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Study on the Breast Tissue Uptake according to Body Temperature on Molecular Breast Imaging (Molecular Breast Imaging 검사 시 체온 변화에 따른 유방 섭취율에 관한 고찰)

  • Kim, Ji Hyun;Baek, Song Ee;Oh, Shin Hyun;Ham, Jun Cheol;Kang, Chun Goo;Kim, Jae Sam
    • The Korean Journal of Nuclear Medicine Technology
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    • v.23 no.2
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    • pp.20-24
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    • 2019
  • Purpose Molecular Breast Imaging (MBI) scan is used in nuclear medicine, for which $^{99m}Tc-sestaMIBI$ is administered by intravenous injection. However, the breast uptake rate of $^{99m}Tc-sestaMIBI$ is less than 1% of the total dose administered, relying on blood flow conditions of organs. The purpose of this study is to evaluate the impact of changes to body temperature on the uptake of $^{99m}Tc-sestaMIBI$ in breast tissue. Materials and Methods We investigated 30 breast cancer patients who performed more than one follow-up MBI scan. All scans were acquired by Discovery 750B (Genral Electric Healthcare, USA). $^{99m}Tc-sestaMIBI$ injected with 740 MBq (20 mCi), after 60 minutes, gained bilateral breast CC (CranioCaudal), MLO (Medio Lateral Oblique) View. The follow-up examination was then classified into 15 body temperature control group and 15 body temperature non-control group, and gained breast image in the same way as before. The breast uptake rate was analyzed in the MLO View of the opposite side of the lesion, and blind images were evaluated. Results The breast uptake rate increased by 30.31% in the body temperature control group and it was statistically significant(P<0.05), and 0.96% in the body temperature non-control group, and it was not statistically significant(P=0.955). There was a significant difference in the uptake rate between the body temperature control and the non-control group of P value of 0.01. Evaluation of blind images showed significant results in terms of the quality of the images. Conclusion Increased breast tissue uptake was observed when the subject was kept warm. When the body temperature was raised after injection, dilation of the peripheral blood vessels can be achieved. As a result, the blood flow became smooth and the breast uptake rate increased. In addition, an increase in breast tissue uptake will improve the quality of images.

Monitoring Soil Characteristics and Growth of Pinus densiflora Five Years after Restoration in the Baekdudaegan Ridge (백두대간 마루금 복원사업지에서의 5년 경과 후 토양특성 및 소나무 생장 모니터링)

  • Han, Seung Hyun;Kim, Jung Hwan;Kang, Won Seok;Hwang, Jae Hong;Park, Ki Hyung;Kim, Chan-Beom
    • Korean Journal of Environment and Ecology
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    • v.33 no.4
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    • pp.453-461
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    • 2019
  • This study was conducted to monitor the soil characteristics and growth of Pinus densiflora and to determine the effect of soil characteristics on growth rate five years after an ecological restoration project in Baekdudaegan ridge including Ihwaryeong, Yuksimnyeong, and Beoljae sites. The ecological restoration project was executed with the forest of P. densiflora in 2012-2013. In April 2018, we collected soil samples from each site and measured the height and the diameter at breach height (DBH) of P. densiflora. Although there was no significant change of soil pH compared to the early stage of restoration (one year after the project), it was high in Ihwaryeong, and Beoljae with values of 7.7 and 6.4, respectively. Also, the organic matter decreased by 70-80%, and the available phosphorus (P) was unchanged in three restoration sites. The decreased organic matter can be attributed to restriction of inflow and thus decomposition of litter in the early stage after the restoration. The tree height growth rate ($m\;yr^{-1}$) of P. densiflora in Yuksimnyeong was the highest at 1.02, followed by Beolja at 0.75 and Ihwaryeong at 0.17. The height growth rate showed negative relationships with soil pH and cations, including Na and Ca concentrations and a positive relationship with available phosphate. The low growth rate in the Ihwaryeong site, in particular, might result from the poor nutrient availability due to high soil pH and the decrease in water absorption into the root due to high Na and Ca concentrations. The substantial reduction of organic matter after five years indicates that the need for soil improvement using chemical fertilizer and biochar.

