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http://dx.doi.org/10.9721/KJFST.2021.53.1.46

Functional screening of Asparagus officinalis L. stem and root extracts  

Han, Joon-Hee (Department of Research and Development, Chuncheon Bioindustry Foundation)
Hong, Min (Department of Research and Development, Chuncheon Bioindustry Foundation)
Lee, Jaehak (Department of Applied Animal Science, College of Animal Life Sciences, Kangwon National University)
Choi, Da-Hye (Department of Research and Development, Chuncheon Bioindustry Foundation)
Lee, Sun-Yeop (Department of Research and Development, Chuncheon Bioindustry Foundation)
Kwon, Tae-Hyung (Department of Research and Development, Chuncheon Bioindustry Foundation)
Lee, Jae-Hee (Agro-food Research Institute, Gangwondo Agricultural Research and Extension Services (ARES))
Lee, Yong-Jin (Department of Research and Development, Chuncheon Bioindustry Foundation)
Yu, Keun-Hyung (Department of Research and Development, Chuncheon Bioindustry Foundation)
Publication Information
Korean Journal of Food Science and Technology / v.53, no.1, 2021 , pp. 46-54 More about this Journal
Abstract
The biological activities of non-edible extracts of asparagus stems and roots were investigated using hot water and ethanol. The highest contents of rutin and total polyphenol were 31.74 mg/g and 20.14 mg GAE/g, respectively, in the stem hot water extract. ABTS and DPPH radical scavenging activities were 541.1±21.0 and 649.5±6.6 ㎍/mL, respectively, in stem hot water extract. All extracts were non-cytotoxic in HepG2 cells, but 200 ㎍/mL stem extracts tended to decrease the viability of RAW 264.7 cells. The highest xanthine oxidase inhibitory activity was 43.68% in the root hot water extract at 200 ㎍/mL. The expression level of MMP-9 was significantly decreased in the asparagus extracts. The highest GGT, AST, and LDH activities showed a concentration-dependent decrease in the stem ethanol extract. In conclusion, the presence of bioactive substances in the non-edible extracts of asparagus was confirmed for the development of extracts with antioxidant, hepatoprotective and anti-gout activities.
Keywords
anti-gout; antioxidant; asparagus; hepatoprotective; rutin;
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