• Radiation Oncology Journal
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• v.27 no.3
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• pp.120-125
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• 2009

Purpose: We wanted to present the preliminary results of intensity-modulated radiotherapy (IMRT) for the treatment of tonsillar cancer. Materials and Methods: We retrospectively analyzed 12 patients who underwent IMRT for tonsillar cancer at Asan Medical Center between November 2002 and February 2007. Seven patients (58%) received definitive treatment, and five (42%) were treated in the postoperative setting. Among the definitively treated patients, 6 patients received cisplatin-based chemotherapy regimens. Simultaneous modulated accelerated radiation therapy (SMART) was used in nine patients. The prescribed dose was 72 Gy at 2.4 Gy/fraction for the definitively treated cases and 61.6 Gy at 2.2 Gy/fraction for the postoperative cases. The median follow-up period was 34 months. Results: All twelve patients completed treatment without interruption, and eleven showed a complete response. One patient had persistent loco-regional disease after treatment. The three-year estimates of loco-regional control, disease-free survival and overall survival were 91.7%, 91.7%, and 100%. The worst acute mucositis was Grade 1 in four patients, Grade 2 in five patients, Grade 3 in two patients and Grade 4 in one patient. Grade 3 xerostomia was observed in six patients. Conclusion: Intensity-modulated radiotherapy was shown to be a safe and effective treatment modality for tonsillar cancer. Further studies with a larger number of patients and a longer follow-up period are needed to evaluate the ultimate tumor control and late toxicity of IMRT for treating tonsillar cancer.

• Applied Biological Chemistry
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• v.38 no.2
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• pp.141-146
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• 1995

Changes of physicochemical properties of citron juice prepared by two different extraction methods, rotary-crushing and belt-pressing method, were investigated during the storage at $5^{\circ}C$ and $-20^{\circ}C$. Temperature drop of citron juice extracted by belt-pressing method was faster than that of citron juice prepared by rotary-crushing method and its freezing point was $0.8{\sim}0.9^{\circ}C$. During the storage, pH of stored citron juice with rotary-crushing method was increased up to 3.5 after 6 months storage while that of citron juice extracted by belt-pressing method was not changed significantly during the same storage time. Acidity of rotary-crushed citron juice was reduced a little more than that of belt-pressed citron juice during the storage. However, changes of soluble solid content were influenced largely by the storage temperature than by the extraction method. Contents of formol nitrogen and vitamin C were reduced remarkably in all of stored citron juice and $92{\sim}82%$ of farmol nitrogen and $72{\sim}43%$ of vitamin C were remained after 6 months of storage. Among the changes of color value, L values were reduced in the whole stored citron juice and a and b value had a different change pattern respectively according to the extraction and storage temperature. Changes in the content of both amino acid and fatty acid compositions was also observed after same storage period. Especially, in the case of change of fatty acid composition, content of linoleic acid and linolenic acid were reduced after 6 months storage, while those of palmitic acid, stearic acid and oleic acid were increased.

• Korean Journal of Environmental Agriculture
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• v.27 no.4
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• pp.303-313
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• 2008