Differences in Urine Cadmium Associations with Renal Damage Markers According to the Adjustment with Specific Gravity or Urinary Creatinine (요비중 또는 크레아티닌 보정에 따른 요중 카드뮴과 신장손상지표와의 관련성 비교)

  • Kim, Yong-Dae;Eom, Sang-Yong;Yim, Dong-Hyuk;Kwon, Soon Kil;Park, Choong-Hee;Kim, Guen-Bae;Yu, Seung-Do;Choi, Byung-Sun;Park, Jung-Duck;Kim, Heon
    • Journal of Life Science
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    • v.29 no.2
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    • pp.265-271
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    • 2019
  • In general, specific gravity (SG) and urinary creatinine (CR) have been used to adjust urinary cadmium (Cd) concentrations. However, the validity of correction methods has been controversial. We compared the two adjustments to evaluate associations between urinary Cd and various renal damage markers and to evaluate the relationship between urinary Cd concentration and renal disease markers, such as estimated glomerular filtration rate (eGFR), in a relatively large general population sample. Among the 1,086 volunteers who were enrolled in this study, 862 healthy volunteers who did not have kidney disease were included in the final analysis. Urinary Cd, malondialdehyde (MDA), and N-acetyl-${\beta}$-D-glucosaminidase (NAG) concentrations were measured, the creatinine-based eGFR was calculated, and the relationships between these markers were subsequently analyzed. This study showed the use of urinary Cd concentration adjusted with SG rather than with urinary creatinine may be appropriate in studies evaluating renal function based on Cd exposure. Urinary Cd concentration adjusted with SG had a positive correlation with urinary MDA levels and a negative correlation with eGFR. This relationship was relatively stronger in women than in men. This study showed that urinary Cd level was associated with decreased eGFR in the general population, and oxidative stress was likely to act as an intermediator in this process. These results suggest that eGFR can be a very good indicator of kidney damage caused by Cd exposure in the general population.

Evaluation of static fracture resistances and patterns of pulpless tooth restored with poly-ether-ketone-ketone (PEKK) post (Poly-ether-ketone-ketone (PEKK) 포스트로 수복한 근관 치료 치아의 정적 파절 저항성 및 파절 형태에 관한 평가)

  • Park, Ha Eun;Lee, Cheol Won;Lee, Won Sup;Yang, Sung Eun;Lee, Su Young
    • The Journal of Korean Academy of Prosthodontics
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    • v.57 no.2
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    • pp.127-133
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    • 2019
  • Purpose: The purpose of present study was to investigate fracture strength and mode of failure of endodontically treated teeth restored with metal cast post-core system, prefabricated fiber post system, and newly introduced polyetherketoneketone (PEKK) post-core system. Materials and methods: A total of 21 mandibular premolar were randomly grouped into 3 groups of 7 each according to the post material. Group A was for metal cast post core; Group B for prefabricated glass fiber post and resin core; and Group C for milled PEKK post cores. All specimens were restored with metal crown. The fracture strength of each specimen was measured by applying a static load of 135-degree to the tooth at 2 mm/min crosshead speed using a universal testing machine. After the fracture strength measurement, the mode of failure was observed. The results were analyzed using Kruscal-Wallis test and post hoc Mann-Whitney U test at confidence interval ${\alpha}=.05$. Results: Fracture resistance of PEKK post core was lower than those of cast metal post and fiber reinforced post with composite resin core. In the aspect of fracture mode most of the root fracture occurred in the metal post core, whereas the post detachment occurred mainly in the fiber reinforced post. In the case of PEKK post core, teeth and post were fractured together. Conclusion: It is necessary to select appropriate materials of post for extensively damaged teeth restoration and clinical application of the PEKK post seems to require more research on improvement of strength.

