• Journal of the Korean Society of Marine Environment & Safety
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• v.15 no.1
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• pp.41-48
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• 2009

In order to develop the standard service model of Korea Coast Guard at fishing port, which responses to the demand of users and provides them with the high quality service of maritime administration, the services performed by a branch of KCG are analyzed and the level of familiarity with them are investigated. The degree of affair achievement is quantitatively standardized by assessing the workload of branch office. The standard model of affairs is formatted and the programs of organization, resource operation and education are proposed.

• Journal of the Institute of Electronics Engineers of Korea CI
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• v.40 no.5
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• pp.289-297
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• 2003

The performance of a bimodal system is affected by the accuracy of the endpoint detection from the input signal as well as the performance of the speech recognition or lipreading system. In this paper, we propose the endpoint detection method which detects the endpoints from the audio and video signal respectively and utilizes the signal to-noise ratio (SNR) estimated from the input audio signal to select the reliable endpoints to the acoustic noise. In other words, the endpoints are detected from the audio signal under the high SNR and from the video signal under the low SNR. Experimental results show that the bimodal system using the proposed endpoint detector achieves satisfactory recognition rates, especially when the acoustic environment is quite noisy.

• Journal of KIISE:Computer Systems and Theory
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• v.35 no.6
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• pp.237-247
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• 2008

A virtual screening is the process of reducing an unmanageable number of compounds to a limited number of compounds for the target of interest by means of computational techniques such as molecular docking. And it is one of a large-scale scientific application that requires large computing power and data storage capability. Previous applications or softwares for molecular docking such as AutoDock, FlexX, Glide, DOCK, LigandFit, ViSION were developed to be run on a supercomputer, a workstation, or a cluster-computer. However the virtual screening using a supercomputer has a problem that a supercomputer is very expensive and the virtual screening using a workstation or a cluster-computer requires a long execution time. Thus we propose a service-based virtual screening system using Grid computing technology which supports a large data intensive operation. We constructed 3-dimensional chemical molecular database for virtual screening. And we designed a resource broker and a data broker for supporting efficient molecular docking service and proposed various services for virtual screening. We implemented service based virtual screening system with DOCK 5.0 and Globus 3.2 toolkit. Our system can reduce a timeline and cost of drug or new material design.

• Journal of the korean academy of Pediatric Dentistry
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• v.40 no.4
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• pp.321-327
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• 2013

Ameloblastic fibroma (AF) is a rare odontogenic ectomesenchymal tumor that is frequently seen in the first two decades of life, and occurs in the mandible. The most proper management of AF has been a recent topic of debate because of its recurrence and malignant transformation. This report describes AF in a 4-year-old male, which was a unilocular radiolucency on the maxillary right primary molar area with a scalloped border and corticated margin. The tumor was treated conservatively with enucleation and curettage, and the decision was made to preserve the right primary second molar. A biopsy confirmed it as AF. During the 43 months of follow-up, the patient had no evidence of recurrence or malignant transformation. Moreover, the radiographic examination revealed the generation of tooth germ to be a permanent second premolar. This report shows a case of AF in the posterior maxilla of a 4-year-old boy and discusses the conservative therapeutic approach to this tumor. Therefore, the age of the patients should be an important consideration when choosing conservative or radical surgery in a young AF patient.

• Journal of Dental Rehabilitation and Applied Science
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• v.29 no.4
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• pp.347-358
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• 2013

When analyzing soft tissue of the profile, Subnasale is often used as an important reference point. But there are few studies on the ideal position of the Subnasale. Therefore, the purpose of this study is to present an objective reference of the esthetic face relating to the change of Subnasale position in Koreans' profile, and also to determine whether there is concordance between professionals and laypersons in their perception of facial attractiveness. The one determined as appropriate profile portion by experts of pictures taken in women in 20s was selected. The photograph was modified changing the Subnasale anteroposteriorly on the plane perpendicular to the true vertical line, while maintaining the nasolabial angle. The photographs were presented to a group of professionals (9 orthodontists) and 126 laypersons, who were asked to assess the facial attractiveness of the photographs on a VAS independently. The conclusion was obtained. 1. The ideal position of the Subnasale is when the ratio of the distance Lateral canthus~Subnasale : Subnasale~Pronasale is 1.769 : 1. 2. The ideal degrees between the true vertical line passing through Nasion and Subnasale is $5.5^{\circ}$ 3. The professionals recognized every change in the ratio, but the laypersons couldn't differentiate between the change from 1.571 : 1 to 1.769 : 1.

