• Title/Summary/Keyword: 지방생성

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Method to improve the Quality of Training Data for Automatic Summarization of Judgments (판결문 자동요약을 위한 학습 데이터의 품질 개선방안)

  • Sang-Young Go
    • Annual Conference on Human and Language Technology
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    • 2022.10a
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    • pp.461-464
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    • 2022
  • 법원도서관이 발간하는 판례공보를 기반으로 판결문 자동요약을 위한 학습 데이터들이 구축되고 있다. 그런데 판결문 요약에서는 뉴스 요약과는 달리 추출요약과 생성요약 방식이 함께 사용되는 특수성이 있고, 이러한 특수성 때문에 현재 판결문 요약 데이터셋이 요약 프로그램의 성능 향상을 이끌지 못하고 있다고 생각된다. 따라서 법률가들이 판결문을 요약하는 방식을 반영하여, 추출요약 방식으로 작성된 판결요지와 생성요약 방식으로 작성된 판결요지를 분리해서 요약 데이터셋을 만들 필요가 있다. 추출요약과 생성요약에 관한 데이터셋을 따로 구축하기 위해서는 판례공보의 판결요지를 추출요약과 생성요약으로 분류하는 작업이 필요한데, 감성 분석에 사용되는 알고리즘이 판결요지의 분류 작업에 응용될 수 있다는 것을 실험 결과로 알 수 있었다.

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Inhibition of Adipocyte Differentiation and Adipogenesis by Aged Black Garlic Extracts in 3T3-L1 Preadipocytes (흑마늘 추출물에 의한 3T3-L1 지방전구세포의 분화 및 adipogenesis 억제에 관한 연구)

  • Park, Jung-Ae;Park, Cheol;Han, Min-Ho;Kim, Byung-Woo;Chung, Yoon-Ho;Choi, Yung-Hyun
    • Journal of Life Science
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    • v.21 no.5
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    • pp.720-728
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    • 2011
  • Garlic (Allium sativum) has been used as a source food as well as a traditional folk medicine ingredient since ancient times. Aged black garlic is a type of fermented garlic and is expected to have stronger anticancer and antioxidant activities than raw garlic. However, the mechanisms of their inhibitory effects on adipocyte differentiation and adipogenesis are poorly understood. In the present study, the effects and mechanisms of water extracts of raw garlic (WERG) and aged black garlic (WEABG) on adipocyte differentiation and adipogenesis in 3T3-L1 preadipocytes were investigated. Treatment with WEABG significantly suppressed terminal differentiation of 3T3-L1 preadipocytes in a dose-dependent manner as confirmed by a decrease in lipid droplet number and lipid content through Oil Red O staining, however WERG had no such effect. In addition, WEABG reduced accumulation of cellular triglyceride, which is associated with a significant inhibition of key pro-adipogenic transcription factors including peroxisome proliferator-activated receptor ${\gamma}$ (PPAR${\gamma}$), cytidine-cytidine-adenosine-adenosine-thymidine (CCAAT)/enhancer binding proteins ${\alpha}$ (C/EBP${\alpha}$) and C/EBP${\beta}$. Taken together, these results provide important new insight that aged black garlic might inhibit adipogenesis by suppressing the pro-adipogenic transcription factors in 3T3-L1 preadipocytes, and further studies will be needed to identify the active compounds that confer the anti-obesity activity of aged black garlic.

Identification of Greyish White Material Adhered to Shrouds from Tombs Covered with Lime of the Chosun Dynasty (조선시대 회곽 묘 출토 염습의에 부착된 회백색 물질의 동정)

  • OH, Joon-Suk;Yu, Hei-Sun;Yun, Eun-Young
    • Journal of Conservation Science
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    • v.16 s.16
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    • pp.21-26
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    • 2004
  • A lot of waterlogged shrouds and mummies have been found in tombs revered with lime of the Chosun Dynasty(1392-1910) of Korea. Shrouds were heavily polluted with greyish white material. Greyish white material, which adhered to shrouds excavated from tombs(16C and 17C), was submitted to FT-IR qualitative analysis and fatty acid analysis for cleaning. The results of the FT-IR qualitative analysis identified the main ingredient of the greyish white material as calcium salt of fatty acid, including a little of the fatty acids, lipids and proteins. Therefore the greyish white material fumed out adipocere which was formed from the degradation of the lipids in a dead body. From the fatty acid analysis, hydroxy fatty acids(10-Hydroxyhexadecanoic acid and 10-Hydroxyoctadecanoic acid), which were found in adipocere, were detected. The distribution of contents of fatty acids was also rimilar to that of adipocere which have a high proportion of palmitic acid of saturated fatty acid and a low proportion of oleic arid of unsaturated fatty acid. In view of the results of analyses, it was revealed that greyish white material adhered to shrouds was adipocere moved from a mummy.

