Lee, Sang-Gwon;Choe, Byeong-Sun
    • Journal of the Korean Chemical Society
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    • v.46 no.4
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    • pp.363-377
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    • 2002
  • The purpose of this study was to improve the problems of the voltaic cell described in the science textbooks of secondary schools. For this purpose, the contents of science textbooks which are related to the voltaic cell were analyzed and the problems which were not explained clearly by theorems were tried to be explained by experiments, and lastly sug-gestions were made toward the improvements regarding the voltaic cell in the science textbooks. The findings are that there are problems on the ways of ensuring whether the voltaic cell operates properly as a chemical battery, on the explanation of why the hydrogen bubbles form at the zinc electrode, on the cell potential, on the unification of the electrode terminology used, and on the mention of the current. Solutions to the problems except the cell potential were suggested. According to the experiment, the theoretical potential was calculated by considering the potentials of redox reactions at the two electrodes of the cell and by taking into account the characteristics of the electrodes such as the work function, ionization energy, stan-dard reduction potential, and electronegativity.The cell potential of the voltaic cell is explained by several factors. In the improved version of the textbook's introduction section to the voltaic cell, it is necessary to describe the voltaic cell his-torically.For the conceptual section, it should be explained in terms of the Daniel cell.

Development of Oxo-biodegradable Transparent Bio Films Using Biomass and Biodegradable Catalyst (바이오매스 및 생분해 촉매제를 이용한 산화생분해 투명 바이오 필름 개발)

  • You, Young-Sun;Kim, Young-Tae;Park, Dae-Sung;Choi, Sung-Wook
    • Clean Technology
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    • v.23 no.2
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    • pp.133-139
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    • 2017
  • Bio-based plastics containing the biomass content higher than 25 wt% have been considered as environment-friendly materials due to their effects on the reduction in the $CO_2$ emission and petroleum consumption as well as biodegradability after use. In this study, poly vinyl chloride, plant-derived plasticizers, by adding a biodegradable catalyst was observed a change in the biodegradability and physical properties. To produce the oxidative decomposition transparent bio film, which is broken down in the initial percent elongation and physical properties such as tensile strength, it was to test the safety of the product as a food packaging material. Poly vinyl chloride, primary plasticizer, secondary plasticizer, anti fogging agent, the combined stabilizer were mixed in a high speed mixer, then extruded using an extrusion molding machine, after cooling, winding, to produce a oxidative decomposition transparent bio film and the control film, with a thickness of $12{\mu}m$ through winder role. Mechanical properties tensile strength, elongation, and the maximum load elongation and biodegradation test. Transparent bio film produced by biodegradation catalyst is compared with the control film. Tensile strength and elongation of films were found to be no significant difference. Further, as a result of the biodegradation test for 45 days based on the ASTM D6954-04 method, biodegrability of film is 61.4%.

The Effects of Anti-Thrombotic Activities and Cardiovascular Improvement of Fermented Garlic Extracts (발효마늘 추출물의 항혈전 및 심혈관개선 효과)

  • Kim, Hyun Kyoung
    • The Journal of the Convergence on Culture Technology
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    • v.6 no.2
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    • pp.567-572
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    • 2020
  • The purpose of this study was to investigate the effects of Anti-Thrombotic Activities and Cardiovascular Improvement of Fermented Garlic Extracts. The incidence of cardiovascular diseases (CVDs) is increasing rapidly in developed countries, with CVDs now representing the leading cause of morbidity and mortality. Natural products and ethnomedicines have been shown to reduce the risk of CVDs. Garlic is a medicinal plant used throughout the world for its anti-inflammatory, antioxidant, and antiplatelet activities. We hypothesized that fermented preparations of these products may possess stronger antiplatelet effects than the non-fermented forms owing to the increased bioavailability of the bioactive compounds produced during fermentation. Therefore, we compared these compounds via in vitro and ex vivo platelet aggregation assays by using standard light transmission aggregometry and ex vivo granule secretions from rat platelets. We found that fermented preparations exerted more potent and significant inhibition of platelet aggregation both in vitro and ex vivo. Likewise, ATP release from dense granules of platelets was also significantly inhibited in fermented preparation-treated rat platelets compared to that in non-fermented preparation-treated ones. We concluded that fermented preparations exerted more potent effects on platelet function both in vitro and ex vivo, possibly as a result of the increased bioavailability of active compounds produced during fermentation. We therefore suggest that fermented products may be potent therapeutics against platelet-related CVDs and can be used as antiplatelet and antithrombotic agents.