Effects of Wind Net Shading and Sprinkling on Growing Conditions and Fruit Quality in 'Hongro' and 'Fuji' Apple Fruits (방풍망 차광시설 및 미세살수 처리가 '홍로' 및 '후지' 사과나무의 생육환경 및 과실 품질에 미치는 영향)

  • Kang, Kyeong-Jin;Seo, Jeong-Hak;Yoon, Hong-Ki;Seo, Jeong-Seok;Choi, Taek-Yong;Chun, Jong-Pil
    • Journal of Bio-Environment Control
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    • v.28 no.2
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    • pp.126-133
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    • 2019
  • In recent years, the deterioration of fruit quality caused by poor coloration and sunburn disorder has become serious problems in apple market, which is a result of the increase of surface temperature due to the abnormal temperature increase during summer season. This study was conducted to investigate the effect of wind net shading and fine water spray using sprinkler on fruit coloration, sunburn damage and overall fruit quality of 'Fuji' and 'Hongro' apples. Fifteen sprinklers (7L/hr) were installed at the orchard of the Chungcheongnam-do Agricultural Research and Extension Services, located in Sinam-myeon Chungcheongnam-do Korea, at a height of 3m above the apple tree of $1.5m{\times}3.5m$ north-south direction. Fine water spraying treatment was divided into day time spray (10:00 am to 6:00 pm) and all day spray (10:00 am to 10:00 pm) from early July to 10 days before harvest in 2017 and 2018 season, respectively. Temperature of the surface of apple fruit, characteristic of fruit, and degree of sunburn damage were investigated. In 'Fuji', the fruit surface temperature checked at 2 pm on August 10 was decreased considerably in the day time spray ($35.6^{\circ}C$) and wind net ($39.0^{\circ}C$) when compared with the untreated control ($44.4^{\circ}C$). Similarly, the fruit surface temperature also decreased considerably in the all day spray ($35.1^{\circ}C$) and wind net ($36.9^{\circ}C$) treatments when compared with the untreated control ($46.5^{\circ}C$) in 'Hongro' apples. The incidence of sunburn disorder was significantly decreased with day time spray (5.0%), all day spray (5.8%) and wind net (7.0%) when compared with untreated control (23.4%) in 'Fuji' apples. As a results, the treatment of fine water spray and wind net consequently showed 26% and 34% increase of redness ($a^*$) value in the skin color difference, respectively, in 'Fuji' apples.

Effects of Dietary Supplementation of Enzyme complex on Growth Performance, Carcass Characteristics and Meat storability in Broiler Chickens (사료 내 복합효소제의 첨가가 육계 생산성 및 도체특성 및 저장성에 미치는 영향)

  • Kim, Ki-Hyun;Jeong, Jin-Young;Song, Il-Hwan;Lee, Sung-Dae;Ji, Sang-Yun;Lee, Yoo-Kyong;Nam, Ki-Taeg
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.12
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    • pp.740-748
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    • 2018
  • This study was conducted to investigate the effects of dietary supplementation of enzyme complex (metalloprotease and xylanase) on growth performance, carcass characteristics and meat storability of broiler chickens. The experiment utilized a 2 (basal and low spec diets) ${\times}$ 3 (0, 0.5 or 1 g/kg of enzyme supplementation) factorial arrangement. A total of 360 male Ross broilers were randomly assigned into the following six groups: BD-T0 (basal diet + enzyme complex 0 g/kg), BD-T1 (basal diet + enzyme complex 0.5 g/kg), BD-T2 (basal diet + enzyme complex 1 g/kg), LD-T0 (low spec diet + enzyme complex 0 g/kg), LD-T1 (low spec diet + enzyme complex 0.5 g/kg), LD-T2 (low spec diet + enzyme complex 1 g/kg). Feed and water were provided ad libitum for 42 days, during which time feed intake and body weight were measured at one-week intervals. After the feeding trial, chickens were slaughtered by exsanguination and samples were collected. Feed intake was lower in the enzyme supplemented groups than the non-supplemented groups (p<0.05), as were body weight and gain (p<0.05). Thus, the feed conversion ratio improved in the enzyme supplemented groups relative to the non-supplemented groups (p<0.05). The carcass rate and production index were also significantly improved by supplementation with enzyme complex (p<0.05). Finally, the thiobarbituric acid reactive substances (TBARS) values were lower in the enzyme supplementation groups after 6 storage days (p<0.05). In conclusion, dietary supplementation with enzyme complex including metalloprotease and xylanase improved growth performance, carcass characteristics, and storability of broiler chicken meat.