• The Korean Journal of Nuclear Medicine Technology
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• v.20 no.2
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• pp.54-61
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• 2016

Purpose Precocious Puberty is defined as the development of secondary sexual characteristics in girls younger than 8 years, and boys 9 years. Cause premature closure of the epiphysis is a disease that eventually decreases the final adult height. In this study, we retrospectively analyzed to evaluate the diagnostic difference the GnRH (Gonado-tropin-releasing Hormone) stimulation test results with medical records of precocious puberty in girls. Materials and Methods From February 2015 to December 2015 it was enrolled in the girls 118 people who visited the Seoul National University Bundang Hospital, Pediatrics, Endocrinology Internal Medicine. True precocious puberty group (n=57), early puberty group (n=39), were divided into Premature thelarche (n=22) group. A Tanner stage, chronological age, bone age, height, body weight for each group was determined by examining the mean${\pm}$standard deviation. GnRH test result was compared LH (Basal, 30 min, 45 min, 60 min), FSH (Basal, 30 min, 60 min) for each group, Each group LH, FSH Peak value distribution, the mean${\pm}$standard deviation was calculated for the peak LH/LH basal ratio, peak LH/Peak FSH ratio. The significance probability (P-value) between the value of each third group was determined. Results The average height of the true precocious puberty group $131{\pm}14.85$, the mean weight was $28.80{\pm}4.93$, the average chronological age $7.1{\pm}0.81$, the mean bone age was $9.9{\pm}0.9$, The average height of early puberty group was $134{\pm}5.10$, the average weight $28.50{\pm}4.43$, the average chronological age $8.05{\pm}0.03$, the mean bone age was $10.0{\pm}0.62$, The average height of Premature thelarche $129{\pm}6,01$, the average weight was $28.65{\pm}5.98$, the average chronological age $7.02{\pm}0.58$, the mean bone age was $8.04{\pm}1.29$. There was no significant difference when compared to the height and weight. There was a significant difference between the groups in the chronologic age and bone age difference (P <0.0002) True precocious puberty group showed peak LH levels at 30'(82.5%), 45'(12.3%), 60'(5.3%), in Peak FSH 30'(8.8%), 60'(91.2%). Early Puberty group showed high values in Peak LH at 30'(79.5%), 45'(17.9%), 60'(2.6%), in peak FSH levels at 30'(7.7%), 60'(92.32%). In Premature thelarche Group it showed the Peak LH levels at 30'(30%), 45'(59%), 60'(9.09%), Peak FSH levels at 30'(0%) 60'(100%). When compared with the The Peak LH/basal LH ratio, True precocious puberty group was $19.09{\pm}17.15$, early puberty group was $15.23{\pm}10.88$, Premature thelarche group showed significant differences between the three groups as $4.93{\pm}4.36$.(P <0.0001) LH Peak/FSH Peak ratio, true precocious puberty group was $1.222{\pm}0.77$, early puberty group was $1.34{\pm}1.23$, Premature thelarche group showed significant differences between the three groups as $0.3{\pm}0.09$(P <0.0001) Conclusion In order to diagnose the true precocious puberty have a diagnostic value when the LH peak after GnRH stimulation is increased by more than two to three times compared to baseline or a predetermined level or more than 5~10 IU/L increases. GnRH Test is a test for a long time and the patient discomfort due to repeated blood sampling, but the hypothalamus-pituitary gland- gonad axis activity evaluate and is the most basic accurate test in the differential diagnosis of precocious puberty disorders.

• The Journal of Internal Korean Medicine
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• v.26 no.2
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• pp.302-309
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• 2005

Background : Death by cancer, malignant tumor, is on the increase around the world. In South Korea, cancer is the number one cause of death, and, in South Korea, stomach cancer is the most common form of cancer. This may be due to genetic and enviornmental factors. Because stomach cancer is so prevalent here, this study was undertaken. Objectives: This study was conducted to investigate the anti-cancer effects of Duchesnea indica(Andr.) Focke. in human stomach cancer cells(KATOIII). Materials & Methods: For human stomach cancer cells KATO III cells were obtained from Korea Cell Line Bank. The water decoction of Duchesnea indica(Andr.) Focke was added to cultures. First, morphological changes were examined under an inverted microscope. The destruction of stomach cancer cells was measured through Trypan blue exclusion testing, and suppression of viability of stomach cancer cells was measured via MTT assay. Anti-cancer mechanisms were assessed by analyzing the cell cycle. Results & Conclusions : In morphologic change, stomach cancer cells showed the withdrawn and floating appearance that is typical in cellular impairment. In each test group more stomach cancer cells were killed than in the control group to a statistically significant degree. Each test group showed more suppression of viability of stomach cancer cells than that of the control group to a statistically significant degree. Analysis of the cell cycle showed that Duchesnea indica(Andr.) Focke inhibited division of stomach cancer cells. This experiment yielded empirical evidence for Duchesnea indica(Andr.) Focke as a statistically significant anticarcinogen, specifically against stomach cancer.

