• Journal of Digital Convergence
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• v.16 no.12
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• pp.533-540
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• 2018

The purpose of this study was to use the data from the Health Insurance Review and Assessment Service to analyze the disagreement in disease coding given by different medical institutions on the same disease of the same patient and provide basic data that could help improve the quality of national public health statistics. 9,976,826 patients' data records from the Health Insurance Review and Assessment Service-National Patient Sample (HIRA-NPS) of 2014 were analyzed. The disagreement in disease coding differed by movement paths for medical institutions; the disagreement rate tended to increase when moving from a medical institution other than public health centers to a public health center and decrease remarkably when moving from a specialized general hospital to another. Therefore, this analysis of disagreement in disease coding among medical institutions suggests the need to supplement the system so that domestic medical institutions can realize consistent disease coding.

• Proceedings of the Korean Information Science Society Conference
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• 2003.10b
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• pp.688-690
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• 2003

본 논문에서는 다해상도 2차원 실루엣 영상들을 이용하여 3차원 모델간의 형상 유사성을 비교하기 위한 방법을 제안한다. 제안 시스템은 포즈 정규화 모듈, 유사성 계산 모듈, 3차원 시각화 모듈로 구성된다. 형상 비교를 위해서 먼저, 3차원 인체 장기 모델을 입력으로 받아서 정규화를 수행하고, 다해상도 깊이맵을 획득한다. 이어서 유사성 비교를 위해 실루엣 영상을 추출한 후, 유사도 측정을 위해 시그니쳐를 측도로 사용한다. 최종적으로 계산된 결과들은 3차원 글리프 및 컬러 코딩을 이용하여 시각화된다. 본 논문에서 제시한 3차원 형상 비교 시스템은 전처리 단계에서의 정규화 수행을 통하여 스케일 및 회전 변환에 불변하는 특성을 보인다. 그리고 다양한 레벨의 깊이맵을 형상 비교에 사용하여 다해상도 기반의 유사성 평가를 지원하며, 평가 계산 속도와 정확성간의 유연성을 제공한다. 또한 3차원 히스토그램. 3차윈 글리프. 컬러 코딩 시각화 기법들과 2차원 실루엣 피킹 인터페이스를 통하여 인체 장기 모델간의 정량적 형상 차이를 사용자가 직관적으로 평가할 수 있도록 한다. 본 시스템은 차후 데이터베이스를 이용한 원격 진료 시스템에서의 질병 진단, 추적 관찰. 치료계획 등에 활용될 수 있을 것이다.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.12
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• pp.381-393
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• 2016

This was a qualitative study to explore and better understand the adaptation experience and processes of peoples with fibromyalgia syndrome (FMS), as well as to develop a substantive theory using the grounded theory method. There were 13 patients (12 females and 1 male) who received FMS treatment from Rheumatic Medicine outpatient department of one general hospital. The data were collected through an in-depth interview between January and May of 2014. Transcribed interview contents were analyzed by the grounded theory method of Corbin and Strauss (2008). As a result, a total of 98 concepts, 26 sub-categories, and 10 categories were identified through the open coding process. The process of adaptation experience showed 4 steps: perception of uncertainty and limited condition, evaluation of self-control possibility and determinations of expectations of life, searching and trying of strategies, as well as self-regulation. The 4 types of adaptation experience were expansionary, complacently, effusively and withering. The 'protective self-regulation' theory was derived from the core category of 'learning to self-regulation method'. Patients with FMS has repeatedly attempted these strategies of protective self-regulation in order to gain stability from uncertainty and limited condition of the disease. Based on these results, it is necessary to develop an educational program for patients and families which has appropriate nursing intervention strategies in accordance with the types of adaptation.

• Journal of Digital Convergence
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• v.14 no.3
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• pp.235-241
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• 2016

Among recent issues emerging in the areas related to the society, health has received the most attention. In this paper, for a patient unable to do self-care because of worsened diseases, a biological information transfer method is proposed by which the disease information can be securely managed, by attaching an implantable device into the body. Our method object of the invention is to prevent a third party from illegally intercepting and interfering with the biological information attached to the insertion device in the body. In the proposed technique to improve the safety of the patient between the hospital and physician by assigning each code to the biometric information of the patient in order to prevent a third party tapping and interfering. In addition, our method is assigned a code necessary for encoding in advance to confirm the biological information between the patient and the hospital (doctor) in a manner dividing the bio-information code. In particular, the proposed technique makes a third party unable to illegally tap or interfere in, by previously generating a code used for encoding so that it can be stored in the database of the hospital, which not only decreased hospital care time to 6.9%, but also increased work efficiency rate up to 12.7%.

• Journal of Genetic Medicine
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• v.7 no.2
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• pp.119-124
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• 2010

More than 7,000 rare Mendelian diseases have been reported, but less than half of all rare monogenic disorders has been discovered. In addition, the majority of mutations that are known to cause Mendelian disorders are located in protein-coding regions. Therefore, exome sequencing is an efficient strategy to selectively sequence the coding regions of the human genome to identify novel genes associated with rare genetic disorders. The "exome" represents all of the exons in the human genome, constituting about 1.5% of the human genome. Exome sequencing is carried out by targeted capture and intense parallel sequencing. After the first report of successful exome sequencing for the identification of causal genes and mutations in Freeman Sheldon syndrome, exome sequencing has become a standard approach to identify genes in rare Mendelian disorders. Exome sequencing is also used to search the causal genes and variants in complex diseases. The successful use of exome sequencing in Mendelian disorders and complex diseases will facilitate the development of personalized genomic medicine.