Evaluation of the Low Tube Voltage in the Computed Tomography Scan Technique using a Low Concentration Contrast Agent (저농도 조영제를 사용한 CT검사에서 저관전압 기법에 따른 유용성 평가)

  • Jung, Kang-Kyo;Cho, Pyong-Kon
    • Journal of radiological science and technology
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    • v.39 no.1
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    • pp.71-79
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    • 2016
  • The purpose of this study is computed tomography contrast agent at low concentrations and low tube voltage technique to evaluate the usefulness on the phantom image. By varying the degree of mixture by the contrast medium concentration it was inserted in phantom. It was taken by changing the tube voltage and tube current step by step, and to evaluate the dose and the CT value obtained from the phantom image. As a result, low-contrast, low tube voltage(300 mgI/ml, 100 kV) was reduced by an average 21%(CTDIvol; computed tomography dose indexvol) more standard condition(350 mgI/ml, 120 kV). SNR was increased at all depths of the phantom, respectively 1:10 and 1:20(by diluting a contrast agent and normal saline) 12.2(26%) 6.2(17%). CNR was increased at all depths of the phantom, respectively 1:10 and 1:20(by diluting a contrast agent and normal saline) 11.5(32%), 6.3(26%). Research work on the CT scan is necessary in a variety of studies on the low contrast concentration and low tube voltage techniques for dose reduction and reducing of side effects the contrast agent.

A Study on Velocity Distribution Characteristics for Each Location and Effectiveness of Straight Duct Length in a Square-sectional 180° Bended Duct (정사각형 단면을 갖는 180° 곡관에서 위치별 속도분포특성 및 직관거리의 유효성에 관한 연구)

  • Chen, Jing-Jing;Yoon, Jun-Kyu
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.10
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    • pp.618-627
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    • 2016
  • This study numerically analyzes the characteristics of the velocity distribution for each location of a square-sectional $180^{\circ}$ bent duct using a Reynolds Stress Turbulent model. The flow parameters were varied, including the working fluids, inlet velocity, surface roughness, radius of curvature, and hydraulic diameter. The boundary conditions for computational fluid dynamics analysis were inlet temperatures of air and water of 288 K and 293 K, inlet air velocity of 3-15 m/s, inner surface roughness of 0-0.001 mm, radius of curvature of 2.5-4.5 D, and hydraulic diameter of 70-100 mm. The working fluid characteristics were highly affected by changes in the viscous force. The maximum velocity profiles in the bent duct were indicated when the $90^{\circ}$ section was in the region of X/D=0.8 and the $180^{\circ}$ section was in the region of Y/D=0.8. Lower surface roughness and higher radius of curvature resulted in a higher rate of velocity change. Also, an efficient measuring location downstream of the bent duct is suggested since the flow deviations were the most stable when the straight duct length was in the region of L/D=30. The minimum deviations at the same velocity conditions according to the hydraulic diameter were mostly indicated in the range of L/D=15-30 based on the standard deviation characteristics.

The Study of Physiological and Antimicrobial Activities on the Citrus Junos Extracts with its Textures and Skin (유자과즙 추출물의 생리활성 및 항균활성에 관한 연구)

  • Lee, Song Hee;Lee, Moo Sung
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.4
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    • pp.67-74
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    • 2017
  • This study analyzed the antioxidant activities and antibacterial effects of extracts from the fruit of Citrus junos. Theextracts were obtained in both 70% ethanol solution and distilled water at a distillation temperature of $50^{\circ}C$.Three experiments were carried out between November 2016 and March 2017. The averages and the standard deviations of the results were measured. The total polyphenol and tannin contents of the ethanol extracts were $7.8{\pm}0.02mgGAE/g$ and $9.9{\pm}0.01mgTAE/g$, respectively, which were higher than the concentrations in the water extracts. Furthermore, the ethanol extracts scavenged $46.1{\pm}4.76%$ of DPPH radicals and $37.1{\pm}1.23%$ of ABTS radicals. The scavenging capability of the ethanol extracts was also higher than that of the water extracts. However, the scavenging capability of both types of extracts depended on their concentrations.All the extracts showed active antibiosis effects against every bacteria tested except for C. albicans. E. coli at 25 mg/disc showed antibiosis with $18{\pm}1.73mm$ for the water extracts, while S. epidermidis and S. aureus showed antibiosis with $17{\pm}4.36mm$ and $19{\pm}2.86mm$ for the ethanol extracts, respectively. This antibiosis rate is considerably higher. The results suggest that fruit extract from Citrus junos could be useful as a primary material for beauty or skin-related products such as soaps, shampoos, and scalp enhancers.