This research is aimed to investigate the cultivation method of oyster mushroom[Pleurotus ostreatus (Jacq. ex Fr.) Kummer] at the non-sterilized medium with $Ca(OH)_2$ treatment. Therefore, experiments were carried out to develop non-sterilization method of medium by addition of $Ca(OH)_2$ for omission of heat sterilization progress of medium. General components, minerals and amino acid in Jiri wild type No. 1 (Pleurotus ostreatus) and production cost were analyzed. For the purpose of omission of heat sterilization progress, treatment ratio of $Ca(OH)_2$ (purity 95%) was 5%(w/w) of dry medium. Initial pH of this medium was 11 and then the pH was changed by 9 after the uniform mixing of the medium for half an hour. The various germs occurred 50% and 100% at pH 8 and pH 7 of the non-sterilized medium, respectively. Production of oyster mushroom increased by $2,030\;ton\;ha^{-1}$ when the main raw material used corn pith instead of waste cotton. The time required of mycelium culture was 30 days when hypha was cultured at the non-sterilized medium, and pinhead occurred when 2 or 3 days was passed after the time required of mycelium culture. Occurrence of pinhead was most rapid at the condition of $22{\sim}26^{\circ}C$, 65% humidity and pH $6.5{\sim}7.0$ and required of $22{\sim}28$ days at $70{\sim}80\;mm$ thickness of non-sterilized medium. Ca content in 1st harvest oyster mushroom was higher than that in 2nd harvest one, and its difference was $30.3\;mg\;kg^{-1}$. Amino acid content by stipe thickness of oyster mushroom was ranged from 411.2 to $343.9\;mg\;kg^{-1}$ both in a pileus and a stipe of 1st harvest mushroom, and from 402.4 to $498.2\;mg\;kg^{-1}$ and from 442.6 to $470.4\;mg\;kg^{-1}$ in those of 2nd harvest one, respectively. The results of the present study suggest that the non-sterilization medium by addition of $Ca(OH)_2$ is usable with the cultivation of oyster mushroom.

• Journal of Animal Environmental Science
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• v.17 no.2
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• pp.115-122
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• 2011

This study was conducted to investigate the changes in growth performance, blood hormone levels and immunity of weaning pigs by the installation of warm curtain for keeping warmth in pigpen. A total of sixty-four piglets was weaned at 21 d of age with an average body weight of 5.8 kg. Each thirty-two piglets were allocated into the pens with (TRT) or without warm curtain (CONT). Daily gain and feed intake were increased by 17% and 9% in TRT from 2nd week to 4th week compared with CONT, respectively. The occurrence of diarrhea was decreased by 62% in TRT from initial to 2nd week compared with CONT. There were no significant differences in blood hormone levels and immunity of weaning pigs between treatments. In conclusion, the installation of warm curtain, which supported high temperature in pigpen, was considered to be effective in improving growth performance and reducing diarrhea occurrence of weaning pigs.

• Food Science and Preservation
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• v.20 no.5
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• pp.744-750
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• 2013

The indigenous Saccharomyces cerevisiae strains S13 and D8 were isolated at the microbial succession stage during spontaneous fermentation of Campbell Early wine as a resistant to potassium metabisulfite and a high sugar concentration. In this study, the fermentation characteristics of Campbell Early wine were investigated and compared with those of S. cerevisiae W-3, an industrial wine yeast. Alcohol production by the two strains was delayed at the initial fermentation stage, but increased fast when the fermentation continued. After the fermentation, the S13 and D8 wines contained 12.6% and 13.2% (v/v) alcohol, respectively, which were significantly higher than the alcohol content of the W-3 wine (12%, v/v). No marked differences were observed in the residual soluble solid content and the pH. However, the S13 and D8 wines showed high levels of total acid content, including malic and lactic acids. Especially, the lactic acid content was 8.9-fold in the S13 wine and six-fold in the D8 wine, compared with that of the W-3 wine. The two strains produced a higher level of acetaldehyde and a lower amount of methanol in the wine than the W-3 strain. The iso-Butanol content was lower in the two indigenous yeast wines with similar levels of n-propanol and iso-amyl alcohol contents than that in the W-3 wine. In the sensory evaluation, the S13 and D8 wines had higher scores for their color, flavor, taste and overall preferences than the W-3 wine. Especially, the S13 and D8 wines had much higher scores than the W-3 wine for flavor and color, respectively.