Functional screening of Asparagus officinalis L. stem and root extracts (아스파라거스 줄기 및 뿌리 추출물의 기능성 검증)

  • Han, Joon-Hee;Hong, Min;Lee, Jaehak;Choi, Da-Hye;Lee, Sun-Yeop;Kwon, Tae-Hyung;Lee, Jae-Hee;Lee, Yong-Jin;Yu, Keun-Hyung
    • Korean Journal of Food Science and Technology
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    • v.53 no.1
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    • pp.46-54
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    • 2021
  • The biological activities of non-edible extracts of asparagus stems and roots were investigated using hot water and ethanol. The highest contents of rutin and total polyphenol were 31.74 mg/g and 20.14 mg GAE/g, respectively, in the stem hot water extract. ABTS and DPPH radical scavenging activities were 541.1±21.0 and 649.5±6.6 ㎍/mL, respectively, in stem hot water extract. All extracts were non-cytotoxic in HepG2 cells, but 200 ㎍/mL stem extracts tended to decrease the viability of RAW 264.7 cells. The highest xanthine oxidase inhibitory activity was 43.68% in the root hot water extract at 200 ㎍/mL. The expression level of MMP-9 was significantly decreased in the asparagus extracts. The highest GGT, AST, and LDH activities showed a concentration-dependent decrease in the stem ethanol extract. In conclusion, the presence of bioactive substances in the non-edible extracts of asparagus was confirmed for the development of extracts with antioxidant, hepatoprotective and anti-gout activities.

Human Thermal Environment Analysis with Local Climate Zones and Surface Types in the Summer Nighttime - Homesil Residential Development District, Suwon-si, Gyeonggi-do (Local Climate Zone과 토지피복에 따른 여름철 야간의 인간 열환경 분석 - 경기도 수원시 호매실 택지개발지구)

  • Kong, Hak-Yang;Choi, Nakhoon;Park, Sookuk
    • Ecology and Resilient Infrastructure
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    • v.7 no.4
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    • pp.227-237
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    • 2020
  • Microclimatic data were measured, and the human thermal sensation was analyzed at 10 local climate zones based on the major land cover classification to investigate the thermal environment of urban areas during summer nighttime. From the results, the green infrastructure areas (GNIAs) showed an average air temperature of 1.6℃ and up to 2.4℃ lower air temperature than the gray infrastructure areas (GYIAs), and the GNIAs showed an average relative humidity of 9.0% and up to 15.0% higher relative humidity. The wind speed of the GNIAs and GYIAs had minimal difference and showed no significance at all locations, except for the forest location, which had the lowest wind speed owing to the influence of trees. The local winds and the surface roughness, which was determined based on the heights of buildings and trees, appeared to be the main factors that influenced wind speed. At the mean radiant temperature, the forest location showed the maximum value, owing to the influence of trees. Except at the forest location, the GNIAs showed an average decrease of 5.5℃ compared to GYIAs. The main factor that influenced the mean radiant temperature was the sky view factor. In the analysis of the human thermal sensation, the GNIAs showed a "neutral" thermal perception level that was neither hot nor cold, and the GYIAs showed a "slightly warm" level, which was a level higher than those of the GNIAs. The GNIAs showed a 3.2℃ decrease compared to the GYIAs, except at the highest forest location, which indicated a half-level improvement in the human thermal environment.