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Effect of Polyphenolic Compounds from Green Tea Leaves on Production of Hydroperoxide for Lipid Oxidation in Corn Oil-in-Water Emulsion (녹차 페놀류가 corn oil-in-water emulsion의 산화 중 hydroperoxide 생성에 미치는 영향)

  • Cho, Young-Je;Kim, Byung-Gyu;Chun, Sung-Sook
    • Korean Journal of Food Science and Technology
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    • v.36 no.1
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    • pp.19-24
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    • 2004
  • Effect of polyphenolic compounds from green tea leaves and surfactant micelles on lipid oxidation in corn oil-in-water emulsion (O/W) wag determined. Concentrations of polyphenolic compound and surfactant in continuous phase of O/W were measured. Particle size of O/W with 17 mM Brij 700 and 5% corn oil increased with increasing concentration of polyphenolic compound (100-200 ppm). Concentration of surfactant in the continuous phase was lower than that of control. Lipid oxidation rates, as determined by the formation of lipid hydroperoxides and headspace hexanal, in O/W emulsions containing polyphenolic compounds decreased with increasing concentration of polyphenolic compounds (100-200 ppm). Inhibition of hydroperoxide and headspace hexanal produced via lipid oxidation by polyphenolic compounds in O/W was BHT>procyanidin B3-3-O-gallate>(+)-gallocatechin >(+)-catechin.

Reaction Kinetics between a Cycloaliphatic Diisocyanate(H12MDI) and n-Hexanol (환상지방족 Isocyanate(H12MDI)와 n-Hexanol의 반응속도론)

  • Kim, Taehoon;park, Sungyurb;Park, Sunghoon
    • Applied Chemistry for Engineering
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    • v.9 no.7
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    • pp.1079-1084
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    • 1998
  • Reaction kinetics between 4,4'-dihexyl methane diisocyanate($H_{12}MDI$) and n-hexanol in toluene with dibutyltin dilaurate(DBTDL) as catalyst was studied by experimental measurements and mathematical modeling. Experiments were carried out at various temperatures, catalyst concentrations and [NCO]/[OH] ratios, and the reaction kinetics were described by two second-order reactions, the one between NCO and OH leading to urethane and the other between urethane and NCO leading to allophanate. The rate constants were estimated by the Runge-Kutta 4th-order method. Experiments and mathematical simulations showed a good agreement for various experimental conditions. The [allophanate]/[urethane] ratios at 90% conversion of initial NCO were estimated to be over 20% for most conditions employed in the present study, indicating that allophanate formation might significantly affect the properties of urethane polymers.

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The Conditions Affecting Ethanol Tolerance of Yeast strains in Alcohol Ferwlentation - Study on the Aeration and Lipid Addition (알콜발효에서 효모의 에탄올 내성 조건-통기와 lipid첨가에 대한 연구)

  • 김형진;장형욱유연우
    • KSBB Journal
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    • v.4 no.2
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    • pp.172-176
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    • 1989
  • The alcohol fermentation was carried out to study the effect of aeration and unsaturated fatty acids added on the ethanol tolerance of Saccharomyces cerevisiae STV89 and Kluyveromyces fragilis CBS397. The cell growth rate and ethanol production rate was stimulated by aeration and the cell mass production and ethanol production were also substantially improved. With respect to strains, the maximum specific growth rate and overall ethanol productivity of K. fragilis under aerated condition were 6.4 fold and 4.4 fold higher than those of strictly anaerobic condition, although those of S. cerevisiae were increased 1.7 times and 2.3 times by aeration. The addition of ergosterol, linoleic acid and oleic acid also improved the cell growth and ethanol production of S. cerevisiae and K. fragilis. Thus it was found that oxygen and unsaturated fatty acids added played a decisive role on the increase of ethanol tolerance of yeast strains.

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Analysis of Radiolytic Compounds of Lipids for the Detection of Irradiation in Dried Mytilus coruscus (건조 홍합의 방사선 조사여부를 확인하기 위한 지방분해산물 분석)

  • Lee, Hae-Jung;Yun, Il-Nam;Seo, Hye-Young;Song, Hyun-Pa;Hong, Chul-Hee;Kim, Kyong-Su
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.31 no.4
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    • pp.599-603
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    • 2002
  • Radiolytic compounds of lipids, as hydrocarbons and 2-alkylcyclobutanones, were determined to detect the irradiated dried Mytilus coruscus. The detection methods were composed of fat extraction by Soxtec apparatus from dried Mytilus coruscus, isolation of hydrocarbons and 2-alkylcyclobutanones with a florisil column chromatography and identification of GC/MS. Concentrations of the radiation-induced hydrocarbons and 2-alkylcyclobutanones increased with the irradiation dose. The major hydrocarbons in irradiated Mytilus coruscus were pentadecane and 1-tetradecene originated from palmitic acid, and heptadecane and 1-hexadecene originated from stearic acid. 2-(5'- Tetradecenyl)cyclobutanone of 2-alkylcyclobutanones was high relatively. The radiation - induced hydrocarbons and 2-alkylcyclobutanones from dried Mytilus coruscus were detected at 0.5 kGy over and not detected at the non-irradiated.