• Journal of the East Asian Society of Dietary Life
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• v.22 no.1
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• pp.41-51
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• 2012

We produced Hwanggiju (added 0.5~2.0% of ground Astragali Radix compared to starch contents) and investigated the physicochemical characteristics, DPPH free radical scavenging activities, polyphenol contents, and sensory evaluation. For all treatments, the initial pH was 3.9~4.1 and gradually decreased for 6 days from the 1st mashing day, and then rapidly increased to 4.67. As the fermentation proceeded, total acid contents increased in most of the treatments, reduced temporarily after the 2nd mashing time because of the addition of starch material and water, and then slightly rose again. There were little changes in pH and total acid contents followed by adding ground Astragali Radix (AR) to the fermentation periods. Amino acidities of all treatments showed patterns of which consistently rose as the fermentation proceeded and slightly reduced followed by increasing the addition rate of ground AR to the mashes. Soluble solid and alcohol contents also increased continuously and there were few differences among the treatments followed by adding to the ground AR rate. In color, there was no differences in L value, but a and b value showed significant differences by adding ground AR rate. In DPPH free radical scavenging activities, the control (no AR added) showed 53.6% and when grinded AR added, there were improving effects of the activities (0.52~6.9%). In polyphenol contents, the control was 1.05 mg/mL and the ground AR added treatments increased slightly. In the sensory evaluation, the control received a relatively high score ($5.0{\pm}1.0$), and the treatments which added 0.5% ground AR during the 2nd mashing time were also well received ($4.5{\pm}1.3$).

• The Journal of Korean Academy of Prosthodontics
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• v.49 no.2
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• pp.168-176
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• 2011

Purpose: This study aims at investigating the influence of various insertion torques on thermal changes of bone. A proper insertion torque is derived based on the thermal analysis with two different implant designs. Materials and methods: For implant materials, bovine scapula bone of 15 - 20 mm thickness was cut into 35 mm by 40 - 50 mm pieces. Of these, the pieces having 2 - 3 mm thickness cortical bone were used as samples. Then, the half of the sample was immersed in a bath of $36.5^{\circ}C$ and the other half was exposed to ambient temperature of $25^{\circ}C$, so that the inner and surface temperatures reached $36.5^{\circ}C$ and $28^{\circ}C$, respectively. Two types of implants ($4.5{\times}10\;mm$ Br${\aa}$nemark type, $4.8{\times}10\;mm$ Microthread type) were inserted into bovine scapula bone and the temperature was measured by a thermocouple at 0.2 mm from the measuring point. Finite element method (FEM) was used to analyze the thermal changes at contacting surface assuming that the sample is a cube of $4\;cm{\times}4\;cm{\times}2\;cm$ and a layer up to 2 mm from the top is cortical bone and below is a cancellous bone. Boundary conditions were set on the basis of the shape of cavity after implants. SolidWorks was used as a CAD program with the help of Abaqus 6.9-1. Results: In the in-vitro experiment, the Microhead type implant gives a higher maximum temperature than that of the Br${\aa}$nemark type, which is attributed to high frictional heat that is associated with the implant shape. In both types, an Eriksson threshold was observed at torques of 50 Ncm (Br${\aa}$nemark) and 35 Ncm (Microthread type), respectively. Based on these findings, the Microthread type implant is more affected by insertion torques. Conclusion: This study demonstrate that a proper choice of insertion torque is important when using a specific type of implant. In particular, for the Microthread type implant, possible bone damage may be expected as a result of frictional heat, which compensates for initial high success rate of fixation. Therefore, the insertion torque should be adjusted for each implant design. Furthermore, the operation skills should be carefully chosen for each implant type and insertion torque.