Design and Implementation of a Similarity based Plant Disease Image Retrieval using Combined Descriptors and Inverse Proportion of Image Volumes (Descriptor 조합 및 동일 병명 이미지 수량 역비율 가중치를 적용한 유사도 기반 작물 질병 검색 기술 설계 및 구현)

  • Lim, Hye Jin;Jeong, Da Woon;Yoo, Seong Joon;Gu, Yeong Hyeon;Park, Jong Han
    • The Journal of Korean Institute of Next Generation Computing
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    • v.14 no.6
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    • pp.30-43
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    • 2018
  • Many studies have been carried out to retrieve images using colors, shapes, and textures which are characteristic of images. In addition, there is also progress in research related to the disease images of the crop. In this paper, to be a help to identify the disease occurred in crops grown in the agricultural field, we propose a similarity-based crop disease search system using the diseases image of horticulture crops. The proposed system improves the similarity retrieval performance compared to existing ones through the combination descriptor without using a single descriptor and applied the weight based calculation method to provide users with highly readable similarity search results. In this paper, a total of 13 Descriptors were used in combination. We used to retrieval of disease of six crops using a combination Descriptor, and a combination Descriptor with the highest average accuracy for each crop was selected as a combination Descriptor for the crop. The retrieved result were expressed as a percentage using the calculation method based on the ratio of disease names, and calculation method based on the weight. The calculation method based on the ratio of disease name has a problem in that number of images used in the query image and similarity search was output in a first order. To solve this problem, we used a calculation method based on weight. We applied the test image of each disease name to each of the two calculation methods to measure the classification performance of the retrieval results. We compared averages of retrieval performance for two calculation method for each crop. In cases of red pepper and apple, the performance of the calculation method based on the ratio of disease names was about 11.89% on average higher than that of the calculation method based on weight, respectively. In cases of chrysanthemum, strawberry, pear, and grape, the performance of the calculation method based on the weight was about 20.34% on average higher than that of the calculation method based on the ratio of disease names, respectively. In addition, the system proposed in this paper, UI/UX was configured conveniently via the feedback of actual users. Each system screen has a title and a description of the screen at the top, and was configured to display a user to conveniently view the information on the disease. The information of the disease searched based on the calculation method proposed above displays images and disease names of similar diseases. The system's environment is implemented for use with a web browser based on a pc environment and a web browser based on a mobile device environment.

Trends in QA/QC of Phytoplankton Data for Marine Ecosystem Monitoring (해양생태계 모니터링을 위한 식물플랑크톤 자료의 정도 관리 동향)

  • YIH, WONHO;PARK, JONG WOO;SEONG, KYEONG AH;PARK, JONG-GYU;YOO, YEONG DU;KIM, HYUNG SEOP
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.26 no.3
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    • pp.220-237
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    • 2021
  • Since the functional importance of marine phytoplankton was firstly advocated from early 1880s massive data on the species composition and abundance were produced by classical microscopic observation and the advanced auto-imaging technologies. Recently, pigment composition resulted from direct chemical analysis of phytoplankton samples or indirect remote sensing could be used for the group-specific quantification, which leads us to more diversified data production methods and for more improved spatiotemporal accessibilities to the target data-gathering points. In quite a few cases of many long-term marine ecosystem monitoring programs the phytoplankton species composition and abundance was included as a basic monitoring item. The phytoplankton data could be utilized as a crucial evidence for the long-term change in phytoplankton community structure and ecological functioning at the monitoring stations. Usability of the phytoplankton data sometimes is restricted by the differences in data producers throughout the whole monitoring period. Methods for sample treatments, analyses, and species identification of the phytoplankton species could be inconsistent among the different data producers and the monitoring years. In-depth study to determine the precise quantitative values of the phytoplankton species composition and abundance might be begun by Victor Hensen in late 1880s. International discussion on the quality assurance of the marine phytoplankton data began in 1969 by the SCOR Working Group 33 of ICSU. Final report of the Working group in 1974 (UNESCO Technical Papers in Marine Science 18) was later revised and published as the UNESCO Monographs on oceanographic methodology 6. The BEQUALM project, the former body of IPI (International Phytoplankton Intercomparison) for marine phytoplankton data QA/QC under ISO standard, was initiated in late 1990. The IPI is promoting international collaboration for all the participating countries to apply the QA/QC standard established from the 20 years long experience and practices. In Korea, however, such a QA/QC standard for marine phytoplankton species composition and abundance data is not well established by law, whereas that for marine chemical data from measurements and analysis has been already set up and managed. The first priority might be to establish a QA/QC standard system for species composition and abundance data of marine phytoplankton, then to be extended to other functional groups at the higher consumer level of marine food webs.