Anti-adipogenic Effect of Fermented Coffee with Monascus ruber Mycelium by Solid-State Culture of Green Coffee Beans (3T3-L1 지방전구세포에서 홍국균 균사체-고체발효 원두커피 추출물의 지방축적 억제효과)

  • Lim, Yongrae;Shin, Ji-Young;Kim, Hoon;Baek, Gil-Hun;Yu, Kwang-Won;Jeong, Heon-Sang;Lee, Junsoo
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.43 no.4
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    • pp.624-629
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    • 2014
  • Obesity is the leading metabolic disease in industrialized countries and is closely associated with coronary heart disease, hypertension, diabetes, and cancer. The objective of this study was to evaluate the anti-adipogenic effects of two roasted coffee beans, Vietnam robusta (VR) and Ethiopia Mocha Sidamo G2 (ES), as well as fermented coffee beans with Monascus ruber (MR) mycelium on differentiation of 3T3-L1 preadipocytes. Treatments with 1,000 ${\mu}g/mL$ of hot water extract from coffee beans significantly reduced intracellular lipid accumulation. In addition, VR more effectively inhibited transcription factors such as $PPAR{\gamma}$, $C/EBP{\alpha}$, FAS, and aP2 compared to ES. Further, ES fermented with MR showed more effective anti-adipogenic activity than non-fermented ES. These results suggest that VR and ES inhibit adipocyte differentiation which may contribute to their anti-adipogenic properties.

Effects of Chongkukjang Intake on Lipid Metabolism and Liver Function in Alcoholic Fatty Liver Rats (청국장식이가 알코올성지방간 쥐의 지질대사 및 간 기능개선에 미치는 영향)

  • Lee, Eun-Hee;Chyun, Jong-Hee
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.38 no.11
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    • pp.1506-1515
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    • 2009
  • This study was performed to investigate the effect of chongkukjang intake on lipid metabolism and liver function in alcoholic fatty liver rats. Thirty-five 7-weeks old Spargue-Dawley male rats were used as experimental animals. After inducing alcoholic fatty liver, rats were divided into two groups and fed ethanol+casein diet (ECD) or ethanol+chongkukjang diet (EChD). At 10th, 20th and 30th days of the feeding experimental diet, rats were sacrificed to get blood and liver samples for analysis of blood lipids, lipid peroxides, antioxidative enzymes and biochemical indices of liver function. The mean food intake was not significantly different between ECD and EChD groups. Daily weight again of EChD group was significantly higher than that of ECD group at days 20 and 30. Serum total lipid, triglyceride and total cholesterol of ECD group were significantly higher than those of EChD group, while HDL-cholesterol was significantly higher in EChD group. Liver TBARS level of ECD group was significantly higher than that of EChD group. However, liver conjugated diene level was significantly higher in ECD group only at day 10. SOD, CAT and GPx activities of EChD group were significantly higher than those of ECD group at days 20 and 30. In the indices of liver function, GOT and GPT of ECD group were significantly higher than those of EChD group at day 10. LDH was significantly higher in ECD group. γ-GTP was significantly higher in ECD group only at day 20. Serum alcohol concentration of ECD group was significantly higher than that of EChD group at day 30. ADH and ALDH activities of EChD group were significantly higher than those of ECD group at day 30. Therefore, chongkukjang intake seems to give a beneficial effect on improving lipid metabolism and liver function by increasing HDL-cholesterol level, antioxidative enzyme activites, alcohol enzyme activities and decreasing serum lipids, liver TBARS and conjugated diene.

Antioxidant and Anti-adipogenic Effects of Kohlrabi and Radish Sprout Extracts (콜라비 새싹 추출물과 무순 추출물의 항산화 및 지방세포 분화 억제 활성)

  • Lee, Young-Jun;Kim, Jae-Hwan;Oh, Ji-Won;Shin, Gi-Hae;Lee, Jong Seok;Cho, Ju-Hyun;Park, Jin-Ju;Lim, Jeong-Ho;Lee, Ok-Hwan
    • Korean Journal of Food Science and Technology
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    • v.46 no.5
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    • pp.531-537
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    • 2014
  • Common cruciferous vegetables, kohlabi (Brassica oleracea) and radish (Raphanus sativus), contain phytochemicals such as glucosinolates and carotenoids. Therefore, this study investigated the antioxidant and anti-adipogenic effects of kohlrabi sprout extract (KSE) and radish sprout extract (RSE). The total carotenoid and glucosinolate contents of KSE and RSE were $39.50{\pm}0.67$ and $76.73{\pm}2.75mg/g$, respectively. The total glucosinolate contents of KSE and RSE were $2.65{\pm}0.02$ and $8.13{\pm}0.54mg/g$, respectively. The in vitro-antioxidative activities of KSE and RSE were significantly increased in a dose-dependent manner. Furthermore, ${\beta}$-carotene and glucosinolate-enriched KSE and RSE significantly inhibited lipid accumulation and reactive oxygen species production during the adipogenesis of 3T3-L1 preadipocytes. These results suggest that glucosinolate-enriched KSE and RSE, especially RSE, can be used in the treatment of obesity and as a natural source of antioxidants.