• Journal of Animal Science and Technology
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• v.50 no.3
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• pp.343-354
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• 2008

The objective of this study was to investigate the effect of restricted feeding to pullet on growth and endocrine profile in layers(Isa brown). One thousand eighty brown-layer chicks were divided into three treatments; conventional feeding(ad libitum) and two restricted feedings(80% of conventional diet) for 70 weeks. One of restricted feeding started from seven to seventeen weeks of age, and the other started from twelve to seventeen weeks of age. Diets were formulated by NRC(1994) recommendation. Body weight and feed intake were measured every two weeks, and body composition and organ weight analyzed every week in rearing period and every eight weeks in laying period. Blood was collected at weighing body weight and was analyzed for the concentration of insulin-like growth factor-Ⅰand estradiol. Body weight and feed intake decreased as restriction of feeding begins comparing to ad libitum group(P<0.05), but reached to similar body weight and feed intake at 20 wk of age regardless of restriction. There were no significant differences in development of digestive tract and attached organs among the treatment groups. During rearing period, however, they were slightly higher in restricted group which was low in body weight. In terms of body composition, fat contents of restricted group were significantly lower(P<0.05) than that of ad libitum group around 1,000 grams of body weight. High concentration of IGF-Ⅰwas observed.

• The Korean Journal of Pesticide Science
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• v.9 no.4
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• pp.316-329
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• 2005

Mobility of pesticides can be occurred by run-off and leachate or soil erosion. It is one of the most important factors for environmental contamination, particularly in steep sloped-land as Gangwon alpine region. In this study, the mobility of seven pesticides in different slopes and soil textures was investigated by simulated rainfall under controlled conditions. Simulated rainfall subjected to 60 mm $hr^{-1}$ was treated using rainfall simulator after 12 hr of pesticide treatment. Amounts of the pesticides were measured in run-off and leachate samples. The soil samples collected after rainfall from upper and lower parts and three different depths of sloped-plot were also analyzed. At result, all pesticides from the un-off samples collected from Taebaek(silty clay loam) and Heongseong(sandy loam) soils were detected maximum 96% within 60 minutes after first collection except carbendazim and cypermethrin which have the lowest water solubilities. From the leachate samples, a similar pattern was shown as run-off samples but amount of pesticides was lower than those of run-off samples. In soil samples, the order of the amount of pesticide residues was $0{\sim}5$ > $5{\sim}10$ > $10{\sim}15$ cm of soil depth and no pattern was shown in upper and lower, and different slopes. Comparing to mobility of pesticides in water and soil samples, pesticides in soil samples were higher than those of water samples in Taebaek soil. However, the results using Heongseong soils were in contrast to those of Taebaek soil. These results revealed that mobility of pesticides can be dependant mainly on soil textures and physicochemical properties of pesticides. Therefore, it can be suggested that selection of pesticides should be considered for soil texture and properties of pesticide in the alpine and sloped-land.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.9
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• pp.4602-4609
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• 2013

In summer and winter, the difference between the temperature during the day and that during the night is high, which leads to various problems during concrete placement, such as cracks and defects in the concrete as well as low durability and strength. Although nuclear power plant concrete is widely used for placement in all seasons, particular attention must be paid to its quality during the summer. Therefore, we evaluated the effects of a cooling method for mixing water, which is a commonly used hot weather precooling method, and the use of a retarder, on the characteristics of Nuclear Power Plant concrete. In the cooling method for mixing water, cold water at 5 was used, with 50% of the water content consisting of ice flakes. The effects of using a retarder were evaluated by reviewing the characteristics of the cement at the unset stage and after hardening. To evaluate the characteristics of the unset cement, we measured the slump, air volumes, setting times, and pressure strengths after hardening. Furthermore, we measured the heat of hydration at different temperatures; the loss of heat was minimized using insulation. Both the slump time and the complete ageing time of the air volume were found to be 120 min at $20^{\circ}C$ and 40 min at $40^{\circ}C$. In the case when the cooling method for mixing water was used and in the case when a retarder was used, the initial and final sets by penetration resistance were delayed, and the delay decreased with increasing air temperature. For the heat of hydration, the cooling method for mixing water not only lowered the maximum temperature but also delayed its attainment. However, the use of a retarder had no effect on the maximum temperature. Moreover, in the early ages (e.g., 3 and 7 days), the pressure strength of the concrete was lower than that of plain cement. However, the strength of 28-day concrete met the standard construction specifications.