• Journal of Agricultural Extension & Community Development
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• v.23 no.3
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• pp.221-232
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• 2016

This study aims to improve the Korean Farmers' Occupational Disease and Injury Survey (KFODIS), using the questionnaire improvement model, and systematic appraisal tools. The questionnaire improvement model comprises three stages: pretesting, redesign, and field-testing. The survey was evaluated by 13 expert reviewers, using a modified version of the Questionnaire Appraisal System (QAS-99). Based on the results of pretesting, survey questions were modified at a group meeting of experts. To identify potential issues with the improved survey questions, data were collected from 20 interviews and 31 respondents before behavior coding analysis was conducted. The questionnaire improvement model and systematic appraisal tools were useful in identifying, evaluating, and correcting miscommunication and other similar issues in the KFODIS.

• The Journal of the Korea Contents Association
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• v.15 no.3
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• pp.303-317
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• 2015

Although the public health centers have been initiating health education recently, it is not extending as expected and the participation of the program is low. The reason is that the office workers have few opportunities to receive health education since there are few public health centers in relation to the population. Much time is required for travel and attendance of the classes. In order to solve this problem, the aim is to increase participation in health education, improve the overall public health awareness, expand the number of health education locations to reduce medical expenses, vitalize the lifelong educational health programs, and improve the national health insurance. In order to research about the health education expansion plan for public health improvement, a study focused on men and women above age 20 who need health education. The research sample was selected through random sampling that targeted people who participated in the health programs or the health education. The period of this survey was from September 1st to September 30th, 2014. A total of 509 participants completed the survey data for the actual analysis to propose the health education expansion plan for the public health improvement.

• Journal of The Korean Society of Inherited Metabolic disease
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• v.20 no.2
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• pp.44-49
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• 2020

Pseudohypoparathyroidism (PHP) is a disorder characterized by hypocalcemia and hyperphosphatemia due to end organ resistance to parathyroid hormone. PHP is caused by the deficiency of the α-subunit of the stimulatory G protein encoded by the GNAS gene, and this defect arises from genetic or imprinting disturbances. Sporadic PHP 1b shows two or more methylation defects of upstream of GNAS gene and some of them lead to loss of maternal GNAS imprints, therefore, only paternally derived GNAS gene is expressed. Here, we report a 10 year 9 month old boy presented with intermittent tetany who was finally diagnosed with PHP 1b caused by paternal uniparental disomy of chromosome 20q.

• Journal of Life Science
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• v.27 no.12
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• pp.1494-1499
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• 2017

Oral infection due to Candida albicans is a widely recognized and frequent cause of superficial infections of the oral mucosa (oral candidiasis). Although oral candidiasis is not a life-threatening fungemia, it can cause severe problems in individuals under certain conditions. MicroRNAs (miRNAs) are noncoding, small RNA molecules, which regulate the expression of other genes by inhibiting the translation of target mRNAs. The present study was designed to identify miRNAs in C. albicans and determine their possible roles in this organism. miRNA-sized small RNAs (msRNAs) were cloned in C. albicans by deep sequencing, and their secondary structures were analyzed. All the cloned msRNAs satisfied conditions required to qualify them as miRNAs. Bioinformatics analysis revealed that two of the most highly expressed C. albicans msRNAs, Ca-363 and Ca-2019, were located in the 3' untranslated region of the corticosteroid-binding protein 1 (CBP1) gene in a reverse orientation. miRNA mimics were transformed into C. albicans to investigate their RNA-inhibitory functions. RNA oligonucleotide-transformed C. albicans was then observed by fluorescent microscopy. Quantitative PCR analysis showed that these msRNAs did not inhibit CBP1 gene expression 4 hr and 8 hr after ectopic miRNA transformation. These results suggest that msRNAs in C. albicans possess an miRNA-triggered RNA interference gene-silencing function, which is distinct from that exhibited by other eukaryotic systems.

• Journal of Service Research and Studies
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• v.12 no.3
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• pp.26-44
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• 2022

Job stress experienced during work has a positive effect on the organization, such as performance improvement, but if not properly managed, it can cause physical diseases such as digestive diseases and mental diseases such as depression and neurological diseases. If job stress persists for a long time, it causes emotional exhaustion and depression, which has a significant adverse effect on individuals and organizations, so proper management is essential. Therefore, in this study, a descriptive survey study was conducted using a self-report questionnaire method to find out the relationship between job stress, emotional exhaustion and depression of medical institution workers. As a result of the analysis, it was found that job stress of medical institution workers had a significant (+) effect on emotional exhaustion and depression, and emotional exhaustion of medical institution workers had a significant (+) effect on depression. Through this study, it was found that there was a significant relationship between job stress, emotional exhaustion, and depression of hospital employees, and that emotional exhaustion acts as a parameter in the relationship between job stress and depression. Considering that job stress of hospital employees causes adverse organizational effects, such as threatening workers' mental and physical health and causing deterioration in the quality of medical services, organizational efforts will be needed to relieve and properly manage job stress of hospital employees.