• Proceedings of the Korea Water Resources Association Conference
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• 2008.05a
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• pp.1142-1146
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• 2008

토양수분은 지표수의 유출과정을 설명하는 과정에서 중요인자이며, 생태수문학의 핵심변수이자 기상모형의 결정적인 입력변수이다. 또한 토양수분의 공간적 시간적 특징들은 강우 및 지하수와 토양수분간의 순환 구조를 규명하는데 매우 중요하다. 본 연구에서는 산지사면의 토양수분을 체계적으로 측정하는데 필요한 시스템의 구축을 위한 기초조사 및 사전분석에 대한 연구를 수행하였다. 우수한 토양 수분 측정 장비인 TDR 장비 매설에 앞서 대상유역 선정에 대한 여러 가지 고려사항을 검토하고 수치지형 분석 등을 통한 사전분석을 실시하였다. 대상유역을 선정하기 위해서는 대상유역의 자료획득의 용이함, 지정학적, 시스템 운영적 측면에서의 가용성, 그리고 정밀측량 및 부수적요인 등 여러 요소의 고려가 요구된다. 본 연구에서는 경기도 파주시 적성면 설마리의 설마천 유역내 감악산 범륜사 우측 산지 사면을 측정대상 사면으로, 지정학적 위치, 식생분포, 지질구조 및 심도 등의 토양특성의 고려를 통해서 선정하였다. 또한 대상 사면에 흐름 발생 및 분포를 계산하기 위해서 대상사면의 지표 및 기반암 표고를 정밀 측량하였으며, 기반암 또는 풍화대까지의 깊이를 실측하여 지표면 및 지하면의 수치지형 모형을 구축하였다. 이를 대상사면 및 지하면에 대하여 표고수치지형모형(Digital Elevation Model:DEM)으로 도식한 후 흐름 발생 공간 분포를 계산하였다. 흐름발생공간분포예측은 단방향 알고리즘, 다방향 알고리즘, 흐름 분배 알고리즘 그리고 다중무한방향 알고리즘을 사용하여 지형인자인 기여사면적과 지형습윤지수를 계산하였다. 각 분배알고리즘의 의해 도출된 지형인자들로 인한 흐름발생 공간적 분포특성을 비교하였다. 이는 합리적인 토양수분 측정시스템을 구축하는데 중요한 의사결정 수단으로 판단된다.

• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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• v.11 no.1
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• pp.76-80
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• 2000

Tongue-tip trill is a sound made by the tongue tip making contract with the alveolar ridge and oscillating rapidly as sound is produced. It is an exercise used by many singers to warm up the voice and used as one of the methods of voice rehabilitation for patients who have the vocal folds scarred postoperatively and also who present with a variety of disorders, particularly hypofunction and presbyphonia. We intended to investigate the mucosal vibration of the true vocal folds on tongue-tip trill by electroglottography and to find e effective methods of tongue-tip trill. One adult male volunteer participated. Spectrography and electroglottography were checked repeatedly 15 times, more than 5 second in each times, at same pitch, in three conditions of phonation : sustained /a/ vowel, anterior trill in which tongue-tip vibrated at anterior portion of alveolar ridge just behind the anterior tooth, and posterior trill in which at palatal crest behind the transverse palatine fold We measured the first and second formant to determine indirectly the position of tongue and calculated speed quotient and the ratio of closing phase to closed phase. Speed quotients of posterior trill were higher than sustained /a/ vowel and anterior trill in 14 times. The ratio of closing phase to dosed phase of posterior trill were lower than the others in 14 times. Mucosa of true vocal folds is vibrated more effectively on posterior trill rather than sustained /a/ vowel and anterior trill. So, when tongue-tip trill is used as a method of voice rehabilitation, we suggest that posterior trill is better in producing effective mucosal vibration

• Journal of the Korean Vacuum Society
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• v.7 no.4
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• pp.397-402
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• 1998

$SiO_2$ etch characteristics were studied as a function of the basic parameters, such as the main RF power and the operating pressure in a helicon plasma. $SiO_2$ etch characteristics were improved as the main RF power was increased and the operating pressure was decreased. $SiO_2$ etch selectivity over silicon increased from 2.9 to 25.33 when the RF input power increased from 300 W to 2 kW and from 2.3 to 16.21 when the operating pressure decreased from 10 mTorr to 1.5 mTorr with $C_4F_8$ plasma. We used a quadrupole mass spectrometer to measure the relative abundancies of various ionic and radical species to explain the experimental results and found that when the operating pressure is low and the RF input power is high, the highly selective $SiO_2$ etch is achieved as a result of density increment of the densities of various ionic species.